| Evaluation of the association between clinical parameters and ADAM33 and ORMDL3 asthma gene single-nucleotide polymorphisms with the severity of COVID-19. | Evaluation of the association between clinical parameters and ADAM33 and ORMDL3 asthma gene single-nucleotide polymorphisms with the severity of COVID-19.
Khoramipour M, Jalali A, Abbasi B, Hadi Abbasian M. | 09/27/2023 |
| The rs16969968 Tobacco Smoking-Related Single-Nucleotide Variant Is Associated with Clinical Markers in Patients with Severe COVID-19. | The rs16969968 Tobacco Smoking-Related Single-Nucleotide Variant Is Associated with Clinical Markers in Patients with Severe COVID-19.
Valencia-Pérez Rea D, Falfán-Valencia R, Fricke-Galindo I, Buendía-Roldán I, Chávez-Galán L, Nava-Quiroz KJ, Alanis-Ponce J, Pérez-Rubio G., Free PMC Article | 08/28/2023 |
| Role of ADAM33 short isoform as a tumor suppressor in the pathogenesis of thyroid cancer via oncogenic function disruption of full-length ADAM33. | Role of ADAM33 short isoform as a tumor suppressor in the pathogenesis of thyroid cancer via oncogenic function disruption of full-length ADAM33.
Lan J, Zhou Y, Liu Y, Xia Y, Wan Y, Cao J., Free PMC Article | 06/28/2023 |
| The strong correlation between ADAM33 expression and airway inflammation in chronic obstructive pulmonary disease and candidate for biomarker and treatment of COPD. | The strong correlation between ADAM33 expression and airway inflammation in chronic obstructive pulmonary disease and candidate for biomarker and treatment of COPD.
Fachri M, Hatta M, Massi MN, Santoso A, Wikanningtyas TA, Dwiyanti R, Junita AR, Primaguna MR, Sabir M., Free PMC Article | 01/29/2022 |
| Signatures for chronic obstructive pulmonary disease (COPD) and asthma: a comparative genetic analysis. | Signatures for chronic obstructive pulmonary disease (COPD) and asthma: a comparative genetic analysis.
Sahu A, Swaroop S, Kant S, Banerjee M. | 01/22/2022 |
| Silencing a disintegrin and metalloproteinase33 attenuates the proliferation of vascular smooth muscle cells via PI3K/AKT pathway: Implications in the pathogenesis of airway vascular remodeling. | Silencing a disintegrin and metalloproteinase‑33 attenuates the proliferation of vascular smooth muscle cells via PI3K/AKT pathway: Implications in the pathogenesis of airway vascular remodeling.
Yan F, Hao Y, Gong X, Sun H, Ding J, Wang J., Free PMC Article | 10/16/2021 |
| ADAM33 rs2280090 and rs2280091 may be associated with asthma in a pilot case-control study | Haplotype analysis of ADAM33 polymorphisms in asthma: A pilot study.
Vishweswaraiah S, Ramachandra NB, Jayaraj BS, Holla AD, Chakraborty S, Agrawal A, Mahesh PA., Free PMC Article | 05/30/2020 |
| The rs2280089, rs2280090, and rs2280091 SNPs of ADAM33 appeared to be non-significant for asthma susceptibility in Northern and Central Punjabi population. | Evaluation of ADAM33 gene's single nucleotide polymorphism variants against asthma and the unique pattern of inheritance in Northern and Central Punjab, Pakistan.
Ghani MU, Sabar MF, Bano I, Shahid M, Akram M, Khalid I, Maryam A, Khan MU., Free PMC Article | 02/8/2020 |
| In a case-control study ADAM33 rs678881 polymorphism significantly increased the risk of childhood asthma in Chinese Han population, but not rs2280089 or rs2853209. | Genetic association of ADAM33 polymorphisms with childhood asthma in Chinese Han population: A case-control study.
