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    ANGPTL1 angiopoietin like 1 [ Homo sapiens (human) ]

    Gene ID: 9068, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Exosome-transmitted ANGPTL1 suppresses angiogenesis in glioblastoma by inhibiting the VEGFA/VEGFR2/Akt/eNOS pathway.

    Exosome-transmitted ANGPTL1 suppresses angiogenesis in glioblastoma by inhibiting the VEGFA/VEGFR2/Akt/eNOS pathway.
    Wang D, Li H, Zeng T, Chen Q, Huang W, Huang Y, Liao Y, Jiang Q.

    02/20/2024
    ANGPTL1 attenuates cancer migration, invasion, and stemness through regulating FOXO3a-mediated SOX2 expression in colorectal cancer.

    ANGPTL1 attenuates cancer migration, invasion, and stemness through regulating FOXO3a-mediated SOX2 expression in colorectal cancer.
    Chang TY, Lan KC, Chiu CY, Sheu ML, Liu SH., Free PMC Article

    05/14/2022
    Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.

    Exosomal ANGPTL1 attenuates colorectal cancer liver metastasis by regulating Kupffer cell secretion pattern and impeding MMP9 induced vascular leakiness.
    Jiang K, Chen H, Fang Y, Chen L, Zhong C, Bu T, Dai S, Pan X, Fu D, Qian Y, Wei J, Ding K., Free PMC Article

    08/28/2021
    Respiratory traits and coal workers' pneumoconiosis: Mendelian randomisation and association analysis.

    Respiratory traits and coal workers' pneumoconiosis: Mendelian randomisation and association analysis.
    Wang T, Sun W, Wu H, Cheng Y, Li Y, Meng F, Ni C.

    06/12/2021
    The findings demonstrate that lnc-ANGPTL1-3/miR-30a-3p/c-Maf axis plays a critical role in Multiple Myeloma bortezomib resistance.

    Long non-coding RNA ANGPTL1-3 promotes multiple myeloma bortezomib resistance by sponging miR-30a-3p to activate c-Maf expression.
    Nian F, Zhu J, Chang H.

    07/25/2020
    Low levels of ANGPTL1 is associated with colorectal cancer metastasis.

    ANGPTL1 attenuates colorectal cancer metastasis by up-regulating microRNA-138.
    Chen H, Xiao Q, Hu Y, Chen L, Jiang K, Tang Y, Tan Y, Hu W, Wang Z, He J, Liu Y, Cai Y, Yang Q, Ding K., Free PMC Article

    03/31/2018
    Aberrant expression of ANGPTL1 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.

    Aberrant expression of angiopoietin-like proteins 1 and 2 in cumulus cells is potentially associated with impaired oocyte developmental competence in polycystic ovary syndrome.
    Liu Z, Liu C, Hao C, Xue Q, Huang X, Zhang N, Bao H, Qu Q.

    05/13/2017
    Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis

    Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis.
    Udhane SS, Pandey AV, Hofer G, Mullis PE, Flück CE., Free PMC Article

    03/5/2016
    ANGPTL1 represses lung cancer cell motility by abrogating the expression of the epithelial mesenchymal transformation mediator SLUG.

    Angiopoietin-like protein 1 suppresses SLUG to inhibit cancer cell motility.
    Kuo TC, Tan CT, Chang YW, Hong CC, Lee WJ, Chen MW, Jeng YM, Chiou J, Yu P, Chen PS, Wang MY, Hsiao M, Su JL, Kuo ML., Free PMC Article

    05/18/2013
    Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)

    MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.
    Zhang X, Yang H, Lee JJ, Kim E, Lippman SM, Khuri FR, Spitz MR, Lotan R, Hong WK, Wu X., Free PMC Article

    12/5/2010
    Overexpression of angiopoietin 1 and metalloproteinases may be the characteristic feature of endometrium with greater potential to transform into endometriotic lesions in the peritoneal cavity.

    Metalloproteinases, vascular endothelial growth factor, and angiopoietin 1 and 2 in eutopic and ectopic endometrium.
    Di Carlo C, Bonifacio M, Tommaselli GA, Bifulco G, Guerra G, Nappi C.

    01/21/2010
    Immunohistochemical staining of Ang-1 was observed in smooth muscle cells, whereas Ang-2 was detected in endothelial cells, smooth muscle cells and macrophages.

    Balance between angiopoietin-1 and angiopoietin-2 is in favor of angiopoietin-2 in atherosclerotic plaques with high microvessel density.
    Post S, Peeters W, Busser E, Lamers D, Sluijter JP, Goumans MJ, de Weger RA, Moll FL, Doevendans PA, Pasterkamp G, Vink A.

    01/21/2010
    Inhibits experimental melanoma growth when transfected into murine cells.

    Recombinant angioarrestin secreted from mouse melanoma cells inhibits growth of primary tumours.
    Smagur A, Szary J, Szala S.

    01/21/2010
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