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    MIR503HG MIR503 host gene [ Homo sapiens (human) ]

    Gene ID: 84848, updated on 17-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    LINC MIR503HG Controls SC-beta Cell Differentiation and Insulin Production by Targeting CDH1 and HES1.

    LINC MIR503HG Controls SC-β Cell Differentiation and Insulin Production by Targeting CDH1 and HES1.
    Xu Y, Mao S, Fan H, Wan J, Wang L, Zhang M, Zhu S, Yuan J, Lu Y, Wang Z, Yu B, Jiang Z, Huang Y., Free PMC Article

    04/15/2024
    Loss of MIR503HG facilitates papillary renal cell carcinoma associated lymphatic metastasis by triggering NOTCH1/VEGFC signaling.

    Loss of MIR503HG facilitates papillary renal cell carcinoma associated lymphatic metastasis by triggering NOTCH1/VEGFC signaling.
    Wang Y, Zheng X, Huang W, Lu J, Hou N, Qi J, Ma J, Xue W, Zheng J, Zhai W., Free PMC Article

    07/12/2023
    lncRNA MIR503HG Targets miR-191-5p/PLCD1 Axis and Negatively Modulates Apoptosis, Extracellular Matrix Disruption, and Inflammation in Abdominal Aortic Aneurysm.

    lncRNA MIR503HG Targets miR-191-5p/PLCD1 Axis and Negatively Modulates Apoptosis, Extracellular Matrix Disruption, and Inflammation in Abdominal Aortic Aneurysm.
    Tian Y, Li X, Bai C, Yang Z, Zhang L, Luo J, Zhang W., Free PMC Article

    06/12/2023
    MIR503HG: A potential diagnostic and therapeutic target in human diseases.

    MIR503HG: A potential diagnostic and therapeutic target in human diseases.
    Han X, Li B, Zhang S.

    03/8/2023
    [MIR503HG promotes esophageal squamous cell carcinoma cell proliferation, invasion and migration via hsa-miR-503 pathway].

    [MIR503HG promotes esophageal squamous cell carcinoma cell proliferation, invasion and migration via hsa-miR-503 pathway].
    Gong TY, Chen HY, Liu ZH.

    12/10/2022
    MIR503HG impeded ovarian cancer progression by interacting with SPI1 and preventing TMEFF1 transcription.

    MIR503HG impeded ovarian cancer progression by interacting with SPI1 and preventing TMEFF1 transcription.
    Tian J, Yang L, Wang Z, Yan H., Free PMC Article

    07/30/2022
    Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-kappaB/NLRP3 Inflammasome Pathway.

    Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway.
    Wang Y, Liu F, Chen L, Fang C, Li S, Yuan S, Qian X, Yin Y, Yu B, Fu B, Zhang X, Li Y., Free PMC Article

    06/25/2022
    Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing.

    Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing.
    Li X, He Z, Zhang J, Han Y., Free PMC Article

    02/19/2022
    LncRNA MIR503HG promotes hypertrophic scar progression via miR-143-3p-mediated Smad3 expression.

    LncRNA MIR503HG promotes hypertrophic scar progression via miR-143-3p-mediated Smad3 expression.
    Wei J, Wang Z, Zhong C, Ding H, Wang X, Lu S.

    02/5/2022
    MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease.

    MIR503HG Loss Promotes Endothelial-to-Mesenchymal Transition in Vascular Disease.
    Monteiro JP, Rodor J, Caudrillier A, Scanlon JP, Spiroski AM, Dudnakova T, Pflüger-Müller B, Shmakova A, von Kriegsheim A, Deng L, Taylor RS, Wilson-Kanamori JR, Chen SH, Stewart K, Thomson A, Mitić T, McClure JD, Iynikkel J, Hadoke PWF, Denby L, Bradshaw AC, Caruso P, Morrell NW, Kovacic JC, Ulitsky I, Henderson NC, Caporali A, Leisegang MS, Brandes RP, Baker AH., Free PMC Article

    01/8/2022
    LncRNA MIR503HG regulated cell viability, metastasis and apoptosis of cervical cancer via miR-191/CEBPB axis.

    LncRNA MIR503HG regulated cell viability, metastasis and apoptosis of cervical cancer via miR-191/CEBPB axis.
    Hu YL, Zhang YX, Liu N, Liu H, Yuan YC.

