| HAS2 facilitates glioma cell malignancy and suppresses ferroptosis in an FZD7-dependent manner. | HAS2 facilitates glioma cell malignancy and suppresses ferroptosis in an FZD7-dependent manner.
Liu Z, Yu K, Chen K, Liu J, Dai K, Zhao P., Free PMC Article | 09/18/2024 |
| Structural basis of frizzled 7 activation and allosteric regulation. | Structural basis of frizzled 7 activation and allosteric regulation.
Bous J, Kinsolving J, Grätz L, Scharf MM, Voss JH, Selcuk B, Adebali O, Schulte G., Free PMC Article | 09/10/2024 |
| Mechanism of miR-548b-5p down-regulating FZD7 to impede the migratory and invasive behavior of gastric carcinoma cells. | Mechanism of miR-548b-5p down-regulating FZD7 to impede the migratory and invasive behavior of gastric carcinoma cells.
Zhang J, Qin X, Bi Z, Niu R, Zhang K, Mei X, Guo W. | 02/1/2024 |
| WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling. | WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling.
Huang Q, Xiao Y, Lan T, Lu Y, Huang L, Zheng D., Free PMC Article | 01/29/2024 |
| FZD7: A potential biomarker for endometriosis. | FZD7: A potential biomarker for endometriosis.
Lan S, Zhang Z, Li Q., Free PMC Article | 10/12/2023 |
| MiR-1-3p enhances the sensitivity of ovarian cancer cells to ferroptosis by targeting FZD7. | MiR-1-3p enhances the sensitivity of ovarian cancer cells to ferroptosis by targeting FZD7.
Zhang D, Qu B, Hu B, Cao K, Shen H., Free PMC Article | 12/24/2022 |
| An investigation of bacteriocin nisin anti-cancer effects and FZD7 protein interactions in liver cancer cells. | An investigation of bacteriocin nisin anti-cancer effects and FZD7 protein interactions in liver cancer cells.
Balcik-Ercin P, Sever B. | 10/8/2022 |
| FZD7 accelerates hepatic metastases in pancreatic cancer by strengthening EMT and stemness associated with TGF-beta/SMAD3 signaling. | FZD7 accelerates hepatic metastases in pancreatic cancer by strengthening EMT and stemness associated with TGF-β/SMAD3 signaling.
Zhang Z, Xu Y., Free PMC Article | 07/30/2022 |
| Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters. | Epigenetic repression of Wnt receptors in AD: a role for Sirtuin2-induced H4K16ac deacetylation of Frizzled1 and Frizzled7 promoters.
Palomer E, Martín-Flores N, Jolly S, Pascual-Vargas P, Benvegnù S, Podpolny M, Teo S, Vaher K, Saito T, Saido TC, Whiting P, Salinas PC., Free PMC Article | 06/25/2022 |
| GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling. | GIPC2 interacts with Fzd7 to promote prostate cancer metastasis by activating WNT signaling.
Wang L, Wang J, Yin X, Guan X, Li Y, Xin C, Liu J., Free PMC Article | 05/7/2022 |
| A novel humanized Frizzled-7-targeting antibody enhances antitumor effects of Bevacizumab against triple-negative breast cancer via blocking Wnt/beta-catenin signaling pathway. | A novel humanized Frizzled-7-targeting antibody enhances antitumor effects of Bevacizumab against triple-negative breast cancer via blocking Wnt/β-catenin signaling pathway.
Xie W, Zhao H, Wang F, Wang Y, He Y, Wang T, Zhang K, Yang H, Zhou Z, Shi H, Wang J, Huang G., Free PMC Article | 09/4/2021 |
| Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer. | Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer.
Zhang Z, Xu Y, Zhao C., Free PMC Article | 07/24/2021 |
| Frizzled-7 Identifies Platinum-Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis. | Frizzled-7 Identifies Platinum-Tolerant Ovarian Cancer Cells Susceptible to Ferroptosis.
Wang Y, Zhao G, Condello S, Huang H, Cardenas H, Tanner EJ, Wei J, Ji Y, Li J, Tan Y, Davuluri RV, Peter ME, Cheng JX, Matei D., Free PMC Article | 05/8/2021 |
| Concurrent Wnt pathway component expression in breast and colorectal cancer. | Concurrent Wnt pathway component expression in breast and colorectal cancer.
Michelli M, Zougros A, Chatziandreou I, Michalopoulos NV, Lazaris AC, Saetta AA. | 04/3/2021 |
| Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells. | Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells.
