| METTL3-mediated m[6]A methylation of SLC38A1 stimulates cervical cancer growth. | METTL3-mediated m(6)A methylation of SLC38A1 stimulates cervical cancer growth.
Liu HT, Zhao Y, Wang HC, Liu QL. | 08/7/2024 |
| OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1. | OTUD5 promotes the growth of hepatocellular carcinoma by deubiquitinating and stabilizing SLC38A1.
Yang Y, Jia S, Zhu N, Xiao X, Ma Y, Tu K, Guo Y, Xu Q., Free PMC Article | 04/26/2024 |
| CENPA promotes glutamine metabolism and tumor progression by up-regulating SLC38A1 in endometrial cancer. | CENPA promotes glutamine metabolism and tumor progression by up-regulating SLC38A1 in endometrial cancer.
Li S, Zhang Z, Li Z, Yang L, Liu J, Liu Y, Liu Y, Hou Y, Mei M, Huang Y. | 03/15/2024 |
| miRNA-432 and SLC38A1 as Predictors of Hepatocellular Carcinoma Complicated with Alcoholic Steatohepatitis. | miRNA-432 and SLC38A1 as Predictors of Hepatocellular Carcinoma Complicated with Alcoholic Steatohepatitis.
Cai C, Lin J, Li J, Wang XD, Xu LM, Chen DZ, Chen YP., Free PMC Article | 06/11/2022 |
| CircRUNX1 functions as an oncogene in colorectal cancer by regulating circRUNX1/miR-485-5p/SLC38A1 axis. | CircRUNX1 functions as an oncogene in colorectal cancer by regulating circRUNX1/miR-485-5p/SLC38A1 axis.
Yu J, Chen X, Li J, Wang F. | 12/25/2021 |
| Functional Consequences of Low Activity of Transport System A for Neutral Amino Acids in Human Bone Marrow Mesenchymal Stem Cells. | Functional Consequences of Low Activity of Transport System A for Neutral Amino Acids in Human Bone Marrow Mesenchymal Stem Cells.
Chiu M, Taurino G, Bianchi MG, Dander E, Fallati A, Giuliani N, D'Amico G, Bussolati O., Free PMC Article | 12/5/2020 |
| revealed SLC38A1 as a valuable prognostic and predictive marker for acute myeloid leukemia | High expression of SLC38A1 predicts poor prognosis in patients with de novo acute myeloid leukemia.
Li Y, Shao H, Da Z, Pan J, Fu B. | 06/6/2020 |
| High SNAT1 expression is associated with increased cell migration in breast neoplasms. | Actin depolymerization mediated loss of SNTA1 phosphorylation and Rac1 activity has implications on ROS production, cell migration and apoptosis.
Bhat SS, Parray AA, Mushtaq U, Fazili KM, Khanday FA. | 01/20/2018 |
| this study indicates that inhibition of miRNA-593-3p by insulin promotes glucose metabolism through the regulation of Slc38a1 and CLIP3 expression, and provides a new insight into the role and mechanism of insulin-induced glycolysis. | MicroRNA-593-3p regulates insulin-promoted glucose consumption by targeting Slc38a1 and CLIP3.
Yang X, Tao Z, Zhu Z, Liao H, Zhao Y, Fan H. | 10/28/2017 |
| Results found that SLC38A1 was up-regulated in colorectal cancer cells (CRC) and significantly associated with tumor invasion and advanced disease stage. Its overexpression enhanced growth and migration of HCT116 cells providing evidence that activation of SLC38A1 may play a critical role in CRC development and progression. | SLC38A1 promotes proliferation and migration of human colorectal cancer cells.
Zhou FF, Xie W, Chen SQ, Wang XK, Liu Q, Pan XK, Su F, Feng MH. | 04/8/2017 |
| In the absence of SLC1A5 there is a crucial role of SNAT1 in supplying glutamine for glutaminolysis with SNAT2 acting as a "backup" for glutamine transport. | Deletion of Amino Acid Transporter ASCT2 (SLC1A5) Reveals an Essential Role for Transporters SNAT1 (SLC38A1) and SNAT2 (SLC38A2) to Sustain Glutaminolysis in Cancer Cells.
