| Maintenance of magnesium homeostasis by NUF2 promotes protein synthesis and anaplastic thyroid cancer progression. | Maintenance of magnesium homeostasis by NUF2 promotes protein synthesis and anaplastic thyroid cancer progression.
Bao L, Gong Y, Che Y, Li Y, Xu T, Chen J, Wang S, Tan Z, Huang P, Pan Z, Ge M., Free PMC Article | 09/16/2024 |
| FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner. | FOXM1 promotes neurofibromatosis type 1-associated malignant peripheral nerve sheath tumor progression in a NUF2-dependent manner.
Aimaier R, Chung MH, Gu Y, Yu Q, Wei C, Li H, Guo Z, Long M, Li Y, Wang W, Li Q, Wang Z. | 10/26/2023 |
| NUF2 is correlated with a poor prognosis and immune infiltration in clear cell renal cell carcinoma. | NUF2 is correlated with a poor prognosis and immune infiltration in clear cell renal cell carcinoma.
Zheng B, Wang S, Yuan X, Zhang J, Shen Z, Ge C., Free PMC Article | 08/30/2023 |
| NUF2 Drives Cholangiocarcinoma Progression and Migration via Inhibiting Autophagic Degradation of TFR1. | NUF2 Drives Cholangiocarcinoma Progression and Migration via Inhibiting Autophagic Degradation of TFR1.
Shan J, Jiang W, Chang J, Zhou T, Chen Y, Zhang Y, Wang J, Wang Y, Wang Y, Xu X, Liu S, Shi X, Fan S, Chen R, Li C, Li X., Free PMC Article | 04/19/2023 |
| NUF2 Promotes Breast Cancer Development as a New Tumor Stem Cell Indicator. | NUF2 Promotes Breast Cancer Development as a New Tumor Stem Cell Indicator.
Deng Y, Li J, Zhang Y, Hu H, Wan F, Min H, Zhou H, Gu L, Liao X, Zhou J, Zhou J., Free PMC Article | 02/28/2023 |
| NUF2 promotes tumorigenesis by interacting with HNRNPA2B1 via PI3K/AKT/mTOR pathway in ovarian cancer. | NUF2 promotes tumorigenesis by interacting with HNRNPA2B1 via PI3K/AKT/mTOR pathway in ovarian cancer.
Ren M, Zhao H, Gao Y, Chen Q, Zhao X, Yue W., Free PMC Article | 02/11/2023 |
| NUF2 Drives Clear Cell Renal Cell Carcinoma by Activating HMGA2 Transcription through KDM2A-mediated H3K36me2 Demethylation. | NUF2 Drives Clear Cell Renal Cell Carcinoma by Activating HMGA2 Transcription through KDM2A-mediated H3K36me2 Demethylation.
Lin J, Chen X, Yu H, Min S, Chen Y, Li Z, Xie X., Free PMC Article | 07/23/2022 |
| ANP32E contributes to gastric cancer progression via NUF2 upregulation. | ANP32E contributes to gastric cancer progression via NUF2 upregulation.
Zhu X, Zou Y, Wu T, Ni J, Tan Q, Wang Q, Zhang M., Free PMC Article | 07/23/2022 |
| NUF2 Is a Potential Immunological and Prognostic Marker for Non-Small-Cell Lung Cancer. | NUF2 Is a Potential Immunological and Prognostic Marker for Non-Small-Cell Lung Cancer.
Li X, Zhang L, Yi Z, Zhou J, Song W, Zhao P, Wu J, Song J, Ni Q., Free PMC Article | 05/28/2022 |
| Poly-SUMO-2/3 chain modification of Nuf2 facilitates CENP-E kinetochore localization and chromosome congression during mitosis. | Poly-SUMO-2/3 chain modification of Nuf2 facilitates CENP-E kinetochore localization and chromosome congression during mitosis.
Subramonian D, Chen TA, Paolini N, Zhang XD., Free PMC Article | 02/19/2022 |
| Correlation of NUF2 Overexpression with Poorer Patient Survival in Multiple Cancers. | Correlation of NUF2 Overexpression with Poorer Patient Survival in Multiple Cancers.
Jiang X, Jiang Y, Luo S, Sekar K, Koh CKT, Deivasigamani A, Dong Q, Zhang N, Li S, Hao F, Goh BKP, Ooi LL, Wang Y, Hui KM., Free PMC Article | 02/12/2022 |
| NUF2 as an anticancer therapeutic target and prognostic factor in breast cancer. | NUF2 as an anticancer therapeutic target and prognostic factor in breast cancer.
