| DEK regulates B-cell proliferative capacity and is associated with aggressive disease in low-grade B-cell lymphomas. | DEK regulates B-cell proliferative capacity and is associated with aggressive disease in low-grade B-cell lymphomas.
Hopper MA, Dropik AR, Walker JS, Novak JP, Laverty MS, Manske MK, Wu X, Wenzl K, Krull JE, Sarangi V, Maurer MJ, Yang ZZ, Del Busso MD, Habermann TM, Link BK, Rimsza LM, Witzig TE, Ansell SM, Cerhan JR, Jevremovic D, Novak AJ., Free PMC Article | 10/10/2024 |
| Imaging-based study demonstrates how the DEK nanoscale distribution differentially correlates with epigenetic marks in a breast cancer model. | Imaging-based study demonstrates how the DEK nanoscale distribution differentially correlates with epigenetic marks in a breast cancer model.
Pierzynska-Mach A, Cainero I, Oneto M, Ferrando-May E, Lanzanò L, Diaspro A., Free PMC Article | 08/9/2023 |
| The impact of the chromatin binding DEK protein in hematopoiesis and acute myeloid leukemia. | The impact of the chromatin binding DEK protein in hematopoiesis and acute myeloid leukemia.
Wilcher KE, Page ERH, Privette Vinnedge LM., Free PMC Article | 06/30/2023 |
| Role of DEK in carcinogenesis, diagnosis, prognosis, and therapeutic outcome of breast cancer: An evidence-based clinical review. | Role of DEK in carcinogenesis, diagnosis, prognosis, and therapeutic outcome of breast cancer: An evidence-based clinical review.
Habiburrahman M, Sutopo S, Wardoyo MP. | 02/11/2023 |
| Doxorubicin induces prolonged DNA damage signal in cells overexpressing DEK isoform-2. | Doxorubicin induces prolonged DNA damage signal in cells overexpressing DEK isoform-2.
Özçelik E, Kalaycı A, Çelik B, Avcı A, Akyol H, Kılıç İB, Güzel T, Çetin M, Öztürk MT, Çalışkaner ZO, Tombaz M, Yoleri D, Konu Ö, Kandilci A., Free PMC Article | 10/15/2022 |
| p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma. | p21-activated kinase 2 binds to transcription factor SOX2 and up-regulates DEK to promote the progression of lung squamous cell carcinoma.
Xie S, Wan X, Chen S, Hu Y, Liu X. | 10/8/2022 |
| In silico gene expression and pathway analysis of DEK in the human brain across the lifespan. | In silico gene expression and pathway analysis of DEK in the human brain across the lifespan.
Greene AN, Nguyen ET, Paranjpe A, Lane A, Privette Vinnedge LM, Solomon MB., Free PMC Article | 10/1/2022 |
| Long Non-Coding LEF1-AS1 Sponge miR-5100 Regulates Apoptosis and Autophagy in Gastric Cancer Cells via the miR-5100/DEK/AMPK-mTOR Axis. | Long Non-Coding LEF1-AS1 Sponge miR-5100 Regulates Apoptosis and Autophagy in Gastric Cancer Cells via the miR-5100/DEK/AMPK-mTOR Axis.
Zhang H, Wang J, Wang Y, Li J, Zhao L, Zhang T, Liao X., Free PMC Article | 05/21/2022 |
| DEK modulates both expression and alternative splicing of cancerrelated genes. | DEK modulates both expression and alternative splicing of cancer‑related genes.
Liu B, Sun Y, Zhang Y, Xing Y, Suo J., Free PMC Article | 05/7/2022 |
| DEK-AFF2 Carcinoma of the Sinonasal Region and Skull Base: Detailed Clinicopathologic Characterization of a Distinctive Entity. | DEK-AFF2 Carcinoma of the Sinonasal Region and Skull Base: Detailed Clinicopathologic Characterization of a Distinctive Entity.
Rooper LM, Agaimy A, Dickson BC, Dueber JC, Eberhart CG, Gagan J, Hartmann A, Khararjian A, London NR, MacMillan CM, Palsgrove DN, Nix JS, Sandison A, Stoehr R, Truong T, Weinreb I, Bishop JA. | 12/4/2021 |
| KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation. | KIF15 upregulation promotes leiomyosarcoma cell growth via promoting USP15-mediated DEK deubiquitylation.
Ge W, Chen Y, Guo Y, Zhao D, Mu L, Zhang K, Zhuo W. | 11/22/2021 |
| [Prognostic significance of DEK-NUP214 fusion gene in patients with acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation]. | [Prognostic significance of DEK-NUP214 fusion gene in patients with acute myeloid leukemia after allogeneic hematopoietic stem cell transplantation].
Gao MG, Fu Q, Qin YZ, Chang YJ, Wang Y, Yan CH, Xu LP, Zhang XH, Huang XJ, Zhao XS. | 10/2/2021 |
| Bacterial Growth Inhibition Screen (BGIS) identifies a loss-of-function mutant of the DEK oncogene, indicating DNA modulating activities of DEK in chromatin. | Bacterial Growth Inhibition Screen (BGIS) identifies a loss-of-function mutant of the DEK oncogene, indicating DNA modulating activities of DEK in chromatin.
