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    ARID5B AT-rich interaction domain 5B [ Homo sapiens (human) ]

    Gene ID: 84159, updated on 12-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Constitutional and acquired genetic variants in ARID5B in pediatric B-cell precursor acute lymphoblastic leukemia.

    Constitutional and acquired genetic variants in ARID5B in pediatric B-cell precursor acute lymphoblastic leukemia.
    Ragnarsson C, Yang M, Moura-Castro LH, Aydın E, Gunnarsson R, Olsson-Arvidsson L, Lilljebjörn H, Fioretos T, Duployez N, Zaliova M, Zuna J, Castor A, Johansson B, Paulsson K.

    06/27/2024
    ARID5B-mediated LINC01128 epigenetically activated pyroptosis and apoptosis by promoting the formation of the BTF3/STAT3 complex in beta2GPI/anti-beta2GPI-treated monocytes.

    ARID5B-mediated LINC01128 epigenetically activated pyroptosis and apoptosis by promoting the formation of the BTF3/STAT3 complex in β2GPI/anti-β2GPI-treated monocytes.
    Tan Y, Qiao J, Yang S, Wang Q, Liu H, Liu Q, Feng W, Yang B, Li Z, Cui L., Free PMC Article

    02/15/2024
    ARID5B, IKZF1, GATA3, CEBPE, and CDKN2A germline polymorphisms and predisposition to childhood acute lymphoblastic leukemia.

    ARID5B, IKZF1, GATA3, CEBPE, and CDKN2A germline polymorphisms and predisposition to childhood acute lymphoblastic leukemia.
    Al-Zayan NR, Ashour MJ, Abuwarda HN, Sharif FA.

    02/15/2024
    ARID5B promoted the histone demethylation of SORBS2 and hampered the metastasis of ovarian cancer.

    ARID5B promoted the histone demethylation of SORBS2 and hampered the metastasis of ovarian cancer.
    Deng Y, Dong Y, Wu L, Zhang Q, Yang L.

    12/5/2023
    ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.

    ARID5B regulates fatty acid metabolism and proliferation at the Pre-B cell stage during B cell development.
    Chalise JP, Ehsani A, Lemecha M, Hung YW, Zhang G, Larson GP, Itakura K., Free PMC Article

    07/27/2023
    [Correlation between ARID5B Gene SNP and MTX Resistance in Children with ALL].

    [Correlation between ARID5B Gene SNP and MTX Resistance in Children with ALL].
    Zhang LF, Ma Y, Li L, Liu WE, Zhang XC.

    05/15/2023
    Contributions of ARID5B, IKZF1, PIP4K2A, and GATA3 Gene Polymorphisms to Childhood Acute Lymphoblastic Leukemia in a Chinese Population.

    Contributions of ARID5B, IKZF1, PIP4K2A, and GATA3 Gene Polymorphisms to Childhood Acute Lymphoblastic Leukemia in a Chinese Population.
    Liu X, Xiao M, Xing Z, Jiang H, Zhu C, Zhang X, Li W, Wang Z, Wu F, Chen Y.

    03/27/2023
    Association of two ARID5B gene variant single nucleotide polymorphisms with acute lymphoblastic leukemia in the Egyptian population.

    Association of two ARID5B gene variant single nucleotide polymorphisms with acute lymphoblastic leukemia in the Egyptian population.
    Gamaleldin MA, Imbaby SAE., Free PMC Article

    02/4/2023
    Molecular Mechanisms of ARID5B-Mediated Genetic Susceptibility to Acute Lymphoblastic Leukemia.

    Molecular Mechanisms of ARID5B-Mediated Genetic Susceptibility to Acute Lymphoblastic Leukemia.
    Zhao X, Qian M, Goodings C, Zhang Y, Yang W, Wang P, Xu B, Tian C, Pui CH, Hunger SP, Raetz EA, Devidas M, Relling MV, Loh ML, Savic D, Li C, Yang JJ., Free PMC Article

    10/1/2022
    Impact of Variants in the ATIC and ARID5B Genes on Therapeutic Failure with Imatinib in Patients with Chronic Myeloid Leukemia.

