| Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin beta1 in Kawasaki disease. | Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease.
Huang J, Zhao C, Zhang S., Free PMC Article | 05/16/2024 |
| Differential expression of Semaphorin-7A /CD163-positive macrophages in large artery and cardiogenic stroke. | Differential expression of Semaphorin-7A /CD163-positive macrophages in large artery and cardiogenic stroke.
Jiang Y, Sun Z, Ge Z, Tao Z, Liu M, Zhong W, Dong N, Xu L, Wang H, Xu Y, Shen X., Free PMC Article | 03/4/2024 |
| Semaphorin 7a aggravates TGF-beta1-induced airway EMT through the FAK/ERK1/2 signaling pathway in asthma. | Semaphorin 7a aggravates TGF-β1-induced airway EMT through the FAK/ERK1/2 signaling pathway in asthma.
Peng H, Sun F, Jiang Y, Guo Z, Liu X, Zuo A, Lu D., Free PMC Article | 12/4/2023 |
| Serum Sema7A is increased in patients with acute aortic dissection. | Serum Sema7A is increased in patients with acute aortic dissection.
Lyu X, Liu X, Gong H, Liu Y, Zhou Z, Hu M, Zhang X. | 10/30/2023 |
| A Comprehensive Prognostic Analysis of Tumor-Related Blood Group Antigens in Pan-Cancers Suggests That SEMA7A as a Novel Biomarker in Kidney Renal Clear Cell Carcinoma. | A Comprehensive Prognostic Analysis of Tumor-Related Blood Group Antigens in Pan-Cancers Suggests That SEMA7A as a Novel Biomarker in Kidney Renal Clear Cell Carcinoma.
Wang Y, Li C, Qi X, Yao Y, Zhang L, Zhang G, Xie L, Wang Q, Zhu W, Guo X., Free PMC Article | 08/27/2022 |
| Anoikis resistance in mammary epithelial cells is mediated by semaphorin 7a. | Anoikis resistance in mammary epithelial cells is mediated by semaphorin 7a.
Rutherford TR, Elder AM, Lyons TR., Free PMC Article | 02/5/2022 |
| The Expression of Semaphorin 7A in Human Periapical Lesions. | The Expression of Semaphorin 7A in Human Periapical Lesions.
Song Y, Wang L, Li J, Yang F, Gao Y, Song D, Sun J, Ye L, Zhang L, Huang D. | 10/2/2021 |
| Sema7A is crucial for resolution of severe inflammation. | Sema7A is crucial for resolution of severe inflammation.
Körner A, Bernard A, Fitzgerald JC, Alarcon-Barrera JC, Kostidis S, Kaussen T, Giera M, Mirakaj V., Free PMC Article | 08/14/2021 |
| Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats. | Sema7A, a brain immune regulator, regulates seizure activity in PTZ-kindled epileptic rats.
Deng J, Xu T, Yang J, Zhang KM, Li Q, Yu XY, Li R, Fu J, Jiang Q, Ma JX, Chen YM., Free PMC Article | 06/26/2021 |
| Hormonal Regulation of Semaphorin 7a in ER(+) Breast Cancer Drives Therapeutic Resistance. | Hormonal Regulation of Semaphorin 7a in ER(+) Breast Cancer Drives Therapeutic Resistance.
Crump LS, Wyatt GL, Rutherford TR, Richer JK, Porter WW, Lyons TR., Free PMC Article | 05/8/2021 |
| Semaphorin 7A promotes endothelial to mesenchymal transition through ATF3 mediated TGF-beta2/Smad signaling. | Semaphorin 7A promotes endothelial to mesenchymal transition through ATF3 mediated TGF-β2/Smad signaling.
Hong L, Li F, Tang C, Li L, Sun L, Li X, Zhu L., Free PMC Article | 04/24/2021 |
| Antibodies against a short region of PfRipr inhibit Plasmodium falciparum merozoite invasion and PfRipr interaction with Rh5 and SEMA7A. | Antibodies against a short region of PfRipr inhibit Plasmodium falciparum merozoite invasion and PfRipr interaction with Rh5 and SEMA7A.
Nagaoka H, Kanoi BN, Ntege EH, Aoki M, Fukushima A, Tsuboi T, Takashima E., Free PMC Article | 12/5/2020 |
| High Serum semaphorin 7A level is associated with the risk of acute atherothrombotic stroke. | Serum semaphorin 7A is associated with the risk of acute atherothrombotic stroke.
You T, Zhu Z, Zheng X, Zeng N, Hu S, Liu Y, Ren L, Lu Q, Tang C, Ruan C, Zhang Y, Zhu L., Free PMC Article | 07/25/2020 |
| Study reports that soluble SEMA7A is elevated in plasma of patients with acute Myocardial infarction (MI), and that Semaphorin 7A holds significant impact on the extent of MI reperfusion injury. In mouse model Sema7a promotes myocardial thrombo-inflammation and tissue damage by reinforcing platelet thrombotic activity and platelet-neutrophil complexes formation through a platelet GPIb-dependent mechanism. | Red blood cell-derived semaphorin 7A promotes thrombo-inflammation in myocardial ischemia-reperfusion injury through platelet GPIb.
