| Identification of AHNAK expression associated with the pathogenesis of chronic obstructive pulmonary disease by bioinformatic analysis. | Identification of AHNAK expression associated with the pathogenesis of chronic obstructive pulmonary disease by bioinformatic analysis.
Zhang C, Liu Y. | 12/27/2023 |
| Diagnostic and prognostic value of STAP1 and AHNAK methylation in peripheral blood immune cells for HBV-related hepatopathy. | Diagnostic and prognostic value of STAP1 and AHNAK methylation in peripheral blood immune cells for HBV-related hepatopathy.
Sun L, Lu J, Li K, Zhang H, Zhao X, Li G, Li N., Free PMC Article | 02/4/2023 |
| AHNAK suppresses ovarian cancer progression through the Wnt/beta-catenin signaling pathway. | AHNAK suppresses ovarian cancer progression through the Wnt/β-catenin signaling pathway.
Cai Y, Hu Y, Yu F, Tong W, Wang S, Sheng S, Zhu J., Free PMC Article | 01/28/2023 |
| Downregulation of Circ_0088196 Contributes to the Development of Trophoblastic Cells through miR-133b Sponging Function to Affect the AHNAK Expression. | Downregulation of Circ_0088196 Contributes to the Development of Trophoblastic Cells through miR-133b Sponging Function to Affect the AHNAK Expression.
Shi Y, Zhang L, Wang L, Ding H. | 12/24/2022 |
| CircAHNAK upregulates EIF2B5 expression to inhibit the progression of ovarian cancer by modulating the JAK2/STAT3 signaling pathway. | CircAHNAK upregulates EIF2B5 expression to inhibit the progression of ovarian cancer by modulating the JAK2/STAT3 signaling pathway.
He SL, Zhao X, Yi SJ. | 12/3/2022 |
| Identification of distinct genomic features reveals frequent somatic AHNAK and PTEN mutations predominantly in primary malignant melanoma presenting in the ureter. | Identification of distinct genomic features reveals frequent somatic AHNAK and PTEN mutations predominantly in primary malignant melanoma presenting in the ureter.
Huang Y, Wei L, Huang Y, Wen S, Liu T, Duan X, Wang Y, Zhang H, Fan B, Hu B. | 08/13/2022 |
| Annexin A2 and Ahnak control cortical NuMA-dynein localization and mitotic spindle orientation. | Annexin A2 and Ahnak control cortical NuMA-dynein localization and mitotic spindle orientation.
Pascal A, Gallaud E, Giet R, Benaud C. | 05/14/2022 |
| Interaction between TMEFF1 and AHNAK proteins in ovarian cancer cells: Implications for clinical prognosis. | Interaction between TMEFF1 and AHNAK proteins in ovarian cancer cells: Implications for clinical prognosis.
Nie X, Zheng M, Gao L, Hu Y, Zhuang Y, Li X, Zhu L, Liu J, Lin B. | 05/14/2022 |
| Identification of pannexin 1-regulated genes, interactome, and pathways in rhabdomyosarcoma and its tumor inhibitory interaction with AHNAK. | Identification of pannexin 1-regulated genes, interactome, and pathways in rhabdomyosarcoma and its tumor inhibitory interaction with AHNAK.
Xiang X, Langlois S, St-Pierre ME, Blinder A, Charron P, Graber TE, Fowler SL, Baird SD, Bennett SAL, Alain T, Cowan KN., Free PMC Article | 10/16/2021 |
| Peptide Derived from AHNAK Inhibits Cell Migration and Proliferation in Hirschsprung's Disease by Targeting the ERK1/2 Pathway. | Peptide Derived from AHNAK Inhibits Cell Migration and Proliferation in Hirschsprung's Disease by Targeting the ERK1/2 Pathway.
Li Y, Lv X, Chen H, Zhi Z, Wei Z, Wang B, Zhou L, Li H, Tang W. | 07/31/2021 |
| AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation. | AHNAK controls 53BP1-mediated p53 response by restraining 53BP1 oligomerization and phase separation.
Ghodke I, Remisova M, Furst A, Kilic S, Reina-San-Martin B, Poetsch AR, Altmeyer M, Soutoglou E., Free PMC Article | 07/24/2021 |
| MiR-222-5p promotes the growth and migration of trophoblasts by targeting AHNAK. | MiR-222-5p promotes the growth and migration of trophoblasts by targeting AHNAK.
Dong X, Zhao J, Han J, Han XJ, Zhao CM, Zou AX, Qi HG. | 06/26/2021 |
| SORBS1 serves a metastatic role via suppression of AHNAK in colorectal cancer cell lines. | SORBS1 serves a metastatic role via suppression of AHNAK in colorectal cancer cell lines.
Cho WC, Jang JE, Kim KH, Yoo BC, Ku JL., Free PMC Article | 02/13/2021 |
| CircAHNAK1 inhibits proliferation and metastasis of triple-negative breast cancer by modulating miR-421 and RASA1. | CircAHNAK1 inhibits proliferation and metastasis of triple-negative breast cancer by modulating miR-421 and RASA1.
Xiao W, Zheng S, Zou Y, Yang A, Xie X, Tang H, Xie X., Free PMC Article | 10/24/2020 |
| High AHNAK expression is associated with metastasis in Castration-Resistant Prostate Cancer. | BRD4 Regulates Metastatic Potential of Castration-Resistant Prostate Cancer through AHNAK.
