| Epigenetic Inactivation of alpha-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer. | Epigenetic Inactivation of α-Internexin Accelerates Microtubule Polymerization in Colorectal Cancer.
Li Y, Bai L, Yu H, Cai D, Wang X, Huang B, Peng S, Huang M, Cao G, Kaz AM, Grady WM, Wang J, Luo Y. | 03/6/2021 |
| reduced/loss of expression of alpha-internexin was closely related to tumors with aggressiveness and patient's adverse prognosis | Loss of expression and prognosis value of alpha-internexin in gastroenteropancreatic neuroendocrine neoplasm.
Wang Y, Chen Y, Li X, Hu W, Zhang Y, Chen L, Chen M, Chen J., Free PMC Article | 02/2/2019 |
| The proteins UCH-L1 and alpha-internexin could be independent prognostic biomarkers of pancreatic neuroendocrine tumors. | Prognostic relevance of UCH-L1 and α-internexin in pancreatic neuroendocrine tumors.
Song YL, Yu R, Qiao XW, Bai CM, Lu CM, Xiao Y, Zhong DR, Chen J, Zhao YP, Zhang TP, Song TT, Gao HL, Wan YH, Shen L, Chen J, Lv B, Hao JJ, Zhang Y, Tang L, Chen YJ., Free PMC Article | 12/22/2018 |
| Data suggest GRINL1A (GCOM1)-NMDA receptor-internexin-alpha (INA) interaction pathway may be relevant to neuroprotection. | The human GCOM1 complex gene interacts with the NMDA receptor and internexin-alpha.
Roginski RS, Lau CW, Santoiemma PP, Weaver SJ, Du P, Soteropoulos P, Yang J., Free PMC Article | 03/3/2018 |
| It is a neuronal marker, and has been indicated as an immunohistochemical surrogate of chromosome 1p/19q co-deletion in oligodendroglial tumors. | Coexpression of cyclin D1 and alpha-internexin in oligodendroglial tumors.
Matsumura N, Nobusawa S, Ikota H, Hirato J, Hirose T, Yokoo H, Nakazato Y. | 06/11/2016 |
| Gonadotropinomas, null cell pituitary adenomas, and thyrotropinomas exhibit high levels of intracellular INA protein indicating neuronal transdifferentiation. | Expression pattern of neuronal intermediate filament α-internexin in anterior pituitary gland and related tumors.
Schult D, Hölsken A, Buchfelder M, Schlaffer SM, Siegel S, Kreitschmann-Andermahr I, Fahlbusch R, Buslei R. | 03/26/2016 |
| It is a supportive diagnostic marker for oligodendroglial tumors with the 1p/19q co-deletion. | Alpha-internexin and altered CIC expression as a supportive diagnostic marker for oligodendroglial tumors with the 1p/19q co-deletion.
Nagaishi M, Suzuki A, Nobusawa S, Yokoo H, Nakazato Y. | 05/16/2015 |
| alpha-Internexin was expressed in 53% of 350 pancreatic neuroendocrine tumors. Reduced expression of alpha-internexin was significantly associated with advanced stage metastases, recurrence and shorter overall survival. | α-Internexin: a novel biomarker for pancreatic neuroendocrine tumor aggressiveness.
Liu B, Tang LH, Liu Z, Mei M, Yu R, Dhall D, Qiao XW, Zhang TP, Zhao YP, Liu TH, Xiao Y, Chen J, Xiang HD, Wu HY, Lu CM, Lv B, Zhou YR, Zhang Y, Deng D, Chen YJ. | 07/12/2014 |
| High INA expression is associated with grade II gliomas. | Molecular genetics of adult grade II gliomas: towards a comprehensive tumor classification system.