    Impact of Variants in the ATIC and ARID5B Genes on Therapeutic Failure with Imatinib in Patients with Chronic Myeloid Leukemia.
    Cereja Pantoja KBC, Azevedo TCB, Carvalho DC, Monte N, Cohen Paes AN, Barros MCDC, Vinagre LWMS, Freitas ARS, Burbano RMR, Assumpção PP, Santos SEBD, Fernandes MR, Santos NPCD., Free PMC Article

    04/30/2022
    Transporters, TBC1D4, and ARID5B Variants to Explain Glycated Hemoglobin Variability in Patients with Type 2 Diabetes.

    Transporters, TBC1D4, and ARID5B Variants to Explain Glycated Hemoglobin Variability in Patients with Type 2 Diabetes.
    Gonzalez-Covarrubias V, Sánchez-Ibarra H, Lozano-Gonzalez K, Villicaña S, Texis T, Rodríguez-Dorantes M, Cortés-Ramírez S, Lavalle-Gonzalez F, Soberón X, Barrera-Saldaña H.

    01/29/2022
    Genetic association of ARID5B with the risk of colorectal cancer within Jammu and Kashmir, India.

    Genetic association of ARID5B with the risk of colorectal cancer within Jammu and Kashmir, India.
    Sharma B, Angurana S, Shah R, Verma S, Bhat A, Bhat GR, Bakshi D, Jamwal RS, Tanwar M, Singh S, Bhat A, Vaishnavi S, Kumar R.

    01/22/2022
    ARID5B rs10821936 and rs10994982 gene polymorphism and susceptibility to juvenile systemic lupus erythematosus and lupus nephritis.

    ARID5B rs10821936 and rs10994982 gene polymorphism and susceptibility to juvenile systemic lupus erythematosus and lupus nephritis.
    Mosaad YM, Hammad A, AlHarrass MF, Sallam R, Shouma A, Hammad E, Ahmed EO, Abdel-Azeem HA, Sherif D, Fawzy I, Elbahnasawy A, Abdel Twab H.

    12/18/2021
    Novel phenotypes observed in patients with ETV6-linked leukaemia/familial thrombocytopenia syndrome and a biallelic ARID5B risk allele as leukaemogenic cofactor.

    Novel phenotypes observed in patients with ETV6-linked leukaemia/familial thrombocytopenia syndrome and a biallelic ARID5B risk allele as leukaemogenic cofactor.
    Karastaneva A, Nebral K, Schlagenhauf A, Baschin M, Palankar R, Juch H, Heitzer E, Speicher MR, Höfler G, Grigorow I, Urban C, Benesch M, Greinacher A, Haas OA, Seidel MG.

    06/12/2021
    ARID5B Influences Antimetabolite Drug Sensitivity and Prognosis of Acute Lymphoblastic Leukemia.

    ARID5B Influences Antimetabolite Drug Sensitivity and Prognosis of Acute Lymphoblastic Leukemia.
    Xu H, Zhao X, Bhojwani D, E S, Goodings C, Zhang H, Seibel NL, Yang W, Li C, Carroll WL, Evans WE, Yang JJ., Free PMC Article

    10/3/2020
    ARID5B rs7089424 and rs10994982 might serve as genetic susceptibility markers for B-ALL in Chinese pediatric population.

    Genetic polymorphisms of ARID5B rs7089424 and rs10994982 are associated with B-lineage ALL susceptibility in Chinese pediatric population.
    Tao R, Liu YJ, Liu LF, Li W, Zhao Y, Li HM, Yi XL, Zhao ZY.

    06/27/2020
    The SNPs of ARID5B rs10821936 and rs10994982 were not found to be strongly associated with ALL outcomes.

    ARID5B rs10821936 and rs10994982 gene polymorphisms and acute lymphoblastic leukemia: relation to disease susceptibility and outcome.
    Mosaad YM, Khashaba M, Darwish A, Darwish M, Elwassefy M, Abdelmabood S, Fawzy IM, Youssef LF, Elbasiouny RA.

    04/11/2020
    findings indicate that the ARID5B variants (rs10821936, rs10994982, rs7089424) are significantly associated with the risk of childhood acute lymphoblastic leukemia.

