| Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin. | Human endogenous retrovirus onco-exaptation counters cancer cell senescence through calbindin.
Attig J, Pape J, Doglio L, Kazachenka A, Ottina E, Young GR, Enfield KS, Aramburu IV, Ng KW, Faulkner N, Bolland W, Papayannopoulos V, Swanton C, Kassiotis G., Free PMC Article | 10/30/2023 |
| Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca(2+) Levels in Senescent Cells. | Expression of the Calcium-Binding Protein CALB1 Is Induced and Controls Intracellular Ca(2+) Levels in Senescent Cells.
Raynard C, Tessier N, Huna A, Warnier M, Flaman JM, Van Coppenolle F, Ducreux S, Martin N, Bernard D., Free PMC Article | 09/3/2022 |
| Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients. | Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients.
Castrogiovanni P, Sanfilippo C, Imbesi R, Maugeri G, Lo Furno D, Tibullo D, Castorina A, Musumeci G, Di Rosa M., Free PMC Article | 10/23/2021 |
| Protective effects of calbindinD28K on the UVB radiationinduced apoptosis of human lens epithelial cells. | Protective effects of calbindin‑D28K on the UVB radiation‑induced apoptosis of human lens epithelial cells.
Liu K, Zhao J, Yang L, Guan M, Yuan L, Geng Y., Free PMC Article | 01/23/2021 |
| Advanced glycation end-products (AGEs) induced the calbindin-D28k expression in human renal proximal tubule cells (HK2), but not in mesangial cells. AGEs induced the expression of fibrotic molecules and endoplasmic reticulum (ER) stress-related molecules in HK2 cells, which could be inhibited by a receptor for AGE neutralizing antibody. | Role of Calbindin-D28k in Diabetes-Associated Advanced Glycation End-Products-Induced Renal Proximal Tubule Cell Injury.
Huang KH, Guan SS, Lin WH, Wu CT, Sheu ML, Chiang CK, Liu SH., Free PMC Article | 01/4/2020 |
| Knockdown of CALB1 inhibited the proliferation and colony formation of ovarian cancer cells. CALB1 interacts with MDM2 protooncogene (MDM2) and promoted the interaction between p53 and MDM2. | CALB1 enhances the interaction between p53 and MDM2, and inhibits the senescence of ovarian cancer cells.
Cao LQ, Wang YN, Liang M, Pan MZ., Free PMC Article | 09/7/2019 |
| Results suggest that CALB1 is a direct target of miR-454-3p and downregulation of CALB1 by miR-454-3p suppressed NSCLC cell functions. | Downregulation of Calbindin 1 by miR-454-3p Suppresses Cell Proliferation in Nonsmall Cell Lung Cancer In Vitro.
Jin C, Lin T, Shan L. | 07/20/2019 |
| the Calreticulin deficiency-mediated increase in cell death was not prevented by calbindin-D28k or Parvalbumin. | Calretinin Functions in Malignant Mesothelioma Cells Cannot Be Replaced by the Closely Related Ca(2+)-Binding Proteins Calbindin-D28k and Parvalbumin.
Wörthmüller J, Oberson A, Salicio V, Blum W, Schwaller B., Free PMC Article | 03/30/2019 |
| SAXS data collected in both the presence and absence of calcium indicate that there are no large structural differences in the globular structure of calbindin-D28K between the calcium-loaded and unloaded proteins. | The X-ray structure of human calbindin-D28K: an improved model.
Noble JW, Almalki R, Roe SM, Wagner A, Duman R, Atack JR., Free PMC Article | 01/19/2019 |
| CSF calbindin concentration is a sensitive biomarker of NPC1 disease | Cerebrospinal Fluid Calbindin D Concentration as a Biomarker of Cerebellar Disease Progression in Niemann-Pick Type C1 Disease.
Bradbury A, Bagel J, Sampson M, Farhat N, Ding W, Swain G, Prociuk M, O'Donnell P, Drobatz K, Gurda B, Wassif C, Remaley A, Porter F, Vite C., Free PMC Article | 05/27/2017 |
| We identified a significant association between the A allele of rs1805874 and the risk of Parkinson's disease (OR 1.257, 95% CI 1.036-1.524, p = 0.020). Our findings suggest that the A allele of rs1805874 is associated with risk of Parkinson's disease among the Han Chinese. Our results, combined with previous studies, suggest that rs1805874 is associated with Parkinson's disease in East Asians, but not Caucasians. | SNP rs1805874 of the Calbindin1 Gene Is Associated with Parkinson's Disease in Han Chinese.
Yang X, Zhao Q, An R, Zhou H, Lin Z, Xu Y. | 04/8/2017 |
| Age-related loss of CB appears to coincide with tangle formation in the BFCN and is associated with the full range of tau pathology, including late appearing epitopes. | Loss of calbindin-D28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease.
Ahmadian SS, Rezvanian A, Peterson M, Weintraub S, Bigio EH, Mesulam MM, Geula C., Free PMC Article | 08/20/2016 |
| Increased number of calbindin neurons and fiber labeling both in focal cortical dysplasia (FCD) and non-FCD specimens compared with postmortem controls may be associated with ongoing seizure activity. | Calcium-binding proteins in focal cortical dysplasia.