Lv S, Xu W, Zhang Y, Zhang J, Dong X. | 08/7/2021 |
| A Gene Set Enrichment Analysis indicated that NUF2 may regulate breast carcinogenesis and progression via cell cyclerelated pathways. | Screening of differentially expressed genes and identification of NUF2 as a prognostic marker in breast cancer.
Xu W, Wang Y, Wang Y, Lv S, Xu X, Dong X., Free PMC Article | 12/28/2019 |
| NUF2 was identified to be the minimal biomarker sufficient to discriminate ER tumors from LR tumors. NUF2 in combination with liver cirrhosis could significantly improve the detection of ER tumors with an AUROC of 0.82 and 0.85 in the test and validation cohort, respectively. | NUF2 is a valuable prognostic biomarker to predict early recurrence of hepatocellular carcinoma after surgical resection.
Wang Y, Tan PY, Handoko YA, Sekar K, Shi M, Xie C, Jiang XD, Dong QZ, Goh BKP, Ooi LL, Gao Z, Hui KM. | 12/14/2019 |
| NUF2 gene is overexpressed in breast cancer, and its expression level is important in predicting the prognosis of breast cancer. | [Expression of NUF2 in breast cancer and its clinical significance].
Sun J, Chen J, Wang Z, Deng Y, Liu L, Liu X., Free PMC Article | 08/24/2019 |
| CDCA1 could be a prognostic marker in malignant melanoma patients. | Cell division cycle-associated protein 1 as a new melanoma-associated antigen.
Tokuzumi A, Fukushima S, Miyashita A, Nakahara S, Kubo Y, Yamashita J, Harada M, Nakamura K, Kajihara I, Jinnin M, Ihn H. | 02/3/2018 |
| Results provide evidence that CDCA1 plays a significant role in oral cavity carcinoma (OCC) tumorigenesis. Importantly, CDCA1 is associated with growth and survival of OCC cells where its elevated expression issignificantly associated with poor prognosis . | Cell division cycle associated 1 as a novel prognostic biomarker and therapeutic target for oral cancer.
Thang PM, Takano A, Yoshitake Y, Shinohara M, Murakami Y, Daigo Y. | 04/8/2017 |
| NUF2 modulates cell proliferation via cell cycle control in osteosarcoma Saos-2 cells. | Silencing of NUF2 inhibits proliferation of human osteosarcoma Saos-2 cells.
Fu HL, Shao L. | 12/17/2016 |
| found LncRNA AF339813 was positively regulated by NUF2 | Downregulation of NUF2 inhibits tumor growth and induces apoptosis by regulating lncRNA AF339813.
Hu P, Shangguan J, Zhang L., Free PMC Article | 03/26/2016 |
| NUF2 plays a critical role in the regulation of HCC cell proliferation and apoptosis. | Silencing of NUF2 inhibits tumor growth and induces apoptosis in human hepatocellular carcinomas.
Liu Q, Dai SJ, Li H, Dong L, Peng YP. | 07/25/2015 |
| NUF2 was overexpressed in glioma tissues and differentially expressed in a series of glioma cell lines. Depletion of NUF2 by short-hairpin RNA inhibited cell growth in vitro and in vivo. | SiRNA-mediated knockdown against NUF2 suppresses tumor growth and induces cell apoptosis in human glioma cells.
Huang SK, Qian JX, Yuan BQ, Lin YY, Ye ZX, Huang SS. | 07/25/2015 |
| hnRNP K binds to the promoter region of NUF2 and activates its transcription. | Heterogeneous nuclear ribonucleoprotein K upregulates the kinetochore complex component NUF2 and promotes the tumorigenicity of colon cancer cells.
Sugimasa H, Taniue K, Kurimoto A, Takeda Y, Kawasaki Y, Akiyama T. | 06/27/2015 |
| These results suggest that CDCA1 could be a prognostic biomarker and a potential therapeutic target for colorectal cancers . | Cell division cycle-associated protein 1 overexpression is essential for the malignant potential of colorectal cancers.
Kobayashi Y, Takano A, Miyagi Y, Tsuchiya E, Sonoda H, Shimizu T, Okabe H, Tani T, Fujiyama Y, Daigo Y. | 08/23/2014 |
| these findings demonstrated that three buried glutamic acid-lysine pairs, in concert with hydrophobic interactions of core residues, provide the major specificity and stability requirements for Hec1-Nuf2 dimerization | Complementary interhelical interactions between three buried Glu-Lys pairs within three heptad repeats are essential for Hec1-Nuf2 heterodimerization and mitotic progression.
Ngo B, Hu CM, Guo XE, Ngo B, Wei R, Zhu J, Lee WH., Free PMC Article | 02/22/2014 |
| NDC80, NUF2 and PTN were significantly aberrantly overexpressed in serous adenocarcinomas. | An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer.
Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK., Free PMC Article | 06/1/2013 |