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    Vim vimentin [ Rattus norvegicus (Norway rat) ]

    Gene ID: 81818, updated on 18-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Impairment of Assembly of the Vimentin Intermediate Filaments Leads to Suppression of Formation and Maturation of Focal Contacts and Alteration of the Type of Cellular Protrusions.

    Impairment of Assembly of the Vimentin Intermediate Filaments Leads to Suppression of Formation and Maturation of Focal Contacts and Alteration of the Type of Cellular Protrusions.
    Zholudeva AO, Potapov NS, Kozlova EA, Lomakina ME, Alexandrova AY.

    03/14/2024
    The role of vimentin in directional migration of rat fibroblasts.

    The role of vimentin in directional migration of rat fibroblasts.
    Vakhrusheva A, Endzhievskaya S, Zhuikov V, Nekrasova T, Parshina E, Ovsiannikova N, Popov V, Bagrov D, Minin AА, Sokolova OS.

    08/29/2020
    Delayed elevation in spinal astrocytic vimentin corresponds to sustained mechanical hyperalgesia.

    Nerve Root Compression Increases Spinal Astrocytic Vimentin in Parallel With Sustained Pain and Endothelial Vimentin in Association With Spinal Vascular Reestablishment.
    Smith JR, Lee J, Winkelstein BA., Free PMC Article

    06/8/2019
    We labeled brain with ZO1, vimentin, pan-cadherin and angiotensin II type 1 receptors markers which showed a morphologically distinct population of cells at the region of the sulcus medianus organum similar to tanycytes present in the median eminence, a known circumventricular organ.

    Expression of ZO1, vimentin, pan-cadherin and AGTR1 in tanycyte-like cells of the sulcus medianus organum.
    Al-Kaabi M, Hussam F, Al-Marsoummi S, Al-Anbaki A, Al-Salihi A, Al-Aubaidy H.

    11/10/2018
    The present study found that social isolation during adolescence resulted in abnormal locomotor, emotional and cognitive behaviors and increased the expression of GFAP, ANXA2 and VIM in PFC of adult rats.

    Adolescent social isolation affects schizophrenia-like behavior and astrocyte biomarkers in the PFC of adult rats.
    Sun L, Min L, Zhou H, Li M, Shao F, Wang W.

    04/21/2018
    dephosphorylation of MAP2D at Thr256 and Thr259, phosphorylation of vimentin at Ser38 and Ser72, and the resulting enhanced binding of MAP2D to vimentin might contribute to the progesterone synthetic response required for ovulation.

    Dephosphorylation of MAP2D enhances its binding to vimentin in preovulatory ovarian granulosa cells.
    Flynn MP, Fiedler SE, Karlsson AB, Carr DW, Maizels ET, Hunzicker-Dunn M., Free PMC Article

    08/5/2017
    alpha-catulin has a unique function in co-localization with vimentin filaments that contributes to vascular endothelial cells migration via a pathway that may involve ROCK signaling.

    Alpha-Catulin Co-Localizes With Vimentin Intermediate Filaments and Functions in Pulmonary Vascular Endothelial Cell Migration via ROCK.
    Bear MD, Liu T, Abualkhair S, Ghamloush MA, Hill NS, Preston I, Fanburg BL, Kayyali US, Toksoz D.

    05/7/2017
    considering the steroid hormone imbalance in late life period, as well as, the role of this imbalance in prostatic lesion development and progression, the aim of the study herein was to characterize and correlate prolactin, EGFR, alpha-actin and vimentin immunoreactivity in the prostatic epithelium and stroma of elderly rats, following steroid hormone imbalance.

    Prolactin, EGFR, vimentin and α-actin profiles in elderly rat prostate subjected to steroid hormonal imbalance.
    Hetzl AC, Montico F, Kido LA, Cagnon VH.

    03/25/2017
    vimentin may be a novel ligand of IGF1R that promotes axonal growth in a similar manner to IGF1.

    Extracellular vimentin interacts with insulin-like growth factor 1 receptor to promote axonal growth.
    Shigyo M, Kuboyama T, Sawai Y, Tada-Umezaki M, Tohda C., Free PMC Article

    07/30/2016
    In transected spinal cord rats, vimentin knockdown in the scar tissues showed a significant improvement on locomotor function in hindlimbs.

    Vimentin regulates neuroplasticity in transected spinal cord rats associated with micRNA138.
    Qian BJ, You L, Shang FF, Liu J, Dai P, Lin N, He M, Liu R, Zhang Y, Xu Y, Zhang YH, Wang TH.

    03/19/2016
    The increased expression of LP-vimentin-IR cells suggests that changes in cell-cell interactions could play a role in ischemia-induced changes in bladder activity.

    Urinary bladder mucosal responses to ischemia.
    Sunagawa M, Wolf-Johnston A, Nomiya M, Sawada N, Andersson KE, Hisamitsu T, Birder LA., Free PMC Article

    10/17/2015
    Double-immunostaining experiments with antibodies against Stk33 and vimentin showed a striking colocalization of Stk33 and vimentin in the hypothalamus.