Kuchukhidze G, Wieselthaler-Hölzl A, Drexel M, Unterberger I, Luef G, Ortler M, Becker AJ, Trinka E, Sperk G., Free PMC Article | 10/17/2015 |
| expressed by different neuron types, both inhibitory (GABAergic) and excitatory (glutamatergic), involved in both intrinsic and extrinsic circuits of the human cerebellar cortex | Calbindin-D28K immunoreactivity in the human cerebellar cortex.
Flace P, Lorusso L, Laiso G, Rizzi A, Cagiano R, Nico B, Ribatti D, Ambrosi G, Benagiano V. | 02/14/2015 |
| The calbindin-D 28k was decreased in the putamen, the dorsal tier of the substantia nigra along the lower border of the red nucleus, and in the cerebellar cortex in multiple system atrophy. | Loss of DARPP-32 and calbindin in multiple system atrophy.
Hayakawa H, Nagai M, Kawanami A, Nakata Y, Nihira T, Ogino M, Takada M, Saido T, Takano J, Saegusa M, Mikami T, Hamada J, Nishiyama K, Mochizuki H, Mizuno Y., Free PMC Article | 07/12/2014 |
| Significantly reduced hippocampal calbindin D28K levels are found in all patients with mitochondrial encephalomyopathy, lactic acidosis and stroke-like syndrome (MELAS). | Decreased hippocampal expression of calbindin D28K and cognitive impairment in MELAS.
Emmanuele V, Garcia-Cazorla A, Huang HB, Coku J, Dorado B, Cortes EP, Engelstad K, De Vivo DC, Dimauro S, Bonilla E, Tanji K., Free PMC Article | 02/16/2013 |
| Data show calbindin (CB)- and tyrosine hydroxylase (TH)-cells were distributed in the three striatal territories, and the density of calretinin (CR) and parvalbumin (PV) interneurons were more abundant in the associative and sensorimotor striatum. | Distribution of GABAergic interneurons and dopaminergic cells in the functional territories of the human striatum.
Bernácer J, Prensa L, Giménez-Amaya JM., Free PMC Article | 06/16/2012 |
| Dynamics of Ca2+ ions within the solvation shell of calbindin D9k. | The dynamics of Ca2+ ions within the solvation shell of calbindin D9k.
Project E, Nachliel E, Gutman M., Free PMC Article | 09/3/2011 |
| upregulated in endometriosis tissues | DNA microarray analysis in a mouse model for endometriosis and validation of candidate factors with human adenomyosis.
Kusakabe KT, Abe H, Kondo T, Kato K, Okada T, Otsuki Y. | 11/27/2010 |
| cultured syncytiotrophoblast cells express calbindin-D9k and calbindin-D28k genes, which are stimulated by calcitriol | Effects of calcitriol on calbindins gene expression and lipid peroxidation in human placenta.
Halhali A, Figueras AG, Díaz L, Avila E, Barrera D, Hernández G, Larrea F. | 09/27/2010 |
| Our study shows there is no association between rs1805874 and risk for Parkinson's disease (PD) in four Caucasian populations. This suggests the effect of calbindin on PD risk displays population specificity. | Calbindin-1 association and Parkinson's disease.
Soto-Ortolaza AI, Behrouz B, Wider C, Vilariño-Güell C, Heckman MG, Aasly JO, Mark Gibson J, Lynch T, Jasinska-Myga B, Krygowska-Wajs A, Opala G, Barcikowska M, Czyzewski K, Uitti RJ, Wszolek ZK, Farrer MJ, Ross OA, Soto-Ortolaza AI, Behrouz B, Wider C, Vilariño-Güell C, Heckman MG, Aasly JO, Mark Gibson J, Lynch T, Jasinska-Myga B, Krygowska-Wajs A, Opala G, Barcikowska M, Czyzewski K, Uitti RJ, Wszolek ZK, Farrer MJ, Ross OA. | 08/23/2010 |
| calbindin may play a role in development of Purkinje cells located in heterotopias and cerebellar dysgenesias | Calbindin positive Purkinje cells in the pathology of human cerebellum occurring at the time of its development.
Laure-Kamionowska M, Maślińska D. | 04/12/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Calbindin-1 association and Parkinson's disease.
Soto-Ortolaza AI, Behrouz B, Wider C, Vilariño-Güell C, Heckman MG, Aasly JO, Mark Gibson J, Lynch T, Jasinska-Myga B, Krygowska-Wajs A, Opala G, Barcikowska M, Czyzewski K, Uitti RJ, Wszolek ZK, Farrer MJ, Ross OA, Soto-Ortolaza AI, Behrouz B, Wider C, Vilariño-Güell C, Heckman MG, Aasly JO, Mark Gibson J, Lynch T, Jasinska-Myga B, Krygowska-Wajs A, Opala G, Barcikowska M, Czyzewski K, Uitti RJ, Wszolek ZK, Farrer MJ, Ross OA. | 09/16/2009 |
| aggregates of mutant ataxin-l may recruit calbindin-D28k via tissue transglutaminase 2 mediated covalent crosslinking | Role of tissue transglutaminase type 2 in calbindin-D28k interaction with ataxin-1.
Vig PJ, Wei J, Shao Q, Hebert MD, Subramony SH, Sutton LT., Free PMC Article | 01/21/2010 |
| No significant differences in cerebellar Purkinje cells in levels of CALB in autism or in the normal cerebellum. | Cerebellar Purkinje cells are reduced in a subpopulation of autistic brains: a stereological experiment using calbindin-D28k.
Whitney ER, Kemper TL, Bauman ML, Rosene DL, Blatt GJ. | 01/21/2010 |