White matter hyperintensity genetic risk factor TRIM47 regulates autophagy in brain endothelial cells. | White matter hyperintensity genetic risk factor TRIM47 regulates autophagy in brain endothelial cells. Yeung SH, Lee RH, Cheng GW, Ma IW, Kofler J, Kent C, Ma F, Herrup K, Fornage M, Arai K, Tse KH. | 10/7/2024 |
TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin-proteasome system. | TRIM47-CDO1 axis dictates hepatocellular carcinoma progression by modulating ferroptotic cell death through the ubiquitin‒proteasome system. Zhang J, Yimamu M, Cheng Z, Ji J, Wu L, Feng J, Xu X, Wu J, Guo C. | 06/28/2024 |
TRIM47 promotes glioma angiogenesis by suppressing Smad4. | TRIM47 promotes glioma angiogenesis by suppressing Smad4. Wang Z, Li Z, Han C, Cheng Y, Wang K. | 12/3/2022 |
TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling. | TRIM47 promotes ovarian cancer cell proliferation, migration, and invasion by activating STAT3 signaling. Wang X, Fu Y, Xing Y., Free PMC Article | 11/5/2022 |
TRIM47 accelerates aerobic glycolysis and tumor progression through regulating ubiquitination of FBP1 in pancreatic cancer. | TRIM47 accelerates aerobic glycolysis and tumor progression through regulating ubiquitination of FBP1 in pancreatic cancer. Li L, Yu Y, Zhang Z, Guo Y, Yin T, Wu H, Yang M. | 01/15/2022 |
TRIM47 activates NF-kappaB signaling via PKC-epsilon/PKD3 stabilization and contributes to endocrine therapy resistance in breast cancer. | TRIM47 activates NF-κB signaling via PKC-ε/PKD3 stabilization and contributes to endocrine therapy resistance in breast cancer. Azuma K, Ikeda K, Suzuki T, Aogi K, Horie-Inoue K, Inoue S., Free PMC Article | 12/18/2021 |
Upregulated Tripartite Motif 47 Could Facilitate Glioma Cell Proliferation and Metastasis as a Tumorigenesis Promoter. | Upregulated Tripartite Motif 47 Could Facilitate Glioma Cell Proliferation and Metastasis as a Tumorigenesis Promoter. Ji B, Liu L, Guo Y, Ming F, Jiang J, Li F, Zhao G, Wen J, Li N., Free PMC Article | 09/25/2021 |
Knockdown of TRIM47 inhibits glioma cell proliferation, migration and invasion through the inactivation of Wnt/beta-catenin pathway. | Knockdown of TRIM47 inhibits glioma cell proliferation, migration and invasion through the inactivation of Wnt/β-catenin pathway. Chen L, Li M, Li Q, Xu M, Zhong W. | 07/17/2021 |
Trim47 overexpression correlates with poor prognosis in gastric cancer. | Trim47 overexpression correlates with poor prognosis in gastric cancer. Xia Y, Wei Z, Huang W, Wei X, He Y. | 06/19/2021 |
our study has shown the biological and clinical significance of TRIM47 in colorectal cancer. TRIM47 exerts an inhibitory effect on SMAD4 by ubiquitylating and degrading SMAD4, thereby promoting tumor growth and progression. | TRIM47 is up-regulated in colorectal cancer, promoting ubiquitination and degradation of SMAD4. Liang Q, Tang C, Tang M, Zhang Q, Gao Y, Ge Z., Free PMC Article | 08/10/2019 |
Study shows that protein and gene expression level of TRIM47 are up-regulated in prostate neoplasm. | Increased Expression of Tripartite Motif (TRIM) 47 Is a Negative Prognostic Predictor in Human Prostate Cancer. Fujimura T, Inoue S, Urano T, Takayama K, Yamada Y, Ikeda K, Obinata D, Ashikari D, Takahashi S, Homma Y. | 10/21/2017 |
High TRIM47 expression is associated with non-small cell lung carcinoma. | TRIM47 overexpression is a poor prognostic factor and contributes to carcinogenesis in non-small cell lung carcinoma. Han Y, Tian H, Chen P, Lin Q., Free PMC Article | 10/14/2017 |
These results suggest that rs1055129 in TRIM47 is not associated with leukoaraiosis (LA) risk in the Chinese population. However, the association of rs1055129 (TRIM47) with LA before Bonferroni correction and Sidak correction is worth highlighting. | Analysis of genetic polymorphisms associated with leukoaraiosis in the southern Chinese population: A case-control study. Huang WQ, Ye HM, Li FF, Yi KH, Zhang Y, Cai LL, Lin HN, Lin Q, Tzeng CM., Free PMC Article | 02/18/2017 |