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    TRIM7 tripartite motif containing 7 [ Homo sapiens (human) ]

    Gene ID: 81786, updated on 3-Apr-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11.

    The E3 ligase TRIM7 suppresses the tumorigenesis of gastric cancer by targeting SLC7A11.
    Chen Q, Zhang T, Zeng R, Zhang K, Li B, Zhu Z, Ma X, Zhang Y, Li L, Zhu J, Zhang G., Free PMC Article

    03/22/2024
    TRIM7 inhibits encephalomyocarditis virus replication by activating interferon-beta signaling pathway.

    TRIM7 inhibits encephalomyocarditis virus replication by activating interferon-β signaling pathway.
    Li M, Yan J, Zhu H, Guo C, Jiang X, Gao Y, Liu X, Jiang P, Bai J.

    05/10/2023
    Study on the expression of TRIM7 in peripheral blood mononuclear cells of patients with sepsis and its early diagnostic value.

    Study on the expression of TRIM7 in peripheral blood mononuclear cells of patients with sepsis and its early diagnostic value.
    Lu M, Ma A, Liu J, Zhou W, Cao P, Chu T, Fan L., Free PMC Article

    11/26/2022
    A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.

    A C-terminal glutamine recognition mechanism revealed by E3 ligase TRIM7 structures.
    Liang X, Xiao J, Li X, Liu Y, Lu Y, Wen Y, Li Z, Che X, Ma Y, Zhang X, Zhang Y, Jian D, Wang P, Xuan C, Yu G, Li L, Zhang H.

    10/29/2022
    TRIM7 modulates NCOA4-mediated ferritinophagy and ferroptosis in glioblastoma cells.

    TRIM7 modulates NCOA4-mediated ferritinophagy and ferroptosis in glioblastoma cells.
    Li K, Chen B, Xu A, Shen J, Li K, Hao K, Hao R, Yang W, Jiang W, Zheng Y, Ge F, Wang Z., Free PMC Article

    10/8/2022
    GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.

    GNIP1 functions both as a scaffold protein and an E3 ubiquitin ligase to regulate autophagy in lung cancer.
    Zhou F, Liu Y, Ai W, Wang Y, Gan M, Jiang Q, Han T, Wang JB., Free PMC Article

    09/17/2022
    TRIM7 suppresses cell invasion and migration through inhibiting HIF-1alpha accumulation in clear cell renal cell carcinoma.

    TRIM7 suppresses cell invasion and migration through inhibiting HIF-1α accumulation in clear cell renal cell carcinoma.
    Yuan C, Liu J, Liu L, Jia H, Gao Q, Wang X, Zhao J.

    04/16/2022
    TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity.

    TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity.
    Fan W, Mar KB, Sari L, Gaszek IK, Cheng Q, Evers BM, Shelton JM, Wight-Carter M, Siegwart DJ, Lin MM, Schoggins JW., Free PMC Article

    01/8/2022
    Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS.

    Negative Regulation of RNF90 on RNA Virus-Triggered Antiviral Immune Responses Targeting MAVS.
    Yang B, Zhang G, Qin X, Huang Y, Ren X, Sun J, Ma S, Liu Y, Song D, Liu Y, Cui Y, Wang H, Wang J., Free PMC Article

    12/25/2021
    The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.

    The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein.
    Zhu L, Qin C, Li T, Ma X, Qiu Y, Lin Y, Ma D, Qin Z, Sun C, Shen X, Zhao Y, Han L., Free PMC Article

    09/11/2021
    Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1.

    Crystal structure and mutational analysis of the human TRIM7 B30.2 domain provide insights into the molecular basis of its binding to glycogenin-1.
    Muñoz Sosa CJ, Issoglio FM, Carrizo ME., Free PMC Article

    09/4/2021
    E3 ubiquitin ligase TRIM7 negatively regulates NF-kappa B signaling pathway by degrading p65 in lung cancer.

    E3 ubiquitin ligase TRIM7 negatively regulates NF-kappa B signaling pathway by degrading p65 in lung cancer.
    Jin J, Lu Z, Wang X, Liu Y, Han T, Wang Y, Wang T, Gan M, Xie C, Wang J, Yu B.

    07/31/2021
    N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1.

    N6-Methyladenosine modification of the TRIM7 positively regulates tumorigenesis and chemoresistance in osteosarcoma through ubiquitination of BRMS1.
    Zhou C, Zhang Z, Zhu X, Qian G, Zhou Y, Sun Y, Yu W, Wang J, Lu H, Lin F, Shen Z, Zheng S., Free PMC Article

    07/3/2021
    TRIM7 promotes proliferation and migration of vascular smooth muscle cells in atherosclerosis through activating c-Jun/AP-1.

    TRIM7 promotes proliferation and migration of vascular smooth muscle cells in atherosclerosis through activating c-Jun/AP-1.
    Ji R, Gu Y, Zhang J, Gao C, Gao W, Zang X, Zhao Y.

    10/24/2020
    TRIM7 expression was elevated in human hepatocellular carcinoma (HCC) tissues. TRIM7 knockdown inhibited HCC cell proliferation and induced a G1/S checkpoint. The DUSP6/p38 signaling mediated the functions of TRIM7 in human HCC cells.

    Tripartite motif-containing protein 7 regulates hepatocellular carcinoma cell proliferation via the DUSP6/p38 pathway.
    Hu X, Tang Z, Ma S, Yu Y, Chen X, Zang G.

    01/18/2020
    GNIP1 is an ubiquitin ligase with a markedly glycogenic effect in skeletal muscle.

    GNIP1 E3 ubiquitin ligase is a novel player in regulating glycogen metabolism in skeletal muscle.
    Montori-Grau M, Pedreira-Casahuga R, Boyer-Díaz Z, Lassot I, García-Martínez C, Orozco A, Cebrià J, Osorio-Conles O, Chacón MR, Vendrell J, Vázquez-Carrera M, Desagher S, Jiménez-Chillarón JC, Gómez-Foix AM.

    02/2/2019
    TRIM28 is a specific SUMO E3 ligase of interferon regulatory factor (IRF)7 and negatively regulates its activity and interferon (IFN)-based antiviral responses, in support of the expanding roles of TRIM proteins which regulate innate immunity.

    Tripartite motif-containing protein 28 is a small ubiquitin-related modifier E3 ligase and negative regulator of IFN regulatory factor 7.
    Liang Q, Deng H, Li X, Wu X, Tang Q, Chang TH, Peng H, Rauscher FJ 3rd, Ozato K, Zhu F., Free PMC Article

    01/28/2012
    GNIP, a novel protein that binds and activates glycogenin, the self-glucosylating initiator of glycogen biosynthesis

    GNIP, a novel protein that binds and activates glycogenin, the self-glucosylating initiator of glycogen biosynthesis.
    Skurat AV, Dietrich AD, Zhai L, Roach PJ.

    01/21/2010
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