| Heterozygous pathogenic variants involving CBFB cause a new skeletal disorder resembling cleidocranial dysplasia. | Heterozygous pathogenic variants involving CBFB cause a new skeletal disorder resembling cleidocranial dysplasia.
Beyltjens T, Boudin E, Revencu N, Boeckx N, Bertrand M, Schütz L, Haack TB, Weber A, Biliouri E, Vinkšel M, Zagožen A, Peterlin B, Pai S, Telegrafi A, Henderson LB, Ells C, Turner L, Wuyts W, Van Hul W, Hendrickx G, Mortier GR., Free PMC Article | 04/26/2023 |
| Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer. | Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer.
Malik N, Kim YI, Yan H, Tseng YC, du Bois W, Ayaz G, Tran AD, Vera-Ramirez L, Yang H, Michalowski AM, Kruhlak M, Lee M, Hunter KW, Huang J., Free PMC Article | 04/19/2023 |
| The RUNX/CFBbeta Complex in Breast Cancer: A Conundrum of Context. | The RUNX/CBFβ Complex in Breast Cancer: A Conundrum of Context.
Khan AS, Campbell KJ, Cameron ER, Blyth K., Free PMC Article | 03/2/2023 |
| Mutual exclusivity between the fusion gene CBFB::MYH11 and somatic mitochondrial mutations in acute myeloid leukaemia. | Mutual exclusivity between the fusion gene CBFB::MYH11 and somatic mitochondrial mutations in acute myeloid leukaemia.
Zhao C, Wang S, Wang K. | 01/28/2023 |
| [Molecular Genetic Characteristics of Acute Myeloid Leukemia Patients with CBFbeta-MYH11 Positive]. | [Molecular Genetic Characteristics of Acute Myeloid Leukemia Patients with CBFβ-MYH11 Positive].
Jiang Y, Chao HY, Lu XZ, Wu P, Sun XC. | 12/17/2022 |
| Cancer-Associated Exosomal CBFB Facilitates the Aggressive Phenotype, Evasion of Oxidative Stress, and Preferential Predisposition to Bone Prometastatic Factor of Breast Cancer Progression. | Cancer-Associated Exosomal CBFB Facilitates the Aggressive Phenotype, Evasion of Oxidative Stress, and Preferential Predisposition to Bone Prometastatic Factor of Breast Cancer Progression.
Hsu CH, Ma HP, Ong JR, Hsieh MS, Yadav VK, Yeh CT, Chao TY, Lee WH, Huang WC, Kuo KT, Fong IH, Lin CC, Su CM., Free PMC Article | 08/6/2022 |
| TET2 deficiency cooperates with CBFB-MYH11 to induce acute myeloid leukaemia and represents an early leukaemogenic event. | TET2 deficiency cooperates with CBFB-MYH11 to induce acute myeloid leukaemia and represents an early leukaemogenic event.
Reckzeh K, Estruch M, Ali M, Søgaard Helbo A, Mosbech A, Jae Won K, Rücker F, Döhner K, Theilgaard-Mönch K. | 04/30/2022 |
| 3'CBFB deletion in CBFB-rearranged acute myeloid leukemia retains morphological features associated with inv(16), but patients have higher risk of relapse and may require stem cell transplant. | 3'CBFB deletion in CBFB-rearranged acute myeloid leukemia retains morphological features associated with inv(16), but patients have higher risk of relapse and may require stem cell transplant.
Tang G, Zou Y, Wang SA, Borthakur G, Toruner G, Hu S, Li S, Xu J, Medeiros LJ, Tang Z. | 03/19/2022 |
| Non-age-related neoplastic loss of sex chromosome correlated with prolonged survival in real-world CBF-AML patients. | Non-age-related neoplastic loss of sex chromosome correlated with prolonged survival in real-world CBF-AML patients.