    ARID5B gene polymorphisms and the risk of childhood acute lymphoblastic leukemia: a meta-analysis.
    Yang JL, Liu YN, Bi YY, Wang H.

    12/14/2019
    ARID5B polymorphisms contribute to male Acute promyelocytic leukemia risk, clinical feature, and prognosis, suggesting the importance of ARDI5B in Acute myeloid leukemia pathogenesis and development, and the gender and subtype preference may prompt some specific mechanisms of ARID5B. Besides, ARID5B polymorphisms might be a potential prognosis biomarker.

    ARID5B Genetic Polymorphisms Contribute to the Susceptibility and Prognosis of Male Acute Promyelocytic Leukemia.
    Zhou J, Gou H, Zhang L, Wang X, Ye Y, Lu X, Ying B.

    12/7/2019
    Variants in ARID5B gene are associated with the development of acute lymphoblastic leukemia in Mexican children.

    Variants in ARID5B gene are associated with the development of acute lymphoblastic leukemia in Mexican children.
    Reyes-León A, Ramírez-Martínez M, Fernández-García D, Amaro-Muñoz D, Velázquez-Aragón JA, Salas-Labadía C, Zapata-Tarrés M, Velasco-Hidalgo L, López-Santiago N, López-Ruiz MI, Malavar-Guadarrama MA, Cárdenas-Cardós R, Paredes-Aguilera R, Rivera-Luna R, Dean M, Pérez-Vera P.

    09/21/2019
    data demonstrate that ARID5B is a key regulator of metabolism in human adaptive NK cells, which, if targeted, may be of therapeutic value.

    ARID5B regulates metabolic programming in human adaptive NK cells.
    Cichocki F, Wu CY, Zhang B, Felices M, Tesi B, Tuininga K, Dougherty P, Taras E, Hinderlie P, Blazar BR, Bryceson YT, Miller JS., Free PMC Article

    09/7/2019
    Our study revealed that AR transcription is positively regulated by ARID5B through H3K4me3 recruitment in the AR promoter.

    AT-rich interactive domain 5B regulates androgen receptor transcription in human prostate cancer cells.
    Yamakawa T, Waer C, Itakura K.

    06/1/2019
    It was found that the variants rs10740055 of ARID5B and rs6964823 of IKZF1 act individually and additively as risk factors in the development of leukemia in the populations of Northern India. The variants rs6964823 (IKZF1) and rs10740055 (ARID5B) showed significant associations with odds ratio (OR) and p-values of 1.5 (1.0-2.3 at 95% confidence interval [CI]) and 0.04; and 2.5 (1.5-4.1 at 95% CI) and 0.0002, respectively

    Association of ARID5B and IKZF1 Variants with Leukemia from Northern India.
    Bhat A, Shah R, Bhat GR, Verma S, Sharma V, Sharma I, Pandita M, Bakshi D, Sharma B, Suri J, Kumar R.

    05/25/2019
    Differential methylation and expression of ARID5B to be associated with human atherosclerosis.

    Blood monocyte transcriptome and epigenome analyses reveal loci associated with human atherosclerosis.
    Liu Y, Reynolds LM, Ding J, Hou L, Lohman K, Young T, Cui W, Huang Z, Grenier C, Wan M, Stunnenberg HG, Siscovick D, Hou L, Psaty BM, Rich SS, Rotter JI, Kaufman JD, Burke GL, Murphy S, Jacobs DR Jr, Post W, Hoeschele I, Bell DA, Herrington D, Parks JS, Tracy RP, McCall CE, Stein JH., Free PMC Article

    07/28/2018
    The present results identified MRF2/ARID5B as a potential susceptibility gene for new-onset T2DM in a Northern Chinese population, while the rs7087507 SNP was associated with HDL-C levels. Further larger studies are required to validate these findings.

    Relationship between Modulator Recognition Factor 2/AT-rich Interaction Domain 5B Gene Variations and Type 2 Diabetes Mellitus or Lipid Metabolism in a Northern Chinese Population.
    Sun LL, Zhang SJ, Chen MJ, Elena K, Qiao H., Free PMC Article

    03/3/2018
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