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    USP10 ubiquitin specific peptidase 10 [ Homo sapiens (human) ]

    Gene ID: 9100, updated on 29-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    USP10 promotes pancreatic ductal adenocarcinoma progression by attenuating FOXC1 protein degradation to activate the WNT signaling pathway.

    USP10 promotes pancreatic ductal adenocarcinoma progression by attenuating FOXC1 protein degradation to activate the WNT signaling pathway.
    Wang J, Gan L, Liu F, Yang Q, Deng Q, Jiang D, Zhang C, Zhang L, Wang X., Free PMC Article

    10/22/2024
    USP10 promotes cell proliferation, migration, and invasion in NSCLC through deubiquitination and stabilization of EIF4G1.

    USP10 promotes cell proliferation, migration, and invasion in NSCLC through deubiquitination and stabilization of EIF4G1.
    Li F, He Z, Zhang X, Gao D, Xu R, Zhang Z, Cao X, Shan Q, Liu Y, Xu Z., Free PMC Article

    10/21/2024
    FOXQ1, deubiquitinated by USP10, alleviates sepsis-induced acute kidney injury by targeting the CREB5/NF-kappaB signaling axis.

    FOXQ1, deubiquitinated by USP10, alleviates sepsis-induced acute kidney injury by targeting the CREB5/NF-κB signaling axis.
    Zhao Q, Zhang R, Wang Y, Li T, Xue J, Chen Z.

    08/22/2024
    Epidermal Growth Factor-Like Repeats and Discoidin I-Like Domains 3 Deficiency Attenuates Dilated Cardiomyopathy by Inhibiting Ubiquitin Specific Peptidase 10 Dependent Smad4 Deubiquitination.

    Epidermal Growth Factor-Like Repeats and Discoidin I-Like Domains 3 Deficiency Attenuates Dilated Cardiomyopathy by Inhibiting Ubiquitin Specific Peptidase 10 Dependent Smad4 Deubiquitination.
    Zhao M, Zheng Z, Peng S, Xu Y, Zhang J, Liu J, Pan W, Yin Z, Xu S, Wei C, Wang M, Wan J, Qin JJ., Free PMC Article

    03/20/2024
    Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling.

    Stabilization of MOF (KAT8) by USP10 promotes esophageal squamous cell carcinoma proliferation and metastasis through epigenetic activation of ANXA2/Wnt signaling.
    Li P, Yang L, Park SY, Liu F, Li AH, Zhu Y, Sui H, Gao F, Li L, Ye L, Zou Y, Tian Z, Zhao Y, Costa M, Sun H, Zhao X.

    03/18/2024
    Ubiquitin-specific peptidase 10 attenuates the ferroptosis to promote thyroid cancer malignancy by facilitating GPX4 via elevating SIRT6.

    Ubiquitin-specific peptidase 10 attenuates the ferroptosis to promote thyroid cancer malignancy by facilitating GPX4 via elevating SIRT6.
    Lian F, Dong D, Pu J, Yang G, Yang J, Yang S, Wang Y, Zhao B, Lu M.

    02/8/2024
    The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/beta-catenin signaling in cancer.

    The deubiquitinase USP10 mediates crosstalk between the LKB1/AMPK axis and Wnt/β-catenin signaling in cancer.
    Wang Y, Liu J, Zheng S, Cao L, Li Y, Sheng R.

    01/6/2024
    USP10 promotes the progression of triple-negative breast cancer by enhancing the stability of TCF4 protein.

    USP10 promotes the progression of triple-negative breast cancer by enhancing the stability of TCF4 protein.
    Yang JR, Lu YB, Su HX, Xiao Y, Pan Q, Su F, Zhang XB, Zhu KL, Guan QL, Ling XL.

    12/6/2023
    The formin DAAM1 regulates the deubiquitinase activity of USP10 and integrin homeostasis.

    The formin DAAM1 regulates the deubiquitinase activity of USP10 and integrin homeostasis.
    Phillips AT, Boumil EF, Venkatesan A, Tilstra-Smith C, Castro N, Knox BE, Henty-Ridilla JL, Bernstein AM., Free PMC Article

    12/1/2023
    Downregulated circPOKE promotes breast cancer metastasis through activation of the USP10-Snail axis.

    Downregulated circPOKE promotes breast cancer metastasis through activation of the USP10-Snail axis.
    Luo Y, Zhu Q, Xiang S, Wang Q, Li J, Chen X, Yan W, Feng J, Zu X.

    11/1/2023
    Hypoxia-induced long non-coding RNA LINC00460 promotes p53 mediated proliferation and metastasis of pancreatic cancer by regulating the miR-4689/UBE2V1 axis and sequestering USP10.

    Hypoxia-induced long non-coding RNA LINC00460 promotes p53 mediated proliferation and metastasis of pancreatic cancer by regulating the miR-4689/UBE2V1 axis and sequestering USP10.
    Zhang R, Wang X, Ying X, Huang Y, Zhai S, Shi M, Tang X, Liu J, Shi Y, Li F, Wang W, Deng X., Free PMC Article

    10/8/2023
    Deubiquitinating enzyme USP10 promotes osteosarcoma metastasis and epithelial-mesenchymal transition by stabilizing YAP1.

    Deubiquitinating enzyme USP10 promotes osteosarcoma metastasis and epithelial-mesenchymal transition by stabilizing YAP1.
    Deng J, Yi X, Feng Z, Peng J, Li D, Li C, Deng B, Liu S, Sahu S, Hao L., Free PMC Article

    07/21/2023
    INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10.

