| Runx3 is required for oncogenic Myc upregulation in p53-deficient osteosarcoma. | Runx3 is required for oncogenic Myc upregulation in p53-deficient osteosarcoma.
Otani S, Date Y, Ueno T, Ito T, Kajikawa S, Omori K, Taniuchi I, Umeda M, Komori T, Toguchida J, Ito K. | 08/28/2024 |
| RUNX3 exerts tumor-suppressive role through inhibiting EXOSC4 expression. | RUNX3 exerts tumor-suppressive role through inhibiting EXOSC4 expression.
Wang N, Miao X, Lu W, Ji Y, Zheng Y, Meng D, Liu H, Xiang C. | 07/11/2024 |
| Downregulation of lncRNA MIR17HG reduced tumorigenicity and Treg-mediated immune escape of non-small-cell lung cancer cells through targeting the miR-17-5p/RUNX3 axis. | Downregulation of lncRNA MIR17HG reduced tumorigenicity and Treg-mediated immune escape of non-small-cell lung cancer cells through targeting the miR-17-5p/RUNX3 axis.
Zheng G, Ye H, Bai J, Zhang X. | 05/30/2024 |
| Ubiquitylation of RUNX3 by RNA-binding ubiquitin ligase MEX3C promotes tumorigenesis in lung adenocarcinoma. | Ubiquitylation of RUNX3 by RNA-binding ubiquitin ligase MEX3C promotes tumorigenesis in lung adenocarcinoma.
He Z, Zhang H, Xiao H, Zhang X, Xu H, Sun R, Li S., Free PMC Article | 03/5/2024 |
| RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription. | RUNX3 inhibits KSHV lytic replication by binding to the viral genome and repressing transcription.
Ren P, Niu D, Chang S, Yu L, Ren J, Ma Y, Lan K., Free PMC Article | 03/4/2024 |
| Differential Runx3, Eomes, and T-bet expression subdivides MS-associated CD4[+] T cells with brain-homing capacity. | Differential Runx3, Eomes, and T-bet expression subdivides MS-associated CD4(+) T cells with brain-homing capacity.
Hoeks C, Puijfelik FV, Koetzier SC, Rip J, Corsten CEA, Wierenga-Wolf AF, Melief MJ, Stinissen P, Smolders J, Hellings N, Broux B, van Luijn MM. | 02/28/2024 |
| Aberrant Upregulation of RUNX3 Activates Developmental Genes to Drive Metastasis in Gastric Cancer. | Aberrant Upregulation of RUNX3 Activates Developmental Genes to Drive Metastasis in Gastric Cancer.
Suda K, Okabe A, Matsuo J, Chuang LSH, Li Y, Jangphattananont N, Mon NN, Myint KN, Yamamura A, So JB, Voon DC, Yang H, Yeoh KG, Kaneda A, Ito Y., Free PMC Article | 02/14/2024 |
| Down-regulation of EZH2 genes targeting RUNX3 affects proliferation, invasion, and metastasis of human colon cancer cells by Wnt/beta-catenin signaling pathway. | Down-regulation of EZH2 genes targeting RUNX3 affects proliferation, invasion, and metastasis of human colon cancer cells by Wnt/β-catenin signaling pathway.
Liang G, Han L, Qu M, Xue J, Xu D, Wu X, Lu Y., Free PMC Article | 12/28/2023 |
| Clinical significance of determining the hypermethylation of the RUNX3 gene promoter and its cohypermethylation with the BRCA1 gene for patients with breast cancer. | Clinical significance of determining the hypermethylation of the RUNX3 gene promoter and its cohypermethylation with the BRCA1 gene for patients with breast cancer.
Rossokha Z, Fishchuk L, Lobanova O, Vershyhora V, Medvedieva N, Cheshuk V, Vereshchako R, Podolska S, Gorovenko N. | 09/1/2023 |
| Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway. | Lemur tyrosine kinase 2 has a tumor-inhibition function in human glioblastoma by regulating the RUNX3/Notch pathway.
Zhang L, Luo P, Mao X, Sun J, Wei J, Yang Y, Zhang Y, Jiang X. | 08/20/2023 |
| Runx1/3-driven adaptive endoplasmic reticulum stress pathways contribute to neurofibromagenesis. | Runx1/3-driven adaptive endoplasmic reticulum stress pathways contribute to neurofibromagenesis.
Na Y, Hall A, Yu Y, Hu L, Choi K, Burgard JA, Szabo S, Huang G, Ratner N, Wu J., Free PMC Article | 08/10/2023 |
| Hsa-miR-301a-3p inhibited the killing effect of natural killer cells on non-small cell lung cancer cells by regulating RUNX3. | Hsa-miR-301a-3p inhibited the killing effect of natural killer cells on non-small cell lung cancer cells by regulating RUNX3.