    01/8/2022
    MiR-503-5p functions as an oncogene in oral squamous cell carcinoma by targeting Smad7.

    MiR-503-5p functions as an oncogene in oral squamous cell carcinoma by targeting Smad7.
    Fei Y, Shan W, Chen X.

    07/10/2021
    Structure and expression of the long noncoding RNA gene MIR503 in humans and non-human primates.

    Structure and expression of the long noncoding RNA gene MIR503 in humans and non-human primates.
    Choudhari R, Yang B, Rotwein P, Gadad SS.

    05/29/2021
    Long non-coding RNA MIR503HG inhibits the proliferation, migration and invasion of colon cancer cells via miR-107/Par4 axis.

    Long non-coding RNA MIR503HG inhibits the proliferation, migration and invasion of colon cancer cells via miR-107/Par4 axis.
    Han H, Li H, Zhou J.

    03/6/2021
    Long non-coding RNA MIR503HG serves as a tumor suppressor in non-small cell lung cancer mediated by wnt1.

    Long non-coding RNA MIR503HG serves as a tumor suppressor in non-small cell lung cancer mediated by wnt1.
    Lin H, Li P, Zhang N, Cao L, Gao YF, Ping F.

    12/19/2020
    Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p.

    Knockdown of lncRNA MIR503HG suppresses proliferation and promotes apoptosis of non-small cell lung cancer cells by regulating miR-489-3p and miR-625-5p.
    Dao R, Wudu M, Hui L, Jiang J, Xu Y, Ren H, Qiu X.

    11/21/2020
    LncRNA MIR503HG inhibits cell migration and invasion via miR-103/OLFM4 axis in triple negative breast cancer.

    LncRNA MIR503HG inhibits cell migration and invasion via miR-103/OLFM4 axis in triple negative breast cancer.
    Fu J, Dong G, Shi H, Zhang J, Ning Z, Bao X, Liu C, Hu J, Liu M, Xiong B., Free PMC Article

    08/13/2020
    Long non-coding RNA MIR503HG functions as a tumor suppressor and inhibits cell proliferation, metastasis and epithelial-mesenchymal transition in bladder cancer.

    lncRNA MIR503HG functioned as a tumor suppressor and inhibited cell proliferation, metastasis and epithelial-mesenchymal transition in bladder cancer.
    Qiu F, Zhang MR, Zhou Z, Pu JX, Zhao XJ.

    07/25/2020
    MIR503HG inhibited the proliferation, invasion, and migration of HTR-8/SVneo and JEG3 cells via regulating matrix metalloproteinases and NF-kB signaling.

    The Increased lncRNA MIR503HG in Preeclampsia Modulated Trophoblast Cell Proliferation, Invasion, and Migration via Regulating Matrix Metalloproteinases and NF-κB Signaling.
    Cheng D, Jiang S, Chen J, Li J, Ao L, Zhang Y., Free PMC Article

    02/15/2020
    Low MIR503HG expression is associated with colorectal cancer.

    LncRNA MIR503HG is downregulated in Han Chinese with colorectal cancer and inhibits cell migration and invasion mediated by TGF-β2.
    Chuo D, Liu F, Chen Y, Yin M.

    08/10/2019
    The current study showed that MIR503HG enhances the growth ability of ALK-negative ALCL by protecting and activating components of the miR-503/Smuf2/ TGFBR pathway.

    The Long Non-Coding RNA MIR503HG Enhances Proliferation of Human ALK-Negative Anaplastic Large-Cell Lymphoma.
    Huang PS, Chung IH, Lin YH, Lin TK, Chen WJ, Lin KH., Free PMC Article

    09/29/2018
    lincRNAs MIR503HG and LINC00629 impaired migration and invasion capacities in a choriocarcinoma in vitro model, indicating a potential role in human reproduction and tumorigenesis.

    Placenta-Enriched LincRNAs MIR503HG and LINC00629 Decrease Migration and Invasion Potential of JEG-3 Cell Line.
    Muys BR, Lorenzi JC, Zanette DL, Lima e Bueno Rde B, de Araújo LF, Dinarte-Santos AR, Alves CP, Ramão A, de Molfetta GA, Vidal DO, Silva WA Jr., Free PMC Article

    09/10/2016
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