| Human splenic TER cells: A relevant prognostic factor acting via the artemin-GFRalpha3-ERK pathway in pancreatic ductal adenocarcinoma. | Human splenic TER cells: A relevant prognostic factor acting via the artemin-GFRα3-ERK pathway in pancreatic ductal adenocarcinoma.
Li TJ, Li H, Zhang WH, Xu SS, Jiang W, Li S, Gao HL, Han X, Xu HX, Wu CT, Wang WQ, Yu XJ, Liu L. | 08/7/2021 |
| Anti-amyloidogenic effect of artemin on alpha-synuclein. | Anti-amyloidogenic effect of artemin on α-synuclein.
Marvastizadeh N, Dabirmanesh B, Sajedi RH, Khajeh K. | 06/26/2021 |
| Attention-deficit/hyperactivity disorder risk alleles correlated with increased expression (and decreased methylation) of ARTN and PIDD1 and with a decreased expression (and increased methylation) of C2orf82. | Exploring genetic variation that influences brain methylation in attention-deficit/hyperactivity disorder.
Pineda-Cirera L, Shivalikanjli A, Cabana-Domínguez J, Demontis D, Rajagopal VM, Børglum AD, Faraone SV, Cormand B, Fernàndez-Castillo N., Free PMC Article | 07/18/2020 |
| In human skin, either with or without atopic dermatitis (AD), there was negative correlation between the staining intensity of HSD11beta1 and ARTN. The mechanism of skin sensitivity in AD could be explained partly by decreased HSD11beta1 expression and subsequent ARTN overexpression. | Attenuated Activation of Homeostatic Glucocorticoid in Keratinocytes Induces Alloknesis via Aberrant Artemin Production.
Matsumoto A, Murota H, Terao M, Katayama I. | 05/25/2019 |
| Artemin induced CXCR4 expression. | Artemin regulates CXCR4 expression to induce migration and invasion in pancreatic cancer cells through activation of NF-κB signaling.
Wang J, Wang H, Cai J, Du S, Xin B, Wei W, Zhang T, Shen X. | 01/5/2019 |
| Artemin could promote the proliferation and invasiveness of lung cancer cells in vitro and therefore could be a new potential target to combat lung cancer. | Role of artemin in non-small cell lung cancer.
Song Z, Yang F, Du H, Li X, Liu J, Dong M, Xu X., Free PMC Article | 12/22/2018 |
| The data suggest that ARTN and MMP-9 are involved in the occurrence, development, invasion and metastasis of EC, and play a synergistic role in the development of EC and lymphatic metastasis. | Expression and clinical significance of ARTN and MMP-9 in endometrial carcinoma.
Wang XH, Liu YN, Tian K, Yao CX, Li LM, Zheng YQ, Shi ZM. | 02/24/2018 |
| AhR activation and ARTN expression were positively correlated in the epidermis of patients with atopic dermatitis. | The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin.
Hidaka T, Ogawa E, Kobayashi EH, Suzuki T, Funayama R, Nagashima T, Fujimura T, Aiba S, Nakayama K, Okuyama R, Yamamoto M. | 07/1/2017 |
| Report the activity, pharmacokinetics, conformational dynamics and biophysical properties of different glycoforms of ART. | Investigating the Role of Artemin Glycosylation.
Danwen Q, Code C, Quan C, Gong BJ, Arndt J, Pepinsky B, Rand KD, Houde D. | 03/11/2017 |
| High ARTN increased xenograft tumor size and metastasis in hepatocellular carcinoma. | Artemin is hypoxia responsive and promotes oncogenicity and increased tumor initiating capacity in hepatocellular carcinoma.
Zhang M, Zhang W, Wu Z, Liu S, Sun L, Zhong Y, Zhang X, Kong X, Qian P, Zhang H, Lobie PE, Zhu T., Free PMC Article | 12/17/2016 |
| Artemin expression promotes invasiveness and neurotrophic function of pancreatic adenocarcinoma cells in vivo and in vitro | Neurotrophic Factor Artemin Promotes Invasiveness and Neurotrophic Function of Pancreatic Adenocarcinoma In Vivo and In Vitro.
Gao L, Bo H, Wang Y, Zhang J, Zhu M., Free PMC Article | 11/12/2016 |
| mRNA expression of Artemin (Artn) in the tongue mucosa of patients with burning mouth syndrome was significantly higher than that of control subjects. | Involvement of peripheral artemin signaling in tongue pain: possible mechanism in burning mouth syndrome.
Shinoda M, Takeda M, Honda K, Maruno M, Katagiri A, Satoh-Kuriwada S, Shoji N, Tsuchiya M, Iwata K. | 09/17/2016 |
| This is the first report of increased levels of a neurotrophic factor and of a glial cell line-derived neurotrophic factor family member in GAD patients. | BDNF and Artemin are increased in drug-naïve non-depressed GAD patients: preliminary data.
