| The TDP-43/TP63 Positive Feedback Circuit Promotes Esophageal Squamous Cell Carcinoma Progression. | The TDP-43/TP63 Positive Feedback Circuit Promotes Esophageal Squamous Cell Carcinoma Progression.
Li W, Yang Y, Huang L, Yu X, Wang T, Zhang N, Yang M., Free PMC Article | 10/3/2024 |
| Interaction between MED12 and DeltaNp63 activates basal identity in pancreatic ductal adenocarcinoma. | Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma.
Maia-Silva D, Cunniff PJ, Schier AC, Skopelitis D, Trousdell MC, Moresco P, Gao Y, Kechejian V, He XY, Sahin Y, Wan L, Alpsoy A, Liverpool J, Krainer AR, Egeblad M, Spector DL, Fearon DT, Dos Santos CO, Taatjes DJ, Vakoc CR., | 08/13/2024 |
| DeltaNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma. | ΔNp63-restricted viral mimicry response impedes cancer cell viability and remodels tumor microenvironment in esophageal squamous cell carcinoma.
Yu VZ, So SS, Lung BC, Hou GZ, Wong CW, Chow LK, Chung MK, Wong IY, Wong CL, Chan DK, Chan FS, Law BT, Xu K, Tan ZZ, Lam KO, Lo AW, Lam AK, Kwong DL, Ko JM, Dai W, Law S, Lung ML. | 07/15/2024 |
| Distinct Effects of Respiratory Viral Infection Models on miR-149-5p, IL-6 and p63 Expression in BEAS-2B and A549 Epithelial Cells. | Distinct Effects of Respiratory Viral Infection Models on miR-149-5p, IL-6 and p63 Expression in BEAS-2B and A549 Epithelial Cells.
Shahdab N, Ward C, Hansbro PM, Cummings S, Young JS, Moheimani F., Free PMC Article | 07/3/2024 |
| Identification of HTRA4 as a Transcriptional Target of p63 in Trophoblast. | Identification of HTRA4 as a Transcriptional Target of p63 in Trophoblast.
Donohoe ME, Morey R, Li Y, Pizzo D, Kallol S, Cho HY, Soncin F, Parast MM., | 07/1/2024 |
| TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2. | TP63 truncating mutation causes increased cell apoptosis and premature ovarian insufficiency by enhanced transcriptional activation of CLCA2.
Fan Y, Chen S, Chu C, Yin X, Jin J, Zhang L, Yan H, Cao Z, Liu R, Xin M, Li L, Yin C., Free PMC Article | 04/5/2024 |
| Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-gamma signaling in squamous cancer. | Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer.
Jiang Y, Zheng Y, Zhang YW, Kong S, Dong J, Wang F, Ziman B, Gery S, Hao JJ, Zhou D, Zhou J, Ho AS, Sinha UK, Chen J, Zhang S, Yin C, Wei DD, Hazawa M, Pan H, Lu Z, Wei WQ, Wang MR, Koeffler HP, Lin DC, Jiang YY., Free PMC Article | 03/22/2024 |
| A spectrum of TP63-related disorders with eight affected individuals in five unrelated families. | A spectrum of TP63-related disorders with eight affected individuals in five unrelated families.
Soğukpınar M, Utine GE, Boduroğlu K, Şimşek-Kiper PÖ. | 03/20/2024 |
| Tumour 63 protein (p63) in breast pathology: biology, immunohistochemistry, diagnostic applications, and pitfalls. | Tumour 63 protein (p63) in breast pathology: biology, immunohistochemistry, diagnostic applications, and pitfalls.
Alkhayyat R, Abbas A, Quinn CM, Rakha EA. | 03/12/2024 |
| Absent meibomian glands and cone dystrophy in ADULT syndrome: identification by whole exome sequencing of pathogenic variants in two causal genes TP63 and CNGB3. | Absent meibomian glands and cone dystrophy in ADULT syndrome: identification by whole exome sequencing of pathogenic variants in two causal genes TP63 and CNGB3.
Hizem S, Maamouri R, Zaouak A, Rejeb I, Karoui S, Sebai M, Jilani H, Elaribi Y, Fenniche S, Cheour M, Bilan F, Ben Jemaa L. | 02/6/2024 |
| Association between IRF6, TP63, GREM1 Gene Polymorphisms and Non-Syndromic Orofacial Cleft Phenotypes in Vietnamese Population: A Case-Control and Family-Based Study. | Association between IRF6, TP63, GREM1 Gene Polymorphisms and Non-Syndromic Orofacial Cleft Phenotypes in Vietnamese Population: A Case-Control and Family-Based Study.
Pham LNG, Niimi T, Suzuki S, Nguyen MD, Nguyen LCH, Nguyen TD, Hoang KA, Nguyen DM, Sakuma C, Hayakawa T, Hiyori M, Natsume N, Furukawa H, Imura H, Akashi J, Ohta T, Natsume N., Free PMC Article | 11/27/2023 |
| p63: a crucial player in epithelial stemness regulation. | p63: a crucial player in epithelial stemness regulation.
