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    Tlr9 toll-like receptor 9 [ Mus musculus (house mouse) ]

    Gene ID: 81897, updated on 11-Jul-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Triad3A-Mediated K48-Linked ubiquitination and degradation of TLR9 impairs mitochondrial bioenergetics and exacerbates diabetic cardiomyopathy.

    Triad3A-Mediated K48-Linked ubiquitination and degradation of TLR9 impairs mitochondrial bioenergetics and exacerbates diabetic cardiomyopathy.
    Kong C, Guo Z, Liu F, Tang N, Wang M, Yang D, Li C, Yang Z, Ma Y, Wang P, Tang Q.

    07/11/2024
    Activation of TLR9 signaling suppresses the immunomodulating functions of CD55[lo] fibroblastic reticular cells during bacterial peritonitis.

    Activation of TLR9 signaling suppresses the immunomodulating functions of CD55(lo) fibroblastic reticular cells during bacterial peritonitis.
    Jiang T, Li Y, Huang X, Jayakumar P, Billiar TR, Deng M., Free PMC Article

    07/7/2024
    The Role of TLR7 and TLR9 in the Pathogenesis of Systemic Sclerosis.

    The Role of TLR7 and TLR9 in the Pathogenesis of Systemic Sclerosis.
    Wang C, Oishi K, Kobayashi T, Fujii K, Horii M, Fushida N, Kitano T, Maeda S, Ikawa Y, Komuro A, Hamaguchi Y, Matsushita T., Free PMC Article

    07/3/2024
    Epstein-Barr Virus DNA Exacerbates Arthritis in a Mouse Model via Toll-like Receptor 9.

    Epstein-Barr Virus DNA Exacerbates Arthritis in a Mouse Model via Toll-like Receptor 9.
    Sherri N, Assaf R, Bitar ER, Znait S, Borghol AH, Kassem A, Rahal EA., Free PMC Article

    07/3/2024
    Nucleic acid sensing Toll-like receptors 3 and 9 play complementary roles in the development of bacteremia after nasal colonization associated with influenza co-infection.

    Nucleic acid sensing Toll-like receptors 3 and 9 play complementary roles in the development of bacteremia after nasal colonization associated with influenza co-infection.
    Nanushaj D, Kono M, Sakatani H, Murakami D, Hotomi M., Free PMC Article

    07/2/2024
    Toll-like receptor 9 signaling is associated with immune responses to Trypanosoma brucei infection.

    Toll-like receptor 9 signaling is associated with immune responses to Trypanosoma brucei infection.
    Yu L, Li Q, Jiang N, Fan R, Zhang N, Zhang Y, Sun W, Chen R, Feng Y, Sang X, Chen Q.

    06/10/2024
    Tlr9 deficiency in B cells leads to obesity by promoting inflammation and gut dysbiosis.

    Tlr9 deficiency in B cells leads to obesity by promoting inflammation and gut dysbiosis.
    Wang P, Yang X, Zhang L, Sha S, Huang J, Peng J, Gu J, Pearson JA, Hu Y, Zhao H, Wong FS, Wang Q, Wen L., Free PMC Article

    05/24/2024
    Motor, Cognitive, and Behavioral Impairment in TLR3 and TLR9 Deficient Male Mice: Insights into the Non-Immunological Roles of Toll-Like Receptors.

    Motor, Cognitive, and Behavioral Impairment in TLR3 and TLR9 Deficient Male Mice: Insights into the Non-Immunological Roles of Toll-Like Receptors.
    Vargas-Calderón H, Ortega-Robles E, Rocha L, Yu P, Arias-Carrión O.

    04/25/2024
    Formation of memory assemblies through the DNA-sensing TLR9 pathway.

    Formation of memory assemblies through the DNA-sensing TLR9 pathway.
    Jovasevic V, Wood EM, Cicvaric A, Zhang H, Petrovic Z, Carboncino A, Parker KK, Bassett TE, Moltesen M, Yamawaki N, Login H, Kalucka J, Sananbenesi F, Zhang X, Fischer A, Radulovic J., Free PMC Article

    04/6/2024
    TLR9 Knockdown Alleviates Sepsis via Disruption of MyD88/NF-kappaB Pathway Activation.

    TLR9 Knockdown Alleviates Sepsis via Disruption of MyD88/NF-κB Pathway Activation.
    Li L, Jiang L, Mao S, Ye J.

    03/7/2024
    TLR9-independent CD8[+] T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.

    TLR9-independent CD8(+) T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.
    Kumar SRP, Biswas M, Cao D, Arisa S, Muñoz-Melero M, Lam AK, Piñeros AR, Kapur R, Kaisho T, Kaufman RJ, Xiao W, Shayakhmetov DM, Terhorst C, de Jong YP, Herzog RW.,

    02/16/2024
    TLR9 regulates the autophagy-lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6-cGAS-STING pathway.

    TLR9 regulates the autophagy-lysosome pathway to promote dendritic cell maturation and activation by activating the TRAF6-cGAS-STING pathway.
    Liu Y, Wei FZ, Zhan YW, Wang R, Mo BY, Lin SD.

