| Expression of ZKSCAN3 protein suppresses proliferation, migration, and invasion of pancreatic cancer through autophagy. | Expression of ZKSCAN3 protein suppresses proliferation, migration, and invasion of pancreatic cancer through autophagy.
Nonoyama K, Matsuo Y, Sugita S, Eguchi Y, Denda Y, Murase H, Kato T, Imafuji H, Saito K, Morimoto M, Ogawa R, Takahashi H, Mitsui A, Kimura M, Takiguchi S., Free PMC Article | 07/8/2024 |
| Effect of Lacking ZKSCAN3 on Autophagy, Lysosomal Biogenesis and Senescence. | Effect of Lacking ZKSCAN3 on Autophagy, Lysosomal Biogenesis and Senescence.
Li XM, Wen JH, Feng ZS, Wu YS, Li DY, Liang S, Wu D, Wu HL, Li SM, Ye ZN, Yang C, Sun L, Tang JX, Liu HF., Free PMC Article | 05/19/2023 |
| Context-dependent pro- and anti-resection roles of ZKSCAN3 in the regulation of fork processing during replication stress. | Context-dependent pro- and anti-resection roles of ZKSCAN3 in the regulation of fork processing during replication stress.
Yang Z, Lemacon DS, Li S, Cheruiyot A, Kong L, Tan K, Cheng C, Turkay E, He D, You Z., Free PMC Article | 09/17/2022 |
| CHD1L augments autophagy-mediated migration of hepatocellular carcinoma through targeting ZKSCAN3. | CHD1L augments autophagy-mediated migration of hepatocellular carcinoma through targeting ZKSCAN3.
Zhang X, Bai Y, Huang L, Liu S, Mo Y, Cheng W, Wang G, Cao Z, Chen X, Cui H, Qi L, Ma L, Liu M, Guan XY, Ma NF., Free PMC Article | 02/5/2022 |
| Role of the Transcriptional Repressor Zinc Finger with KRAB and SCAN Domains 3 (ZKSCAN3) in Retinal Pigment Epithelial Cells. | Role of the Transcriptional Repressor Zinc Finger with KRAB and SCAN Domains 3 (ZKSCAN3) in Retinal Pigment Epithelial Cells.
Pan HY, Valapala M., Free PMC Article | 12/18/2021 |
| Human ZKSCAN3 and Drosophila M1BP are functionally homologous transcription factors in autophagy regulation. | Human ZKSCAN3 and Drosophila M1BP are functionally homologous transcription factors in autophagy regulation.
Barthez M, Poplineau M, Elrefaey M, Caruso N, Graba Y, Saurin AJ., Free PMC Article | 12/12/2020 |
| ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin. | ZKSCAN3 counteracts cellular senescence by stabilizing heterochromatin.
Hu H, Ji Q, Song M, Ren J, Liu Z, Wang Z, Liu X, Yan K, Hu J, Jing Y, Wang S, Zhang W, Liu GH, Qu J., Free PMC Article | 09/12/2020 |
| overexpression of ZKSCAN3 was frequently observed in gastric cancer cells and was significantly correlatedwith poorer clinical prognosis of patients with gastric cancer. | Prognostic Significance of ZKSCAN3 (ZNF306) Expression in Gastric Carcinoma.
Takano Y, Shida A, Fujisaki M, Mitsumori N, Yanaga K. | 01/18/2020 |
| ZKSCAN3 plays a significant role in the progression of breast cancer | ZKSCAN3 promotes breast cancer cell proliferation, migration and invasion.
Chi Y, Xu H, Wang F, Chen X, Shan Z, Sun Y, Fan Q. | 01/19/2019 |
| These results suggest that ZKSCAN3 plays an important role in bladder cancer outgrowth | ZKSCAN3 promotes bladder cancer cell proliferation, migration, and invasion.
Kawahara T, Inoue S, Ide H, Kashiwagi E, Ohtake S, Mizushima T, Li P, Li Y, Zheng Y, Uemura H, Netto GJ, Ishiguro H, Miyamoto H., Free PMC Article | 02/3/2018 |
| ZKSCAN3 appears to promote colorectal tumor progression and invasion. ZKSCAN3 may facilitate hepatic metastasis of CRC associated with CEA particularly in cases with CEA-producing tumor | ZKSCAN3 Facilitates Liver Metastasis of Colorectal Cancer Associated with CEA-expressing Tumor.
Kim CW, Roh SA, Tak KH, Koh BM, Ha YJ, Cho DH, Kim SY, Kim YS, Kim JC. | 02/4/2017 |
| Suggest ZKSCAN3 as an autophagy master switch regulating the expression of a transcriptional network of genes integral to autophagy and lysosome biogenesis/function. | ZKSCAN3 is a master transcriptional repressor of autophagy.
Chauhan S, Goodwin JG, Chauhan S, Manyam G, Wang J, Kamat AM, Boyd DD., Free PMC Article | 06/15/2013 |
| ZKSCAN3 induction represents a mechanism by which myeloma cells can induce cyclin D2 dysregulation and contribute to disease pathogenesis. | Evidence of a role for the novel zinc-finger transcription factor ZKSCAN3 in modulating Cyclin D2 expression in multiple myeloma.
Yang L, Wang H, Kornblau SM, Graber DA, Zhang N, Matthews JA, Wang M, Weber DM, Thomas SK, Shah JJ, Zhang L, Lu G, Zhao M, Muddasani R, Yoo SY, Baggerly KA, Orlowski RZ., Free PMC Article | 05/21/2011 |
| ZKSCAN3 regulates the expression of several genes favoring tumor progression including integrin beta 4 and VEGF | Unbiased screening for transcriptional targets of ZKSCAN3 identifies integrin beta 4 and vascular endothelial growth factor as downstream targets.
Yang L, Zhang L, Wu Q, Boyd DD., Free PMC Article | 01/21/2010 |
| ZKSCAN3 adds to an expanding set of encoded products contributing to the progression of colorectal cancer | The previously undescribed ZKSCAN3 (ZNF306) is a novel "driver" of colorectal cancer progression.
Yang L, Hamilton SR, Sood A, Kuwai T, Ellis L, Sanguino A, Lopez-Berestein G, Boyd DD. | 01/21/2010 |