| BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification. | BAP1 Loss Is Associated with Higher ASS1 Expression in Epithelioid Mesothelioma: Implications for Therapeutic Stratification.
Barnett SE, Kenyani J, Tripari M, Butt Z, Grosman R, Querques F, Shaw L, Silva LC, Goate Z, Marciniak SJ, Rassl DM, Jackson R, Lian LY, Szlosarek PW, Sacco JJ, Coulson JM., Free PMC Article | 05/4/2023 |
| CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption. | CUX2, BRAP and ALDH2 are associated with metabolic traits in people with excessive alcohol consumption.
Chen IC, Kuo PH, Yang AC, Tsai SJ, Liu TH, Liu HJ, Lan TH, Chen HM, Huang HN, Chung RH, Liu YL., Free PMC Article | 03/20/2021 |
| Potential mechanisms underlying the association between single nucleotide polymorphism (BRAP and ALDH2) and hypertension among elderly Japanese population. | Potential mechanisms underlying the association between single nucleotide polymorphism (BRAP and ALDH2) and hypertension among elderly Japanese population.
Shimizu Y, Arima K, Noguchi Y, Kawashiri SY, Yamanashi H, Tamai M, Nagata Y, Maeda T., Free PMC Article | 01/9/2021 |
| BRCA1-associated protein inhibits glioma cell proliferation and migration and glioma stem cell self-renewal via the TGF-beta/PI3K/AKT/mTOR signalling pathway. | BRCA1-associated protein inhibits glioma cell proliferation and migration and glioma stem cell self-renewal via the TGF-β/PI3K/AKT/mTOR signalling pathway.
Wang B, Cao C, Liu X, He X, Zhuang H, Wang D, Chen B. | 12/12/2020 |
| Mutation in BRAP gene is associated with childhood pulmonary arterial hypertension. | Role of BRCA1-associated protein (BRAP) variant in childhood pulmonary arterial hypertension.
Chida-Nagai A, Shintani M, Sato H, Nakayama T, Nii M, Akagawa H, Furukawa T, Rana A, Furutani Y, Inai K, Nonoyama S, Nakanishi T., Free PMC Article | 11/16/2019 |
| Average dietary energy in lunch, BRAP SNP rs3782886, and GHRL SNP rs696217 were associated with obesity, and BRAP rs3782886 was associated with other metabolic abnormalities | Effect of dietary energy and polymorphisms in BRAP and GHRL on obesity and metabolic traits.
Imaizumi T, Ando M, Nakatochi M, Yasuda Y, Honda H, Kuwatsuka Y, Kato S, Kondo T, Iwata M, Nakashima T, Yasui H, Takamatsu H, Okajima H, Yoshida Y, Maruyama S. | 04/27/2019 |
| Six polymorphisms (rs12229654 at 12q24.1, rs671 of ALDH2, rs11066015 of ACAD10, rs2074356 and rs11066280 of HECTD4, and rs3782886 of BRAP) were found to be associated with both systolic and diastolic blood pressure, with those at 12q24.1 or in ACAD10 or BRAP being novel determinants of blood pressure in Japanese. | Identification of polymorphisms in 12q24.1, ACAD10, and BRAP as novel genetic determinants of blood pressure in Japanese by exome-wide association studies.
Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M., Free PMC Article | 05/5/2018 |
| IMPACT data were consistent with increased risks of onset among BRCA1 and BRCA2 mutation carriers | Screening Men at Increased Risk for Prostate Cancer Diagnosis: Model Estimates of Benefits and Harms.
Gulati R, Cheng HH, Lange PH, Nelson PS, Etzioni R., Free PMC Article | 01/27/2018 |
| Expression of BRAP is increased in esophageal squamous cell carcinoma samples compared with non-tumor esophageal tissues; increased expression correlates with reduced patient survival time and promotes metastasis of xenograft tumors in mice. | BRCA1-Associated Protein Increases Invasiveness of Esophageal Squamous Cell Carcinoma.
Zhao Y, Wei L, Shao M, Huang X, Chang J, Zheng J, Chu J, Cui Q, Peng L, Luo Y, Tan W, Tan W, Lin D, Wu C. | 11/18/2017 |
| Together the results indicate for the first time that BRAP2 may play an important NRNI role in germ cells of the testis, with an additional, scaffold/structural role in mature spermatozoa. | Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.
Fatima S, Wagstaff KM, Loveland KL, Jans DA., Free PMC Article | 03/26/2016 |
| BRAP gene may confer vulnerability for schizophrenia in Han Chinese population. | A two-stage association study suggests BRAP as a susceptibility gene for schizophrenia.
Zhang F, Liu C, Xu Y, Qi G, Yuan G, Cheng Z, Wang J, Wang G, Wang Z, Zhu W, Zhou Z, Zhao X, Tian L, Jin C, Yuan J, Zhang G, Chen Y, Wang L, Lu T, Yan H, Ruan Y, Yue W, Zhang D., Free PMC Article | 09/27/2014 |
| ectopic expression of BRAP2 inhibits nuclear localization of HMG20A and NuMA1, and prevents nuclear envelope accumulation of SYNE2. | The BRCA1-binding protein BRAP2 can act as a cytoplasmic retention factor for nuclear and nuclear envelope-localizing testicular proteins.
