| On the regulation of human D-aspartate oxidase. | On the regulation of human D-aspartate oxidase.
Rabattoni V, Motta Z, Miceli M, Molla G, Fissore A, Adinolfi S, Pollegioni L, Sacchi S., Free PMC Article | 10/30/2023 |
| Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival. | Genetic variants in DDO and PEX5L in peroxisome-related pathways predict non-small cell lung cancer survival.
Chen AS, Liu H, Wu Y, Luo S, Patz EF Jr, Glass C, Su L, Du M, Christiani DC, Wei Q. | 08/27/2022 |
| D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans. | D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans.
Lombardo B, Pagani M, De Rosa A, Nunziato M, Migliarini S, Garofalo M, Terrile M, D'Argenio V, Galbusera A, Nuzzo T, Ranieri A, Vitale A, Leggiero E, Di Maio A, Barsotti N, Borello U, Napolitano F, Mandarino A, Carotenuto M, Heresco-Levy U, Pasqualetti M, Malatesta P, Gozzi A, Errico F, Salvatore F, Pastore L, Usiello A., Free PMC Article | 08/6/2022 |
| Cellular studies of the two main isoforms of human d-aspartate oxidase. | Cellular studies of the two main isoforms of human d-aspartate oxidase.
Rabattoni V, Pollegioni L, Tedeschi G, Maffioli E, Sacchi S. | 09/11/2021 |
| three-dimensional structural analysis contributes insights into the structure-function relationships of human DASPO | Structure and kinetic properties of human d-aspartate oxidase, the enzyme-controlling d-aspartate levels in brain.
Molla G, Chaves-Sanjuan A, Savinelli A, Nardini M, Pollegioni L. | 07/25/2020 |
| The strongest DNA methylation changes in atopic asthma were detected in the promoter region of SMAD3 gene at chr 15q22.33 and introns of DDO/METTL24 genes at 6q21. | Atopic asthma after rhinovirus-induced wheezing is associated with DNA methylation change in the SMAD3 gene promoter.
Lund RJ, Osmala M, Malonzo M, Lukkarinen M, Leino A, Salmi J, Vuorikoski S, Turunen R, Vuorinen T, Akdis C, Lähdesmäki H, Lahesmaa R, Jartti T., Free PMC Article | 11/2/2019 |
| This study is the first to report robust age associations for DNA methylation in MYOF and DDO, both of which have plausible functional roles in aging | Methylome-wide association study of whole blood DNA in the Norfolk Island isolate identifies robust loci associated with age.
Benton MC, Sutherland HG, Macartney-Coxson D, Haupt LM, Lea RA, Griffiths LR., Free PMC Article | 11/18/2017 |
| SNPSs R216Q and S308N reduce enzyme activity towards acidic d-amino acids, decrease the binding affinity for the coenzyme flavin adenine dinucleotide and decrease the temperature stability. Expression of DDO genes carrying the R216Q or S308N SNP substitutions may increase the d-aspartate content in humans and alter homeostasis of several other amino acids. | Structure-function relationships in human d-aspartate oxidase: characterisation of variants corresponding to known single nucleotide polymorphisms.
Katane M, Kanazawa R, Kobayashi R, Oishi M, Nakayama K, Saitoh Y, Miyamoto T, Sekine M, Homma H. | 10/28/2017 |
| Characterization of the enzymatic and structural properties of human D-aspartate oxidase and comparison with those of the rat and mouse enzymes | Characterization of the enzymatic and structural properties of human D-aspartate oxidase and comparison with those of the rat and mouse enzymes.
Katane M, Kawata T, Nakayama K, Saitoh Y, Kaneko Y, Matsuda S, Saitoh Y, Miyamoto T, Sekine M, Homma H. | 12/19/2015 |
| There is a significant increase in DDO mRNA expression in the prefrontal cortex of patients with schizophrenia compared to controls. | A role for D-aspartate oxidase in schizophrenia and in schizophrenia-related symptoms induced by phencyclidine in mice.
Errico F, D'Argenio V, Sforazzini F, Iasevoli F, Squillace M, Guerri G, Napolitano F, Angrisano T, Di Maio A, Keller S, Vitucci D, Galbusera A, Chiariotti L, Bertolino A, de Bartolomeis A, Salvatore F, Gozzi A, Usiello A., Free PMC Article | 09/12/2015 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Human variation in alcohol response is influenced by variation in neuronal signaling genes.
Joslyn G, Ravindranathan A, Brush G, Schuckit M, White RL. | 04/7/2010 |
| data do not suggest that DDO plays a role in the etiology of schizophrenia in the German population | No association between the D-aspartate oxidase locus and schizophrenia.
Jamra RA, Georgi A, Suliman H, Klein K, Villela AW, Schulze TG, Propping P, Cichon S, Rietschel M, Nöthen MM, Schumacher J. | 01/21/2010 |