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    NRIP1 nuclear receptor interacting protein 1 [ Homo sapiens (human) ]

    Gene ID: 8204, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells.

    RIP140 regulates transcription factor HES1 oscillatory expression and mitogenic activity in colon cancer cells.
    Sfeir N, Kajdan M, Jalaguier S, Bonnet S, Teyssier C, Pyrdziak S, Yuan R, Bousquet E, Maraver A, Bernex F, Pirot N, Boissière-Michot F, Castet-Nicolas A, Lapierre M, Cavaillès V., Free PMC Article

    06/18/2024
    NRIP1 regulates cell proliferation in lung adenocarcinoma cells.

    NRIP1 regulates cell proliferation in lung adenocarcinoma cells.
    Watanabe F, Sato S, Hirose T, Endo M, Endo A, Ito H, Ohba K, Mori T, Takahashi K.

    03/5/2024
    CircNRIP1 promotes proliferation, migration and phenotypic switch of Ang II-induced HA-VSMCs by increasing CXCL5 mRNA stability via recruiting IGF2BP1.

    CircNRIP1 promotes proliferation, migration and phenotypic switch of Ang II-induced HA-VSMCs by increasing CXCL5 mRNA stability via recruiting IGF2BP1.
    Cao X, Fang H, Zhou L.

    02/6/2024
    Circular RNA nuclear receptor interacting protein 1 promoted biliary tract cancer epithelial-mesenchymal transition and stemness by regulating the miR-515-5p/AKT2 axis and PI3K/AKT/mTOR signaling pathway.

    Circular RNA nuclear receptor interacting protein 1 promoted biliary tract cancer epithelial-mesenchymal transition and stemness by regulating the miR-515-5p/AKT2 axis and PI3K/AKT/mTOR signaling pathway.
    Gao X, Yu S, Liu S, Zhang S, Sha X, Sun D, Jiang X.

    10/11/2023
    The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.

    The retinoic acid receptor co-factor NRIP1 is uniquely upregulated and represents a therapeutic target in acute myeloid leukemia with chromosome 3q rearrangements.
    Grasedieck S, Cabantog A, MacPhee L, Im J, Ruess C, Demir B, Sperb N, Rücker FG, Döhner K, Herold T, Pollack JR, Bullinger L, Rouhi A, Kuchenbauer F., Free PMC Article

    08/6/2022
    Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines.

    Receptor-Interacting Protein 140 Enhanced Temozolomide-Induced Cellular Apoptosis Through Regulation of E2F1 in Human Glioma Cell Lines.
    Tsai HC, Wei KC, Chen PY, Huang CY, Chen KT, Lin YJ, Cheng HW, Huang CH, Wang HT.

    05/28/2022
    RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53.

    RIP140 inhibits glycolysis-dependent proliferation of breast cancer cells by regulating GLUT3 expression through transcriptional crosstalk between hypoxia induced factor and p53.
    Jacquier V, Gitenay D, Fritsch S, Bonnet S, Győrffy B, Jalaguier S, Linares LK, Cavaillès V, Teyssier C., Free PMC Article

    05/14/2022
    A truncating NRIP1 variant in an Arabic family with congenital anomalies of the kidneys and urinary tract.

    A truncating NRIP1 variant in an Arabic family with congenital anomalies of the kidneys and urinary tract.
    Zheng B, Wang C, Seltzsam S, Schneider S, Schierbaum L, Wu W, Dai R, Connaughton DM, Nakayama M, Mann N, Bauer SB, Awad HS, Eid LA, Tasic V, Shril S, Hildebrandt F., Free PMC Article

    04/23/2022
    Knockdown of receptor interacting protein 140 (RIP140) alleviated lipopolysaccharide-induced inflammation, apoptosis and permeability in pulmonary microvascular endothelial cells by regulating C-terminal binding protein 2 (CTBP2).