Figarella-Branger D, Bouvier C, de Paula AM, Mokhtari K, Colin C, Loundou A, Chinot O, Metellus P. | 04/13/2013 |
| INA may provide additional biologic information relevant to delineation of both pancreatic neuroendocrine neoplasms (NEN) tumor phenotypes and clinical behavior. | The clinical implications and biologic relevance of neurofilament expression in gastroenteropancreatic neuroendocrine neoplasms.
Schimmack S, Lawrence B, Svejda B, Alaimo D, Schmitz-Winnenthal H, Fischer L, Büchler MW, Kidd M, Modlin I., Free PMC Article | 06/23/2012 |
| the importance of alpha-internexin and NF-L in regulating the conformations of NF-M and NF-H | How the projection domains of NF-L and alpha-internexin determine the conformations of NF-M and NF-H in neurofilaments.
Leermakers FA, Zhulina EB. | 11/6/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
Grupe A, Li Y, Rowland C, Nowotny P, Hinrichs AL, Smemo S, Kauwe JS, Maxwell TJ, Cherny S, Doil L, Tacey K, van Luchene R, Myers A, Wavrant-De Vrièze F, Kaleem M, Hollingworth P, Jehu L, Foy C, Archer N, Hamilton G, Holmans P, Morris CM, Catanese J, Sninsky J, White TJ, Powell J, Hardy J, O'Donovan M, Lovestone S, Jones L, Morris JC, Thal L, Owen M, Williams J, Goate A., Free PMC Article | 12/2/2009 |
| Alpha-Internexin (INA) expression appears to be a simple, reliable prognostic marker and a surrogate marker of 1p19q codeletion. | alpha-Internexin expression identifies 1p19q codeleted gliomas.
Ducray F, Crinière E, Idbaih A, Mokhtari K, Marie Y, Paris S, Navarro S, Laigle-Donadey F, Dehais C, Thillet J, Hoang-Xuan K, Delattre JY, Sanson M. | 01/21/2010 |
| This protein has been found differentially expressed in the dorsolateral prefrontal cortex from patients with schizophrenia. | Proteomic analysis of dorsolateral prefrontal cortex indicates the involvement of cytoskeleton, oligodendrocyte, energy metabolism and new potential markers in schizophrenia.
Martins-de-Souza D, Gattaz WF, Schmitt A, Maccarrone G, Hunyadi-Gulyás E, Eberlin MN, Souza GH, Marangoni S, Novello JC, Turck CW, Dias-Neto E. | 12/29/2008 |
| Expression of the 2 markers, alpha-internexin and peripherin, in a small round cell tumor strongly favors the diagnosis of neuroblastoma. | A comparative immunohistochemical analysis of small round cell tumors of childhood: utility of peripherin and alpha-internexin as markers for neuroblastomas.
Willoughby V, Sonawala A, Werlang-Perurena A, Donner LR. | 01/21/2010 |
| The discovery of alpha-internexin in the cytoplasmic inclusions implicates novel mechanisms of pathogenesis in inclusion diseeae and other neurological diseases with pathological accumulations of IFs. | alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease.
Cairns NJ, Zhukareva V, Uryu K, Zhang B, Bigio E, Mackenzie IR, Gearing M, Duyckaerts C, Yokoo H, Nakazato Y, Jaros E, Perry RH, Lee VM, Trojanowski JQ., Free PMC Article | 01/21/2010 |
| alpha-internexin expression in neuroblastoma | Novel products of the HUD, HUC, NNP-1 and alpha-internexin genes identified by autologous antibody screening of a pediatric neuroblastoma library.
Behrends U, Jandl T, Golbeck A, Lechner B, Müller-Weihrich S, Schmid I, Till H, Berthold F, Voltz R, Mautner JM. | 01/21/2010 |
| Abnormal neuronal intermediate filament inclusions of alpha-internexin have been identified as the pathological hallmark of neuronal intermediate filament inclusion disease | Topography of alpha-internexin-positive neuronal aggregates in 10 patients with neuronal intermediate filament inclusion disease.
Armstrong RA, Cairns NJ. | 01/21/2010 |