    12/27/2023
    Activation of cell-free mtDNA-TLR9 signaling mediates chronic stress-induced social behavior deficits.

    Activation of cell-free mtDNA-TLR9 signaling mediates chronic stress-induced social behavior deficits.
    Tripathi A, Bartosh A, Whitehead C, Pillai A., Free PMC Article

    12/22/2023
    TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance.

    TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance.
    Çakan E, Ah Kioon MD, Garcia-Carmona Y, Glauzy S, Oliver D, Yamakawa N, Vega Loza A, Du Y, Schickel JN, Boeckers JM, Yang C, Baldo A, Ivashkiv LB, Young RM, Staudt LM, Moody KL, Nündel K, Marshak-Rothstein A, van der Made CI, Hoischen A, Hayward A, Rossato M, Radstake TRDJ, Cunningham-Rundles C, Ryu C, Herzog EL, Barrat FJ, Meffre E., Free PMC Article

    10/2/2023
    MTMR3 risk alleles enhance Toll Like Receptor 9-induced IgA immunity in IgA nephropathy.

    MTMR3 risk alleles enhance Toll Like Receptor 9-induced IgA immunity in IgA nephropathy.
    Wang YN, Gan T, Qu S, Xu LL, Hu Y, Liu LJ, Shi SF, Lv JC, Tsoi LC, Patrick MT, He K, Berthier CC, Xu HJ, Zhou XJ, Zhang H.

    08/25/2023
    Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9.

    Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9.
    Gavin AL, Blane TR, Thinnes TC, Gerlt E, Marshak-Rothstein A, Huang D, Nemazee D., Free PMC Article

    08/10/2023
    TLR9 triggers MyD88-independent anti-inflammatory signaling in lupus.

    TLR9 triggers MyD88-independent anti-inflammatory signaling in lupus.
    Zhang S, Cao X.

    03/7/2023
    Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis.

    Toll-like Receptor 9 Induced Dendritic Cell Activation Promotes Anti-Myeloperoxidase Autoimmunity and Glomerulonephritis.
    Ford SL, O'Sullivan KM, Kitching AR, Holdsworth SR, Gan PY, Summers SA., Free PMC Article

    01/28/2023
    Role of Myeloid Cell-Specific TLR9 in Mitochondrial DNA-Induced Lung Inflammation in Mice.

    Role of Myeloid Cell-Specific TLR9 in Mitochondrial DNA-Induced Lung Inflammation in Mice.
    Dimasuay KG, Berg B, Schaunaman N, Chu HW., Free PMC Article

    01/28/2023
    Context-Dependent Roles for Toll-Like Receptors 2 and 9 in the Pathogenesis of Staphylococcus aureus Osteomyelitis.

    Context-Dependent Roles for Toll-Like Receptors 2 and 9 in the Pathogenesis of Staphylococcus aureus Osteomyelitis.
    Petronglo JR, Putnam NE, Ford CA, Cruz-Victorio V, Curry JM, Butrico CE, Fulbright LE, Johnson JR, Peck SH, Fatah SR, Cassat JE., Free PMC Article

    11/26/2022
    TLR9 Mediates Periodontal Aging by Fostering Senescence and Inflammaging.

    TLR9 Mediates Periodontal Aging by Fostering Senescence and Inflammaging.
    Albuquerque-Souza E, Crump KE, Rattanaprukskul K, Li Y, Shelling B, Xia-Juan X, Jiang M, Sahingur SE., Free PMC Article

    11/26/2022
    TLR9 Negatively Regulates Intracellular Bacterial Killing by Pyroptosis in Burkholderia pseudomallei-Infected Mouse Macrophage Cell Line (Raw264.7).

    TLR9 Negatively Regulates Intracellular Bacterial Killing by Pyroptosis in Burkholderia pseudomallei-Infected Mouse Macrophage Cell Line (Raw264.7).
    Pudla M, Sanongkiet S, Ekchariyawat P, Luangjindarat C, Ponpuak M, Utaisincharoen P., Free PMC Article

    11/5/2022
    Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus.

    Genetic dissection of TLR9 reveals complex regulatory and cryptic proinflammatory roles in mouse lupus.
    Leibler C, John S, Elsner RA, Thomas KB, Smita S, Joachim S, Levack RC, Callahan DJ, Gordon RA, Bastacky S, Fukui R, Miyake K, Gingras S, Nickerson KM, Shlomchik MJ., Free PMC Article

    10/15/2022
    Intestinal serotonergic system is modulated by Toll-like receptor 9.

    Intestinal serotonergic system is modulated by Toll-like receptor 9.
    Layunta E, Latorre E, Grasa L, Arruebo MP, Buey B, Alcalde AI, Mesonero JE., Free PMC Article

    08/27/2022
    Anti-tumor immunity by transcriptional synergy between TLR9 and STING activation.

    Anti-tumor immunity by transcriptional synergy between TLR9 and STING activation.
    Temizoz B, Hioki K, Kobari S, Jounai N, Kusakabe T, Lee MSJ, Coban C, Kuroda E, Ishii KJ.

    07/9/2022
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