Mori A, Onozawa M, Hidaka D, Yokoyama S, Miyajima T, Yokoyama E, Ogasawara R, Izumiyama K, Saito M, Fujisawa S, Ota S, Kakinoki Y, Tsutsumi Y, Yamamoto S, Miyagishima T, Nagashima T, Iwasaki H, Kobayashi H, Haseyama Y, Kurosawa M, Morioka M, Teshima T, Kondo T. | 02/19/2022 |
| Incidental identification of inv(16)(p13.1q22)/CBFB-MYH11 variant transcript in a patient with therapy-related acute myeloid leukemia by routine leukemia translocation panel screen: implications for diagnosis and therapy. | Incidental identification of inv(16)(p13.1q22)/CBFB-MYH11 variant transcript in a patient with therapy-related acute myeloid leukemia by routine leukemia translocation panel screen: implications for diagnosis and therapy.
Quesada AE, Luthra R, Jabbour E, Patel KP, Khoury JD, Tang Z, Alvarez H, Mallampati S, Garcia-Manero G, Montalban-Bravo G, Medeiros LJ, Kanagal-Shamanna R., Free PMC Article | 12/18/2021 |
| Core-binding factor leukemia hijacks the T-cell-prone PU.1 antisense promoter. | Core-binding factor leukemia hijacks the T-cell-prone PU.1 antisense promoter.
van der Kouwe E, Heller G, Czibere A, Pulikkan JA, Agreiter C, Castilla LH, Delwel R, Di Ruscio A, Ebralidze AK, Forte M, Grebien F, Heyes E, Kazianka L, Klinger J, Kornauth C, Le T, Lind K, Barbosa IAM, Pemovska T, Pichler A, Schmolke AS, Schweicker CM, Sill H, Sperr WR, Spittler A, Surapally S, Trinh BQ, Valent P, Vanura K, Welner RS, Zuber J, Tenen DG, Staber PB., Free PMC Article | 12/11/2021 |
| Circular RNA_0062582 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via regulation of microRNA-145/CBFB axis. | Circular RNA_0062582 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells via regulation of microRNA-145/CBFB axis.
Li F, Wu H, Zou G, Cang D, Shen Y., Free PMC Article | 12/4/2021 |
| CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer. | CBFB cooperates with p53 to maintain TAp73 expression and suppress breast cancer.
Malik N, Yan H, Yang HH, Ayaz G, DuBois W, Tseng YC, Kim YI, Jiang S, Liu C, Lee M, Huang J., Free PMC Article | 09/25/2021 |
| Multifaceted HIV-1 Vif interactions with human E3 ubiquitin ligase and APOBEC3s. | Multifaceted HIV-1 Vif interactions with human E3 ubiquitin ligase and APOBEC3s.
Hu Y, Knecht KM, Shen Q, Xiong Y., Free PMC Article | 07/24/2021 |
| Core-binding factor acute myeloid leukemia with inv(16): Older age and high white blood cell count are risk factors for treatment failure. | Core-binding factor acute myeloid leukemia with inv(16): Older age and high white blood cell count are risk factors for treatment failure.
Ustun C, Morgan EA, Ritz EM, Vestergaard H, Pullarkat S, Kluin PM, Ohgami R, Baughn LB, Kim Y, Ku NK, Czuchlewski D, Boe Møller M, Schiefer AI, Mrózek K, Horny HP, George TI, Kielsgaard Kristensen T, Beck T, Nathan S, Arana Yi C, Yeung C, Pullarkat V, Gotlib J, Akin C, Kohlschmidt J, Salhotra A, Soma L, Chen D, Han SY, Cho C, Sperr W, Broesby-Olsen S, Linden MA, Dolan M, Hoermann G, Hornick JL, Bloomfield C, Nakamura R, Joachim Deeg H, Litzow MR, Borthakur G, Weisdorf D, Huls G, Perales MA, Valent P, Marcucci G., Free PMC Article | 06/26/2021 |
| A role for CBFbeta in maintaining the metastatic phenotype of breast cancer cells. | A role for CBFβ in maintaining the metastatic phenotype of breast cancer cells.
Ran R, Harrison H, Syamimi Ariffin N, Ayub R, Pegg HJ, Deng W, Mastro A, Ottewell PD, Mason SM, Blyth K, Holen I, Shore P., Free PMC Article | 11/28/2020 |
| Inhibition of Vif-Mediated Degradation of APOBEC3G through Competitive Binding of Core-Binding Factor Beta. | Inhibition of Vif-Mediated Degradation of APOBEC3G through Competitive Binding of Core-Binding Factor Beta.
