| Identification of BANF1 as a novel prognostic biomarker in gastric cancer and validation via in-vitro and in-vivo experiments. | Identification of BANF1 as a novel prognostic biomarker in gastric cancer and validation via in-vitro and in-vivo experiments.
Xu Y, Wang X, Yuan W, Zhang L, Chen W, Hu K., Free PMC Article | 03/6/2024 |
| PYCR1, BANF1, and STARD8 Expression in Gastric Carcinoma: A Clinicopathologic, Prognostic, and Immunohistochemical Study. | PYCR1, BANF1, and STARD8 Expression in Gastric Carcinoma: A Clinicopathologic, Prognostic, and Immunohistochemical Study.
Harb OA, Elfeky MA, Alabiad MA, Hemeda R, Allam AS, El Hawary AT, Elbaz M, Sharaf AL, Gertallah LM, Abdelaziz AM, Shalaby AM, Alorini M, Yahia AIO, Negm M. | 02/22/2024 |
| RNA polymerase II promoter-proximal pausing promotes BAF chromatin binding and remodeling. | RNA polymerase II promoter-proximal pausing promotes BAF chromatin binding and remodeling.
Chick BY, Hargreaves DC. | 01/17/2024 |
| Hepatitis B Virus X Protein Inhibits the Expression of Barrier To Autointegration factor1 via Upregulating miR-203 Expression in Hepatic Cells. | Hepatitis B Virus X Protein Inhibits the Expression of Barrier To Autointegration factor1 via Upregulating miR-203 Expression in Hepatic Cells.
Mishra AK, Hossain MM, Sata TN, Yadav AK, Zadran S, Sah AK, Nayak B, Shalimar, Venugopal SK., Free PMC Article | 03/4/2023 |
| Barrier-to-autointegration factor 1 promotes gammaherpesvirus reactivation from latency. | Barrier-to-autointegration factor 1 promotes gammaherpesvirus reactivation from latency.
Broussard G, Ni G, Zhang Z, Li Q, Cano P, Dittmer DP, Damania B., Free PMC Article | 02/28/2023 |
| The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor-Guillermo progeria syndrome cells. | The BAF A12T mutation disrupts lamin A/C interaction, impairing robust repair of nuclear envelope ruptures in Nestor-Guillermo progeria syndrome cells.
Janssen A, Marcelot A, Breusegem S, Legrand P, Zinn-Justin S, Larrieu D., Free PMC Article | 11/19/2022 |
| An additional case of Nestor-Guillermo progeria syndrome diagnosed in early childhood. | An additional case of Néstor-Guillermo progeria syndrome diagnosed in early childhood.
Fisher HG, Patni N, Scheuerle AE. | 06/5/2021 |
| BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins. | BAF facilitates interphase nuclear membrane repair through recruitment of nuclear transmembrane proteins.
Young AM, Gunn AL, Hatch EM., Free PMC Article | 05/29/2021 |
| DNA unchained: two assays to discover and study inhibitors of the DNA clustering function of barrier-to-autointegration factor. | DNA unchained: two assays to discover and study inhibitors of the DNA clustering function of barrier-to-autointegration factor.
Burger M, Schmitt-Koopmann C, Leroux JC., Free PMC Article | 12/12/2020 |
| BAF restricts cGAS on nuclear DNA to prevent innate immune activation. | BAF restricts cGAS on nuclear DNA to prevent innate immune activation.
Guey B, Wischnewski M, Decout A, Makasheva K, Kaynak M, Sakar MS, Fierz B, Ablasser A. | 09/19/2020 |
| LEMD2 is required for recruitment of the ESCRT-III membrane repair machinery to ruptures; however, neither LEMD2 nor ESCRT-III is required to repair ruptures. These results reveal a new role for BAF in the response to and repair of nuclear ruptures. | Repair of nuclear ruptures requires barrier-to-autointegration factor.
Halfmann CT, Sears RM, Katiyar A, Busselman BW, Aman LK, Zhang Q, O'Bryan CS, Angelini TE, Lele TP, Roux KJ., Free PMC Article | 05/16/2020 |
| these data offer insight into Banf1-regulated, PARP1-directed repair of oxidative lesions. | Barrier-to-autointegration factor 1 (Banf1) regulates poly [ADP-ribose] polymerase 1 (PARP1) activity following oxidative DNA damage.
Bolderson E, Burgess JT, Li J, Gandhi NS, Boucher D, Croft LV, Beard S, Plowman JJ, Suraweera A, Adams MN, Naqi A, Zhang SD, Sinclair DA, O'Byrne KJ, Richard DJ., Free PMC Article | 02/29/2020 |
| Dimerization of barrier to autointegration factor 1 protein (BAF) is essential for both lamin A/C and emerin binding. | Structural analysis of the ternary complex between lamin A/C, BAF and emerin identifies an interface disrupted in autosomal recessive progeroid diseases.