Li Y, Giovannini S, Wang T, Fang J, Li P, Shao C, Wang Y, TOR centre, Shi Y, Candi E, Melino G, Bernassola F., Free PMC Article | 11/14/2023 |
| Effects of TP63 mutations on keratinocyte adhesion and migration. | Effects of TP63 mutations on keratinocyte adhesion and migration.
Salois MN, Gugger JA, Webb S, Sheldon CE, Parraga SP, Lewitt GM, Grange DK, Koch PJ, Koster MI., Free PMC Article | 11/1/2023 |
| Transcription factor TP63 mediates LncRNA CNTFR-AS1 to promote DNA damage induced by neodymium oxide nanoparticles via homologous recombination repair. | Transcription factor TP63 mediates LncRNA CNTFR-AS1 to promote DNA damage induced by neodymium oxide nanoparticles via homologous recombination repair.
Gao L, Zhang X, Cui J, Liu L, Tai D, Wang S, Huang L. | 11/1/2023 |
| Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation. | Stepwise activation of p63 and the MEK/ERK pathway induces the expression of ARL4C to promote oral squamous cell carcinoma cell proliferation.
Alkhatib DZR, Thi Kim Truong T, Fujii S, Hasegawa K, Nagano R, Tajiri Y, Kiyoshima T. | 10/28/2023 |
| DeltaNp63 overexpression promotes oral cancer cell migration through hyperactivated Activin A signaling. | ΔNp63 overexpression promotes oral cancer cell migration through hyperactivated Activin A signaling.
Mundhe D, Mishra R, Basu S, Dalal S, Kumar S, Teni T. | 09/11/2023 |
| Heterozygous TP63 pathogenic variants in isolated primary ovarian insufficiency. | Heterozygous TP63 pathogenic variants in isolated primary ovarian insufficiency.
Vanderschelden RK, Rodriguez-Escriba M, Chan SH, Berman AJ, Rajkovic A, Yatsenko SA., Free PMC Article | 08/25/2023 |
| A robust gene prognostic index composed of GZMB, IRF1, and TP63 can stratify the risk of two metastatic urothelial carcinoma cohorts based on immune checkpoint blockade therapy. | A robust gene prognostic index composed of GZMB, IRF1, and TP63 can stratify the risk of two metastatic urothelial carcinoma cohorts based on immune checkpoint blockade therapy.
Lin J, Ding M, Qin C, Song Y, Yang W, Du Y, Xu T. | 08/20/2023 |
| A novel de novo TP63 mutation in whole-exome sequencing of a Syrian family with Oral cleft and ectrodactyly. | A novel de novo TP63 mutation in whole-exome sequencing of a Syrian family with Oral cleft and ectrodactyly.
Simpson CL, Kimble DC, Chandrasekharappa SC, NISC Comparative Sequencing Program, Alqosayer K, Holzinger E, Carrington B, McElderry J, Sood R, Al-Souqi G, Albacha-Hejazi H, Bailey-Wilson JE., Free PMC Article | 08/14/2023 |
| Genetic analysis of polymorphism rs10937405 of TP63 gene in breast and ovarian cancer patients of North Indian Cohort. | Genetic analysis of polymorphism rs10937405 of TP63 gene in breast and ovarian cancer patients of North Indian Cohort.
Verma S, Bakshi D, Bhat GR, Bhat A, Shah R, Sharma B, Wakhloo A, Heer V, Chander G, Kumar R. | 08/10/2023 |
| The Splicing Factor PTBP1 Represses TP63 gamma Isoform Production in Squamous Cell Carcinoma. | The Splicing Factor PTBP1 Represses TP63 γ Isoform Production in Squamous Cell Carcinoma.
Taylor W, Deschamps S, Reboutier D, Paillard L, Méreau A, Audic Y., Free PMC Article | 08/1/2023 |
| Transcription factors TP63 facilitates malignant progression of thyroid cancer by upregulating KRT17 expression and inducing epithelial-mesenchymal transition. | Transcription factors TP63 facilitates malignant progression of thyroid cancer by upregulating KRT17 expression and inducing epithelial-mesenchymal transition.
Meng F, Dai L. | 07/6/2023 |
| A TP63 mutation identified in a Han Chinese family with ectodermal dysplasia. | A TP63 mutation identified in a Han Chinese family with ectodermal dysplasia.
Zhou X, Zhang C, Fan L, Wu S, Yao S, Wang L, Zhong W, Ma L, Pan Y. | 06/19/2023 |
| Disease-related p63 DBD mutations impair DNA binding by distinct mechanisms and varying degree. | Disease-related p63 DBD mutations impair DNA binding by distinct mechanisms and varying degree.
Osterburg C, Ferniani M, Antonini D, Frombach AS, D'Auria L, Osterburg S, Lotz R, Löhr F, Kehrloesser S, Zhou H, Missero C, Dötsch V., Free PMC Article | 05/19/2023 |
| Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression. | Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression.
Ning B, Tilston-Lunel AM, Simonetti J, Hicks-Berthet J, Matschulat A, Pfefferkorn R, Spira A, Edwards M, Mazzilli S, Lenburg ME, Beane JE, Varelas X., Free PMC Article | 05/15/2023 |