    Knockdown of receptor interacting protein 140 (RIP140) alleviated lipopolysaccharide-induced inflammation, apoptosis and permeability in pulmonary microvascular endothelial cells by regulating C-terminal binding protein 2 (CTBP2).
    Wang Q, Wu Q., Free PMC Article

    04/2/2022
    NRIP1 is activated by C-JUN/C-FOS and activates the expression of PGR, ESR1 and CCND1 in luminal A breast cancer.

    NRIP1 is activated by C-JUN/C-FOS and activates the expression of PGR, ESR1 and CCND1 in luminal A breast cancer.
    Binato R, Corrêa S, Panis C, Ferreira G, Petrone I, da Costa IR, Abdelhay E., Free PMC Article

    01/29/2022
    Knockdown of circNRIP1 sensitizes colorectal cancer to 5FU via sponging miR5323p.

    Knockdown of circNRIP1 sensitizes colorectal cancer to 5‑FU via sponging miR‑532‑3p.
    Liu F, Li R, Zhang R, He M, Zhang Y., Free PMC Article

    01/8/2022
    The Expression of NRIP1 and LCOR in Endometrioid Endometrial Cancer.

    The Expression of NRIP1 and LCOR in Endometrioid Endometrial Cancer.
    Flindris S, Katsoulas N, Goussia A, Lazaris AC, Navrozoglou I, Paschopoulos M, Thymara I., Free PMC Article

    08/28/2021
    The bivariate NRIP1/ZEB2 RNA marker permits non-invasive presymptomatic screening of pre-eclampsia.

    The bivariate NRIP1/ZEB2 RNA marker permits non-invasive presymptomatic screening of pre-eclampsia.
    Manders V, Visser A, Keijser R, Min N, Poutsma A, Mulders J, van den Berkmortel T, Hortensius M, Jongejan A, Pajkrt E, Sistermans EA, Sie D, Best MG, Würdinger T, de Boer M, Afink G, Oudejans C., Free PMC Article

    05/1/2021
    New insights into the genetic basis of premature ovarian insufficiency: Novel causative variants and candidate genes revealed by genomic sequencing.

    New insights into the genetic basis of premature ovarian insufficiency: Novel causative variants and candidate genes revealed by genomic sequencing.
    Jaillard S, Bell K, Akloul L, Walton K, McElreavy K, Stocker WA, Beaumont M, Harrisson C, Jääskeläinen T, Palvimo JJ, Robevska G, Launay E, Satié AP, Listyasari N, Bendavid C, Sreenivasan R, Duros S, van den Bergen J, Henry C, Domin-Bernhard M, Cornevin L, Dejucq-Rainsford N, Belaud-Rotureau MA, Odent S, Ayers KL, Ravel C, Tucker EJ, Sinclair AH.

    11/28/2020
    NRIP is essential to maintain sarcomere structure and mitochondrial/contractile function in cardiomyocytes.

    Deficiency of nuclear receptor interaction protein leads to cardiomyopathy by disrupting sarcomere structure and mitochondrial respiration.
    Yang KC, Chuang KW, Yen WS, Lin SY, Chen HH, Chang SW, Lin YS, Wu WL, Tsao YP, Chen WP, Chen SL.

    07/11/2020
    Nuclear and cytoplasmic RIP140 expression increases significantly with higher grading of cervical intraepithelial neoplasia underlining its potential role in the development of pre-cancerous lesions.

    Regulation of LCoR and RIP140 expression in cervical intraepithelial neoplasia and correlation with CIN progression and dedifferentiation.
    Vogelsang TLR, Schmoeckel E, Kuhn C, Blankenstein T, Temelkov M, Heidegger H, Kolben TM, Kolben T, Mahner S, Mayr D, Jeschke U, Vattai A., Free PMC Article

    06/20/2020
    SUV39H2 elevation contributes to the progression of nasopharyngeal carcinoma via regulation of NRIP1

    Elevated SUV39H2 attributes to the progression of nasopharyngeal carcinoma via regulation of NRIP1.
    Chao C, You J, Li H, Xue H, Tan X.

