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    LPCAT1 lysophosphatidylcholine acyltransferase 1 [ Homo sapiens (human) ]

    Gene ID: 79888, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    LPCAT1-mediated membrane phospholipid remodelling promotes ferroptosis evasion and tumour growth.

    LPCAT1-mediated membrane phospholipid remodelling promotes ferroptosis evasion and tumour growth.
    Li Z, Hu Y, Zheng H, Li M, Liu Y, Feng R, Li X, Zhang S, Tang M, Yang M, Yu R, Xu Y, Liao X, Chen S, Qian W, Zhang Q, Tang D, Li B, Song L, Li J.

    08/13/2024
    LPCAT1 promotes melanoma cell proliferation via Akt signaling.

    LPCAT1 promotes melanoma cell proliferation via Akt signaling.
    Wang Y, Huang Y, Wang Y, Zhang W, Wang N, Bai R, Luo R, Tuo H, Zheng Y., Free PMC Article

    04/5/2024
    Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis.

    Nuclear respiratory factor 1 drives hepatocellular carcinoma progression by activating LPCAT1-ERK1/2-CREB axis.
    Liu R, Yin C, Zhao P, Guo B, Ke W, Zheng X, Xie D, Wang Y, Wang G, Jia Y, Gao Y, Hu W, Liu GL, Song Z., Free PMC Article

    10/28/2023
    LncRNA AC012360.1 facilitates growth and metastasis by regulating the miR-139-5p/LPCAT1 axis in hepatocellular carcinoma.

    LncRNA AC012360.1 facilitates growth and metastasis by regulating the miR-139-5p/LPCAT1 axis in hepatocellular carcinoma.
    Zhao Y, Liu Y, Shi X.

    08/9/2023
    Biomarkers of ulcerative colitis disease activity CXCL1, CYP2R1, LPCAT1, and NEU4 and their relationship to immune infiltrates.

    Biomarkers of ulcerative colitis disease activity CXCL1, CYP2R1, LPCAT1, and NEU4 and their relationship to immune infiltrates.
    Huo A, Wang F., Free PMC Article

    07/31/2023
    LPCAT1 enhances the invasion and migration in gastric cancer: Based on computational biology methods and in vitro experiments.

    LPCAT1 enhances the invasion and migration in gastric cancer: Based on computational biology methods and in vitro experiments.
    Chen ZX, Liang L, Huang HQ, Li JD, He RQ, Huang ZG, Song R, Chen G, Li JJ, Cai ZW, Huang JA., Free PMC Article

    07/7/2023
    The validation and clinical significance of LPCAT1 down-regulation in acute myeloid leukemia.

    The validation and clinical significance of LPCAT1 down-regulation in acute myeloid leukemia.
    Chen Q, Xu Z, Lin J, Deng Z, Qian J, Qian W.

    05/30/2023
    Knockdown of LPCAT1 Repressed Hepatocellular Carcinoma Growth and Invasion by Targeting S100A11.

    Knockdown of LPCAT1 Repressed Hepatocellular Carcinoma Growth and Invasion by Targeting S100A11.
    Sun Q, Fu C, Liu J, Li S, Zheng J.

    04/26/2023
    Lysophosphatidylcholine acyltransferase 1 protein is present in maternal blood in the third trimester and is upregulated by antenatal corticosteroids.

    Lysophosphatidylcholine acyltransferase 1 protein is present in maternal blood in the third trimester and is upregulated by antenatal corticosteroids.
    Kramer KJ, Purandare N, Aras S, Parsian F, Sadek S, Chao C, Welch RA, Recanati MA.

    03/16/2023
    [Prognostic Significance of LPCAT1 in Adult Acute Myeloid Leukemia Patients with FAB Subtype M2].

    [Prognostic Significance of LPCAT1 in Adult Acute Myeloid Leukemia Patients with FAB Subtype M2].
    Liu Y, Liu YJ, Yang L, Zhang Y, Zhang DF, Jiang ZX, Wang C, Liu YF, Wang SJ.

    02/27/2023
    sn-1 Specificity of Lysophosphatidylcholine Acyltransferase-1 Revealed by a Mass Spectrometry-Based Assay.

    sn-1 Specificity of Lysophosphatidylcholine Acyltransferase-1 Revealed by a Mass Spectrometry-Based Assay.
    Zhao X, Liang J, Chen Z, Jian R, Qian Y, Wang Y, Guo Z, Zhang W, Zhang Y, Yin H, Xia Y.

    02/4/2023
    LPCAT1 acts as an independent prognostic biomarker correlated with immune infiltration in hepatocellular carcinoma.

    LPCAT1 acts as an independent prognostic biomarker correlated with immune infiltration in hepatocellular carcinoma.
    Li L, Wang X, Ding Y, Hui N, Su B, Yang M., Free PMC Article

    11/5/2022
    LPCAT1 functions as an oncogene in cervical cancer through mediating JAK2/STAT3 signaling.

    LPCAT1 functions as an oncogene in cervical cancer through mediating JAK2/STAT3 signaling.
    Gao F, Chen J, Zhang T, Liu N.

    10/29/2022
    Circular RNA circZCCHC6 contributes to tumorigenesis by regulating LPCAT1 via miR-433-3p in non-small cell lung cancer.