    INKILN is a Novel Long Noncoding RNA Promoting Vascular Smooth Muscle Inflammation via Scaffolding MKL1 and USP10.
    Zhang W, Zhao J, Deng L, Ishimwe N, Pauli J, Wu W, Shan S, Kempf W, Ballantyne MD, Kim D, Lyu Q, Bennett M, Rodor J, Turner AW, Lu YW, Gao P, Choi M, Warthi G, Kim HW, Barroso MM, Bryant WB, Miller CL, Weintraub NL, Maegdefessel L, Miano JM, Baker AH, Long X., Free PMC Article

    07/19/2023
    USP10 Contributes to Colon Carcinogenesis via mTOR/S6K Mediated HIF-1alpha but Not HIF-2alpha Protein Synthesis.

    USP10 Contributes to Colon Carcinogenesis via mTOR/S6K Mediated HIF-1α but Not HIF-2α Protein Synthesis.
    Kubaichuk K, Kietzmann T., Free PMC Article

    06/30/2023
    USP10 deubiquitinates RUNX1 and promotes proneural-to-mesenchymal transition in glioblastoma.

    USP10 deubiquitinates RUNX1 and promotes proneural-to-mesenchymal transition in glioblastoma.
    Qiu W, Xiao Z, Yang Y, Jiang L, Song S, Qi X, Chen Y, Yang H, Liu J, Chu L., Free PMC Article

    04/1/2023
    Stabilization of IGF2BP1 by USP10 promotes breast cancer metastasis via CPT1A in an m6A-dependent manner.

    Stabilization of IGF2BP1 by USP10 promotes breast cancer metastasis via CPT1A in an m6A-dependent manner.
    Shi J, Zhang Q, Yin X, Ye J, Gao S, Chen C, Yang Y, Wu B, Fu Y, Zhang H, Wang Z, Wang B, Zhu Y, Wu H, Yao Y, Xu G, Wang Q, Wang S, Zhang W., Free PMC Article

    02/15/2023
    Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/beta-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability.

    Melatonin inhibits ESCC tumor growth by mitigating the HDAC7/β-catenin/c-Myc positive feedback loop and suppressing the USP10-maintained HDAC7 protein stability.
    Ma ZQ, Feng YT, Guo K, Liu D, Shao CJ, Pan MH, Zhang YM, Zhang YX, Lu D, Huang D, Zhang F, Wang JL, Yang B, Han J, Yan XL, Hu Y., Free PMC Article

    10/8/2022
    USP10 deubiquitinates Tau, mediating its aggregation.

    USP10 deubiquitinates Tau, mediating its aggregation.
    Wei Z, Zeng K, Hu J, Li X, Huang F, Zhang B, Wang JZ, Liu R, Li HL, Wang X., Free PMC Article

    09/3/2022
    CircCOL1A2 Sponges MiR-1286 to Promote Cell Invasion and Migration of Gastric Cancer by Elevating Expression of USP10 to Downregulate RFC2 Ubiquitination Level.

    CircCOL1A2 Sponges MiR-1286 to Promote Cell Invasion and Migration of Gastric Cancer by Elevating Expression of USP10 to Downregulate RFC2 Ubiquitination Level.
    Li H, Chai L, Ding Z, He H., Free PMC Article

    08/6/2022
    Deubiquitinase ubiquitin-specific peptidase 10 maintains cysteine rich angiogenic inducer 61 expression via Yes1 associated transcriptional regulator to augment immune escape and metastasis of pancreatic adenocarcinoma.

    Deubiquitinase ubiquitin-specific peptidase 10 maintains cysteine rich angiogenic inducer 61 expression via Yes1 associated transcriptional regulator to augment immune escape and metastasis of pancreatic adenocarcinoma.
    Liu X, Chen B, Chen J, Su Z, Sun S., Free PMC Article

    05/28/2022
    USP10 inhibits the dopamine-induced reactive oxygen species-dependent apoptosis of neuronal cells by stimulating the antioxidant Nrf2 activity.

    USP10 inhibits the dopamine-induced reactive oxygen species-dependent apoptosis of neuronal cells by stimulating the antioxidant Nrf2 activity.
    Sango J, Kakihana T, Takahashi M, Katsuragi Y, Anisimov S, Komatsu M, Fujii M., Free PMC Article

    05/14/2022
    Loss of Ras GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) inhibits the progression of ovarian cancer in coordination with ubiquitin-specific protease 10 (USP10).

    Loss of Ras GTPase-activating protein SH3 domain-binding protein 1 (G3BP1) inhibits the progression of ovarian cancer in coordination with ubiquitin-specific protease 10 (USP10).
    Li M, Tang Y, Zuo X, Meng S, Yi P., Free PMC Article

    02/19/2022
    USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID.

    USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID.
    Luo Y, Zhang X, Chen R, Li R, Liu Y, Zhang J, Liu Q, Si M, Liu J, Wu B, Wang X, Wu S, Zhang Y, Zhang X, Guo D, He X, Pan T, Zhang H., Free PMC Article

    01/15/2022
    USP10 exacerbates neointima formation by stabilizing Skp2 protein in vascular smooth muscle cells.

    USP10 exacerbates neointima formation by stabilizing Skp2 protein in vascular smooth muscle cells.
    Xia X, Liu X, Chai R, Xu Q, Luo Z, Gu J, Jin Y, Hu T, Yu C, Du B, Huang H, Ou W, Liu S, Liu N., Free PMC Article

    12/18/2021
    The deubiquitinase USP10 restores PTEN activity and inhibits non-small cell lung cancer cell proliferation.

    The deubiquitinase USP10 restores PTEN activity and inhibits non-small cell lung cancer cell proliferation.
    He Y, Jiang S, Mao C, Zheng H, Cao B, Zhang Z, Zhao J, Zeng Y, Mao X., Free PMC Article

    11/22/2021
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