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    RBM10 RNA binding motif protein 10 [ Homo sapiens (human) ]

    Gene ID: 8241, updated on 14-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    RBM10 C761Y mutation induced oncogenic ASPM isoforms and regulated beta-catenin signaling in cholangiocarcinoma.

    RBM10 C761Y mutation induced oncogenic ASPM isoforms and regulated β-catenin signaling in cholangiocarcinoma.
    Chang J, Zhang Y, Zhou T, Qiao Q, Shan J, Chen Y, Jiang W, Wang Y, Liu S, Wang Y, Yu Y, Li C, Li X., Free PMC Article

    04/12/2024
    RBM10 regulates the tumorigenic potential of human cancer cells by modulating PPM1B and YBX1 activities.

    RBM10 regulates the tumorigenic potential of human cancer cells by modulating PPM1B and YBX1 activities.
    Li Y, Wei D, Chen Z, Chen Y, Deng Y, Li M, Zhao Y, Niu K.

    02/21/2024
    An RBM10 and NF-kappaB interacting host lncRNA promotes JEV replication and neuronal cell death.

    An RBM10 and NF-κB interacting host lncRNA promotes JEV replication and neuronal cell death.
    Tripathi S, Sengar S, Shree B, Mohapatra S, Basu A, Sharma V., Free PMC Article

    01/3/2024
    RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5.

    RNA-binding motif protein 10 inactivates c-Myc by partnering with ribosomal proteins uL18 and uL5.
    Lee H, Jung JH, Ko HM, Park H, Segall AM, Sheffmaker RL, Wang J, Frey WD, Pham N, Wang Y, Zhang Y, Jackson JG, Zeng SX, Lu H., Free PMC Article

    12/5/2023
    RBM10 recruits METTL3 to induce N6-methyladenosine-MALAT1-dependent modification, inhibiting the invasion and migration of NSCLC.

    RBM10 recruits METTL3 to induce N6-methyladenosine-MALAT1-dependent modification, inhibiting the invasion and migration of NSCLC.
    Cao Y, Di X, Cong S, Tian C, Wang Y, Jin X, Zhao M, Zhou X, Li R, Wang K.

    02/4/2023
    Lycorine upregulates the expression of RMB10, promotes apoptosis and inhibits the proliferation and migration of cervical cancer cells.

    Lycorine upregulates the expression of RMB10, promotes apoptosis and inhibits the proliferation and migration of cervical cancer cells.
    Li Z, Zhou Q, Liu X, Li Y, Fan X, Liu G., Free PMC Article

    11/19/2022
    Phenotypic spectrum of the RBM10-mediated intellectual disability and congenital malformation syndrome beyond classic TARP syndrome features.

    Phenotypic spectrum of the RBM10-mediated intellectual disability and congenital malformation syndrome beyond classic TARP syndrome features.
    Kumps C, D'haenens E, Vergult S, Leus J, van Coster R, Jansen A, Devriendt K, Oostra A, Vanakker OM.

    01/1/2022
    The role of RBM10 mutations in the development, treatment, and prognosis of lung adenocarcinoma.

    The role of RBM10 mutations in the development, treatment, and prognosis of lung adenocarcinoma.
    Li Z, Xue Q, Xu J, Zhang P, Ding B., Free PMC Article

    12/11/2021
    Sequestration of RBM10 in Nuclear Bodies: Targeting Sequences and Biological Significance.

    Sequestration of RBM10 in Nuclear Bodies: Targeting Sequences and Biological Significance.
    Wang LY, Xiao SJ, Kunimoto H, Tokunaga K, Kojima H, Kimura M, Yamamoto T, Yamamoto N, Zhao H, Nishio K, Tani T, Nakajima K, Sunami K, Inoue A., Free PMC Article

    10/30/2021
    Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association.

    Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association.
    Koshre GR, Shaji F, Mohanan NK, Mohan N, Ali J, Laishram RS., Free PMC Article

    10/23/2021
    A novel missense variant in RBM10 can cause a mild form of TARP syndrome with developmental delay and dysmorphic features.

    A novel missense variant in RBM10 can cause a mild form of TARP syndrome with developmental delay and dysmorphic features.
    Imagawa E, Konuma T, Cork EE, Diaz GA, Oishi K.

    08/21/2021
    RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H.

    RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H.
    Zhang S, Bao Y, Shen X, Pan Y, Sun Y, Xiao M, Chen K, Wei H, Zuo J, Saffen D, Zong WX, Sun Y, Wang Z, Wang Y., Free PMC Article

    08/7/2021
    RBM10: Structure, functions, and associated diseases.