Ning X, Zhang Y, Wu H, Bai L, Gong C, Wang Z., Free PMC Article | 10/26/2019 |
| ADAM33 F+1 mutant gene A may increase the risk of chronic obstructive pulmonary disease among the Asian population, while it may not associate with the European population | Association between F+1 polymorphism in a disintegrin and metalloprotease 33 (ADAM33) gene and chronic obstructive pulmonary disease susceptibility: An evidence-based meta-analysis.
Feng HH, Mao L, Pan K, Zhang L, Rui DS. | 10/5/2019 |
| Studies show alleles and genotypes of T2, Q1 and F + 1 polymorphisms in ADAM33 gene associate with asthma susceptibility among Asian populations, while V4 polymorphism associates with asthma among Caucasian populations | Association between ADAM33 polymorphisms and asthma risk: a systematic review and meta-analysis.
Li HF, Yan LP, Wang K, Li XT, Liu HX, Tan W., Free PMC Article | 07/27/2019 |
| we failed to show association between any genotype and allele of T1 and V4 SNPs in ADAM33 gene with susceptibility to asthma. | Investigating the Association of ADAM33 Single Nucleotide Polymorphisms (SNPs) with Susceptibility to Allergic Asthma in Azerbaijan Population of Iran: A Case-control Study.
Zeinaly I, Sadeghi-Shabestrai M, Babaloo Z, Razavi A, Sajay-Asbaghi M, Sadigh-Eteghad S, Kazemi T. | 07/13/2019 |
| IFN-gamma may participate in airway remodeling in asthma by downregulating the expression of the ADAM33 gene. | Effects of IFN-γ on cell growth and the expression of ADAM33 gene in human embryonic lung Mrc-5 fibroblasts in vitro.
Li W, Liang R, Huang H, Wu B, Zhong Y. | 01/12/2019 |
| This study suggests that metabolites of phthalate such as MEHHP, MECPP, MEOHP and Sigma4MEHP may increase the intron 1 methylation level to elevate ADAM33 gene expression and have a protective effect on reducing the risk of breast cancer. | Breast cancer is associated with methylation and expression of the a disintegrin and metalloproteinase domain 33 (ADAM33) gene affected by endocrine‑disrupting chemicals.
Yang PJ, Hou MF, Tsai EM, Liang SS, Chiu CC, Ou-Yang F, Kan JY, Peng CY, Wang TN. | 12/29/2018 |
| There was no significant difference in ADAM33 genotype and allele distributions between psoriasis and control groups (p > 0.05). CONCLUSIONS: ADAM33 V4 C/G rs2787094 polymorphism was not associated with psoriasis risk in the Turkish population. | ADAM 33 gene V4 C/G rs2787094 polymorphism in psoriasis.
Akcilar R, Namdar ND, Kocak FE, Bayat Z, Burhan H. | 11/24/2018 |
| A lower level of ADAM33 was also correlated with shorter overall survival and metastasis-free survival and was considered an independent prognostic factor suggesting that ADAM33 is a novel molecular biomarker of Triple-negative breast cancer and basal-like phenotype that might be useful as a prognostic factor. | Down regulation of ADAM33 as a Predictive Biomarker of Aggressive Breast Cancer.
Manica GC, Ribeiro CF, Oliveira MA, Pereira IT, Chequin A, Ramos EA, Klassen LM, Sebastião AP, Alvarenga LM, Zanata SM, Noronha L, Rabinovich I, Costa FF, Souza EM, Klassen G., Free PMC Article | 11/10/2018 |
| IL4RA and ADAM33 variants may be risk markers of asthma exacerbations in type-2 inflammatory endotype. Precise endotyping may facilitate the identification of genetic risk markers of asthma exacerbations. | IL4Rα and ADAM33 as genetic markers in asthma exacerbations and type-2 inflammatory endotype.
