| High Vasohibin-2 expression correlated with autophagy in proliferative diabetic retinopathy. | High Vasohibin-2 expression correlated with autophagy in proliferative diabetic retinopathy.
Ding Y, Su N, Luan J, Xu J, Qiu S, Sun Z. | 03/5/2024 |
| A preliminary study on the mechanism of VASH2 in childhood medulloblastoma. | A preliminary study on the mechanism of VASH2 in childhood medulloblastoma.
Liu W, Fu Y, Wang M, Zhao J, Chen J, Wang Y, Qin H., Free PMC Article | 10/13/2023 |
| Pathological Study on the Expression of Vasohibins in Peripheral Artery Disease. | Pathological Study on the Expression of Vasohibins in Peripheral Artery Disease.
Isoda R, Morita I, Ishida A, Mikami Y, Monobe Y, Sato Y, Moriya T. | 10/1/2022 |
| [Vasohibin-2 promotes proliferation and metastasis of cervical cancer cells by regulating epithelial-mesenchymal transition]. | [Vasohibin-2 promotes proliferation and metastasis of cervical cancer cells by regulating epithelial-mesenchymal transition].
Wang J, Yu C, Jiang X, Wu X, Jia Y, Zhang H, Li Z., Free PMC Article | 07/30/2022 |
| Vasohibin-1 and -2 in pulmonary lymphangioleiomyomatosis (LAM) cells associated with angiogenic and prognostic factors. | Vasohibin-1 and -2 in pulmonary lymphangioleiomyomatosis (LAM) cells associated with angiogenic and prognostic factors.
Inoue C, Miki Y, Saito-Koyama R, Kobayashi K, Seyama K, Okada Y, Sasano H. | 03/26/2022 |
| Prognostic significance of vasohibin-1 and vasohibin-2 immunohistochemical expression in gastric cancer. | Prognostic significance of vasohibin-1 and vasohibin-2 immunohistochemical expression in gastric cancer.
Hara H, Ozawa S, Ninomiya Y, Yamamoto M, Ogimi M, Nabeshima K, Nakamura K, Kajiwara H, Nakamura N, Sato Y. | 11/28/2020 |
| VASH2 Promotes Cell Proliferation and Resistance to Doxorubicin in Non-Small Cell Lung Cancer via AKT Signaling. | VASH2 Promotes Cell Proliferation and Resistance to Doxorubicin in Non-Small Cell Lung Cancer via AKT Signaling.
Tan X, Liao Z, Zou S, Ma L, Wang A., Free PMC Article | 09/19/2020 |
| This study examined the crystal structures of human vasohibin 1 and 2 in complex with small vasohibin-binding protein (SVBP) in the absence and presence of different inhibitors and a C-terminal alpha-tubulin peptide. | Structural basis of tubulin detyrosination by the vasohibin-SVBP enzyme complex.
Wang N, Bosc C, Ryul Choi S, Boulan B, Peris L, Olieric N, Bao H, Krichen F, Chen L, Andrieux A, Olieric V, Moutin MJ, Steinmetz MO, Huang H. | 02/29/2020 |
| Study demonstrates that VASH2 promotes malignant behaviors of pancreatic cancer cells by inducing EMT via activation of the Hedgehog signaling pathway. | Vasohibin 2 promotes malignant behaviors of pancreatic cancer cells by inducing epithelial-mesenchymal transition via Hedgehog signaling pathway.
Zhang Y, Xue X, Zhao X, Qin L, Shen Y, Dou H, Sun J, Wang T, Yang DQ., Free PMC Article | 11/9/2019 |
| VASH2 promotes tumor angiogenesis as a result of paracrine activity and evasion of tumor immunity as a result of altered gene expression in pancreatic ductal adenocarcinoma cells. | Vasohibin-2 plays an essential role in metastasis of pancreatic ductal adenocarcinoma.
Iida-Norita R, Kawamura M, Suzuki Y, Hamada S, Masamune A, Furukawa T, Sato Y., Free PMC Article | 07/20/2019 |
| VASH2 may promote drug resistance of breast cancer cells through regulating ABCG2 via the AKT signaling pathway. | Vasohibin2 promotes adriamycin resistance of breast cancer cells through regulating ABCG2 via AKT signaling pathway.
Ma D, Wu L, Li S, Sun Z, Wang K. | 06/23/2018 |
| These results suggest that VASH-2 could play an important role in the pathogenesis of renal diseases, and that VASH-2 is closely associated with hypertension and impaired glucose tolerance. | Immunohistochemistry of Vasohibin-2 in Human Kidney Disease : Implications in Impaired Glucose Tolerance and Reduced Renal Function.
Arata Y, Tanabe K, Hinamoto N, Yamasaki H, Sugiyama H, Maeshima Y, Kanomata N, Sato Y, Wada J. | 06/16/2018 |
| VASH1 and VASH2 but not SVBP alone, increased detyrosination of -tubulin, and purified vasohibins removed the C-terminal tyrosine of -tubulin. | Vasohibins encode tubulin detyrosinating activity.
Nieuwenhuis J, Adamopoulos A, Bleijerveld OB, Mazouzi A, Stickel E, Celie P, Altelaar M, Knipscheer P, Perrakis A, Blomen VA, Brummelkamp TR. | 01/20/2018 |
| These results suggest that VASH2 plays an important role in gastric tumor progression via the accumulation of cancer-associated fibroblasts | Requisite role of vasohibin-2 in spontaneous gastric cancer formation and accumulation of cancer-associated fibroblasts.