    Co-localization of serine/threonine kinase 33 (Stk33) and vimentin in the hypothalamus.
    Brauksiepe B, Baumgarten L, Reuss S, Schmidt ER.

    09/13/2014
    TGFbeta stimulates vimentin production via PI3K-Akt-mTOR signaling, which leads to suppression of ATF4-dependent Ocn transcription and osteoblast differentiation.

    Transforming growth factor β suppresses osteoblast differentiation via the vimentin activating transcription factor 4 (ATF4) axis.
    Lian N, Lin T, Liu W, Wang W, Li L, Sun S, Nyman JS, Yang X., Free PMC Article

    12/29/2012
    We have identified three protein biomarkers (GSN, MYL2, and VIM) that have potential utility in diagnosing the severity of Chagas disease

    Proteome expression and carbonylation changes during Trypanosoma cruzi infection and Chagas disease in rats.
    Wen JJ, Garg NJ., Free PMC Article

    08/11/2012
    vimentin is a regulator of NRG1 type III function and peripheral nerve myelination

    Vimentin regulates peripheral nerve myelination.
    Triolo D, Dina G, Taveggia C, Vaccari I, Porrello E, Rivellini C, Domi T, La Marca R, Cerri F, Bolino A, Quattrini A, Previtali SC.

    05/5/2012
    Estradiol treatment leads to an effect on vimentin phosphorylation.

    Altered phosphorylation and distribution status of vimentin in rat seminiferous epithelium following 17β-estradiol treatment.
    Upadhyay R, D'Souza R, Sonawane S, Gaonkar R, Pathak S, Jhadav A, Balasinor NH.

    03/3/2012
    These data suggest that the inability of YY1 to access the hypermethylated promoter may be one of the mechanisms that mediate vimentin downregulation.

    CpG methylation prevents YY1-mediated transcriptional activation of the vimentin promoter.
    Sekimata M, Murakami-Sekimata A, Homma Y.

    01/7/2012
    Data show that vimentin intermediate filaments play a crucial role in mechanical behavior not only at large deformations but also in the nanomechanical response of individual cells.

    The nanomechanical properties of rat fibroblasts are modulated by interfering with the vimentin intermediate filament system.
    Plodinec M, Loparic M, Suetterlin R, Herrmann H, Aebi U, Schoenenberger CA.

    08/27/2011
    Data show that astrocyte structural proteins GFAP and vimentin are induced and by chronic leptin administration, suggesting astrocytes participating in leptin modulated synaptic inputs.

    Differential acute and chronic effects of leptin on hypothalamic astrocyte morphology and synaptic protein levels.
    García-Cáceres C, Fuente-Martín E, Burgos-Ramos E, Granado M, Frago LM, Barrios V, Horvath T, Argente J, Chowen JA., Free PMC Article

    07/23/2011
    GR-mediated reduction in vimentin may be involved in the formation of steroid-induced cataract

    Inhibition of glucocorticoid-induced alteration of vimentin by a glucocorticoid receptor antagonist RU486 in the organ-cultured rat lens.
    Xie GL, Yan H, Lu ZF., Free PMC Article

    05/28/2011
    Retinal injury induces an upregulation of a complement of four intermediate filament proteins, including synemin and nestin, in Muller cells.

    Expression profiles of nestin and synemin in reactive astrocytes and Müller cells following retinal injury: a comparison with glial fibrillar acidic protein and vimentin.
    Luna G, Lewis GP, Banna CD, Skalli O, Fisher SK., Free PMC Article

    02/26/2011
    Increases in post-traumatic vimentin mRNA in the cortex and in the hippocampus appear together with vimentin immunoreactivity in astrocytes starting at one day after severe trauma.

    Vimentin and GFAP responses in astrocytes after contusion trauma to the murine brain.
    Ekmark-Lewén S, Lewén A, Israelsson C, Li GL, Farooque M, Olsson Y, Ebendal T, Hillered L.

    12/4/2010
    Kidney cell proliferation, assessed by BrdU and PCNA labeling, was prominent in outer medulla and reach a maximum between 24 and 72 hours after reperfusion. This population was characterized by the coexpression of vimentin and nestin.

    Expression of nestin, vimentin, and NCAM by renal interstitial cells after ischemic tubular injury.
    Vansthertem D, Gossiaux A, Declèves AE, Caron N, Nonclercq D, Legrand A, Toubeau G., Free PMC Article

    10/23/2010
    Endothelial cell hypoxia causes redistribution of vimentin to a more insoluble and extensive filamentous network that could play a role in endothelial barrier stabilization.

    Regulation of vimentin intermediate filaments in endothelial cells by hypoxia.
    Liu T, Guevara OE, Warburton RR, Hill NS, Gaestel M, Kayyali US., Free PMC Article

    08/23/2010
    Vimentin mRNA and protein expression levels increased significantly throughout hepatotumorigenesis. Vimentin is an important node in underlying gene regulatory networks.

    IQGAP1 and vimentin are key regulator genes in naturally occurring hepatotumorigenesis induced by oxidative stress.
    Tsubota A, Matsumoto K, Mogushi K, Nariai K, Namiki Y, Hoshina S, Hano H, Tanaka H, Saito H, Tada N.

    04/19/2010
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