MicroRNA-101-3p inhibits nasopharyngeal carcinoma cell proliferation and cisplatin resistance through ZIC5 down-regulation by targeting SOX2. | MicroRNA-101-3p inhibits nasopharyngeal carcinoma cell proliferation and cisplatin resistance through ZIC5 down-regulation by targeting SOX2. Li T, Zhang G, Li W, Xiao J, Zhou Z, Tan G, Ai J. | 09/19/2023 |
LINC01116 Regulates the Proliferation and Apoptosis of Nucleus Pulposus Cells through miR-9-5p-mediated ZIC5 and the Wnt Pathway and Affects the Progression of Intervertebral Disc Degeneration. | LINC01116 Regulates the Proliferation and Apoptosis of Nucleus Pulposus Cells through miR-9-5p-mediated ZIC5 and the Wnt Pathway and Affects the Progression of Intervertebral Disc Degeneration. Xu S, Li Y, Zhang J, Li Z. | 06/5/2023 |
ZIC5 promotes aggressiveness and cancer stemness in cervical squamous cell carcinoma. | ZIC5 promotes aggressiveness and cancer stemness in cervical squamous cell carcinoma. Jia Q, Song J, Xu T, Liu J, Chai J, Yang Y, Li L, Li M, Yang X. | 01/28/2023 |
Transcriptional expression of ZICs as an independent indicator of survival in gliomas. | Transcriptional expression of ZICs as an independent indicator of survival in gliomas. Han Z, Jia J, Lv Y, Wang R, Cao K., Free PMC Article | 12/25/2021 |
SP1-mediated upregulation of lncRNA SNHG4 functions as a ceRNA for miR-377 to facilitate prostate cancer progression through regulation of ZIC5. | SP1-mediated upregulation of lncRNA SNHG4 functions as a ceRNA for miR-377 to facilitate prostate cancer progression through regulation of ZIC5. Wang ZY, Duan Y, Wang P. | 02/6/2021 |
Interfering Wnt/-catenin-Zic5 axis-regulated aerobic glycolysis represents a potentially effective strategy to selectively target colon cancer cells. | β-Catenin/Tcf7l2-dependent transcriptional regulation of GLUT1 gene expression by Zic family proteins in colon cancer. Zhao Z, Wang L, Bartom E, Marshall S, Rendleman E, Ryan C, Shilati A, Savas J, Chandel N, Shilatifard A., Free PMC Article | 05/16/2020 |
The study reveals a novel mechanism of ZIC5/beta-catenin that mediates the invasion and metastasis of HCC and ZIC5 serves as a novel indicator for prognosis of hepatocellular carcinoma (HCC) patients. | ZIC5 facilitates the growth of hepatocellular carcinoma through activating Wnt/β-catenin pathway. Liu L, Hu X, Sun D, Wu Y, Zhao Z. | 05/18/2019 |
hsa_circ_0007534 serves as an oncogene in glioma via promoting ZIC5 expression by repressing miR-761 availability. | Hsa_circ_0007534/miR-761/ZIC5 regulatory loop modulates the proliferation and migration of glioma cells. Li GF, Li L, Yao ZQ, Zhuang SJ. | 10/13/2018 |
ZIC5 positively regulated the proliferation, migration, and survival of prostate colorectal cancer cells | Identification of zinc finger protein of the cerebellum 5 as a survival factor of prostate and colorectal cancer cells. Satow R, Inagaki S, Kato C, Shimozawa M, Fukami K., Free PMC Article | 12/16/2017 |
ZIC5 is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene by influencing CCNB1 and CDK1 complex expression | Overexpression of ZIC5 promotes proliferation in non-small cell lung cancer. Sun Q, Shi R, Wang X, Li D, Wu H, Ren B. | 06/3/2017 |
ZIC1, ZIC2, and ZIC5 may have roles in meningiomas | Expression of ZIC family genes in meningiomas and other brain tumors. Aruga J, Nozaki Y, Hatayama M, Odaka YS, Yokota N., Free PMC Article | 01/1/2011 |
the smallest 13q deletion associated to DWM allows further narrowing of the previously established critical region for this brain malformation to 13q32.2-32.3. Among the few genes of the deleted region, ZIC2 and ZIC5 seem the most plausible candidates. | Description of the smallest critical region for Dandy-Walker malformation in chromosome 13 in a girl with a cryptic deletion related to t(6;13)(q23;q32). Mademont-Soler I, Morales C, Armengol L, Soler A, Sánchez A. | 01/1/2011 |