Sunadome H, Matsumoto H, Petrova G, Kanemitsu Y, Tohda Y, Horiguchi T, Kita H, Kuwabara K, Tomii K, Otsuka K, Fujimura M, Ohkura N, Tomita K, Yokoyama A, Ohnishi H, Nakano Y, Oguma T, Hozawa S, Nagasaki T, Ito I, Oguma T, Inoue H, Tajiri T, Iwata T, Izuhara Y, Ono J, Ohta S, Hirota T, Tamari M, Yokoyama T, Niimi A, Izuhara K, Mishima M. | 04/21/2018 |
| Collectively, our findings suggest that 1,25(OH)2D3 inhibits VEGF-induced ASM cell proliferation by suppressing VEGFR2 and ERK1/2 activation and downregulating ADAM33. Further studies of these mechanisms are needed to facilitate the development of treatments for smooth muscle hyperplasia-associated diseases of the airway such as asthma. | Effect of active vitamin D3 on VEGF-induced ADAM33 expression and proliferation in human airway smooth muscle cells: implications for asthma treatment.
Kim SH, Pei QM, Jiang P, Yang M, Qian XJ, Liu JB., Free PMC Article | 02/24/2018 |
| meta-analysis suggested that ADAM33 polymorphisms rs2280091, rs2280090, rs2787094, rs44707 and rs528557 were significantly associated with a high risk of childhood asthma | Association between ADAM metallopeptidase domain 33 gene polymorphism and risk of childhood asthma: a meta-analysis.
Sun FJ, Zou LY, Tong DM, Lu XY, Li J, Deng CB., Free PMC Article | 02/3/2018 |
| There was a significant difference in the frequency of ADAM33 V4 polymorphism in both, asthmatic and COPD patients groups. No significant differences were found for T1 polymorphism. However, there were significant differences when haplotypes and diplotypes of ADAM33 V4/T1 were compared in all three groups. It can be concluded that the polymorphism V4 of ADAM33 is associated with asthma or COPD in Venezuelan patients. | Single nucleotide polymorphisms V4 and T1 of the ADAM33 gene in Venezuelan patients with asthma or chronic obstructive pulmonary disease.
Martínez D, Lema D, Del Carmen Moreno D, Hipólito García A, Valentina Garmendia J, De Sanctis JB. | 08/5/2017 |
| Evidence from this meta-analysis demonstrates that ADAM33 T1 polymorphism might be associated with increased susceptibility to asthma among Asian children and that ADAM33 F + 1, T2, S2, or V4 polymorphism may be unrelated to susceptibility of childhood asthma. | T1 polymorphism in a disintegrin and metalloproteinase 33 (ADAM33) gene may contribute to the risk of childhood asthma in Asians.
Deng R, Zhao F, Zhong X. | 08/5/2017 |
| enhances ADAM-33 expression and airway smooth muscle cell proliferation | Upregulation of a disintegrin and metalloproteinase-33 by VEGF in human airway smooth muscle cells: Implications for asthma.
Pei QM, Jiang P, Yang M, Qian XJ, Liu JB, Zheng H, Zhao LH, Kim SH., Free PMC Article | 06/24/2017 |
| An association between ADAM33 gene polymorphism and impaired lung functions was detected in wood dust-exposed workers. | Association of ADAM33 gene polymorphism and arginase activity with susceptibility to ventilatory impairment in wood dust-exposed workers.
Saad-Hussein A, Thabet EH, Taha MM, Shahy EM, Mahdy-Abdallah H. | 02/18/2017 |
| This meta-analysis demonstrates that the ADAM33 gene polymorphisms confer susceptibility to allergic rhinitis | Association between ADAM33 S2 and V4 polymorphisms and susceptibility to allergic rhinitis: A meta-analysis.
Li Z, Yan F, Yang Z, Zhou J, Chen Y, Ding Z. | 12/17/2016 |
| findings suggest that genetic variants of ADAM33 gene may play important roles in asthma susceptibility in the Punjabi population of Pakistan | Genetic variants of ADAM33 are associated with asthma susceptibility in the Punjabi population of Pakistan.
Sabar MF, Ghani MU, Shahid M, Sumrin A, Ali A, Akram M, Tariq MA, Bano I. | 09/3/2016 |