| Cyclin F-EXO1 axis controls cell cycle-dependent execution of double-strand break repair. | Cyclin F-EXO1 axis controls cell cycle-dependent execution of double-strand break repair.
Yang H, Fouad S, Smith P, Bae EY, Ji Y, Lan X, Van Ess A, Buffa FM, Fischer R, Vendrell I, Kessler BM, D'Angiolella V., Free PMC Article | 08/15/2024 |
| EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells. | EXO1 and DNA2-mediated ssDNA gap expansion is essential for ATR activation and to maintain viability in BRCA1-deficient cells.
García-Rodríguez N, Domínguez-García I, Domínguez-Pérez MDC, Huertas P., Free PMC Article | 06/24/2024 |
| EXO1 protects BRCA1-deficient cells against toxic DNA lesions. | EXO1 protects BRCA1-deficient cells against toxic DNA lesions.
van de Kooij B, Schreuder A, Pavani R, Garzero V, Uruci S, Wendel TJ, van Hoeck A, San Martin Alonso M, Everts M, Koerse D, Callen E, Boom J, Mei H, Cuppen E, Luijsterburg MS, van Vugt MATM, Nussenzweig A, van Attikum H, Noordermeer SM. | 02/22/2024 |
| EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression. | EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression.
Wang Z, Chao Z, Wang Q, Zou F, Song T, Xu L, Ning J, Cheng F., Free PMC Article | 01/30/2024 |
| Dynamic regulation of EXO1 promotes the progression from liver fibrosis to HCC through TGF-beta1/Smad signaling feedback loop. | Dynamic regulation of EXO1 promotes the progression from liver fibrosis to HCC through TGF-β1/Smad signaling feedback loop.
Li M, Huang F, Zhu W, Peng Y, Xu F, Li W, Zhao Q, Liu L., Free PMC Article | 12/27/2023 |
| PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1. | PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1.
Lodovichi S, Quadri R, Sertic S, Pellicioli A. | 10/5/2023 |
| MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1. | MSH2-MSH3 promotes DNA end resection during homologous recombination and blocks polymerase theta-mediated end-joining through interaction with SMARCAD1 and EXO1.
Oh JM, Kang Y, Park J, Sung Y, Kim D, Seo Y, Lee EA, Ra JS, Amarsanaa E, Park YU, Lee SY, Hwang JM, Kim H, Schärer O, Cho SW, Lee C, Takata KI, Lee JY, Myung K., Free PMC Article | 06/29/2023 |
| The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression. | The FBXO32/ATR/ATM axis acts as a molecular switch to control the sensitivity of osteosarcoma cells to irradiation through its regulation of EXO1 expression.
Lu Y, Huang P, Li Y, Liu W, Li J, Zhao R, Feng H, Shi C, Cao G., Free PMC Article | 06/23/2023 |
| Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma. | Construction and validation of a hypoxia-related risk signature identified EXO1 as a prognostic biomarker based on 12 genes in lung adenocarcinoma.
Chen Q, Chen S, Wang J, Zhao Y, Ye X, Fu Y, Liu Y., Free PMC Article | 04/12/2023 |
| A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene. | A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene.
Gao Y, Guitton-Sert L, Dessapt J, Coulombe Y, Rodrigue A, Milano L, Blondeau A, Larsen NB, Duxin JP, Hussein S, Fradet-Turcotte A, Masson JY., Free PMC Article | 02/4/2023 |
| Bioinformatics Analysis and Experimental Study of Exonuclease 1 Gene in Lung Adenocarcinoma. | Bioinformatics Analysis and Experimental Study of Exonuclease 1 Gene in Lung Adenocarcinoma.
Wang S, Cai W, Li J, An W, Zheng H, Liao M. | 11/5/2022 |
| The Roles of EXO1 and RPA1 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy. | The Roles of EXO1 and RPA1 Polymorphisms in Prognosis of Lung Cancer Patients Treated with Platinum-Based Chemotherapy.
He J, Wang Z, Wang Y, Zou T, Li XP, Chen J., Free PMC Article | 10/29/2022 |
| Upregulation of exonuclease 1 caused by homology-dependent repair confers cisplatin resistance to gastric cancer cells. | Upregulation of exonuclease 1 caused by homology-dependent repair confers cisplatin resistance to gastric cancer cells.
