| An interaction between beta'-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling. | An interaction between β'-COP and the ArfGAP, Glo3, maintains post-Golgi cargo recycling.
Xie B, Guillem C, Date SS, Cohen CI, Jung C, Kendall AK, Best JT, Graham TR, Jackson LP., Free PMC Article | 02/24/2023 |
| Structural basis for activation of Arf1 at the Golgi complex. | Structural basis for activation of Arf1 at the Golgi complex.
Muccini AJ, Gustafson MA, Fromme JC., Free PMC Article | 09/24/2022 |
| The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus. | The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.
Kolakowski D, Rzepnikowska W, Kaniak-Golik A, Zoladek T, Kaminska J., Free PMC Article | 12/25/2021 |
| Arf1 directly recruits the Pik1-Frq1 PI4K complex to regulate the final stages of Golgi maturation. | Arf1 directly recruits the Pik1-Frq1 PI4K complex to regulate the final stages of Golgi maturation.
Highland CM, Fromme JC., Free PMC Article | 12/11/2021 |
| Arf1 orchestrates Rab GTPase conversion at the trans-Golgi network. | Arf1 orchestrates Rab GTPase conversion at the trans-Golgi network.
Thomas LL, Highland CM, Fromme JC., Free PMC Article | 12/4/2021 |
| The Glo3 GAP crystal structure supports the molecular niche model for ArfGAPs in COPI coats. | The Glo3 GAP crystal structure supports the molecular niche model for ArfGAPs in COPI coats.
Xie B, Jung C, Chandra M, Engel A, Kendall AK, Jackson LP., Free PMC Article | 10/30/2021 |
| Date show that ADP-ribosylation factor 1 (ARF1) deletion alters Vps74 distribution along Golgi stacks. | Vps74p controls Golgi size in an Arf1-dependent manner.
Iyer P, Bhave M, Jain BK, RoyChowdhury S, Bhattacharyya D. | 06/15/2019 |
| Arf1 and the exomer cargo adaptor coordinate cargo sorting into subset of secretory vesicle carriers in the model organism Saccharomyces cerevisiae. Here, we detail the assays we used to explore the cooperative action of Arf1 and exomer to bind and remodel membranes. | Analysis of Arf1 GTPase-Dependent Membrane Binding and Remodeling Using the Exomer Secretory Vesicle Cargo Adaptor.
Paczkowski JE, Fromme JC., Free PMC Article | 01/6/2018 |
| The DCB/HUS domain amplifies the ability of Sec7 to activate Arf1 on the membrane surface by facilitating membrane insertion of the Arf1 amphipathic helix. | The Sec7 N-terminal regulatory domains facilitate membrane-proximal activation of the Arf1 GTPase.
Richardson BC, Halaby SL, Gustafson MA, Fromme JC., Free PMC Article | 01/14/2017 |
| Arf1 is involved in mitochondrial homeostasis and dynamics, independent of its role in vesicular traffic. | The small GTPase Arf1 modulates mitochondrial morphology and function.
Ackema KB, Hench J, Böckler S, Wang SC, Sauder U, Mergentaler H, Westermann B, Bard F, Frank S, Spang A., Free PMC Article | 02/14/2015 |
| Study demonstrates V-ATPase interacts with two distinct GTPases, Arf1 and Gtr1, which are required for Ras and TORC1 activation, respectively. | Cytosolic pH regulates cell growth through distinct GTPases, Arf1 and Gtr1, to promote Ras/PKA and TORC1 activity.
Dechant R, Saad S, Ibáñez AJ, Peter M. | 10/18/2014 |
| Study determined the structure of Arf1 bound to the gammazeta-COP subcomplex of coatomer; and finds that betadelta/gammazeta-COP interacts with two molecules of Arf1-GTP, which bind to quasi-equivalent sites on the large beta-COP and gamma-COP subunits. | A structure-based mechanism for Arf1-dependent recruitment of coatomer to membranes.
Yu X, Breitman M, Goldberg J., Free PMC Article | 03/24/2012 |
| nucleosome shielding is the primary means to maintain promoter fidelity, and histone replacement is most efficiently mediated in yeast cells by a HIR/Asf1/H3-H4/Rtt106 pathway. | The replication-independent histone H3-H4 chaperones HIR, ASF1, and RTT106 co-operate to maintain promoter fidelity.
Silva AC, Xu X, Kim HS, Fillingham J, Kislinger T, Mennella TA, Keogh MC., Free PMC Article | 03/10/2012 |
| Here we demonstrate that Trs65p directly binds to the C-terminus of the Arf1p exchange factor Gea2p and provide in vivo evidence that this interaction is physiologically relevant | Trs65p, a subunit of the Ypt1p GEF TRAPPII, interacts with the Arf1p exchange factor Gea2p to facilitate COPI-mediated vesicle traffic.
Chen S, Cai H, Park SK, Menon S, Jackson CL, Ferro-Novick S., Free PMC Article | 02/11/2012 |
| COPI in these mutants is released from Golgi membranes by brefeldin A, a drug that binds directly to guanine nucleotide exchange factor for ADP ribosylation factors and blocks Arf1 activation | Mutations in a highly conserved region of the Arf1p activator GEA2 block anterograde Golgi transport but not COPI recruitment to membranes.
Park SK, Hartnell LM, Jackson CL., Free PMC Article | 01/21/2010 |
| ScARF1 and ScARF3 are the yeast orthologs of mammalian ARF1 and ARF6 and have roles in the control of peroxisome proliferation | Binding and functions of ADP-ribosylation factor on mammalian and yeast peroxisomes.
Lay D, L Grosshans B, Heid H, Gorgas K, Just WW. | 01/21/2010 |
| Arf1p has a role in linking COPI vesicles and mRNA in Saccharomyces cerevisiae | Arf1p provides an unexpected link between COPI vesicles and mRNA in Saccharomyces cerevisiae.
Trautwein M, Dengjel J, Schirle M, Spang A., Free PMC Article | 01/21/2010 |
| Arf1p and Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi | The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi.
Gillingham AK, Tong AH, Boone C, Munro S., Free PMC Article | 01/21/2010 |