| Expression of HORMAD1 in Chronic Rhinosinusitis and Its Correlation with Inflammatory Factors. | Expression of HORMAD1 in Chronic Rhinosinusitis and Its Correlation with Inflammatory Factors.
Zhang X, Xu Y, Zhou J. | 01/12/2024 |
| Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins. | Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins.
Wang H, Xie R, Niu F, Yang Q, An L, Wu C, Liu X, Yang X. | 12/21/2023 |
| The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks. | The cancer testes antigen, HORMAD1, limits genomic instability in cancer cells by protecting stalled replication forks.
Herrera LR, Johnson RA, McGlynn K, Gibbs ZA, Davis AJ, Whitehurst AW., Free PMC Article | 12/4/2023 |
| Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas. | Ectopically Expressed Meiosis-Specific Cancer Testis Antigen HORMAD1 Promotes Genomic Instability in Squamous Cell Carcinomas.
Gantchev J, Messina-Pacheco J, MartÃnez Villarreal A, Ramchatesingh B, Lefrançois P, Xie P, Amar L, Xu HH, Raveendra K, Sikorski D, Guerra Ordaz DJ, Gill RPK, Lambert M, Litvinov IV., Free PMC Article | 07/5/2023 |
| A biallelic loss of function variant in HORMAD1 within a large consanguineous Turkish family is associated with spermatogenic arrest. | A biallelic loss of function variant in HORMAD1 within a large consanguineous Turkish family is associated with spermatogenic arrest.
Okutman O, Boivin M, Muller J, Charlet-Berguerand N, Viville S. | 02/11/2023 |
| HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance. | HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance.
Zong B, Sun L, Peng Y, Wang Y, Yu Y, Lei J, Zhang Y, Guo S, Li K, Liu S., Free PMC Article | 12/4/2021 |
| HORMAD1-dependent DSB repair as a new mechanism of radioresistance and a probable determinant of mutability in lung adenocarcinoma. | The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells.
Gao Y, Kardos J, Yang Y, Tamir TY, Mutter-Rottmayer E, Weissman B, Major MB, Kim WY, Vaziri C., Free PMC Article | 11/23/2019 |
| HORMAD1 expression specifies a novel subtype of lung adenocarcinoma, which has adapted to mitigate DNA damage | HORMAD1 Is a Negative Prognostic Indicator in Lung Adenocarcinoma and Specifies Resistance to Oxidative and Genotoxic Stress.
Nichols BA, Oswald NW, McMillan EA, McGlynn K, Yan J, Kim MS, Saha J, Mallipeddi PL, LaDuke SA, Villalobos PA, Rodriguez-Canales J, Wistuba II, Posner BA, Davis AJ, Minna JD, MacMillan JB, Whitehurst AW., Free PMC Article | 10/12/2019 |
| Four sterility-related genes, including BOLL, DDX4, HORMAD1, and MAEL, were found to have increased methylation at CpGs of the promoter regions and decreased mRNA expressions in nonobstructive azoospermia and hypospermatogenesis (HS) testis and are believed to be associated with HS. | Causes and Clinical Features of Infertile Men With Nonobstructive Azoospermia and Histopathologic Diagnosis of Hypospermatogenesis.
Cheng YS, Lu CW, Lin TY, Lin PY, Lin YM. | 12/22/2018 |
| Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers | Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers.
Watkins J, Weekes D, Shah V, Gazinska P, Joshi S, Sidhu B, Gillett C, Pinder S, Vanoli F, Jasin M, Mayrhofer M, Isaksson A, Cheang MC, Mirza H, Frankum J, Lord CJ, Ashworth A, Vinayak S, Ford JM, Telli ML, Grigoriadis A, Tutt AN., Free PMC Article | 06/4/2016 |
| Hormad1 and Hormad2 might not be the susceptible genes for the non-obstructive azoospermia in our study population. However, rs718772 of Hormad2 variant might be associated with testis development in NOA patients. | Genetic study of Hormad1 and Hormad2 with non-obstructive azoospermia patients in the male Chinese population.
Song B, He X, Du W, Zhang Y, Ruan J, Zhou F, Zuo XB, Wu H, Zha X, Liu S, Xie XS, Ye L, Wei Z, Zhou P, Cao YX., Free PMC Article | 04/4/2015 |
| HORMAD1 gene silencing resulted in significantly reduced VEGF protein levels and microvessel density compared to controls in epithelial ovarian carcinoma. | Biological significance of HORMA domain containing protein 1 (HORMAD1) in epithelial ovarian carcinoma.
Shahzad MM, Shin YH, Matsuo K, Lu C, Nishimura M, Shen DY, Kang Y, Hu W, Mora EM, Rodriguez-Aguayo C, Kapur A, Bottsford-Miller J, Lopez-Berestein G, Rajkovic A, Sood AK., Free PMC Article | 04/6/2013 |
| This is the first report showing that HORMAD1 single-nucleotide polymorphisms (SNPs) may predispose men to a defect in spermatogenesis, although the causal and potential mechanistic relationships between these HORMAD1 SNPs and azoospermia remain unclear. | Single-nucleotide polymorphisms in HORMAD1 may be a risk factor for azoospermia caused by meiotic arrest in Japanese patients.
Miyamoto T, Tsujimura A, Miyagawa Y, Koh E, Namiki M, Horikawa M, Saijo Y, Sengoku K., Free PMC Article | 12/22/2012 |