| KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m[6]A reader YTHDC1 protein degradation. | KAP1 stabilizes MYCN mRNA and promotes neuroblastoma tumorigenicity by protecting the RNA m(6)A reader YTHDC1 protein degradation.
Yang Y, Zhang Y, Chen G, Sun B, Luo F, Gao Y, Feng H, Li Y., Free PMC Article | 07/17/2024 |
| YTHDC1-dependent m6A modification modulated FOXM1 promotes glycolysis and tumor progression through CENPA in triple-negative breast cancer. | YTHDC1-dependent m6A modification modulated FOXM1 promotes glycolysis and tumor progression through CENPA in triple-negative breast cancer.
Shen X, Zhong J, Yu P, Liu F, Peng H, Chen N., Free PMC Article | 07/7/2024 |
| Recruitment of PVT1 Enhances YTHDC1-Mediated m6A Modification of IL-33 in Hyperoxia-Induced Lung Injury During Bronchopulmonary Dysplasia. | Recruitment of PVT1 Enhances YTHDC1-Mediated m6A Modification of IL-33 in Hyperoxia-Induced Lung Injury During Bronchopulmonary Dysplasia.
Bao T, Liu X, Hu J, Ma M, Li J, Cao L, Yu B, Cheng H, Zhao S, Tian Z., Free PMC Article | 05/31/2024 |
| YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus. | YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus.
Dong D, Wei J, Wang W, Zhou H, Hong L, Ji G, Yang X., Free PMC Article | 04/8/2024 |
| KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells. | KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells.
Shan M, Liu D, Sun L, Yang M, He M, Zhang Y, Xiang L, Lu L, He H, Niu D, Chen L, Li S, Chen A, He F, Wang Y, Lian J. | 02/28/2024 |
| YTHDC1-Modified m6A Methylation of Hsa_circ_0102678 Promotes Keratinocyte Inflammation Induced by Cutibacterium acnes Biofilm through Regulating miR-146a/TRAF6 and IRAK1 Axis. | YTHDC1-Modified m6A Methylation of Hsa_circ_0102678 Promotes Keratinocyte Inflammation Induced by Cutibacterium acnes Biofilm through Regulating miR-146a/TRAF6 and IRAK1 Axis.
Zhou M, Liu Y, Xu H, Chen X, Zheng N, Duan Z, Ge Y, Li D, Lin T, Zeng R, Chen Q, Li M., Free PMC Article | 02/22/2024 |
| YTHDC1 as a tumor progression suppressor through modulating FSP1-dependent ferroptosis suppression in lung cancer. | YTHDC1 as a tumor progression suppressor through modulating FSP1-dependent ferroptosis suppression in lung cancer.
Yuan S, Xi S, Weng H, Guo MM, Zhang JH, Yu ZP, Zhang H, Yu Z, Xing Z, Liu MY, Ming DJ, Sah RK, Zhou Y, Li G, Zeng T, Hong X, Li Y, Zeng XT, Hu H., | 01/6/2024 |
| Low expression of m6A reader YTHDC1 promotes progression of ovarian cancer via PIK3R1/STAT3/GANAB axis. | Low expression of m6A reader YTHDC1 promotes progression of ovarian cancer via PIK3R1/STAT3/GANAB axis.
Wang X, Chen Q, Bing Z, Zhou S, Xu Z, Hou Y, Zhao Y, Zhao S, Wang T., Free PMC Article | 10/5/2023 |
| Alternative splicing of HOXB-AS3 underlie the promoting effect of nuclear m6A reader YTHDC1 on the self-renewal of leukemic stem cells in acute myeloid leukemia. | Alternative splicing of HOXB-AS3 underlie the promoting effect of nuclear m6A reader YTHDC1 on the self-renewal of leukemic stem cells in acute myeloid leukemia.
Wu C, Cui J, Huo Y, Shi L, Wang C. | 08/11/2023 |
| The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression. | The YTHDC1/GLUT3/RNF183 axis forms a positive feedback loop that modulates glucose metabolism and bladder cancer progression.
Yan B, Li X, Peng M, Zuo Y, Wang Y, Liu P, Ren W, Jin X., Free PMC Article | 07/19/2023 |
| WTAP activates MAPK signaling through m6A methylation in VEGFA mRNA-mediated by YTHDC1 to promote colorectal cancer development. | WTAP activates MAPK signaling through m6A methylation in VEGFA mRNA-mediated by YTHDC1 to promote colorectal cancer development.
Ye M, Chen J, Yu P, Hu C, Wang B, Bao J, Lu F, Zhong Y, Yan L, Kan J, Bai J, Tian Y, Tang Q. | 07/14/2023 |
| YTHDC1 positively regulates PTEN expression and plays a critical role in cisplatin resistance of bladder cancer. | YTHDC1 positively regulates PTEN expression and plays a critical role in cisplatin resistance of bladder cancer.
