| Resistin-like beta reduction is associated to low survival rate and is downregulated by adjuvant therapy in colorectal cancer patients. | Resistin-like beta reduction is associated to low survival rate and is downregulated by adjuvant therapy in colorectal cancer patients.
Di Rosa M, Di Cataldo A, Broggi G, Caltabiano R, Tibullo D, Castrogiovanni P, Imbesi R, Lanteri R, Salomone F, Raciti G, Li Volti G., Free PMC Article | 02/4/2023 |
| Investigating resistin like beta (RETNLB) as a tumor promoter for oral squamous cell carcinoma. | Investigating resistin like beta (RETNLB) as a tumor promoter for oral squamous cell carcinoma.
Jin H, Miao H, Nie YW, Lin YY., Free PMC Article | 07/17/2021 |
| Helicobacter pylori Infection Facilitates the Expression of Resistin-like Molecule Beta in Gastric Carcinoma and Precursor Lesions. | Helicobacter pylori Infection Facilitates the Expression of Resistin-like Molecule Beta in Gastric Carcinoma and Precursor Lesions.
Li HJ, Fang EH, Wang JQ, Zheng LD, Tong QS. | 10/24/2020 |
| Plasma RELMbeta levels in necrotizing enterocolitis group were significantly higher than control group. | Early diagnosis of necrotizing enterocolitis by plasma RELMβ and thrombocytopenia in preterm infants: A pilot study.
Luo J, Li HP, Xu F, Wu BQ, Lin HC. | 02/1/2020 |
| Investigated the function and mechanism of RELM-beta in TGF-beta1-induced endothelium-mesenchymal transition in endothelial cell lines. We found that TGF-beta1 stimulation significantly upregulated RELM-beta expression; RELM-beta knockdown could attenuate TGF-beta1-induced cell proliferation and migration of endothelial cell lines. | TGF-β1-induced SMAD2/3/4 activation promotes RELM-β transcription to modulate the endothelium-mesenchymal transition in human endothelial cells.
Jiang Y, Zhou X, Hu R, Dai A. | 06/15/2019 |
| RELMbeta-overexpression can facilitate invasion and migration of gastric carcinoma cells. | Resistin-Like Molecule-β Promotes Invasion and Migration of Gastric Carcinoma Cells.
Jiang R, Zhao C, Wang X, Wang S, Sun X, Tian Y, Song W., Free PMC Article | 12/17/2016 |
| RELMbeta levels were increased in Abdominal aortic aneurysm patients in the serum and in the aortic tissue. Increased RELMbeta levels may be involved in the pathogenesis of AAA formation and progress. | Association of resistin-like molecule β levels and abdominal aortic aneurysm.
Meng X, Kong J, Zhang K, Yang J, Li J, Zhang Y. | 05/14/2016 |
| The data demonstrated that RELM-a is a promising novel biomarker of angiogenesis in patients with gastric cancer. | High expression of RELM-α correlates with poor prognosis and promotes angiogenesis in gastric cancer.
Chen P, Zhao D, Wang W, Zhang Y, Yuan Y, Wang L, Wu Y. | 03/19/2016 |
| elevated RELM-beta expression in asthmatic airways contributes to airways remodelling at least partly by increasing fibroblast proliferation and differentiation with resulting deposition of extracellular matrix proteins. | Resistin-like molecule-β (RELM-β) targets airways fibroblasts to effect remodelling in asthma: from mouse to man.
Fang CL, Yin LJ, Sharma S, Kierstein S, Wu HF, Eid G, Haczku A, Corrigan CJ, Ying S., Free PMC Article | 01/16/2016 |
| It is concluded that proper exercise training prevents up-regulation of FIZZ1/RELMalpha induced by cigarette smoking, which may be involved in the mechanism of proper exercise training modulating airway hyperresponsiveness. | Exercise training attenuated chronic cigarette smoking-induced up-regulation of FIZZ1/RELMα in lung of rats.
Ma WL, Cai PC, Xiong XZ, Ye H. | 09/13/2014 |
| RELMbeta is abundantly expressed in foam cells within plaques and contributes to atherosclerosis development via lipid accumulation and inflammatory facilitation. | Resistin-like molecule β is abundantly expressed in foam cells and is involved in atherosclerosis development.