Guo H, Prell M, Königs H, Xu N, Waldmann T, Hermans-Sachweh B, Ferrando-May E, Lüscher B, Kappes F. | 07/17/2021 |
| MicroRNA-138 promotes neuroblastoma SH-SY5Y cell apoptosis by directly targeting DEK in Alzheimer's disease cell model. | MicroRNA-138 promotes neuroblastoma SH-SY5Y cell apoptosis by directly targeting DEK in Alzheimer's disease cell model.
Miao J, Jing J, Shao Y, Sun H., Free PMC Article | 06/12/2021 |
| Role of the DEK oncogene in the development of squamous cell carcinoma. | Role of the DEK oncogene in the development of squamous cell carcinoma.
Ishida K, Nakashima T, Shibata T, Hara A, Tomita H., Free PMC Article | 11/21/2020 |
| [Construction of RNA interference (RNAi) lentiviral expression vector of DEK gene and its effect on the biological behavior of liver cancer cells]. | [Construction of RNA interference (RNAi) lentiviral expression vector of DEK gene and its effect on the biological behavior of liver cancer cells].
Li SH, Hou Y, Chen Z, Wu WR, Wu CX, Sun H. | 10/31/2020 |
| DEK promotes the proliferation and invasion of lung cancers and indicates poor prognosis in lung adenocarcinomas. | DEK promotes the proliferation and invasion of lung cancers and indicates poor prognosis in lung adenocarcinomas.
Yang MQ, Bai LL, Lei L, Zheng YW, Wang Z, Li ZH, Liu CC, Huang WJ, Xu HT. | 09/19/2020 |
| the DEK shRNA cells demonstrated decreased invasive potential than their non-knockdown counterparts control cells. | Optical Redox Imaging Detects the Effects of DEK Oncogene Knockdown on the Redox State of MDA-MB-231 Breast Cancer Cells.
Wen Y, Xu HN, Privette Vinnedge L, Feng M, Li LZ., Free PMC Article | 05/9/2020 |
| Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling. | Secreted nuclear protein DEK regulates hematopoiesis through CXCR2 signaling.
Capitano ML, Mor-Vaknin N, Saha AK, Cooper S, Legendre M, Guo H, Contreras-Galindo R, Kappes F, Sartor MA, Lee CT, Huang X, Markovitz DM, Broxmeyer HE., Free PMC Article | 04/18/2020 |
| Knockdown of DEK resulted in inhibition of Gastric Cancer cell migration via a mechanism involving modulation of matrix metalloproteinase MMP-2/MMP-9 level and vice versa. | DEK Is a Potential Biomarker Associated with Malignant Phenotype in Gastric Cancer Tissues and Plasma.
Lee KF, Tsai MM, Tsai CY, Huang CG, Ou YH, Hsieh CC, Hsieh HL, Wang CS, Lin KH., Free PMC Article | 04/18/2020 |
| Male schizophrenia subjects had more anterior cingulate cortex DEK protein expression compared to male controls. Female schizophrenia subjects had less DEK protein expression compared to female controls. Finally, while there were no differences in DEK protein expression between control males and control females, males with schizophrenia had higher DEK protein expression compared to females with schizophrenia. | Sex differences in DEK expression in the anterior cingulate cortex and its association with dementia severity in schizophrenia.
O'Donovan SM, Franco-Villanueva A, Ghisays V, Caldwell JL, Haroutunian V, Privette Vinnedge LM, McCullumsmith RE, Solomon MB., Free PMC Article | 11/2/2019 |
| DEK is overexpressed in HGSOCs, and decreasing DEK levels significantly reduces cell viability and tumor growth, resulting in apoptotic cell death. | The DEK Oncoprotein Functions in Ovarian Cancer Growth and Survival.
Hacker KE, Bolland DE, Tan L, Saha AK, Niknafs YS, Markovitz DM, McLean K., Free PMC Article | 02/16/2019 |
| These findings define DEK as an important and multifunctional mediator of homologous recombination. | DEK is required for homologous recombination repair of DNA breaks.
Smith EA, Gole B, Willis NA, Soria R, Starnes LM, Krumpelbeck EF, Jegga AG, Ali AM, Guo H, Meetei AR, Andreassen PR, Kappes F, Vinnedge LM, Daniel JA, Scully R, Wiesmüller L, Wells SI., Free PMC Article | 11/17/2018 |
| DEK is detected in spontaneously forming neutrophil extracellular traps (NETs) from juvenile idiopathic arthritis patient synovial neutrophils, and DEK-targeted aptamers reduce NETs formation. | DEK-targeting DNA aptamers as therapeutics for inflammatory arthritis.
Mor-Vaknin N, Saha A, Legendre M, Carmona-Rivera C, Amin MA, Rabquer BJ, Gonzales-Hernandez MJ, Jorns J, Mohan S, Yalavarthi S, Pai DA, Angevine K, Almburg SJ, Knight JS, Adams BS, Koch AE, Fox DA, Engelke DR, Kaplan MJ, Markovitz DM., Free PMC Article | 11/10/2018 |
| High DEK proto-oncogene protein (DEK) expression associated with complete response to neoadjuvant chemoradiotherapy. | The potential predictive value of DEK expression for neoadjuvant chemoradiotherapy response in locally advanced rectal cancer.
Martinez-Useros J, Moreno I, Fernandez-Aceñero MJ, Rodriguez-Remirez M, Borrero-Palacios A, Cebrian A, Gomez Del Pulgar T, Del Puerto-Nevado L, Li W, Puime-Otin A, Perez N, Soengas MS, Garcia-Foncillas J., Free PMC Article | 08/25/2018 |