Gumber D, Do M, Suresh Kumar N, Sonavane PR, Wu CCN, Cruz LS, Grainger S, Carson D, Gaasterland T, Willert K., Free PMC Article | 03/20/2021 |
| Mechanistically, LncRNA AWPPH was demonstrated to sponge miR-93-3p and promote FZD7 expression, causing activation of Wnt/beta-catenin. | LncRNA AWPPH promotes osteosarcoma progression via activation of Wnt/β-catenin pathway through modulating miR-93-3p/FZD7 axis.
Li C, Wang F, Wei B, Wang L, Kong D. | 06/20/2020 |
| High FZD7 expression is associated with lymph node metastasis in Gastric cancer. | Expression of LGR5, FZD7, TROY, and MIST1 in Perioperatively Treated Gastric Carcinomas and Correlation with Therapy Response.
Freiin Grote A, Halske C, Behrens HM, Krüger S, Wilhelm F, Egberts JH, Röcken C., Free PMC Article | 05/2/2020 |
| High FZD7 expression is associated with glioblastoma. | miR-504 suppresses mesenchymal phenotype of glioblastoma by directly targeting the FZD7-mediated Wnt-β-catenin pathway.
Liu Q, Guan Y, Li Z, Wang Y, Liu Y, Cui R, Wang Y., Free PMC Article | 02/15/2020 |
| Overexpression of FZD7 was associated with poor survival in patients with colon cancer | Overexpression of FZD7 is associated with poor survival in patients with colon cancer.
Ye C, Xu M, Lin M, Zhang Y, Zheng X, Sun Y, Deng Y, Pan J, Xu Z, Lu X, Chi P. | 01/18/2020 |
| Genetic deletion of Fzd7 or treatment with vantictumab was sufficient to inhibit the growth of gastric adenomas with or without mutations to Apc. | Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations.
Flanagan DJ, Barker N, Costanzo NSD, Mason EA, Gurney A, Meniel VS, Koushyar S, Austin CR, Ernst M, Pearson HB, Boussioutas A, Clevers H, Phesse TJ, Vincan E. | 12/14/2019 |
| Results indicate that miR-142-3p may serve as a tumor suppressor in breast cancer by suppressing the expression of oncogene AT-Hook 1a Protein, High Mobility Group (HMGA1) and frizzled 7 protein (FZD7). | Aberrant Expression of miR-142-3p and its Target Gene HMGA1 and FZD7 in Breast Cancer and its Clinical Significance.
Jia XP, Meng LL, Fang JC, Wang HW, Chen J, Zhou J, Wang CN, Jiang WF. | 09/21/2019 |
| The anti-angiogenic assay indicated that rhFzd7 repressed TNBC angiogenesis in vitro and in vivo. Furthermore, the study in vivo showed that rhFzd7 could sensitize TNBC cells to the anti-tumor effect of Docetaxel. | A novel recombinant human Frizzled-7 protein exhibits anti-tumor activity against triple negative breast cancer via abating Wnt/β-catenin pathway.
Xie W, Zhang Y, He Y, Zhang K, Wan G, Huang Y, Zhou Z, Huang G, Wang J. | 05/4/2019 |
| results suggest that Wnt canonical pathway may contribute to tumorigenesis and metastasis, indicating that FZD7 could be a potential therapeutic target for gastric cancer | Frizzled7 Promotes Epithelial-to-mesenchymal Transition and Stemness Via Activating Canonical Wnt/β-catenin Pathway in Gastric Cancer.
Li G, Su Q, Liu H, Wang D, Zhang W, Lu Z, Chen Y, Huang X, Li W, Zhang C, He Y, Fu L, Bi J., Free PMC Article | 04/6/2019 |
| miR-504-meidated FZD7/Wnt/beta-catenin signaling pathway plays an important role in hepatocellular carcinoma development. | MicroRNA-504 functions as a tumor suppressor in hepatocellular carcinoma through inhibiting Frizzled-7-mediated-Wnt/β-catenin signaling.
Quan H, Li B, Yang J. | 12/29/2018 |
| Wnt2B co-operates with Frizzled7 to mediate mesenchymal to epithelial transition in colorectal cancer. | Wnt is necessary for mesenchymal to epithelial transition in colorectal cancer cells.
Schwab RHM, Amin N, Flanagan DJ, Johanson TM, Phesse TJ, Vincan E. | 11/10/2018 |