Kushiyama A, Sakoda H, Oue N, Okubo M, Nakatsu Y, Ono H, Fukushima T, Kamata H, Nishimura F, Kikuchi T, Fujishiro M, Nishiyama K, Aburatani H, Kushiyama S, Iizuka M, Taki N, Encinas J, Sentani K, Ogonuki N, Ogura A, Kawazu S, Yasui W, Higashi Y, Kurihara H, Katagiri H, Asano T. | 09/28/2013 |
| Epithelial cell derived Fizz1 transgene is sufficient to increase bone-marrow derived dendritic cells in the lungs. | Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis.
Madala SK, Edukulla R, Davis KR, Schmidt S, Davidson C, Kitzmiller JA, Hardie WD, Korfhagen TR., Free PMC Article | 08/10/2013 |
| RELM-beta may play an important role not only in animal models of airway remodelling, but also in human airway pathology. | Resistin-like molecule-β is induced following bronchoconstriction of asthmatic airways.
Grainge C, Dulay V, Ward J, Sammut D, Davies E, Green B, Lau L, Cottey L, Haitchi HM, Davies DE, Howarth PH. | 03/2/2013 |
| RELM-beta has the potential to contribute to airway remodelling in diseases such as asthma by acting on epithelial cells to increase proliferation, mucin and growth factor production, at least partly via ERK/MAPK-PI3K/Akt signalling pathways. | Resistin-like molecule-β is a human airway remodelling mediator.
Fang C, Meng Q, Wu H, Eid G, Zhang G, Zhang X, Yang S, Huang K, Lee TH, Corrigan CJ, Ying S. | 06/2/2012 |
| Data show that over-expression of RELMbeta abolishes the invasion, metastasis and angiogenesis of gastric cancer cells in vitro. | Effects of resistin-like molecule β over-expression on gastric cancer cells in vitro.
Zheng LD, Yang CL, Qi T, Qi M, Tong L, Tong QS., Free PMC Article | 04/28/2012 |
| High RELMbeta is associated with colorectal cancer. | Plasma levels of resistin-like molecule beta in humans.
Neilson AP, Djuric Z, Land S, Kato I., Free PMC Article | 01/21/2012 |
| FIZZ2 is highly induced in lungs of human patients with idiopathic pulmonary fibrosis. | FIZZ2/RELM-β induction and role in pulmonary fibrosis.
Liu T, Baek HA, Yu H, Lee HJ, Park BH, Ullenbruch M, Liu J, Nakashima T, Choi YY, Wu GD, Chung MJ, Phan SH., Free PMC Article | 09/3/2011 |
| Gastric cncer patients showing positive RELMbeta expression had a significantly longer overall survival than those with negative expression (P = 0.001). | Expression of resistin-like molecule beta in gastric cancer: its relationship with clinicopathological parameters and prognosis.
Zheng L, Weng M, He J, Yang X, Jiang G, Tong Q. | 02/8/2010 |
| Results suggest that RELM-beta may be involved in the development of scleroderma-associated pulmonary hypertension. | Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension.
Angelini DJ, Su Q, Yamaji-Kegan K, Fan C, Teng X, Hassoun PM, Yang SC, Champion HC, Tuder RM, Johns RA., Free PMC Article | 01/21/2010 |
| Of the 80 colon cancer patients studied, 65 (81.25%) tested positive for RELM beta, mainly in the cytoplasm of colon mucosa. | Enhanced expression of resistin-like molecule beta in human colon cancer and its clinical significance.
Zheng LD, Tong QS, Weng MX, He J, Lv Q, Pu JR, Jiang GS, Cai JB, Liu Y, Hou XH. | 01/21/2010 |
| High levels of RELMbeta can be detected in the stool of mice and humans, where it exists as a homodimer under nonreducing conditions. | Bacterial colonization leads to the colonic secretion of RELMbeta/FIZZ2, a novel goblet cell-specific protein.
He W, Wang ML, Jiang HQ, Steppan CM, Shin ME, Thurnheer MC, Cebra JJ, Lazar MA, Wu GD. | 01/21/2010 |
| Supernatant from COS cells transfected with the CCRG (RETNLB) expression vector stimulated proliferation of colon cancer cells, which supports the growth factor nature of the RETNLB gene. | Bioinformatics-based discovery of a novel factor with apparent specificity to colon cancer.
De Young MP, Damania H, Scheurle D, Zylberberg C, Narayanan R. | 10/2/2003 |