Köhler D, Granja T, Volz J, Koeppen M, Langer HF, Hansmann G, Legchenko E, Geisler T, Bakchoul T, Eggstein C, Häberle HA, Nieswandt B, Rosenberger P., Free PMC Article | 07/18/2020 |
| this study shows that semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells | Semaphorin 7A modulates cytokine-induced memory-like responses by human natural killer cells.
Ghofrani J, Lucar O, Dugan H, Reeves RK, Jost S., Free PMC Article | 05/30/2020 |
| Sema3A and Sema7A gene polymorphisms are not related to systemic lupus erythematosus genetic susceptibility, but may link to several clinical features of systemic lupus erythematosus. | Semaphorin-3A, semaphorin-7A gene single nucleotide polymorphisms, and systemic lupus erythematosus susceptibility.
Liu LN, Wang P, Zou YF, Xu Z, Cheng J, Zhang Y, Hu W, Pan HF. | 05/16/2020 |
| The LOXL1-AS1/miR-28-5p/SEMA7A axis facilitated pancreatic cancer progression, which may be regarded as an innovative therapeutic target for PC treatment. | LncRNA LOXL1-AS1/miR-28-5p/SEMA7A axis facilitates pancreatic cancer progression.
Liu Y, Guo C, Li F, Wu L. | 03/21/2020 |
| Semaphorin-7A promoted growth and migration of oral tongue squamous cell carcinoma by regulating transforming growth factor-beta induced epithelial mesenchymal transition. | Semaphorin-7A contributes to growth, migration and invasion of oral tongue squamous cell carcinoma through TGF-β-mediated EMT signaling pathway.
Liu TJ, Guo JL, Wang HK, Xu X. | 11/9/2019 |
| SEMA7A, which is expressed on mammary cells during glandular involution, alters macrophage biology and lymphangiogenesis to drive breast cancer metastasis | Semaphorin 7A Promotes Macrophage-Mediated Lymphatic Remodeling during Postpartum Mammary Gland Involution and in Breast Cancer.
Elder AM, Tamburini BAJ, Crump LS, Black SA, Wessells VM, Schedin PJ, Borges VF, Lyons TR., Free PMC Article | 10/12/2019 |
| Sema7A has a significant role in atherosclerosis by mediating endothelial dysfunction in a beta1 integrin-dependent manner. | Vascular Semaphorin 7A Upregulation by Disturbed Flow Promotes Atherosclerosis Through Endothelial β1 Integrin.
Hu S, Liu Y, You T, Heath J, Xu L, Zheng X, Wang A, Wang Y, Li F, Yang F, Cao Y, Zhang H, van Gils JM, van Zonneveld AJ, Jo H, Wu Q, Zhang Y, Tang C, Zhu L., Free PMC Article | 01/19/2019 |
| These findings indicate that Sema7A as a potent activator of T cells and monocytes in the immune response contributes to the inflammation and progression of rheumatoid arthritis | Semaphorin 7A as a potential immune regulator and promising therapeutic target in rheumatoid arthritis.
Xie J, Wang H., Free PMC Article | 11/25/2017 |
| short hairpin-mediated silencing of SEMA7A reveals roles for semaphorin 7a in the promotion of DCIS growth, motility and invasion as well as lymphangiogenesis in the tumor microenvironment. Our studies also uncover a relationship between COX-2 and semaphorin 7a expression and suggest that semaphorin 7a promotes tumor cell invasion on collagen and lymphangiogenesis via activation of b1-integrin receptor | Semaphorin 7a exerts pleiotropic effects to promote breast tumor progression.
Black SA, Nelson AC, Gurule NJ, Futscher BW, Lyons TR., Free PMC Article | 09/2/2017 |
| Our results identified FGL2, GAL, SEMA4D, SEMA7A, and IDO1 as new candidate genes that could be involved in MSCs-mediated immunomodulation. FGL2, GAL, SEMA4D, SEMA7A, and IDO1 genes appeared to be differentially transcribed in the different MSC populations. Moreover, these genes were not similarly modulated following MSCs-exposure to inflammatory signals | Identification and Evaluation of New Immunoregulatory Genes in Mesenchymal Stromal Cells of Different Origins: Comparison of Normal and Inflammatory Conditions.
Fayyad-Kazan M, Najar M, Fayyad-Kazan H, Raicevic G, Lagneaux L., Free PMC Article | 06/3/2017 |
| Sema3A and sema7A expression correlated with the inflammatory activity of the multiple sclerosis (MS) lesions, suggesting their involvement in the immunological process that takes place in MS. | Expression of semaphorin 3A, semaphorin 7A and their receptors in multiple sclerosis lesions.
Costa C, Martínez-Sáez E, Gutiérrez-Franco A, Eixarch H, Castro Z, Ortega-Aznar A, Ramón Y Cajal S, Montalban X, Espejo C. | 08/27/2016 |
| SEMA7A has a role in the development of lung injury | Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury.
Roth JM, Köhler D, Schneider M, Granja TF, Rosenberger P., Free PMC Article | 07/30/2016 |