Suzuki Y, Kitahara S, Suematsu T, Oshima M, Sato Y., Free PMC Article | 12/16/2017 |
| The present study suggests a protective effect of miR-200b/c on high glucose induced human retinal microvascular endothelial cell line dysfunction by inhibiting VASH2. | Protective effect of miR-200b/c by inhibiting vasohibin-2 in human retinal microvascular endothelial cells.
Ding Y, Hu Z, Luan J, Lv X, Yuan D, Xie P, Yuan S, Liu Q. | 12/2/2017 |
| VASH2 expression is positively correlated with FGF2 expression and promotes angiogenesis in human luminal breast cancer by transcriptional activation of fibroblast growth factor 2 through non-paracrine mechanisms. | Vasohibin 2 promotes human luminal breast cancer angiogenesis in a non-paracrine manner via transcriptional activation of fibroblast growth factor 2.
Tu M, Lu C, Lv N, Wei J, Lu Z, Xi C, Chen J, Guo F, Jiang K, Li Q, Wu J, Song G, Wang S, Gao W, Miao Y. | 08/12/2017 |
| These data suggest that VASH2 reduces the chemosensitivity to gemcitabine in pancreatic cancer cells via JUN-dependent transactivation of RRM2. | Vasohibin 2 reduces chemosensitivity to gemcitabine in pancreatic cancer cells via Jun proto-oncogene dependent transactivation of ribonucleotide reductase regulatory subunit M2.
Tu M, Li H, Lv N, Xi C, Lu Z, Wei J, Chen J, Guo F, Jiang K, Song G, Gao W, Miao Y., Free PMC Article | 07/29/2017 |
| identified a novel UPS regulatory system in which essential domain architecture (VASH-PS) of VASHs, comprising regions VASH191-180 and VASH280-169 , regulate the cytosolic punctate structure formation in the absence of SVBP. | Domain architecture of vasohibins required for their chaperone-dependent unconventional extracellular release.
Kadonosono T, Yimchuen W, Tsubaki T, Shiozawa T, Suzuki Y, Kuchimaru T, Sato Y, Kizaka-Kondoh S., Free PMC Article | 07/22/2017 |
| The results indicate that VASH2 played a significant role in the epithelial-mesenchymal transition by modulating the TGF-beta signaling. | Vasohibin-2 is required for epithelial-mesenchymal transition of ovarian cancer cells by modulating transforming growth factor-β signaling.
Norita R, Suzuki Y, Furutani Y, Takahashi K, Yoshimatsu Y, Podyma-Inoue KA, Watabe T, Sato Y., Free PMC Article | 05/6/2017 |
| to the best of our knowledge, these results are the first clinical data indicating that nuclear VASH2, but not cytoplasmic VASH2, promotes cell proliferation by driving the cell cycle from the G0/G1 to S phase. | Nuclear vasohibin-2 promotes cell proliferation by inducing G0/G1 to S phase progression.
Ge Q, Zhou J, Tu M, Xue X, Li Z, Lu Z, Wei J, Song G, Chen J, Guo F, Jiang K, Miao Y, Gao W. | 05/14/2016 |
| MiR200-upregulated Vasohibin 2 promotes the malignant transformation of tumors by inducing epithelial-mesenchymal transition in hepatocellular carcinoma | MiR200-upregulated Vasohibin 2 promotes the malignant transformation of tumors by inducing epithelial-mesenchymal transition in hepatocellular carcinoma.
Xue X, Zhang Y, Zhi Q, Tu M, Xu Y, Sun J, Wei J, Lu Z, Miao Y, Gao W., Free PMC Article | 10/24/2015 |
| Suggest that overexpression of VASH2 in pancreatic ductal adenocarcinoma accelerated the pace of tumor development toward a more serious malignant phenotype and was associated with a poor clinical outcome. | Expression of vasohibin-2 in pancreatic ductal adenocarcinoma promotes tumor progression and is associated with a poor clinical outcome.
Kim JC, Kim KT, Park JT, Kim HJ, Sato Y, Kim HS. | 06/20/2015 |
| VASH1 and VASH2 showed distinctive localization and opposing function on the fetoplacental vascularization. | Role of the vasohibin family in the regulation of fetoplacental vascularization and syncytiotrophoblast formation.
Suenaga K, Kitahara S, Suzuki Y, Kobayashi M, Horie S, Sugawara J, Yaegashi N, Sato Y., Free PMC Article | 05/30/2015 |
| VASH2 overexpression downregulated wild-type p53. | Vasohibin 2 decreases the cisplatin sensitivity of hepatocarcinoma cell line by downregulating p53.
Li Z, Tu M, Han B, Gu Y, Xue X, Sun J, Ge Q, Miao Y, Qian Z, Gao W., Free PMC Article | 02/14/2015 |
| VASH2 expressed in serous ovarian carcinoma cells promoted tumor growth and peritoneal dissemination by promoting angiogenesis. | Vasohibin-2 expressed in human serous ovarian adenocarcinoma accelerates tumor growth by promoting angiogenesis.
Takahashi Y, Koyanagi T, Suzuki Y, Saga Y, Kanomata N, Moriya T, Suzuki M, Sato Y. | 09/27/2014 |