Shafran JS, Andrieu GP, Györffy B, Denis GV., Free PMC Article | 04/18/2020 |
| Results showed that AHNAK methylation level in PBMC decreases with the exacerbation of HBV related liver disease, suggesting a certain correlation between AHNAK methylation and the progression of liver disease providing a potential differential diagnostic method for HBV-related hepatopathies, and an early detective tool for liver cancer. | Distinctive pattern of AHNAK methylation level in peripheral blood mononuclear cells and the association with HBV-related liver diseases.
Sun L, Li K, Liu G, Xu Y, Zhang A, Lin D, Zhang H, Zhao X, Jin B, Li N, Zhang Y., Free PMC Article | 12/21/2019 |
| Data show that AHNAK is a direct substrate of UBE3C, which elevated levels controlled the basal turnover of AHNAK by ubiquitin-mediated proteolysis. Elevated AHNAK levels and lower UBE3C levels predict better patient survival and might represent a prognostic marker in non-small-cell lung cancer (NSCLC). AHNAK is required for p53 binding to the promoter regions of stemness- related genes, thereby controlling cell stemness. | Ubiquitin-protein ligase E3C maintains non-small-cell lung cancer stemness by targeting AHNAK-p53 complex.
Gu J, Mao W, Ren W, Xu F, Zhu Q, Lu C, Lin Z, Zhang Z, Chu Y, Liu R, Ge D. | 11/9/2019 |
| AHNAK interference restored the hepatocellular carcinoma (HCC) cell invasion and metastasis deprived by RNF38 downregulation. Clinically, elevated RNF38 and transforming growth factor beta receptor 1 (TGFBR1) expression was related to short overall survival (OS) and high cumulative recurrence rates in HCC patients. | Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma.
Peng R, Zhang PF, Yang X, Wei CY, Huang XY, Cai JB, Lu JC, Gao C, Sun HX, Gao Q, Bai DS, Shi GM, Ke AW, Fan J., Free PMC Article | 06/22/2019 |
| this study identified a new biomarker, AHNAK, applicable to discrimination between bladder urothelial carcinoma and benign urothelial lesion by liquid-based cytology. | Quantitative Proteomic Analysis Identifies AHNAK (Neuroblast Differentiation-associated Protein AHNAK) as a Novel Candidate Biomarker for Bladder Urothelial Carcinoma Diagnosis by Liquid-based Cytology.
Lee H, Kim K, Woo J, Park J, Kim H, Lee KE, Kim H, Kim Y, Moon KC, Kim JY, Park IA, Shim BB, Moon JH, Han D, Ryu HS., Free PMC Article | 05/11/2019 |
| These findings confirm that AHNAK functions in the chemotherapeutic response of breast cancer cells while also emphasizing the need for further investigation into potential implications for AHNAK in terms of predicting and modulating treatment response. | Doxorubicin resistance in breast cancer: A novel role for the human protein AHNAK.
Davis T, van Niekerk G, Peres J, Prince S, Loos B, Engelbrecht AM. | 12/22/2018 |
| our results suggest that AHNAK acts as a tumor suppressor that negatively regulates TNBC cell proliferation, TNBC xenograft growth and metastasis via different signaling pathways. | AHNAK suppresses tumour proliferation and invasion by targeting multiple pathways in triple-negative breast cancer.
Chen B, Wang J, Dai D, Zhou Q, Guo X, Tian Z, Huang X, Yang L, Tang H, Xie X., Free PMC Article | 03/10/2018 |
| AHNAK enables mammary carcinoma cells to produce and release extracellular vesicles that cause disruption of the stroma by surrounding fibroblasts | AHNAK enables mammary carcinoma cells to produce extracellular vesicles that increase neighboring fibroblast cell motility.
Silva TA, Smuczek B, Valadão IC, Dzik LM, Iglesia RP, Cruz MC, Zelanis A, de Siqueira AS, Serrano SM, Goldberg GS, Jaeger RG, Freitas VM., Free PMC Article | 02/24/2018 |
| Based on the findings, the authors designate the Chlamydia trachomatis gene product corresponding to ct694-ctl0063translocated membrane-associated effector A (TmeA). Overall, the data reveal a role of TmeA during chlamydial invasion that manifests independently of effects on AHNAK. | Fluorescence-Reported Allelic Exchange Mutagenesis Reveals a Role for Chlamydia trachomatis TmeA in Invasion That Is Independent of Host AHNAK.
McKuen MJ, Mueller KE, Bae YS, Fields KA., Free PMC Article | 12/16/2017 |
| Examination of Gene Expression Omnibus database data sets suggests that downregulation of AHNAK mRNA and mutation of the AHNAK gene are common in metastatic melanoma and correlates to a poor outcome. | AHNAK is downregulated in melanoma, predicts poor outcome, and may be required for the expression of functional cadherin-1.
Sheppard HM, Feisst V, Chen J, Print C, Dunbar PR., Free PMC Article | 01/14/2017 |
| inhibition of Ahnak can promote generation of induced pluripotent stem cells (iPSC) via up-regulation of endogenous c-Myc. | Regulation of c-Myc Expression by Ahnak Promotes Induced Pluripotent Stem Cell Generation.
Lim HJ, Kim J, Park CH, Lee SA, Lee MR, Kim KS, Kim J, Bae YS., Free PMC Article | 05/21/2016 |