DDX17 induces epithelial-mesenchymal transition and metastasis through the miR-149-3p/CYBRD1 pathway in colorectal cancer. | DDX17 induces epithelial-mesenchymal transition and metastasis through the miR-149-3p/CYBRD1 pathway in colorectal cancer. Zhao G, Wang Q, Zhang Y, Gu R, Liu M, Li Q, Zhang J, Yuan H, Feng T, Ou D, Li S, Li S, Li K, Mo C, Lin P., Free PMC Article | 01/14/2023 |
miR-423-3p activates FAK signaling pathway to drive EMT process and tumor growth in lung adenocarcinoma through targeting CYBRD1. | miR-423-3p activates FAK signaling pathway to drive EMT process and tumor growth in lung adenocarcinoma through targeting CYBRD1. Ma J, Huang W, Zhu C, Sun X, Zhang Q, Zhang L, Qi Q, Bai X, Feng Y, Wang C., Free PMC Article | 03/12/2022 |
Studied the effect of iron supplements containing Lactobacillus plantarum on ferric iron metabolism and upregulation of duodenal cytochrome b ferric-chelate reductase 3 (DCTYB) in Caco-2 and HT-29 MTX cell lines. | Iron Supplements Containing Lactobacillus plantarum 299v Increase Ferric Iron and Up-regulate the Ferric Reductase DCYTB in Human Caco-2/HT29 MTX Co-Cultures. Sandberg AS, Önning G, Engström N, Scheers N., Free PMC Article | 02/23/2019 |
Single nucleotide polymorphism in CYBRD1 gene is associated with hemochromatosis. | Duodenal cytochrome b (Cybrd1) ferric reductase functional studies in cells. Schlottmann F, Vera-Aviles M, Latunde-Dada GO. | 03/17/2018 |
CYBRD1 has an involvement in iron homeostasis in chronic hepatitis C. | Analysis of polymorphism and hepatic expression of duodenal cytochrome b in chronic hepatitis C. Rudnicka A, Woziwodzka A, Wróblewska A, Rybicka M, Bielawski KP, Sikorska K, Bernat A. | 09/23/2017 |
DCYTB is an important predictor of outcome and is associated with response to therapy in breast cancer patients. | DCYTB is a predictor of outcome in breast cancer that functions via iron-independent mechanisms. Lemler DJ, Lynch ML, Tesfay L, Deng Z, Paul BT, Wang X, Hegde P, Manz DH, Torti SV, Torti FM., Free PMC Article | 08/12/2017 |
Polymorphisms in CYBRD1 modulates iron phenotype in HFE p.C282Y homozygous hemochromatosis. | CYBRD1 as a modifier gene that modulates iron phenotype in HFE p.C282Y homozygous patients. Pelucchi S, Mariani R, Calza S, Fracanzani AL, Modignani GL, Bertola F, Busti F, Trombini P, Fraquelli M, Forni GL, Girelli D, Fargion S, Specchia C, Piperno A., Free PMC Article | 12/14/2013 |
Letter: report mutations in CYBRD1 promoter in and possible role in iron hemostasis in patients with porphyria cutanea tarda. | Iron homeostasis in porphyria cutanea tarda: mutation analysis of promoter regions of CP, CYBRD1, HAMP and SLC40A1. Panton NA, Strickland NJ, Hift RJ, Warnich L, Zaahl MG. | 03/23/2013 |
Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | A novel association between a SNP in CYBRD1 and serum ferritin levels in a cohort study of HFE hereditary haemochromatosis. Constantine CC, Anderson GJ, Vulpe CD, McLaren CE, Bahlo M, Yeap HL, Gertig DM, Osborne NJ, Bertalli NA, Beckman KB, Chen V, Matak P, McKie AT, Delatycki MB, Olynyk JK, English DR, Southey MC, Giles GG, Hopper JL, Allen KJ, Gurrin LC., Free PMC Article | 09/16/2009 |
The results of this study confirm that Dcytb can act as a ferric reductase that stimulates iron uptake in Caco-2 cells. | Duodenal cytochrome B expression stimulates iron uptake by human intestinal epithelial cells. Latunde-Dada GO, Simpson RJ, McKie AT. | 01/21/2010 |
Functional characterization of Cybrd1 heme groups and iron/ascorbate metabolism. | Functional characterization of human duodenal cytochrome b (Cybrd1): Redox properties in relation to iron and ascorbate metabolism. Oakhill JS, Marritt SJ, Gareta EG, Cammack R, McKie AT. | 01/21/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (4) articlesExamination of genetic polymorphisms in newborns for signatures of sex-specific prenatal selection. Ucisik-Akkaya E, Davis CF, Do TN, Morrison BA, Stemmer SM, Amadio WJ, Dorak MT. Gene variants associated with ischemic stroke: the cardiovascular health study. Luke MM, O'Meara ES, Rowland CM, Shiffman D, Bare LA, Arellano AR, Longstreth WT Jr, Lumley T, Rice K, Tracy RP, Devlin JJ, Psaty BM. Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Shiffman D, O'Meara ES, Bare LA, Rowland CM, Louie JZ, Arellano AR, Lumley T, Rice K, Iakoubova O, Luke MM, Young BA, Malloy MJ, Kane JP, Ellis SG, Tracy RP, Devlin JJ, Psaty BM. Analysis of genes implicated in iron regulation in individuals presenting with primary iron overload. Zaahl MG, Merryweather-Clarke AT, Kotze MJ, van der Merwe S, Warnich L, Robson KJ, Zaahl MG, Merryweather-Clarke AT, Kotze MJ, van der Merwe S, Warnich L, Robson KJ. | 03/13/2008 |
The current study concerns the recombinant expression, purification, and initial spectroscopic characterization of a recombinant form of the human ferric reductase. | Recombinant expression and initial characterization of the putative human enteric ferric reductase Dcytb. Ludwiczek S, Rosell FI, Ludwiczek ML, Mauk AG. | 01/21/2010 |
Duodenal cytochrome b present in human erythrocytes may contribute to their ability to reduce extracellular monodehydroascorbate. | Human erythrocyte membranes contain a cytochrome b561 that may be involved in extracellular ascorbate recycling. Su D, May JM, Koury MJ, Asard H. | 01/21/2010 |
In Africans with iron overload not related to the HFE gene, the possible involvement of the SLC40A1 and CYBRD1 genes was demonstrated for the first time. | Analysis of genes implicated in iron regulation in individuals presenting with primary iron overload. Zaahl MG, Merryweather-Clarke AT, Kotze MJ, van der Merwe S, Warnich L, Robson KJ, Zaahl MG, Merryweather-Clarke AT, Kotze MJ, van der Merwe S, Warnich L, Robson KJ. | 01/21/2010 |