Bröer A, Rahimi F, Bröer S., Free PMC Article | 11/19/2016 |
| The SLC38A1 protein was very low or undetectable in healthy gastric mucosa but strong staining of SLC38A1 protein was found in the cytoplasm in more than half of gastric cancer samples. SLC38A1 knockdown decreased tumor cell proliferation and migration. | Overexpression of SLC38A1 is associated with poorer prognosis in Chinese patients with gastric cancer.
Xie J, Li P, Gao HF, Qian JX, Yuan LY, Wang JJ., Free PMC Article | 12/20/2014 |
| SLC38A1 and SLC38A2 transcript levels are altered in placental malaria with intervillositis. | Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transport.
Boeuf P, Aitken EH, Chandrasiri U, Chua CL, McInerney B, McQuade L, Duffy M, Molyneux M, Brown G, Glazier J, Rogerson SJ., Free PMC Article | 09/6/2014 |
| The cross-talk between Akt signaling and SNAT1 might play a critical role in the development and progression of breast cancer | Activation of SNAT1/SLC38A1 in human breast cancer: correlation with p-Akt overexpression.
Wang K, Cao F, Fang W, Hu Y, Chen Y, Ding H, Yu G., Free PMC Article | 11/30/2013 |
| Increased expression of ATA1 is frequent in human hilar cholangiocarcinoma and significantly correlated with the progression of cholangiocarcinoma, suggesting the importance of ATA1 in cancer development and progression. | Overexpression of ATA1/SLC38A1 predicts future recurrence and death in Chinese patients with hilar cholangiocarcinoma.
Yu WL, Cong WM, Zhang Y, Chen Y, Wang F, Yu G. | 01/7/2012 |
| The results of this study provided that RAB2A and SLC38A1, were associated with the density of calbindin-positive neurons and the number of perineuronal oligodendrocytes in psychiatric disorders. | Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders.
Kim S, Webster MJ, Kim S, Webster MJ. | 07/23/2011 |
| results suggest that slc38a1 may play a role in the mechanisms underlying the determination of cellular viability in astrocytes through modulation of intracellular ROS generation | Exacerbated vulnerability to oxidative stress in astrocytic C6 glioma cells with stable overexpression of the glutamine transporter slc38a1.
Ogura M, Takarada T, Nakamichi N, Kawagoe H, Sako A, Nakazato R, Yoneda Y. | 06/18/2011 |
| SNAT1 is a key contributor to system A activity at term. | The contribution of SNAT1 to system A amino acid transporter activity in human placental trophoblast.
Desforges M, Greenwood SL, Glazier JD, Westwood M, Sibley CP., Free PMC Article | 08/23/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Observational study and genome-wide association study of gene-disease association. (HuGE Navigator) | Integrative genome-wide association analysis of cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders.
Kim S, Webster MJ, Kim S, Webster MJ. | 04/7/2010 |
| A possible association between low expression of SNAT1 and suicidal behavior is suggested. | SNAT1 and a family with high rates of suicidal behavior.
Ernst C, Dumoulin P, Cabot S, Erickson J, Turecki G. | 01/21/2010 |
| Report SNAT1 activity in fetal T lymphocytes in intrauterine growth restriction and with tumor necrosis factor-alpha treatment. | Amino acid transport systems beta and A in fetal T lymphocytes in intrauterine growth restriction and with tumor necrosis factor-alpha treatment.
Iruloh CG, D'Souza SW, Fergusson WD, Baker PN, Sibley CP, Glazier JD., Free PMC Article | 01/21/2010 |
| Theses data demonstrate the physiological importance of ATA1 in hepatocarcinogenesis. | Activation of a system A amino acid transporter, ATA1/SLC38A1, in human hepatocellular carcinoma and preneoplastic liver tissues.
Kondoh N, Imazeki N, Arai M, Hada A, Hatsuse K, Matsuo H, Matsubara O, Ohkura S, Yamamoto M. | 01/21/2010 |