Miyagi E, Welbourn S, Sukegawa S, Fabryova H, Kao S, Strebel K., Free PMC Article | 09/19/2020 |
| The transcription factor CBFB mutations indicate an improved survival in HR+/HER2- breast cancer. | The transcription factor CBFB mutations indicate an improved survival in HR+/HER2- breast cancer.
Guo L, Chen B, Zhang G, Wang Y, Cao L, Ren C, Wen L, Lin J, Wei G, Liao N. | 09/12/2020 |
| Transcriptional activation of CBFbeta by CDK11(p110) is necessary to promote osteosarcoma cell proliferation | Transcriptional activation of CBFβ by CDK11(p110) is necessary to promote osteosarcoma cell proliferation.
Feng Y, Liao Y, Zhang J, Shen J, Shao Z, Hornicek F, Duan Z., Free PMC Article | 07/18/2020 |
| Type-III IFN-triggered and IL-10-induced CBFbeta are crucial factors for inhibiting Hepatitis B virus (HBV) replication, and the HBx-CBFbeta-HBsAg axis reveals a new molecular mechanism of interaction between HBV and its hosts. | Type III interferon-induced CBFβ inhibits HBV replication by hijacking HBx.
Xu F, Song H, Xiao Q, Li N, Zhang H, Cheng G, Tan G., Free PMC Article | 06/27/2020 |
| Platelet CD34 expression in a patient with a partial deletion of transcription factor subunit CBFB. | Platelet CD34 expression in a patient with a partial deletion of transcription factor subunit CBFB.
van Bergen MGJM, Saes JL, Simons A, Hebeda KM, Henskens YMC, Barteling W, Huys E, Laros-van Gorkom BAP, Schols SEM, Preijers FW, Jongmans MCJ, Jansen JH, van der Reijden BA., Free PMC Article | 06/27/2020 |
| Vif and CBFbeta form a platform to recruit A3F, revealing a direct A3F-recruiting role of CBFbeta beyond Vif stabilization. | Structural basis of antagonism of human APOBEC3F by HIV-1 Vif.
Hu Y, Desimmie BA, Nguyen HC, Ziegler SJ, Cheng TC, Chen J, Wang J, Wang H, Zhang K, Pathak VK, Xiong Y., Free PMC Article | 02/15/2020 |
| CBFB is essential for HIV-1 Vif to arrest host cells at G2/M phase. Vif-CBFB interaction is required for Vif-triggered cell cycle regulation. | Vif-CBFβ interaction is essential for Vif-induced cell cycle arrest.
Du J, Rui Y, Zheng W, Li P, Kang J, Zhao K, Sun T, Yu XF. | 01/18/2020 |
| we identified a novel gastric cancer-associated lncRNA-LINC01234 and first uncover that LINC01234 is an oncogenic lncRNA that promotes cell proliferation and inhibits cell apoptosis through miR-204-5p-CBFB axis in human gastric cancer. | Long Noncoding RNA LINC01234 Functions as a Competing Endogenous RNA to Regulate CBFB Expression by Sponging miR-204-5p in Gastric Cancer.
Chen X, Chen Z, Yu S, Nie F, Yan S, Ma P, Chen Q, Wei C, Fu H, Xu T, Ren S, Sun M, Wang Z. | 12/21/2019 |
| All de novo and relapsed AMLs with CSF3R mutations were associated with genetic alterations in transcription factors, including RUNX1-RUNX1T1, CBFB-MYH11, double-mutated CCAAT/enhancer binding protein alpha (CEBPAdm), and NPM1 mutations; and core-binding factor gene abnormalities and CEBPAdm accounted for 90.5% (19 of 21 patients) | CSF3R Mutations are frequently associated with abnormalities of RUNX1, CBFB, CEBPA, and NPM1 genes in acute myeloid leukemia.
Zhang Y, Wang F, Chen X, Zhang Y, Wang M, Liu H, Cao P, Ma X, Wang T, Zhang J, Zhang X, Lu P, Liu H. | 09/14/2019 |