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    VOPP1 VOPP1 WW domain binding protein [ Homo sapiens (human) ]

    Gene ID: 81552, updated on 19-Sep-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    The role of vesicular overexpressed in cancer pro-survival protein 1 in hepatocellular carcinoma proliferation.

    The role of vesicular overexpressed in cancer pro-survival protein 1 in hepatocellular carcinoma proliferation.
    Fang Z, Wu L, Dai H, Hu P, Wang B, Han Q, Xu Y, Lv S, Zhu Y, Gan M, Zhou W, Zhang W.

    02/6/2021
    VOPP1 expression was negatively regulated by microRNA-218.

    MicroRNA-218 alleviates sepsis inflammation by negatively regulating VOPP1 via JAK/STAT pathway.
    Li JM, Zhang H, Zuo YJ.

    11/16/2019
    The findings emphasize the importance of the sequestration of WWOX by VOPP1 in addition to WWOX loss in breast tumors and define VOPP1 as a novel oncogene promoting breast carcinogenesis by inhibiting the anti-tumoral effect of WWOX.

    VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX.
    Bonin F, Taouis K, Azorin P, Petitalot A, Tariq Z, Nola S, Bouteille N, Tury S, Vacher S, Bièche I, Rais KA, Pierron G, Fuhrmann L, Vincent-Salomon A, Formstecher E, Camonis J, Lidereau R, Lallemand F, Driouch K., Free PMC Article

    05/4/2019
    miR-218 inhibits human lung adenocarcinoma cell migration and invasion via the suppression of Ecop and Robo1 expression

    miR-218 suppresses epithelial-to-mesenchymal transition by targeting Robo1 and Ecop in lung adenocarcinoma cells.
    Li YJ, Zhang W, Xia H, Zhang BS, Chen P, Zhao YL, Li J.

    08/18/2018
    Candidate gene eQTL showed a trans-acting association between variants of G protein-coupled receptor kinase 5 gene, previously linked to altered BB response, and high expression of VOPP1.

    Gene signatures of postoperative atrial fibrillation in atrial tissue after coronary artery bypass grafting surgery in patients receiving β-blockers.
    Kertai MD, Qi W, Li YJ, Lombard FW, Liu Y, Smith MP, Stafford-Smith M, Newman MF, Milano CA, Mathew JP, Podgoreanu MV, Duke Perioperative Genetics and Safety Outcomes (PEGASUS) Investigative Team., Free PMC Article

    12/17/2016
    VOPP1 is overexpressed in gastric adenocarcinoma, which is involved in promoting cell proliferation and migration and thus might serve as a putative oncogene.

    Epidermal growth factor receptor-coamplified and overexpressed protein (VOPP1) is a putative oncogene in gastric cancer.
    Gao C, Pang M, Zhou Z, Long S, Dong D, Yang J, Cao M, Zhang C, Han S, Li L.

    07/30/2016
    Upregulation of ECOP is associated with glioma.

    MiR-218 sensitizes glioma cells to apoptosis and inhibits tumorigenicity by regulating ECOP-mediated suppression of NF-κB activity.
    Xia H, Yan Y, Hu M, Wang Y, Wang Y, Dai Y, Chen J, Di G, Chen X, Jiang X., Free PMC Article

    09/14/2013
    overexpression in cancer participates in the control of the intracellular redox state; its loss leads to oxidative cellular injury leading to cell death by the intrinsic apoptotic pathway

    Loss of VOPP1 overexpression in squamous carcinoma cells induces apoptosis through oxidative cellular injury.
    Baras AS, Solomon A, Davidson R, Moskaluk CA.

    09/24/2011
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (2) articles

    Association of genetic variants with hemorrhagic stroke in Japanese individuals.
    Yoshida T, Kato K, Yokoi K, Oguri M, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.

    Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.
    Oguri M, Kato K, Yokoi K, Yoshida T, Watanabe S, Metoki N, Yoshida H, Satoh K, Aoyagi Y, Nozawa Y, Yamada Y.

    12/2/2009
    Results identify ECOP as a protein relevant to the biology of SCC.

    Combined genomic and gene expression microarray profiling identifies ECOP as an upregulated gene in squamous cell carcinomas independent of DNA amplification.
    Baras A, Yu Y, Filtz M, Kim B, Moskaluk CA.

    01/21/2010
    ECOP was used as a molecular marker in patients with chronic wounds to guide surgical debridement.

    Molecular markers in patients with chronic wounds to guide surgical debridement.
    Brem H, Stojadinovic O, Diegelmann RF, Entero H, Lee B, Pastar I, Golinko M, Rosenberg H, Tomic-Canic M., Free PMC Article

    01/21/2010
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