Samson C, Petitalot A, Celli F, Herrada I, Ropars V, Le Du MH, Nhiri N, Jacquet E, Arteni AA, Buendia B, Zinn-Justin S., Free PMC Article | 07/13/2019 |
| Binding of fusion oncogene protein TMPRSS2-ERG to BAF chromatin remodeling complexes mediates prostate oncogenesis. | Binding of TMPRSS2-ERG to BAF Chromatin Remodeling Complexes Mediates Prostate Oncogenesis.
Sandoval GJ, Pulice JL, Pakula H, Schenone M, Takeda DY, Pop M, Boulay G, Williamson KE, McBride MJ, Pan J, St Pierre R, Hartman E, Garraway LA, Carr SA, Rivera MN, Li Z, Ronco L, Hahn WC, Kadoch C., Free PMC Article | 03/23/2019 |
| BAF and BAF-L might contribute to the shaping of the spermatozoon nucleus and, after fertilisation, its transition to the male pronucleus. | LEM-domain proteins are lost during human spermiogenesis but BAF and BAF-L persist.
Elkhatib RA, Paci M, Boissier R, Longepied G, Auguste Y, Achard V, Bourgeois P, Levy N, Branger N, Mitchell MJ, Metzler-Guillemain C. | 06/16/2018 |
| VRK1 and BANF1 yielded AUCs of 0.790 and 0.735, respectively. | Expression of VRK1 and the downstream gene BANF1 in esophageal cancer.
Li J, Wang T, Pei L, Jing J, Hu W, Sun T, Liu H. | 02/17/2018 |
| we demonstrate that BAF is necessary to modulate prelamin A effects on chromatin structure | Barrier-to-autointegration factor (BAF) involvement in prelamin A-related chromatin organization changes.
Loi M, Cenni V, Duchi S, Squarzoni S, Lopez-Otin C, Foisner R, Lattanzi G, Capanni C., Free PMC Article | 12/16/2017 |
| Findings support the value of using BioID to identify unrecognized constituents of distinct subcellular compartments refractory to biochemical isolation and reveal VRK2A as a transmembrane kinase in the NE that regulates BAF. | VRK2A is an A-type lamin-dependent nuclear envelope kinase that phosphorylates BAF.
Birendra Kc, May DG, Benson BV, Kim DI, Shivega WG, Ali MH, Faustino RS, Campos AR, Roux KJ., Free PMC Article | 11/18/2017 |
| It has been concluded that the LEM domain, responsible for binding to the chromatin protein BAF, undergoes a conformational change during self-assembly of emerin N-terminal region. | Emerin self-assembly mechanism: role of the LEM domain.
Samson C, Celli F, Hendriks K, Zinke M, Essawy N, Herrada I, Arteni AA, Theillet FX, Alpha-Bazin B, Armengaud J, Coirault C, Lange A, Zinn-Justin S. | 06/24/2017 |
| antiviral capabilities of the barrier to autointegration factor (BAF/BANF1) and how its function and regulation places BAF at the junction of multiple pathways protecting a cell's genetic integrity | The Barrier to Autointegration Factor: Interlocking Antiviral Defense with Genome Maintenance.
Wiebe MS, Jamin A., Free PMC Article | 08/6/2016 |
| The findings unveil a unique mechanism where the nuclear periphery proteins lamin-A/C, LAP2alpha and BAF1 are assembled into a protein complex during mitosis in order to regulate assembly and positioning of the mitotic spindle. | The lamin-A/C-LAP2α-BAF1 protein complex regulates mitotic spindle assembly and positioning.
Qi R, Xu N, Wang G, Ren H, Li S, Lei J, Lin Q, Wang L, Gu X, Zhang H, Jiang Q, Zhang C. | 06/28/2016 |
| results demonstrate a novel function of BAF as an epigenetic regulator of HSV lytic infection; hypothesize that BAF facilitates Herpes Simplex Virus IE and E gene expression by recruiting the SETD1A methyltransferase to viral IE and E gene promoters | Barrier-to-Autointegration Factor 1 (BAF/BANF1) Promotes Association of the SETD1A Histone Methyltransferase with Herpes Simplex Virus Immediate-Early Gene Promoters.
Oh HS, Traktman P, Knipe DM., Free PMC Article | 01/30/2016 |
| Vaccinia virus B1 kinase is needed for multiple critical junctures in the poxviral life cycle in a manner that is both dependent on and independent of BAF. | Vaccinia Virus B1 Kinase Is Required for Postreplicative Stages of the Viral Life Cycle in a BAF-Independent Manner in U2OS Cells.
Jamin A, Ibrahim N, Wicklund A, Weskamp K, Wiebe MS., Free PMC Article | 12/19/2015 |
| BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy. | BAF is a cytosolic DNA sensor that leads to exogenous DNA avoiding autophagy.
Kobayashi S, Koujin T, Kojidani T, Osakada H, Mori C, Hiraoka Y, Haraguchi T., Free PMC Article | 10/17/2015 |
| These data suggest that VRK3-mediated phosphorylation of BAF may facilitate DNA replication or gene expression by facilitating the dissociation of nuclear envelope proteins and chromatin during interphase. | Presumed pseudokinase VRK3 functions as a BAF kinase.
Park CH, Ryu HG, Kim SH, Lee D, Song H, Kim KT. | 08/29/2015 |