    Circular RNA circZCCHC6 contributes to tumorigenesis by regulating LPCAT1 via miR-433-3p in non-small cell lung cancer.
    Guo Y, Xue W, Sun S, Chen X, Li H, Yan C.

    10/29/2022
    Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating the TGF/beta-Smad2/3 signaling pathway.

    Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating the TGF/β-Smad2/3 signaling pathway.
    Zhao T, Sun R, Ma X, Wei L, Hou Y, Song K, Jiang J., Free PMC Article

    07/30/2022
    ncRNA-Mediated High Expression of LPCAT1 Correlates with Poor Prognosis and Tumor Immune Infiltration of Liver Hepatocellular Carcinoma.

    ncRNA-Mediated High Expression of LPCAT1 Correlates with Poor Prognosis and Tumor Immune Infiltration of Liver Hepatocellular Carcinoma.
    Sun Q, Liu X, Peng Q, Hu L, Jiang X., Free PMC Article

    06/18/2022
    Lysophosphatidylcholine Acyltransferase 1 Deficiency Promotes Pulmonary Emphysema via Apoptosis of Alveolar Epithelial Cells.

    Lysophosphatidylcholine Acyltransferase 1 Deficiency Promotes Pulmonary Emphysema via Apoptosis of Alveolar Epithelial Cells.
    Tanosaki T, Mikami Y, Shindou H, Suzuki T, Hashidate-Yoshida T, Hosoki K, Kagawa S, Miyata J, Kabata H, Masaki K, Hamamoto R, Kage H, Miyashita N, Makita K, Matsuzaki H, Suzuki Y, Mitani A, Nagase T, Shimizu T, Fukunaga K.

    06/18/2022
    Differential lysophosphatidylcholine acyltransferase 1 (LPCAT1) expression confers aggressiveness and independently predicts recurrence in bladder urothelial carcinomas.

    Differential lysophosphatidylcholine acyltransferase 1 (LPCAT1) expression confers aggressiveness and independently predicts recurrence in bladder urothelial carcinomas.
    Abdelzaher Ahmed E, Abdel Bary Abdel-Latif A, Fahmy AM, Elzarrouk Mania I.

    05/14/2022
    Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.

    Polypeptide N-acetylgalactosaminyltransferase 18 retains in endoplasmic reticulum depending on its luminal regions interacting with ER resident UGGT1, PLOD3 and LPCAT1.
    Jia W, Zou X, Xu Z, Bai L, Shan A, Li Y, Shi J, Yang F, Ding C, Narimatsu H, Zhang Y.

    04/9/2022
    Lysophosphatidylcholine acyltransferase 1 promotes pathology and toxicity in two distinct cell-based alpha-synuclein models.

    Lysophosphatidylcholine acyltransferase 1 promotes pathology and toxicity in two distinct cell-based alpha-synuclein models.
    Nicholatos JW, Tran D, Liu Y, Hirst WD, Weihofen A.

    03/26/2022
    LPCAT1 Promotes Cutaneous Squamous Cell Carcinoma via EGFR-Mediated Protein Kinase B/p38MAPK Signaling Pathways.

    LPCAT1 Promotes Cutaneous Squamous Cell Carcinoma via EGFR-Mediated Protein Kinase B/p38MAPK Signaling Pathways.
    Huang Y, Wang Y, Wang Y, Wang N, Duan Q, Wang S, Liu M, Bilal MA, Zheng Y.

    02/5/2022
    LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.

    LPCAT1 reprogramming cholesterol metabolism promotes the progression of esophageal squamous cell carcinoma.
    Tao M, Luo J, Gu T, Yu X, Song Z, Jun Y, Gu H, Han K, Huang X, Yu W, Sun S, Zhang Z, Liu L, Chen X, Zhang L, Luo C, Wang Q., Free PMC Article

    01/29/2022
    Molecular mechanisms regulating lysophosphatidylcholine acyltransferase 1 (LPCAT1) in human pregnancy.

    Molecular mechanisms regulating lysophosphatidylcholine acyltransferase 1 (LPCAT1) in human pregnancy.
    Purandare N, Minchella P, Somayajulu M, Kramer KJ, Zhou J, Adekoya N, Welch RA, Grossman LI, Aras S, Recanati MA., Free PMC Article

    01/1/2022
    Methylome and transcriptome profiling revealed epigenetic silencing of LPCAT1 and PCYT1A associated with lipidome alterations in polycystic ovary syndrome.

    Methylome and transcriptome profiling revealed epigenetic silencing of LPCAT1 and PCYT1A associated with lipidome alterations in polycystic ovary syndrome.
    Mao Z, Li T, Zhao H, Wang X, Kang Y, Kang Y.

    11/13/2021
    LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth.

    LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth.
    Oliver GR, Marcano-Bonilla S, Quist J, Tolosa EJ, Iguchi E, Swanson AA, Hoppman NL, Schwab T, Sigafoos A, Prodduturi N, Voss JS, Knight SM, Zhang J, Fadra N, Urrutia R, Zimmerman M, Egan JB, Bilyeu AG, Jen J, Veras E, Al-Safi R, Block M, Kerr S, Fernandez-Zapico ME, Schoolmeester JK, Klee EW., Free PMC Article

    11/6/2021
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