| CILP is a potential pan-cancer marker: combined silico study and in vitro analyses. | CILP is a potential pan-cancer marker: combined silico study and in vitro analyses.
Guo B, Zhao F, Zhang S. | 01/29/2024 |
| CILP-1 Is a Biomarker for Backward Failure and Right Ventricular Dysfunction in HFrEF. | CILP-1 Is a Biomarker for Backward Failure and Right Ventricular Dysfunction in HFrEF.
Weidenhammer A, Prausmüller S, Partsch C, Spinka G, Luckerbauer B, Larch M, Arfsten H, Abdel Mawgoud R, Bartko PE, Goliasch G, Kastl S, Hengstenberg C, Hülsmann M, Pavo N., Free PMC Article | 01/3/2024 |
| CILP gene polymorphism (rs2073711) is associated with a lower risk of lumbar disc degeneration. | Association of CILP, COL9A2 and MMP3 Gene Polymorphisms with Lumbar Disc Degeneration in an Indian Population.
S M H, M K S, G K C, I Bhat D. | 01/26/2019 |
| CILP rs2073711 TT is associated with increased risk of symmetrical hand osteoarthritis particularly in individuals with low variation in work tasks. | Functional polymorphisms in asporin and CILP together with joint loading predispose to hand osteoarthritis.
Taipale M, Solovieva S, Leino-Arjas P, Männikkö M., Free PMC Article | 01/20/2018 |
| Meta-analysis. Our results confirm the positive association between CILP and intervertebral disc degeneration, providing novel clues for clarifying the role of CILP in the development of IVD. | Association Between Cartilage Intermediate Layer Protein and Degeneration of Intervertebral Disc: A Meta-analysis.
Wang W, Hao J, Zheng S, Xiao X, Wen Y, He A, Guo X, Zhang F. | 05/20/2017 |
| CILP is involved in the etiology of intervertebral disc degeneration among young adults. | Genetic susceptibility of intervertebral disc degeneration among young Finnish adults.
Kelempisioti A, Eskola PJ, Okuloff A, Karjalainen U, Takatalo J, Daavittila I, Niinimäki J, Sequeiros RB, Tervonen O, Solovieva S, Kao PY, Song YQ, Cheung KM, Chan D, Ala-Kokko L, Järvelin MR, Karppinen J, Männikkö M., Free PMC Article | 02/4/2012 |
| The researchers found that the single nucleotide polymorphism (1184T/C) of the CILP gene is associated an increased risk of lumbar disc degeneration in male athletes. | Cartilage intermediate layer protein gene is associated with lumbar disc degeneration in male, but not female, collegiate athletes.
Min SK, Nakazato K, Yamamoto Y, Gushiken K, Fujimoto H, Fujishiro H, Kobayakawa Y, Hiranuma K, Min SK, Nakazato K, Yamamoto Y, Gushiken K, Fujimoto H, Fujishiro H, Kobayakawa Y, Hiranuma K. | 04/2/2011 |
| the CILP gene 1184T/C polymorphism is a significant risk factor for lumbar disc degeneration occurrence in Japanese collegiate judo athletes | The cartilage intermediate layer protein gene is associated with lumbar disc degeneration in collegiate judokas.
Min SK, Nakazato K, Okada T, Ochi E, Hiranuma K. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (2) articlesCartilage intermediate layer protein gene is associated with lumbar disc degeneration in male, but not female, collegiate athletes.
Min SK, Nakazato K, Yamamoto Y, Gushiken K, Fujimoto H, Fujishiro H, Kobayakawa Y, Hiranuma K, Min SK, Nakazato K, Yamamoto Y, Gushiken K, Fujimoto H, Fujishiro H, Kobayakawa Y, Hiranuma K. Reproducible genetic associations between candidate genes and clinical knee osteoarthritis in men and women.
Valdes AM, Van Oene M, Hart DJ, Surdulescu GL, Loughlin J, Doherty M, Spector TD. | 03/13/2008 |
| CILP regulates TGF-beta signaling and that this regulation has a crucial role in the etiology and pathogenesis of LDD. | A functional SNP in CILP, encoding cartilage intermediate layer protein, is associated with susceptibility to lumbar disc disease.
Seki S, Kawaguchi Y, Chiba K, Mikami Y, Kizawa H, Oya T, Mio F, Mori M, Miyamoto Y, Masuda I, Tsunoda T, Kamata M, Kubo T, Toyama Y, Kimura T, Nakamura Y, Ikegawa S. | 01/21/2010 |
| These observations, together with the finding that CILP protein binds and inhibits TGF-beta1, suggest that CILP and TGF-beta1 may form a functional feedback loop that controls chondrocyte metabolism. | Transcriptional regulation of the cartilage intermediate layer protein (CILP) gene.
Mori M, Nakajima M, Mikami Y, Seki S, Takigawa M, Kubo T, Ikegawa S. | 01/21/2010 |
| SNP analysis suggested that the CILP gene is not a major risk factor for symptoms of lumbar disc disease in Finnish or Chinese populations. | Phenotypic and population differences in the association between CILP and lumbar disc disease.
Virtanen IM, Song YQ, Cheung KM, Ala-Kokko L, Karppinen J, Ho DW, Luk KD, Yip SP, Leong JC, Cheah KS, Sham P, Chan D., Free PMC Article | 01/21/2010 |