Su Y, Wang B, Huang J, Huang M, Lin T., Free PMC Article | 07/13/2023 |
| N6-methyladenosine reader protein YTHDC1 regulates influenza A virus NS segment splicing and replication. | N6-methyladenosine reader protein YTHDC1 regulates influenza A virus NS segment splicing and replication.
Zhu Y, Wang R, Zou J, Tian S, Yu L, Zhou Y, Ran Y, Jin M, Chen H, Zhou H., Free PMC Article | 05/18/2023 |
| Reduction of mRNA m[6]A associates with glucose metabolism via YTHDC1 in human and mice. | Reduction of mRNA m(6)A associates with glucose metabolism via YTHDC1 in human and mice.
Yang K, Sun J, Zhang Z, Xiao M, Ren D, Liu SM. | 04/10/2023 |
| YTHDC1 maintains trophoblasts function by promoting degradation of m6A-modified circMPP1. | YTHDC1 maintains trophoblasts function by promoting degradation of m6A-modified circMPP1.
Wang D, Guan H, Xia Y. | 03/29/2023 |
| The Effect of N6-Methyladenosine Regulators and m6A Reader YTHDC1-Mediated N6-Methyladenosine Modification Is Involved in Oxidative Stress in Human Aortic Dissection. | The Effect of N6-Methyladenosine Regulators and m6A Reader YTHDC1-Mediated N6-Methyladenosine Modification Is Involved in Oxidative Stress in Human Aortic Dissection.
Yin F, Liu K, Peng W, Jiang D, Zhang H, Guo P, Wu Y, Zhang X, Sun C, Wang Y, Wang H, Han Y., Free PMC Article | 03/1/2023 |
| Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression. | Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression.
Timcheva K, Dufour S, Touat-Todeschini L, Burnard C, Carpentier MC, Chuffart F, Merret R, Helsmoortel M, Ferré S, Grézy A, Couté Y, Rousseaux S, Khochbin S, Vourc'h C, Bousquet-Antonelli C, Kiernan R, Seigneurin-Berny D, Verdel A. | 12/24/2022 |
| Downregulation of the m[6]A reader protein YTHDC1 leads to islet beta-cell failure and diabetes. | Downregulation of the m(6)A reader protein YTHDC1 leads to islet β-cell failure and diabetes.
Li X, Yang Y, Chen Z. | 12/17/2022 |
| YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway. | YTHDC1 is downregulated by the YY1/HDAC2 complex and controls the sensitivity of ccRCC to sunitinib by targeting the ANXA1-MAPK pathway.
Li W, Ye K, Li X, Liu X, Peng M, Chen F, Xiong W, Wang Y, Zhu L., Free PMC Article | 08/27/2022 |
| Multiple Phosphorylations of SR Protein SRSF3 and Its Binding to m(6)A Reader YTHDC1 in Human Cells. | Multiple Phosphorylations of SR Protein SRSF3 and Its Binding to m(6)A Reader YTHDC1 in Human Cells.
Tatsuno T, Ishigaki Y., Free PMC Article | 05/21/2022 |
| Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing. | Overexpression of m6A-factors METTL3, ALKBH5, and YTHDC1 alters HPV16 mRNA splicing.
Cui X, Nilsson K, Kajitani N, Schwartz S., Free PMC Article | 04/2/2022 |
| YTHDC1 gene polymorphisms and neuroblastoma susceptibility in Chinese children. | YTHDC1 gene polymorphisms and neuroblastoma susceptibility in Chinese children.
Li Y, Lu T, Wang J, Zhuo Z, Miao L, Yang Z, Zhang J, Cheng J, Zhou H, Li S, Li L, He J, Li A., Free PMC Article | 02/19/2022 |
| A critical role of nuclear m6A reader YTHDC1 in leukemogenesis by regulating MCM complex-mediated DNA replication. | A critical role of nuclear m6A reader YTHDC1 in leukemogenesis by regulating MCM complex-mediated DNA replication.
Sheng Y, Wei J, Yu F, Xu H, Yu C, Wu Q, Liu Y, Li L, Cui XL, Gu X, Shen B, Li W, Huang Y, Bhaduri-McIntosh S, He C, Qian Z., Free PMC Article | 01/15/2022 |
| VIRMA contributes to non-small cell lung cancer progression via N(6)-methyladenosine-dependent DAPK3 post-transcriptional modification. | VIRMA contributes to non-small cell lung cancer progression via N(6)-methyladenosine-dependent DAPK3 post-transcriptional modification.
Xu Y, Chen Y, Yao Y, Xie H, Lu G, Du C, Cheng J, Zhou J. | 01/8/2022 |
| N(6)-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation. | N(6)-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation.
Cheng Y, Xie W, Pickering BF, Chu KL, Savino AM, Yang X, Luo H, Nguyen DT, Mo S, Barin E, Velleca A, Rohwetter TM, Patel DJ, Jaffrey SR, Kharas MG., Free PMC Article | 12/25/2021 |