| Expression analysis of plvap in mouse heart development, homeostasis and injury. | Expression analysis of plvap in mouse heart development, homeostasis and injury.
Sui Y, Kou S, Ge K, Cao J, Liu C, Zhang H. | 12/6/2023 |
| A Potential New Role for Zinc in Age-Related Macular Degeneration through Regulation of Endothelial Fenestration. | A Potential New Role for Zinc in Age-Related Macular Degeneration through Regulation of Endothelial Fenestration.
Cunningham F, Cahyadi S, Lengyel I., Free PMC Article | 01/8/2022 |
| PV1 in Caveolae Controls Lung Endothelial Permeability. | PV1 in Caveolae Controls Lung Endothelial Permeability.
Jones JH, Friedrich E, Hong Z, Minshall RD, Malik AB., Free PMC Article | 11/28/2020 |
| Fenestral diaphragms and PLVAP associations in liver sinusoidal endothelial cells are developmentally regulated. | Fenestral diaphragms and PLVAP associations in liver sinusoidal endothelial cells are developmentally regulated.
Auvinen K, Lokka E, Mokkala E, Jäppinen N, Tyystjärvi S, Saine H, Peurla M, Shetty S, Elima K, Rantakari P, Salmi M., Free PMC Article | 10/31/2020 |
| Retinal VEGFA maintains the ultrastructure and function of choriocapillaris by preserving the endothelial PLVAP. | Retinal VEGFA maintains the ultrastructure and function of choriocapillaris by preserving the endothelial PLVAP.
Kim SA, Kim SJ, Choi YA, Yoon HJ, Kim A, Lee J. | 08/22/2020 |
| These results show that Plvap expression in endothelial cells is important in the maintenance of IgM(+) B cells in the spleen and peritoneal cavity. | Endothelial Plasmalemma Vesicle-Associated Protein Regulates the Homeostasis of Splenic Immature B Cells and B-1 B Cells.
Elgueta R, Tse D, Deharvengt SJ, Luciano MR, Carriere C, Noelle RJ, Stan RV., Free PMC Article | 08/12/2017 |
| an endothelium-specific molecule, plasmalemma vesicle-associated protein (PLVAP), regulates the seeding of fetal monocyte-derived macrophages to tissues in mice | Fetal liver endothelium regulates the seeding of tissue-resident macrophages.
Rantakari P, Jäppinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M. | 03/11/2017 |
| Results indicate that PLVAP is not only required for the formation of endothelial diaphragms, but also for the formation of endothelial fenestrae, even of those without diaphragms. | Formation of fenestrae in murine liver sinusoids depends on plasmalemma vesicle-associated protein and is required for lipoprotein passage.
Herrnberger L, Hennig R, Kremer W, Hellerbrand C, Goepferich A, Kalbitzer HR, Tamm ER., Free PMC Article | 08/29/2015 |
| In the lymphatic sinus, PLVAP forms a physical sieve that regulates the parenchymal entry of lymphocytes and soluble antigens. | The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes.
Rantakari P, Auvinen K, Jäppinen N, Kapraali M, Valtonen J, Karikoski M, Gerke H, Iftakhar-E-Khuda I, Keuschnigg J, Umemoto E, Tohya K, Miyasaka M, Elima K, Jalkanen S, Salmi M. | 05/23/2015 |
| PV1 is involved in the tumor angiogenesis | PV1 down-regulation via shRNA inhibits the growth of pancreatic adenocarcinoma xenografts.
Deharvengt SJ, Tse D, Sideleva O, McGarry C, Gunn JR, Longnecker DS, Carriere C, Stan RV., Free PMC Article | 01/11/2014 |
| formation of diaphragms is the only role of PV1 | Caveolae, fenestrae and transendothelial channels retain PV1 on the surface of endothelial cells.
Tkachenko E, Tse D, Sideleva O, Deharvengt SJ, Luciano MR, Xu Y, McGarry CL, Chidlow J, Pilch PF, Sessa WC, Toomre DK, Stan RV., Free PMC Article | 07/14/2012 |
| upregulation of microvascular expression of PV-1 post-spinal cord injury may promote major components of secondary injury | Spinal microvascular expression of PV-1 is associated with inflammation, perivascular astrocyte loss, and diminished EC glucose transport potential in acute SCI.
Mozer AB, Whittemore SR, Benton RL. | 11/13/2010 |
| PV-1 is necessary for fenestral pore architecture and the ordered arrangement of fenestrae in sieve plates. | An in vitro assay reveals a role for the diaphragm protein PV-1 in endothelial fenestra morphogenesis.
Ioannidou S, Deinhardt K, Miotla J, Bradley J, Cheung E, Samuelsson S, Ng YS, Shima DT., Free PMC Article | 01/21/2010 |
| Compelling evidence for a functional role of PV-1 in the formation of large transendothelial channels and modulation of nuclear shape. | PV-1 labels trans-cellular openings in mouse endothelial cells and is negatively regulated by VEGF.
Hnasko R, Carter JM, Medina F, Frank PG, Lisanti MP. | 01/21/2010 |
| The PV-1 protein is negatively regulated in pulmonary endothelial cells by VEGF-R2 signaling. | PV-1 is negatively regulated by VEGF in the lung of caveolin-1, but not caveolin-2, null mice.
Hnasko R, Frank PG, Ben-Jonathan N, Lisanti MP. | 01/21/2010 |