| Tissue factor pathway inhibitor 2: Current understanding, challenges, and future perspectives. | Tissue factor pathway inhibitor 2: Current understanding, challenges, and future perspectives.
Kobayashi H, Matsubara S, Yoshimoto C, Shigetomi H, Imanaka S. | 11/6/2023 |
| Integrative analyses of RNA-seq and ChIP-seq Reveal MITF as a Target Gene of TFPI-2 in MDA231 Cells. | Integrative analyses of RNA-seq and ChIP-seq Reveal MITF as a Target Gene of TFPI-2 in MDA231 Cells.
Wang G, Zhang G, Zhu N, Zhu C, Kang M, Zuo G, Niu Z, Ye W, Tian B, Cai R. | 09/25/2023 |
| The role of tissue factor pathway inhibitor 2 in the coagulation and fibrinolysis system. | The role of tissue factor pathway inhibitor 2 in the coagulation and fibrinolysis system.
Kobayashi H, Matsubara S, Imanaka S. | 07/19/2023 |
| HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation. | HSP90-CDC37-PP5 forms a structural platform for kinase dephosphorylation.
Oberoi J, Guiu XA, Outwin EA, Schellenberger P, Roumeliotis TI, Choudhary JS, Pearl LH., Free PMC Article | 12/17/2022 |
| Exosomal miR-195 in hUC-MSCs alleviates hypoxia-induced damage of trophoblast cells through tissue factor pathway inhibitor 2. | Exosomal miR-195 in hUC-MSCs alleviates hypoxia-induced damage of trophoblast cells through tissue factor pathway inhibitor 2.
Zhou C, Wan S, Zhao X, Gu S, Pei J, Wu Y, Han Z, Che R, Hua X. | 11/26/2022 |
| m(6)A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2. | m(6)A RNA demethylase FTO promotes the growth, migration and invasion of pancreatic cancer cells through inhibiting TFPI-2.
Wang W, He Y, Zhai LL, Chen LJ, Yao LC, Wu L, Tang ZG, Ning JZ., Free PMC Article | 11/5/2022 |
| MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2. | MBD3 promotes hepatocellular carcinoma progression and metastasis through negative regulation of tumour suppressor TFPI2.
Yan W, Han Q, Gong L, Zhan X, Li W, Guo Z, Zhao J, Li T, Bai Z, Wu J, Huang Y, Lv L, Zhao H, Cai H, Huang S, Diao X, Chen Y, Gong W, Xia Q, Man J, Chen L, Dai G, Zhou T., Free PMC Article | 08/27/2022 |
| Tissue Factor Pathway Inhibitor 2: A Novel Biomarker for Predicting Asymptomatic Venous Thromboembolism in Patients with Epithelial Ovarian Cancer. | Tissue Factor Pathway Inhibitor 2: A Novel Biomarker for Predicting Asymptomatic Venous Thromboembolism in Patients with Epithelial Ovarian Cancer.
Yamanaka S, Miyake R, Yamada Y, Kawaguchi R, Ootake N, Myoba S, Kobayashi H. | 06/25/2022 |
| MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium. | MEG8 regulates Tissue Factor Pathway Inhibitor 2 (TFPI2) expression in the endothelium.
Kremer V, Bink DI, Stanicek L, van Ingen E, Gimbel T, Hilderink S, Günther S, Nossent AY, Boon RA., Free PMC Article | 03/5/2022 |
| The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer. | The methylation of SDC2 and TFPI2 defined three methylator phenotypes of colorectal cancer.
Lei R, Zhao Y, Huang K, Wang Q, Wan K, Li T, Yang H, Lv X., Free PMC Article | 03/5/2022 |
| Mechanisms of Systolic Cardiac Dysfunction in PP2A, PP5 and PP2AxPP5 Double Transgenic Mice. | Mechanisms of Systolic Cardiac Dysfunction in PP2A, PP5 and PP2AxPP5 Double Transgenic Mice.
Dörner MF, Boknik P, Köpp F, Buchwalow IB, Neumann J, Gergs U., Free PMC Article | 10/30/2021 |
| Toward an understanding of tissue factor pathway inhibitor-2 as a novel serodiagnostic marker for clear cell carcinoma of the ovary. | Toward an understanding of tissue factor pathway inhibitor-2 as a novel serodiagnostic marker for clear cell carcinoma of the ovary.
Kobayashi H, Imanaka S. | 09/11/2021 |
| TFPI-2 inhibits the invasion and metastasis of bladder cancer cells. | TFPI-2 inhibits the invasion and metastasis of bladder cancer cells.
Liu J, Xie J, Huang Y, Xie J, Yan X. | 08/14/2021 |
| TFPI2 and NDRG4 gene promoter methylation analysis in peripheral blood mononuclear cells are novel epigenetic noninvasive biomarkers for colorectal cancer diagnosis. | TFPI2 and NDRG4 gene promoter methylation analysis in peripheral blood mononuclear cells are novel epigenetic noninvasive biomarkers for colorectal cancer diagnosis.
