| CSDE1 attenuates microRNA-mediated silencing of PMEPA1 in melanoma. | CSDE1 attenuates microRNA-mediated silencing of PMEPA1 in melanoma.
Kakumani PK, Guitart T, Houle F, Harvey LM, Goyer B, Germain L, Gebauer F, Simard MJ. | 07/26/2024 |
| CSDE1 promotes miR-451 biogenesis. | CSDE1 promotes miR-451 biogenesis.
Kakumani PK, Ko Y, Ramakrishna S, Christopher G, Dodgson M, Shrinet J, Harvey LM, Shin C, Simard MJ., Free PMC Article | 09/26/2023 |
| Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor. | Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor.
Smith GA, Padmanabhan A, Lau BH, Pampana A, Li L, Lee CY, Pelonero A, Nishino T, Sadagopan N, Xia VQ, Jain R, Natarajan P, Wu RS, Black BL, Srivastava D, Shokat KM, Chorba JS., Free PMC Article | 10/1/2022 |
| Reduced miR-371b-5p expression drives tumor progression via CSDE1/RAC1 regulation in triple-negative breast cancer. | Reduced miR-371b-5p expression drives tumor progression via CSDE1/RAC1 regulation in triple-negative breast cancer.
Kim Y, Ko JY, Lee SB, Oh S, Park JW, Kang HG, Kim DH, Chung D, Lim S, Kong H, Kim J, Yoo KH, Han W, Chun KH, Park JH., Free PMC Article | 07/9/2022 |
| Coordinated post-transcriptional control of oncogene-induced senescence by UNR/CSDE1. | Coordinated post-transcriptional control of oncogene-induced senescence by UNR/CSDE1.
Avolio R, Inglés-Ferrándiz M, Ciocia A, Coll O, Bonnin S, Guitart T, Ribó A, Gebauer F. | 02/19/2022 |
| The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1. | The CDT of Helicobacter hepaticus induces pro-survival autophagy and nucleoplasmic reticulum formation concentrating the RNA binding proteins UNR/CSDE1 and P62/SQSTM1.
He W, Azzi-Martin L, Velasco V, Lehours P, Dubus P, Djavaheri-Mergny M, Ménard A., Free PMC Article | 07/24/2021 |
| Cold Shock Domain Containing E1 (CSDE1) Protein is Overexpressed and Can be Targeted to Inhibit Invasiveness in Pancreatic Cancer Cells. | Cold Shock Domain Containing E1 (CSDE1) Protein is Overexpressed and Can be Targeted to Inhibit Invasiveness in Pancreatic Cancer Cells.
Liu H, Li X, Dun MD, Faulkner S, Jiang CC, Hondermarck H. | 05/29/2021 |
| Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy. | Oncolytic virotherapy induced CSDE1 neo-antigenesis restricts VSV replication but can be targeted by immunotherapy.
Kottke T, Tonne J, Evgin L, Driscoll CB, van Vloten J, Jennings VA, Huff AL, Zell B, Thompson JM, Wongthida P, Pulido J, Schuelke MR, Samson A, Selby P, Ilett E, McNiven M, Roberts LR, Borad MJ, Pandha H, Harrington K, Melcher A, Vile RG., Free PMC Article | 04/17/2021 |
| The role of CSDE1 in translational reprogramming and human diseases. | The role of CSDE1 in translational reprogramming and human diseases.
Guo AX, Cui JJ, Wang LY, Yin JY., Free PMC Article | 09/12/2020 |
| Our study defines a new autism-related syndrome and highlights the functional role of CSDE1 in synapse development and synaptic transmission. | Disruptive variants of CSDE1 associate with autism and interfere with neuronal development and synaptic transmission.
Guo H, Li Y, Shen L, Wang T, Jia X, Liu L, Xu T, Ou M, Hoekzema K, Wu H, Gillentine MA, Liu C, Ni H, Peng P, Zhao R, Zhang Y, Phornphutkul C, Stegmann APA, Prada CE, Hopkin RJ, Shieh JT, McWalter K, Monaghan KG, van Hasselt PM, van Gassen K, Bai T, Long M, Han L, Quan Y, Chen M, Zhang Y, Li K, Zhang Q, Tan J, Zhu T, Liu Y, Pang N, Peng J, Scott DA, Lalani SR, Azamian M, Mancini GMS, Adams DJ, Kvarnung M, Lindstrand A, Nordgren A, Pevsner J, Osei-Owusu IA, Romano C, Calabrese G, Galesi O, Gecz J, Haan E, Ranells J, Racobaldo M, Nordenskjold M, Madan-Khetarpal S, Sebastian J, Ball S, Zou X, Zhao J, Hu Z, Xia F, Liu P, Rosenfeld JA, de Vries BBA, Bernier RA, Xu ZD, Li H, Xie W, Hufnagel RB, Eichler EE, Xia K., Free PMC Article | 05/23/2020 |
| Csde1 is involved in feed-back control in protein homeostasis and that it dampens stochastic changes in mRNA expression | Csde1 binds transcripts involved in protein homeostasis and controls their expression in an erythroid cell line.