Pallanti S, Tofani T, Zanardelli M, Di Cesare Mannelli L, Ghelardini C. | 08/15/2015 |
| conclude that ARTN is one mediator of acquired resistance to trastuzumab in HER2-positive mammary carcinoma cells | Artemin, a member of the glial cell line-derived neurotrophic factor family of ligands, is HER2-regulated and mediates acquired trastuzumab resistance by promoting cancer stem cell-like behavior in mammary carcinoma cells.
Ding K, Banerjee A, Tan S, Zhao J, Zhuang Q, Li R, Qian P, Liu S, Wu ZS, Lobie PE, Zhu T., Free PMC Article | 10/11/2014 |
| The expression of GFRalpha1 and/or GFRalpha3, especially when combined with ARTN expression, may be useful predictors of disease progression and outcome in specific subtypes of mammary carcinoma. | Prognostic significance of the expression of GFRα1, GFRα3 and syndecan-3, proteins binding ARTEMIN, in mammary carcinoma.
Wu ZS, Pandey V, Wu WY, Ye S, Zhu T, Lobie PE., Free PMC Article | 06/15/2013 |
| ARTEMIN promotes de novo angiogenesis in ER negative mammary carcinoma through activation of TWIST1-VEGF-A signaling. | ARTEMIN promotes de novo angiogenesis in ER negative mammary carcinoma through activation of TWIST1-VEGF-A signalling.
Banerjee A, Wu ZS, Qian PX, Kang J, Liu DX, Zhu T, Lobie PE., Free PMC Article | 05/18/2013 |
| ARTN promotion of the cancer stem cell-like cell phenotype was mediated by TWIST1 regulation of BCL-2 expression. | Artemin stimulates radio- and chemo-resistance by promoting TWIST1-BCL-2-dependent cancer stem cell-like behavior in mammary carcinoma cells.
Banerjee A, Qian P, Wu ZS, Ren X, Steiner M, Bougen NM, Liu S, Liu DX, Zhu T, Lobie PE., Free PMC Article | 02/16/2013 |
| High artemin promotes motility and invasiveness of pancreatic cancer. | Neurotrophic artemin promotes motility and invasiveness of MIA PaCa-2 pancreatic cancer cells.
Meng LX, Chi YH, Wang XX, Ding ZJ, Fei LC, Zhang H, Mou L, Cui W, Xue YJ. | 01/26/2013 |
| artemin lowers the threshold of temperature-dependent itch sensation. | Artemin causes hypersensitivity to warm sensation, mimicking warmth-provoked pruritus in atopic dermatitis.
Murota H, Izumi M, Abd El-Latif MI, Nishioka M, Terao M, Tani M, Matsui S, Sano S, Katayama I. | 11/17/2012 |
| ARTN and TWIST1 synergize to produce a worse outcome in ER-MC and combined inhibition of ARTN and phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) may therefore provide a novel therapeutic strategy in this subtype of mammary carcinoma. | ARTEMIN synergizes with TWIST1 to promote metastasis and poor survival outcome in patients with ER negative mammary carcinoma.
Banerjee A, Wu ZS, Qian P, Kang J, Pandey V, Liu DX, Zhu T, Lobie PE., Free PMC Article | 06/30/2012 |
| Presenting an efficient method for the recombinant bacterial production of large quantities of highly pure, biologically active ARTN for in vitro and in vivo studies. | Recombinant expression, purification and dimerization of the neurotrophic growth factor Artemin for in vitro and in vivo use.
Bruinzeel W, Masure S. | 03/3/2012 |
| Studies indicate that artemin was highly expressed in squamous cell carcinoma lung cancer. | [Research advances of artemin].
Xun G, Guo F, Li Z, Zhou Q., Free PMC Article | 03/3/2012 |
| These results reveal that ARTN, a known tumor metastasis-related gene, is a direct target of miR-223. | miR-223 regulates migration and invasion by targeting Artemin in human esophageal carcinoma.
Li S, Li Z, Guo F, Qin X, Liu B, Lei Z, Song Z, Sun L, Zhang HT, You J, Zhou Q., Free PMC Article | 08/13/2011 |
| Forced expression of ARTN in ER-positive human mammary carcinoma cells increased ER transcriptional activity, promoted estrogen-independent growth and produced resistance to tamoxifen. | Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma.
Kang J, Qian PX, Pandey V, Perry JK, Miller LD, Liu ET, Zhu T, Liu DX, Lobie PE. | 10/4/2010 |
| ARTN increased BCL2 expression by transcriptional upregulation, and inhibition of BCL2 abrogated the oncogenic properties of ARTN in non-small cell lung carcinoma cells. | Artemin-stimulated progression of human non-small cell lung carcinoma is mediated by BCL2.
Tang JZ, Kong XJ, Kang J, Fielder GC, Steiner M, Perry JK, Wu ZS, Yin Z, Zhu T, Liu DX, Lobie PE. | 09/20/2010 |