    11/16/2019
    MicroRNA-548-3p and MicroRNA-576-5p enhance the migration and invasion of esophageal squamous cell carcinoma cells via NRIP1 down-regulation

    MicroRNA-548-3p and MicroRNA-576-5p enhance the migration and invasion of esophageal squamous cell carcinoma cells via NRIP1 down-regulation.
    Ni XF, Zhao LH, Li G, Hou M, Su M, Zou CL, Deng X.

    07/6/2019
    Disruption of a nuclear co-repressor of catabolism, the Nrip1 gene, in white adipocytes enhanced adipocyte browning with a marked increase of uncoupling protein 1 expression.

    CRISPR-delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure.
    Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline RH, Kim JK, Czech MP., Free PMC Article

    06/1/2019
    this preliminary report indicates that the ERbeta/RIP140 signaling is altered in unifocal breast cancers and correlated with patient outcome.

    Prognostic relevance of RIP140 and ERβ expression in unifocal versus multifocal breast cancers: a preliminary report.
    Müller K, Sixou S, Kuhn C, Jalaguier S, Mayr D, Ditsch N, Weissenbacher T, Harbeck N, Mahner S, Cavaillès V, Jeschke U., Free PMC Article

    05/4/2019
    Data suggests that NRIP1 is overexpressed both in skin and PBMCs of psoriasis patients and may be involved in the abnormal proliferation and apoptosis of keratinocytes.

    Overexpression and potential roles of NRIP1 in psoriasis.
    Luan C, Chen X, Hu Y, Hao Z, Osland JM, Chen X, Gerber SD, Chen M, Gu H, Yuan R., Free PMC Article

    03/24/2018
    In skeletal muscle, imposed rest increased NRIP1 expression by 80%, and strength training increased expression by 25% compared to baseline. Following rest, NRIP1 expression became sensitive to insulin stimulation. After re-training, NRIP1 expression decreased. Interactome analysis showed significant proximity of NRIP1 interacting partners to the obesity network/module.

    Regulation of Nuclear Receptor Interacting Protein 1 (NRIP1) Gene Expression in Response to Weight Loss and Exercise in Humans.
    De Marinis Y, Sun J, Bompada P, Domènech Omella J, Luan C, Halu A, Renström E, Sharma A, Ridderstråle M.

    02/10/2018
    Taken together, these results provide new insights into the mechanism of action of LCoR and RIP140 and highlight their strong interplay for the control of gene expression and cell proliferation in breast cancer cells.

    Complex regulation of LCoR signaling in breast cancer cells.
    Jalaguier S, Teyssier C, Nait Achour T, Lucas A, Bonnet S, Rodriguez C, Elarouci N, Lapierre M, Cavaillès V., Free PMC Article

    10/14/2017
    Study found low expression level of RIP140 in tumor-associated macrophages (TAM) of hepatocellular carcinoma (HCC) tissues and demonstrated that RIP140 expression in plays a role in the growth of hepatoma cells.

    Overexpression of RIP140 suppresses the malignant potential of hepatocellular carcinoma by inhibiting NF‑κB‑mediated alternative polarization of macrophages.
    Hu YC, Yi ZJ, Zhou Y, Li PZ, Liu ZJ, Duan SG, Gong JP.

    05/13/2017
    results indicated that there was a significant association between migraine and gene-gene interaction among the CYP19A1, FSHR, ESR1 and NRIP1.

    Contribution of polymorphisms in ESR1, ESR2, FSHR, CYP19A1, SHBG, and NRIP1 genes to migraine susceptibility in Turkish population.
    CoŞkun S, Yůcel Y, Çim A, Cengiz B, Oztuzcu S, Varol S, Özdemir HH, Uzar E.

    12/31/2016
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