Bagheri H, Mosallaei M, Bagherpour B, Khosravi S, Salehi AR, Salehi R. | 08/7/2021 |
| Low abundance of TFPI-2 by both promoter methylation and miR-27a-3p regulation is linked with poor clinical outcome in gastric cancer. | Low abundance of TFPI-2 by both promoter methylation and miR-27a-3p regulation is linked with poor clinical outcome in gastric cancer.
Geng G, Liu X, Xu A, Lu Z, Chen K, He J, Qi D, Yuan X. | 07/10/2021 |
| Validation of tissue factor pathway inhibitor 2 as a specific biomarker for preoperative prediction of clear cell carcinoma of the ovary. | Validation of tissue factor pathway inhibitor 2 as a specific biomarker for preoperative prediction of clear cell carcinoma of the ovary.
Miyagi E, Arakawa N, Sakamaki K, Yokota NR, Yamanaka T, Yamada Y, Yamaguchi S, Nagao S, Hirashima Y, Kasamatsu Y, Kato H, Mogami T, Miyagi Y, Kobayashi H., Free PMC Article | 06/26/2021 |
| TFPI2 suppresses breast cancer progression through inhibiting TWIST-integrin alpha5 pathway. | TFPI2 suppresses breast cancer progression through inhibiting TWIST-integrin α5 pathway.
Zhao D, Qiao J, He H, Song J, Zhao S, Yu J., Free PMC Article | 06/26/2021 |
| Indirect regulation of TFPI-2 expression by miR-494 in breast cancer cells. | Indirect regulation of TFPI-2 expression by miR-494 in breast cancer cells.
Andresen MS, Stavik B, Sletten M, Tinholt M, Sandset PM, Iversen N, Skretting G., Free PMC Article | 11/21/2020 |
| Two ways of epigenetic silencing of TFPI2 in cervical cancer. | Two ways of epigenetic silencing of TFPI2 in cervical cancer.
Fullár A, Karászi K, Hollósi P, Lendvai G, Oláh L, Reszegi A, Papp Z, Sobel G, Dudás J, Kovalszky I., Free PMC Article | 09/5/2020 |
| Results found that TFPI2, SOX17, and GATA4 are frequently hypermethylated in oral squamous cell carcinoma (OSCC) cell lines and tumors. The aberrant hypermethylation of these genes was associated with transcriptional silencing in OSCC cells. More importantly, the methylation status of TFPI2, GATA4, and SOX17 was significantly associated with OSCC patients' overall survival through TCGA DNA methylation database. | Aberrantly hypermethylated tumor suppressor genes were identified in oral squamous cell carcinoma (OSCC).
Kim SY, Han YK, Song JM, Lee CH, Kang K, Yi JM, Park HR., Free PMC Article | 06/20/2020 |
| localized to the cytoplasm of syncytiotrophoblast | Increased placental expression of Placental Protein 5 (PP5) / Tissue Factor Pathway Inhibitor-2 (TFPI-2) in women with preeclampsia and HELLP syndrome: Relevance to impaired trophoblast invasion?
Karaszi K, Szabo S, Juhasz K, Kiraly P, Kocsis-Deak B, Hargitai B, Krenacs T, Hupuczi P, Erez O, Papp Z, Kovalszky I, Than NG. | 03/14/2020 |
| expression of TFPI-2 gene in PEGFP-N1-TFPI-2 can inhibit the growth of SHI-1 cells | [Inhibitory Effect of Eukaryotic Expression Vector Bearing TFPI-2 Gene on SHI-1 Cell Growth].
Li JJ, Liao P, Wen F, Luo ZY, Cao YX. | 12/28/2019 |
| further investigation revealed that lncRNA AC003092.1 regulates TFPI-2 expression through miR-195 in glioblastoma (GB). Taken together, these data suggest that lncRNA AC003092.1 could inhibit the function of miR-195 by acting as an endogenous CeRNA, leading to increased expression of TFPI-2; this promotes TMZ-induced apoptosis, thereby making GB cells more sensitive to TMZ. | Long noncoding RNA AC003092.1 promotes temozolomide chemosensitivity through miR-195/TFPI-2 signaling modulation in glioblastoma.
Xu N, Liu B, Lian C, Doycheva DM, Fu Z, Liu Y, Zhou J, He Z, Yang Z, Huang Q, Zeng H, Guo H., Free PMC Article | 12/14/2019 |
| results suggest that TFPI-2 suppresses cancer cell proliferation and invasion partly through the regulation of the ERK1/2 signaling and through interactions with myosin-9 and actinin-4. | TFPI-2 suppresses breast cancer cell proliferation and invasion through regulation of ERK signaling and interaction with actinin-4 and myosin-9.
Wang G, Huang W, Li W, Chen S, Chen W, Zhou Y, Peng P, Gu W., Free PMC Article | 10/26/2019 |
| TFPI-2 Protects Against Gram-Negative Bacterial Infection. | TFPI-2 Protects Against Gram-Negative Bacterial Infection.
Ali MN, Kasetty G, Elvén M, Alyafei S, Jovic S, Egesten A, Herwald H, Schmidtchen A, Papareddy P., Free PMC Article | 09/28/2019 |