    RBM10: Structure, functions, and associated diseases.
    Inoue A., Free PMC Article

    04/24/2021
    Protective effect of the RNA-binding protein RBM10 in hepatocellular carcinoma.

    Protective effect of the RNA-binding protein RBM10 in hepatocellular carcinoma.
    Zhao Z, Li J, Shen F.

    04/24/2021
    RBM10, a New Regulator of p53.

    RBM10, a New Regulator of p53.
    Jung JH, Lee H, Zeng SX, Lu H., Free PMC Article

    03/28/2021
    RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.

    RNA-binding motif protein 10 induces apoptosis and suppresses proliferation by activating p53.
    Jung JH, Lee H, Cao B, Liao P, Zeng SX, Lu H., Free PMC Article

    11/28/2020
    Dengue virus targets RBM10 deregulating host cell splicing and innate immune response.

    Dengue virus targets RBM10 deregulating host cell splicing and innate immune response.
    Pozzi B, Bragado L, Mammi P, Torti MF, Gaioli N, Gebhard LG, García Solá ME, Vaz-Drago R, Iglesias NG, García CC, Gamarnik AV, Srebrow A., Free PMC Article

    09/12/2020
    RBM10 regulates centriole duplication in HepG2 cells by ectopically assembling PLK4-STIL complexes in the nucleus.

    RBM10 regulates centriole duplication in HepG2 cells by ectopically assembling PLK4-STIL complexes in the nucleus.
    Kunimoto H, Inoue A, Kojima H, Yang J, Zhao H, Tsuruta D, Nakajima K.

    09/12/2020
    RBM10 reduces the phosphorylation of CREB via the AKT signalling pathway, suggesting that RBM10 exhibits its effect on lung adenocarcinoma cell proliferation via the RAP1/AKT/CREB signalling pathway.

    RBM10 inhibits cell proliferation of lung adenocarcinoma via RAP1/AKT/CREB signalling pathway.
    Jin X, Di X, Wang R, Ma H, Tian C, Zhao M, Cong S, Liu J, Li R, Wang K., Free PMC Article

    08/1/2020
    The present study suggests that the carcinogenesis of RBM10-TFE3 RCC in some, but not all, patients may be associated with chronic kidney disease.

    RBM10-TFE3 renal cell carcinoma characterised by paracentric inversion with consistent closely split signals in break-apart fluorescence in-situ hybridisation: study of 10 cases and a literature review.
    Kato I, Furuya M, Baba M, Kameda Y, Yasuda M, Nishimoto K, Oyama M, Yamasaki T, Ogawa O, Niino H, Nakaigawa N, Yano Y, Sakamoto K, Urata Y, Mikami K, Yamasaki S, Tanaka R, Takagi T, Kondo T, Nagashima Y.

    01/25/2020
    RBM10 binds the pre-mRNA UTR, assembles the Star-PAP complex, and guides this complex specifically to mRNAs encoding regulators of cardiac hypertrophy.

    A Splicing-Independent Function of RBM10 Controls Specific 3' UTR Processing to Regulate Cardiac Hypertrophy.
    Mohan N, Kumar V, Kandala DT, Kartha CC, Laishram RS.

    12/14/2019
    we found that RBM10 activated key proliferative signaling pathways [such as the epidermal growth factor receptor (EGFR), mitogenactivated protein kinase (MAPK) and phosphoinositide 3kinase (PI3K)AKT pathways] and inhibited apoptotic pathways. In addition, we demonstrated that a high expression of RBM10 protein in patient tissue samples was associated with a shorter overall survival time and a poor prognosis

    Functional role of RBM10 in lung adenocarcinoma proliferation.
    Sun X, Jia M, Sun W, Feng L, Gu C, Wu T., Free PMC Article

    04/6/2019
    RBM10 acts as a tumor suppressor in osteosarcoma. This could enable to define a new strategy for diagnosis and treatment of patients with osteosarcoma.

    Overexpression of RBM10 induces osteosarcoma cell apoptosis and inhibits cell proliferation and migration.
    Han LP, Wang CP, Han SL.

    02/16/2019
    RBM10: Harmful or helpful-many factors to consider.

    RBM10: Harmful or helpful-many factors to consider.
    Loiselle JJ, Sutherland LC., Free PMC Article

    12/22/2018
    RBM10 mutations contribute to lung adenocarcinoma pathogenesis.

    Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing.
    Zhao J, Sun Y, Huang Y, Song F, Huang Z, Bao Y, Zuo J, Saffen D, Shao Z, Liu W, Wang Y., Free PMC Article

    10/20/2018
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