| KIAA1199 deficiency enhances skeletal stem cell differentiation to osteoblasts and promotes bone regeneration. | KIAA1199 deficiency enhances skeletal stem cell differentiation to osteoblasts and promotes bone regeneration.
Chen L, Shi K, Ditzel N, Qiu W, Figeac F, Nielsen LHD, Tencerova M, Kowal JM, Ding M, Andreasen CM, Andersen TL, Kassem M., Free PMC Article | 04/12/2023 |
| CEMIP (KIAA1199) regulates inflammation, hyperplasia and fibrosis in osteoarthritis synovial membrane. | CEMIP (KIAA1199) regulates inflammation, hyperplasia and fibrosis in osteoarthritis synovial membrane.
Deroyer C, Poulet C, Paulissen G, Ciregia F, Malaise O, Plener Z, Cobraiville G, Daniel C, Gillet P, Malaise MG, de Seny D., Free PMC Article | 05/14/2022 |
| Sulfated hyaluronic acid inhibits the hyaluronidase CEMIP and regulates the HA metabolism, proliferation and differentiation of fibroblasts. | Sulfated hyaluronic acid inhibits the hyaluronidase CEMIP and regulates the HA metabolism, proliferation and differentiation of fibroblasts.
Schmaus A, Rothley M, Schreiber C, Möller S, Roßwag S, Franz S, Garvalov BK, Thiele W, Spataro S, Herskind C, Prunotto M, Anderegg U, Schnabelrauch M, Sleeman J. | 05/14/2022 |
| HYBID derived from tumor cells and tumor-associated macrophages contribute to the glioblastoma growth. | HYBID derived from tumor cells and tumor-associated macrophages contribute to the glioblastoma growth.
Tsuji S, Nakamura S, Yamada T, de Vega S, Okada Y, Inoue S, Shimazawa M, Hara H. | 01/22/2022 |
| CEMIP regulates the proliferation and migration of vascular smooth muscle cells in atherosclerosis through the WNT-beta-catenin signaling pathway. | CEMIP regulates the proliferation and migration of vascular smooth muscle cells in atherosclerosis through the WNT-beta-catenin signaling pathway.
Xue Q, Wang X, Deng X, Huang Y, Tian W. | 02/27/2021 |
| Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection. | Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection.
Dokoshi T, Zhang LJ, Li F, Nakatsuji T, Butcher A, Yoshida H, Shimoda M, Okada Y, Gallo RL., Free PMC Article | 01/9/2021 |
| KIAA1199 overexpression is an independent prognostic marker in non-small-cell lung cancer (NSCLC). KIAA1199 expression directly influences the expression of epithelial-mesenchymal transition (EMT) markers. KIAA1199 promotes invasion and migration in NSCLC via PI3K-Akt mediated EMT. | KIAA1199 promotes invasion and migration in non-small-cell lung cancer (NSCLC) via PI3K-Akt mediated EMT.
Tang Z, Ding Y, Shen Q, Zhang C, Li J, Nazar M, Wang Y, Zhou X, Huang J. | 05/9/2020 |
| CEMIP was overexpressed in human osteoarthritis (OA) cartilage and along chondrocytes dedifferentiation. CEMIP-regulated transdifferentiation of chondrocytes into "chondro-myo-fibroblasts" expressing alpha-SMA and type III collagen, two fibrosis markers. Moreover, these "chondro-myo-fibroblasts" were found in OA cartilage but not in healthy cartilage. | CEMIP (KIAA1199) induces a fibrosis-like process in osteoarthritic chondrocytes.
Deroyer C, Charlier E, Neuville S, Malaise O, Gillet P, Kurth W, Chariot A, Malaise M, de Seny D., Free PMC Article | 04/11/2020 |
| The KIAA1199, a protein that plays a role in a HA degradation pathway independent of the canonical hyaluronidases such as PH20, is specifically expressed in tissue lesions in which HA is degraded. | KIAA1199 expression and hyaluronan degradation colocalize in multiple sclerosis lesions.
Marella M, Jadin L, Keller GA, Sugarman BJ, Frost GI, Shepard HM., Free PMC Article | 03/2/2019 |
| KIAA1199 is overexpressed in pancreatic intraepithelial neoplasia. | Identification of KIAA1199 as a Biomarker for Pancreatic Intraepithelial Neoplasia.
Suh HN, Jun S, Oh AY, Srivastava M, Lee S, Taniguchi CM, Zhang S, Lee WS, Chen J, Park BJ, Park JI., Free PMC Article | 06/2/2018 |
| This work identifies KIAA1199 as a novel regulator of MEK/ERK-induced Schwann cell dedifferentiation and contributes to a better understanding of the molecular control of Schwann cell dedifferentiation. | KIAA1199: A novel regulator of MEK/ERK-induced Schwann cell dedifferentiation.
Boerboom A, Reusch C, Pieltain A, Chariot A, Franzen R. | 05/5/2018 |
| Results indicate that HYaluronan Binding Protein Involved in hyaluronan Depolymerization (Hybid) plays a key role in memory function in the brain. | Distribution and function of hyaluronan binding protein involved in hyaluronan depolymerization (HYBID, KIAA1199) in the mouse central nervous system.
Yoshino Y, Ishisaka M, Tsuruma K, Shimazawa M, Yoshida H, Inoue S, Shimoda M, Okada Y, Hara H. | 11/11/2017 |