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    Abcg1 ATP binding cassette subfamily G member 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 85264, updated on 17-Aug-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Decreased expression of ATP-binding cassette protein G1 promotes abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis.

    Decreased expression of ATP-binding cassette protein G1 promotes abnormal adipogenesis of condylar chondrocytes in temporomandibular joint osteoarthritis.
    Kang X, Liu Q, Shi Y, Wang H, Zhang H, Ye T, Zhang J, He F, Zhang M.

    04/15/2024
    Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats.

    Deregulation of ABCG1 early in life contributes to prostate carcinogenesis in maternally malnourished offspring rats.
    Camargo AC, Constantino FB, Santos SA, Colombelli KT, Portela LM, Fioretto MN, Barata LA, Valente GT, Moreno CS, Justulin LA.

    01/3/2024
    ABCG1 and ABCG4 as key transporters in the development of pulmonary alveolar proteinosis by nanoparticles.

    ABCG1 and ABCG4 as key transporters in the development of pulmonary alveolar proteinosis by nanoparticles.
    Jeon S, Kim SH, Jeong J, Lee DK, Lee S, Kim S, Kim G, Maruthupandy M, Cho WS.

    10/30/2021
    The addition of U0126 resulted in a marked reduction of lipid deposition, upregulation of ABCA1/G1 expression and suppression of CD36 expression in Ox-LDL-stimulated macrophages.

    Inhibition of ERK1/2 improves lipid balance in rat macrophages via ABCA1/G1 and CD36.
    Xue XH, Shi FF, Chen T, Wei W, Zhou XM, Chen LD.

    10/29/2016
    ABCA1 is diminished and ABCG1 is increased by N-acetylcysteine, which counteracts the reduction in apo A-I-mediated cholesterol efflux

    N-acetylcysteine prevents endoplasmic reticulum stress elicited in macrophages by serum albumin drawn from chronic kidney disease rats and selectively affects lipid transporters, ABCA-1 and ABCG-1.
    Machado JT, Iborra RT, Fusco FB, Castilho G, Pinto RS, Machado-Lima A, Nakandakare ER, Seguro AC, Shimizu MH, Catanozi S, Passarelli M.

    08/22/2015
    ABCG1 is involved in cellular vitamin E efflux.

    ABCG1 is involved in vitamin E efflux.
    Olivier M, BottG R, Frisdal E, Nowick M, Plengpanich W, Desmarchelier C, Roi S, Quinn CM, Gelissen I, Jessup W, Van Eck M, Guérin M, Le Goff W, Reboul E.

    04/18/2015
    enriched in chronic inflammation of the small intestine of type 2 diabetic rats

    ABCA1 and ABCG1 expression in the small intestine of type 2 diabetic rats.
    Lou J, Zhou H, Li C, Hu L, Lu X, Li J, Yao H, Li W, Zhang X, Xu M.

    05/24/2014
    In macrophages under oxidative stress (by overloading with oxidized LDL), down-regulation of ABCG-1 and ABCA-1 is key to regulation of metabolism of 7-ketocholesterol and other sterols.

    Advanced glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1.
    Iborra RT, Machado-Lima A, Castilho G, Nunes VS, Abdalla DS, Nakandakare ER, Passarelli M., Free PMC Article

    01/28/2012
    Endothelin-1 markedly decreased ABCG1 levels via endothelin type A and B receptors and activation of the phosphatidylinositol 3-kinase pathway. Endothelin-1 may have also enhanced ABCG1's degradation.

    Endothelin-1 exacerbates lipid accumulation by increasing the protein degradation of the ATP-binding cassette transporter G1 in macrophages.
    Lin CY, Lee TS, Chen CC, Chang CA, Lin YJ, Hsu YP, Ho LT.

    07/30/2011
    LpE and LRP1 promote axonal extension, and suggest that lipids exported to LpE by ABCG1 are important for the enhancement of axonal extension mediated by LpE.

    Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins.
    Matsuo M, Campenot RB, Vance DE, Ueda K, Vance JE.

    02/26/2011
    Data show that niacin therapyreduced renal tissue lipids, CD36, ChREBP, LXR, ABCA-1, ABCG-1, and SR-B1 abundance and raised PPAR-alpha and L-FABP.

    Niacin improves renal lipid metabolism and slows progression in chronic kidney disease.
    Cho KH, Kim HJ, Kamanna VS, Vaziri ND.

    04/12/2010
    Results show that scavenger receptor-BI, ATP-binding cassette A1 and G1 mRNA expression increased in response to dexamethasone while insulin treatment reduced the expression in primary rat hepatocytes.

    ABCA1, ABCG1 and SR-BI: hormonal regulation in primary rat hepatocytes and human cell lines.
    Sporstøl M, Mousavi SA, Eskild W, Roos N, Berg T., Free PMC Article

    01/21/2010
    Protein and mRNA expression of the ATP-binding cassette transporter G1 (ABCG1) was markedly higher in tumors than in livers.

    Hypercholesterolemia in rats with hepatomas: increased oxysterols accelerate efflux but do not inhibit biosynthesis of cholesterol.
    Hirayama T, Honda A, Matsuzaki Y, Miyazaki T, Ikegami T, Doy M, Xu G, Lea M, Salen G.

    01/21/2010
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