Davies RG, Wagstaff KM, McLaughlin EA, Loveland KL, Jans DA. | 03/1/2014 |
| genetic association studies in population of Chinese Han young adults in Beijing: Data suggest that 2 SNPs in BRAP (rs11066001; rs3782886) are associated with decreased risk of metabolic syndrome in this population. | The single nucleotide polymorphisms in BRAP decrease the risk of metabolic syndrome in a Chinese young adult population.
Wu L, Xi B, Hou D, Zhao X, Liu J, Cheng H, Shen Y, Wang X, Mi J. | 10/26/2013 |
| BAP1 expression closely correlates with age, clinical stage, pathologic differentiation and histological type in colorectal cancer (CRC). BAP1 may serve as a novel prognostic biomarker for CRC. | Prognostic significance of BRCA1-associated protein 1 in colorectal cancer.
Tang J, Xi S, Wang G, Wang B, Yan S, Wu Y, Sang Y, Wu W, Zhang R, Kang T. | 10/26/2013 |
| Brap2 regulates temporal control of NF-kappaB localization mediated by inflammatory response. | Brap2 regulates temporal control of NF-κB localization mediated by inflammatory response.
Takashima O, Tsuruta F, Kigoshi Y, Nakamura S, Kim J, Katoh MC, Fukuda T, Irie K, Chiba T., Free PMC Article | 10/19/2013 |
| The BRAP polymorphism may not play an important role in ischemic stroke in the Taiwanese population. | Lack of association between a functional variant of the BRCA-1 related associated protein (BRAP) gene and ischemic stroke.
Liao YC, Lin HF, Guo YC, Chen CH, Huang ZZ, Juo SH, Lin RT., Free PMC Article | 04/13/2013 |
| The dominant effect of prolonged USP15 depletion upon signal amplitude is due to a decrease in CRAF levels while allowing for the possibility that USP15 may also function to dampen MAPK signaling through direct stabilization of BRAP. | Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.
Hayes SD, Liu H, MacDonald E, Sanderson CM, Coulson JM, Clague MJ, Urbé S., Free PMC Article | 02/16/2013 |
| ANRIL on 9p21 and BRAP were both associated with ankle brachial index in a Taiwanese population. | Additive effect of ANRIL and BRAP polymorphisms on ankle-brachial index in a Taiwanese population.
Tsai PC, Liao YC, Lin TH, Hsi E, Yang YH, Juo SH. | 06/2/2012 |
| Several BRCA1 mutations were observed in Pakistani breast cancer patients with moderate family history. | BRCA1 status in Pakistani breast cancer patients with moderate family history.
Moatter T, Aban M, Khan S, Azam I, Pervez S. | 04/7/2012 |
| Data show that BRAP conferred a risk for carotid plaque and intima-medial thickness. | BRAP Activates Inflammatory Cascades and Increases the Risk for Carotid Atherosclerosis.
Liao YC, Wang YS, Guo YC, Ozaki K, Tanaka T, Lin HF, Chang MH, Chen KC, Yu ML, Sheu SH, Juo SH., Free PMC Article | 03/31/2012 |
| BRAP gene is associated with the extent of coronary atherosclerosis and has a synergistic effect with diabetes on the occurrence of significant CAD in the Chinese population | Synergistic effect between BRAP polymorphism and diabetes on the extent of coronary atherosclerosis in the Chinese population.
Hsu PC, Lin TH, Su HM, Juo SH, Lai WT, Sheu SH. | 03/3/2012 |
| our approach, which is applicable to any set of interval scale traits that is heritable and exhibits evidence of phenotypic clustering, identified three new loci in or near APOC1, BRAP, and PLCG1, which were associated with multiple phenotype domains. | A phenomics-based strategy identifies loci on APOC1, BRAP, and PLCG1 associated with metabolic syndrome phenotype domains.
Avery CL, He Q, North KE, Ambite JL, Boerwinkle E, Fornage M, Hindorff LA, Kooperberg C, Meigs JB, Pankow JS, Pendergrass SA, Psaty BM, Ritchie MD, Rotter JI, Taylor KD, Wilkens LR, Heiss G, Lin DY., Free PMC Article | 02/11/2012 |
| Polymorphism of 270 A > G in BRAP is Associated with Lower Ankle-Brachial Index and peripheral artery disease. | Polymorphism of 270 A > G in BRAP is Associated with Lower Ankle-Brachial Index in a Taiwanese Population.
Tsai PC, Lin TH, Hsu PC, Wang YS, Liao YC, Juo SH. | 10/1/2011 |
| All results are consistent with BRAP2 being a novel, phosphorylation-regulated negative regulator of nuclear import, with potential as an antiviral agent. | The BRCA-1 binding protein BRAP2 is a novel, negative regulator of nuclear import of viral proteins, dependent on phosphorylation flanking the nuclear localization signal.
Fulcher AJ, Roth DM, Fatima S, Alvisi G, Jans DA. | 05/31/2010 |
| Data indicate that one SNP in BRAP showed(rs11066001) a significant association in allele frequency distribution with CAD in both the Japanese and Korean populations. | Validation of eight genetic risk factors in East Asian populations replicated the association of BRAP with coronary artery disease.
Hinohara K, Ohtani H, Nakajima T, Sasaoka T, Sawabe M, Lee BS, Ban J, Park JE, Izumi T, Kimura A. | 03/1/2010 |