Zhang J, Yang Y, Wei Y, Li L, Wang X, Ye Z. | 08/9/2023 |
| RUNX3 regulates the susceptibility against EGFR-targeted non-small cell lung cancer therapy using [47]Sc-conjugated cetuximab. | RUNX3 regulates the susceptibility against EGFR-targeted non-small cell lung cancer therapy using (47)Sc-conjugated cetuximab.
Kim DM, Lee SY, Lim JC, Cho EH, Park UJ., Free PMC Article | 07/17/2023 |
| DNA methylation of RUNX3 promotes the progression of gallbladder cancer through repressing SLC7A11-mediated ferroptosis. | DNA methylation of RUNX3 promotes the progression of gallbladder cancer through repressing SLC7A11-mediated ferroptosis.
Cai C, Zhu Y, Mu J, Liu S, Yang Z, Wu Z, Zhao C, Song X, Ye Y, Gu J, Sang Y, Wu X, Gong W. | 06/15/2023 |
| p53 Deficiency-Dependent Oncogenicity of Runx3. | p53 Deficiency-Dependent Oncogenicity of Runx3.
Ito K, Otani S, Date Y., Free PMC Article | 05/23/2023 |
| RUNX3 Meets the Ubiquitin-Proteasome System in Cancer. | RUNX3 Meets the Ubiquitin-Proteasome System in Cancer.
Toska A, Modi N, Chen LF., Free PMC Article | 03/14/2023 |
| Role of RUNX3 in Restriction Point Regulation. | Role of RUNX3 in Restriction Point Regulation.
Lee JW, Lee YS, Kim MK, Chi XZ, Kim D, Bae SC., Free PMC Article | 03/14/2023 |
| Genetically encoded Runx3 and CD4[+] intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy. | Genetically encoded Runx3 and CD4(+) intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy.
Bhuyan ZA, Rahman MA, Maradana MR, Mehdi AM, Bergot AS, Simone D, El-Kurdi M, Garrido-Mesa J, Cai CBB, Cameron AJ, Hanson AL, Nel HJ, Kenna T, Leo P, Rehaume L, Brown MA, Ciccia F, Thomas R. | 02/22/2023 |
| Increased transcription of hsa_circ_0000644 upon RUNX family transcription factor 3 downregulation participates in the malignant development of bladder cancer. | Increased transcription of hsa_circ_0000644 upon RUNX family transcription factor 3 downregulation participates in the malignant development of bladder cancer.
Zhou H, Huang J, Wang F. | 02/15/2023 |
| RUNX3 in Stem Cell and Cancer Biology. | RUNX3 in Stem Cell and Cancer Biology.
Chuang LSH, Matsuo J, Douchi D, Bte Mawan NA, Ito Y., Free PMC Article | 02/15/2023 |
| MicroRNA-20a-5p regulates the epithelial-mesenchymal transition of human hepatocellular carcinoma by targeting RUNX3. | MicroRNA-20a-5p regulates the epithelial-mesenchymal transition of human hepatocellular carcinoma by targeting RUNX3.
Wang X, Wei P, Yang L, Liu F, Tong X, Yang X, Su L., Free PMC Article | 12/10/2022 |
| Methylation of RUNX3 Promoter 2 in the Whole Blood of Children with Ulcerative Colitis. | Methylation of RUNX3 Promoter 2 in the Whole Blood of Children with Ulcerative Colitis.
Dybska E, Nowak JK, Banaszkiewicz A, Szaflarska-Popławska A, Kierkuś J, Kwiecień J, Grzybowska-Chlebowczyk U, Walkowiak J., Free PMC Article | 10/8/2022 |
| Integrated Analysis of the Expression, Involved Functions, and Regulatory Network of RUNX3 in Melanoma. | Integrated Analysis of the Expression, Involved Functions, and Regulatory Network of RUNX3 in Melanoma.
Feng Z, Liu Y, Chen H. | 08/27/2022 |
| Increased expression of RUNX3 inhibits normal human myeloid development. | Increased expression of RUNX3 inhibits normal human myeloid development.
Menezes AC, Jones R, Shrestha A, Nicholson R, Leckenby A, Azevedo A, Davies S, Baker S, Gilkes AF, Darley RL, Tonks A., Free PMC Article | 07/16/2022 |
| YBX1 regulated by Runx3-miR-148a-3p axis facilitates non-small-cell lung cancer progression. | YBX1 regulated by Runx3-miR-148a-3p axis facilitates non-small-cell lung cancer progression.
Su H, Fan G, Huang J, Qiu X. | 07/16/2022 |