Mao P, Wu S, Fan Y. | 10/1/2022 |
| FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair. | FANCD2-Associated Nuclease 1 Partially Compensates for the Lack of Exonuclease 1 in Mismatch Repair.
Kratz K, Artola-Borán M, Kobayashi-Era S, Koh G, Oliveira G, Kobayashi S, Oliveira A, Zou X, Richter J, Tsuda M, Sasanuma H, Takeda S, Loizou JI, Sartori AA, Nik-Zainal S, Jiricny J., Free PMC Article | 09/4/2021 |
| RBX1 prompts degradation of EXO1 to limit the homologous recombination pathway of DNA double-strand break repair in G1 phase. | RBX1 prompts degradation of EXO1 to limit the homologous recombination pathway of DNA double-strand break repair in G1 phase.
Xie Y, Liu YK, Guo ZP, Guan H, Liu XD, Xie DF, Jiang YG, Ma T, Zhou PK., Free PMC Article | 07/3/2021 |
| EXO1: A tightly regulated nuclease. | EXO1: A tightly regulated nuclease.
Sertic S, Quadri R, Lazzaro F, Muzi-Falconi M. | 03/28/2021 |
| Variants in Homologous Recombination Genes EXO1 and RAD51 Related with Premature Ovarian Insufficiency. | Variants in Homologous Recombination Genes EXO1 and RAD51 Related with Premature Ovarian Insufficiency.
Luo W, Guo T, Li G, Liu R, Zhao S, Song M, Zhang L, Wang S, Chen ZJ, Qin Y. | 02/20/2021 |
| Allosteric inhibition of human exonuclease1 (hExo1) through a novel extended beta-sheet conformation. | Allosteric inhibition of human exonuclease1 (hExo1) through a novel extended β-sheet conformation.
Umar AA, Liddell S, Hussain R, Siligardi G, Harris G, Carr S, Asiani K, Gowers DM, Odell M, Scott DJ. | 01/9/2021 |
| Exonuclease 1 (Exo1) Participates in Mammalian Non-Homologous End Joining and Contributes to Drug Resistance in Ovarian Cancer. | Exonuclease 1 (Exo1) Participates in Mammalian Non-Homologous End Joining and Contributes to Drug Resistance in Ovarian Cancer.
He D, Li T, Sheng M, Yang B., Free PMC Article | 01/9/2021 |
| PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells. | PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells.
Kim JJ, Lee SY, Choi JH, Woo HG, Xhemalce B, Miller KM., Free PMC Article | 10/31/2020 |
| EXO1 resection at G-quadruplex structures facilitates resolution and replication. | EXO1 resection at G-quadruplex structures facilitates resolution and replication.
Stroik S, Kurtz K, Lin K, Karachenets S, Myers CL, Bielinsky AK, Hendrickson EA., Free PMC Article | 09/12/2020 |
| proteins interacting with EXO1 were identified. | The human Exonuclease-1 interactome and phosphorylation sites.
Eid W, Hess D, König C, Gentili C, Ferrari S. | 06/20/2020 |
| duplex DNA contact by Exo1 is a general mechanism that controls its activation and that this mechanism is particularly important for digestion of duplex DNA whose nascent ssDNA is bound by replication protein A | DNA duplex recognition activates Exo1 nuclease activity.
Li Y, Shen J, Niu H., Free PMC Article | 04/4/2020 |
| Calcium-stimulated AMPK-dependent phosphorylation of Exo1 protects stressed replication forks from aberrant resection. | Ca(2+)-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection.
Li S, Lavagnino Z, Lemacon D, Kong L, Ustione A, Ng X, Zhang Y, Wang Y, Zheng B, Piwnica-Worms H, Vindigni A, Piston DW, You Z., Free PMC Article | 01/18/2020 |
| Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging | Polymorphisms of the DNA repair gene EXO1 modulate cognitive aging in old adults in a Taiwanese population.
Lin E, Kuo PH, Liu YL, Yang AC, Tsai SJ. | 01/11/2020 |