| Data show that spermiation is actin- and microtubule-based cytoskeletal-dependent event, involving regulatory proteins that modify cytoskeletal organization. | Sperm Release at Spermiation Is Regulated by Changes in the Organization of Actin- and Microtubule-Based Cytoskeletons at the Apical Ectoplasmic Specialization-A Study Using the Adjudin Model.
Li L, Tang EI, Chen H, Lian Q, Ge R, Silvestrini B, Cheng CY., Free PMC Article | 12/23/2017 |
| Data show that spermatid/phagosome transport across the epithelium during spermatogenesis requires the coordination between actin- and microtubule (MT)-based cytoskeletons. | Coordination of Actin- and Microtubule-Based Cytoskeletons Supports Transport of Spermatids and Residual Bodies/Phagosomes During Spermatogenesis in the Rat Testis.
Tang EI, Lee WM, Cheng CY., Free PMC Article | 08/20/2016 |
| Both ZBP1 and HuD bind the zipcode element in rat beta-actin mRNA's 3' UTR. Differences between HuD and ZBP1 were observed in their binding preference to the element. | Different motif requirements for the localization zipcode element of β-actin mRNA binding by HuD and ZBP1.
Kim HH, Lee SJ, Gardiner AS, Perrone-Bizzozero NI, Yoo S., Free PMC Article | 12/19/2015 |
| Thsi study validated the Hprt1, Actb, Mapk6 or B2m and showed that any one or combination of two of them are good reference genes for normalization of mRNA expression in qPCR experiments in the spinal cord and RVM in the CFA model of inflammatory injury. | Validation of four reference genes for quantitative mRNA expression studies in a rat model of inflammatory injury.
Walder RY, Wattiez AS, White SR, Marquez de Prado B, Hamity MV, Hammond DL., Free PMC Article | 03/21/2015 |
| Data indicate that LIM motif-containing protein kinases LIMK1 and LIMK2-dependent acin rearrangement is involved in the development of complete Freund's adjuvant (CFA)-induced inflammatory pain. | LIMK-dependent actin polymerization in primary sensory neurons promotes the development of inflammatory heat hyperalgesia in rats.
Li Y, Hu F, Chen HJ, Du YJ, Xie ZY, Zhang Y, Wang J, Wang Y. | 02/21/2015 |
| Our study demonstrates that gene expression levels of reference genes commonly used in obesity-related studies, such as ACTB or RPS18, are altered by changes in acute or chronic energy status. | Identification of optimal reference genes for RT-qPCR in the rat hypothalamus and intestine for the study of obesity.
Li B, Matter EK, Hoppert HT, Grayson BE, Seeley RJ, Sandoval DA., Free PMC Article | 11/8/2014 |
| Htt and the huntingtin-associated protein 1 (HAP1) are co-localized with the microtubule motor proteins, the KIF5A kinesin and dynein, during dendritic transport of beta-actin mRNA. | Huntingtin mediates dendritic transport of β-actin mRNA in rat neurons.
Ma B, Savas JN, Yu MS, Culver BP, Chao MV, Tanese N., Free PMC Article | 09/14/2013 |
| Axonal translation of beta-actin mRNA supports axon branching and axonal translation of GAP-43 mRNA supports elongating growth. | Axonally synthesized β-actin and GAP-43 proteins support distinct modes of axonal growth.
Donnelly CJ, Park M, Spillane M, Yoo S, Pacheco A, Gomes C, Vuppalanchi D, McDonald M, Kim HH, Merianda TT, Gallo G, Twiss JL., Free PMC Article | 04/27/2013 |
| Findings demonstrate that both acute and chronic Immobilization Stress lead to gene transcriptional changes of beta-actin, APP and MAPK-1. These changes may lead to cognitive deterioration, and the development of Alzheimer disease. | [Acute and chronic stress induced changes in gene transcriptions related to Alzheimer's disease].
Sántha P, Pákáski M, Fazekas O, Szucs S, Fodor EK, Kálmán J Jr, Kálmán S, Szabó G, Janka Z, Kálmán J. | 07/14/2012 |
| we provide new evidence that microtubule-associated protein 2 (MAP2), calcium/calmodulin-dependent protein kinase II (CaMKIIalpha) and beta-actin RNAs localize to dendrites in distinct RNPs, which contain--unexpectedly--very few RNA molecules. | Independent localization of MAP2, CaMKIIα and β-actin RNAs in low copy numbers.
Mikl M, Vendra G, Kiebler MA., Free PMC Article | 01/28/2012 |
| The authors hypothesize a new post-transcriptional mechanism regulating a messenger encoded by nuclear genome for a mitochondrial protein and that Hsp90 and Actin, could represent key players in cytochrome c oxidase subunit IV translation. | Proteins participating to the post-transcriptional regulation of the mitochondrial cytochrome c oxidase subunit IV via elements located in the 3'UTR.
Cannino G, Ferruggia E, Rinaldi AM. | 01/21/2010 |
| The molecular mechanism and function of beta-actin mRNA localization in dendrites of cultured hippocampal neurons was studied; ZBP1 is required for the localization of beta-actin mRNA to dendrites | Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses.
Eom T, Antar LN, Singer RH, Bassell GJ., Free PMC Article | 01/21/2010 |
| extremely high levels of beta-actin mRNA in osteoclasts observed in developing molar tooth germ in the mandibular bone surface | Extremely high expression of beta-actin mRNA in osteoclasts resorbing alveolar bone located at the distal area of the developing molar tooth germ in newborn rats.
Kukita T, Kukita A, Xu L, Toh K, Tang Q, Nomiyama H, Iijima T. | 01/21/2010 |
| Axonal outgrowth seen after the second of two serial axotomies is related to the ability of newly synthesized actin that is already in transit to polymerize in response to the first axotomy. | Increased beta-actin and tubulin polymerization in regrowing axons: relationship to the conditioning lesion effect.
Lund LM, Machado VM, McQuarrie IG. | 01/21/2010 |