Moore KS, Yagci N, van Alphen F, Paolini NA, Horos R, Held NM, Houtkooper RH, van den Akker E, Meijer AB, 't Hoen PAC, von Lindern M., Free PMC Article | 08/24/2019 |
| CSDE1 binds directly to BC200 RNA.CSDE1 and BC200 expression levels are mutually dependent. | Comprehensive analysis of the BC200 ribonucleoprotein reveals a reciprocal regulatory function with CSDE1/UNR.
Booy EP, McRae EK, Ezzati P, Choi T, Gussakovsky D, McKenna SA., Free PMC Article | 07/13/2019 |
| Strap associates with Csde1 and affects expression of select Csde1-bound transcripts | Strap associates with Csde1 and affects expression of select Csde1-bound transcripts.
Moore KS, Yagci N, van Alphen F, Meijer AB, 't Hoen PAC, von Lindern M., Free PMC Article | 02/9/2019 |
| CSDE1 post-transcriptionally modulates core components of multiple regulatory nodes of human embryonic stem cell identity, neuroectoderm commitment and neurogenesis and acts as a negative regulator of neural differentiation and neurogenesis. | A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells.
Ju Lee H, Bartsch D, Xiao C, Guerrero S, Ahuja G, Schindler C, Moresco JJ, Yates JR 3rd, Gebauer F, Bazzi H, Dieterich C, Kurian L, Vilchez D., Free PMC Article | 09/15/2018 |
| UNR/CDSE1 expression is correlated with outcome in patients with resectable pancreatic ductal adenocarcinoma | UNR/CDSE1 expression as prognosis biomarker in resectable pancreatic ductal adenocarcinoma patients: A proof-of-concept.
Martinez-Useros J, Georgiev-Hristov T, Fernández-Aceñero MJ, Borrero-Palacios A, Indacochea A, Guerrero S, Li W, Cebrián A, Gómez Del Pulgar T, Puime-Otin A, Del Puerto-Nevado L, Rodríguez-Remírez M, Pérez N, Celdrán A, Gebauer F, Garcia-Foncillas J., Free PMC Article | 10/23/2017 |
| Results identify UNR as an oncogenic modulator of melanoma progression, unraveling the underlying molecular mechanisms. UNR seems to regulate translation elongation of Vimentin and RAC1 mRNAs. | UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis.
Wurth L, Papasaikas P, Olmeda D, Bley N, Calvo GT, Guerrero S, Cerezo-Wallis D, Martinez-Useros J, García-Fernández M, Hüttelmaier S, Soengas MS, Gebauer F. | 06/3/2017 |
| Studies indicate that Unr (upstream of N-ras) is post-translationally modified by phosphorylation and lysine acetylation. | Regulation of the expression and activity of Unr in mammalian cells.
Anderson EC, Catnaigh PÓ. | 09/17/2016 |
| Hepsin suppressed CDK11p58 internal ribosome entry site activity in prostate cancer cells by modulating UNR expression and eIF-2alpha phosphorylation. | Hepsin inhibits CDK11p58 IRES activity by suppressing unr expression and eIF-2α phosphorylation in prostate cancer.
Zhang C, Zhang M, Wu Q, Peng J, Ruan Y, Gu J. | 12/26/2015 |
| Study suggests TRIM33 and NRAS-CSDE1 as candidate genes for autism, and may provide a novel insight into the etiology of autism | Common genetic variants on 1p13.2 associate with risk of autism.
Xia K, Guo H, Hu Z, Xun G, Zuo L, Peng Y, Wang K, He Y, Xiong Z, Sun L, Pan Q, Long Z, Zou X, Li X, Li W, Xu X, Lu L, Liu Y, Hu Y, Tian D, Long L, Ou J, Liu Y, Li X, Zhang L, Pan Y, Chen J, Peng H, Liu Q, Luo X, Su W, Wu L, Liang D, Dai H, Yan X, Feng Y, Tang B, Li J, Miedzybrodzka Z, Xia J, Zhang Z, Luo X, Zhang X, St Clair D, Zhao J, Zhang F. | 07/25/2015 |
| Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator) | Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.
Casabonne D, Reina O, Benavente Y, Becker N, Maynadié M, Foretová L, Cocco P, González-Neira A, Nieters A, Boffetta P, Middeldorp JM, de Sanjose S., Free PMC Article | 12/5/2010 |
| Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) | Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article | 09/15/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium., Free PMC Article | 09/15/2010 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| The data suggest that Unr acts as an RNA chaperone on rhinovirus RNA 5' UTR to maintain a complex tertiary internal ribosome entry site structure required for translational competency. | Internal initiation of translation from the human rhinovirus-2 internal ribosome entry site requires the binding of Unr to two distinct sites on the 5' untranslated region.
Anderson EC, Hunt SL, Jackson RJ. | 01/21/2010 |
| UNR translation is regulated by an internal ribosome entry site that is downregulated by polypyrimidine tract binding protein. | UNR translation can be driven by an IRES element that is negatively regulated by polypyrimidine tract binding protein.
Cornelis S, Tinton SA, Schepens B, Bruynooghe Y, Beyaert R., Free PMC Article | 01/21/2010 |