CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1. | CXXC5 drove inflammation and ovarian cancer proliferation via transcriptional activation of ZNF143 and EGR1. Geng T, Sun Q, He J, Chen Y, Cheng W, Shen J, Liu B, Zhang M, Wang S, Asan K, Song M, Gao Q, Song Y, Liu R, Liu X, Ding Y, Jing A, Ye X, Ren H, Zeng K, Zhou Y, Zhang B, Ma S, Liu W, Liu S, Ji J. | 06/14/2024 |
LOC644656 promotes cisplatin resistance in cervical cancer by recruiting ZNF143 and activating the transcription of E6-AP. | LOC644656 promotes cisplatin resistance in cervical cancer by recruiting ZNF143 and activating the transcription of E6-AP. Li M, Chen J, Zhang H, Zhang Y, Wang J, Shen Z, Chen Y, Hou W, Chi C. | 03/15/2024 |
ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling. | ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling. Chen Y, Li J, Ma J, Bao Y., Free PMC Article | 07/12/2023 |
ATF1 promotes the malignancy of lung adenocarcinoma cells by transcriptionally regulating ZNF143 expression. | ATF1 promotes the malignancy of lung adenocarcinoma cells by transcriptionally regulating ZNF143 expression. Mei J, Liu Y, Sheng Y, Liu Y, Chen L, Wang H, Cheng M, Zhai Z, Xu L., Free PMC Article | 06/23/2023 |
ZNF143 regulates autophagic flux to alleviate myocardial ischemia/reperfusion injury through Raptor. | ZNF143 regulates autophagic flux to alleviate myocardial ischemia/reperfusion injury through Raptor. Rao P, Li C, Wang L, Jiang Y, Yang L, Li H, Yang P, Tao J, Lu D, Sun L. | 10/8/2022 |
ZNF143 Expression is Associated with COPD and Tumor Microenvironment in Non-Small Cell Lung Cancer. | ZNF143 Expression is Associated with COPD and Tumor Microenvironment in Non-Small Cell Lung Cancer. Feng Z, Yin Y, Liu B, Wang L, Chen M, Zhu Y, Zhang H, Sun D, Qin J., Free PMC Article | 04/23/2022 |
BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) promotes lung adenocarcinoma by interacting with Zinc Finger Protein ZNF143 and regulating glycolysis. | BUB1B (BUB1 Mitotic Checkpoint Serine/Threonine Kinase B) promotes lung adenocarcinoma by interacting with Zinc Finger Protein ZNF143 and regulating glycolysis. Zhou X, Yuan Y, Kuang H, Tang B, Zhang H, Zhang M., Free PMC Article | 02/26/2022 |
DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility. | DNA methylome analysis identifies BMI-related epigenetic changes associated with non-small cell lung cancer susceptibility. Li G, Meng H, Bai Y, Wei W, Feng Y, Li M, Li H, He M, Zhang X, Wei S, Li Y, Guo H., Free PMC Article | 12/18/2021 |
ZNF143-Mediated H3K9 Trimethylation Upregulates CDC6 by Activating MDIG in Hepatocellular Carcinoma. | ZNF143-Mediated H3K9 Trimethylation Upregulates CDC6 by Activating MDIG in Hepatocellular Carcinoma. Zhang L, Huo Q, Ge C, Zhao F, Zhou Q, Chen X, Tian H, Chen T, Xie H, Cui Y, Yao M, Li H, Li J. | 11/21/2020 |
ZNF143 Suppresses Cell Apoptosis and Promotes Proliferation in Gastric Cancer via ROS/p53 Axis. | ZNF143 Suppresses Cell Apoptosis and Promotes Proliferation in Gastric Cancer via ROS/p53 Axis. Zhang Y, Li Q, Wei S, Sun J, Zhang X, He L, Zhang L, Xu Z, Chen D., Free PMC Article | 10/10/2020 |
LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors. | LIN28B regulates transcription and potentiates MYCN-induced neuroblastoma through binding to ZNF143 at target gene promotors. Tao T, Shi H, Mariani L, Abraham BJ, Durbin AD, Zimmerman MW, Powers JT, Missios P, Ross KN, Perez-Atayde AR, Bulyk ML, Young RA, Daley GQ, Look AT., Free PMC Article | 09/26/2020 |
ZNF143 is dynamically bound to a subset of its interphase sites during mitosis. | ZNF143 is dynamically bound to a subset of its interphase sites during mitosis. Ye B, Shen W, Zhao Z. | 09/5/2020 |
Secretion of interleukin (IL)-8 was increased when ZNF143 expression was reduced. | Loss of zinc-finger protein 143 contributes to tumour progression by interleukin-8-CXCR axis in colon cancer. Verma V, Paek AR, Choi BK, Hong EK, You HJ., Free PMC Article | 08/1/2020 |
this study revealed that A1CF can upregulate the expression of FAM224A via strengthening its stability, which in turn, influenced the negative modulation of miR-590-3p on transcription factor ZNF143. | Inhibition of the aberrant A1CF-FAM224A-miR-590-3p-ZNF143 positive feedback loop attenuated malignant biological behaviors of glioma cells. Song Y, Shao L, Xue Y, Ruan X, Liu X, Yang C, Zheng J, Shen S, Chen J, Li Z, Liu Y., Free PMC Article | 12/7/2019 |
a subset of breast cancer cells with low expression of ZNF143 might exhibit better survival via an autophagic process by regulating the p53Beclin1 axis. | The Role of ZNF143 in Breast Cancer Cell Survival Through the NAD(P)H Quinone Dehydrogenase 1⁻p53⁻Beclin1 Axis Under Metabolic Stress. Paek AR, Mun JY, Jo MJ, Choi H, Lee YJ, Cheong H, Myung JK, Hong DW, Park J, Kim KH, You HJ., Free PMC Article | 11/30/2019 |
The zinc finger, ZNF143, binds to the CCCAGCAG site in the CEBPA promoter. | ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα. Gonzalez D, Luyten A, Bartholdy B, Zhou Q, Kardosova M, Ebralidze A, Swanson KD, Radomska HS, Zhang P, Kobayashi SS, Welner RS, Levantini E, Steidl U, Chong G, Collombet S, Choi MH, Friedman AD, Scott LM, Alberich-Jorda M, Tenen DG., Free PMC Article | 11/3/2018 |
The inhibition of ZNF143 activity by small molecules induced tumor regression. | YPC-21661 and YPC-22026, novel small molecules, inhibit ZNF143 activity in vitro and in vivo. Haibara H, Yamazaki R, Nishiyama Y, Ono M, Kobayashi T, Hokkyo-Itagaki A, Nishisaka F, Nishiyama H, Kurita A, Matsuzaki T, Izumi H, Kohno K., Free PMC Article | 09/16/2017 |
Data show that zinc finger protein 143 (ZNF143) promotes epithelial-mesenchymal transition (EMT) through regulating PI3K/AKT pathway in gastric cancer (GC) cells. | ZNF143 enhances metastasis of gastric cancer by promoting the process of EMT through PI3K/AKT signaling pathway. Wei S, Wang L, Zhang L, Li B, Li Z, Zhang Q, Wang J, Chen L, Sun G, Li Q, Xu H, Zhang D, Xu Z. | 02/25/2017 |
The results show that as an important partner of CTCF, ZNF143 helps establishing the conserved chromatin structure by cooperating with cohesin. | [ZNF143 is involved in CTCF-mediated chromatin interactions by cooperation with cohesin and other partners]. Ye BY, Shen WL, Wang D, Li P, Zhang Z, Shi ML, Zhang Y, Zhang FX, Zhao ZH. | 01/28/2017 |
ZNF143 is directly recruited to the promoter of genes engage in chromatin interactions, where it binds to its DNA recognition sequence. | ZNF143 provides sequence specificity to secure chromatin interactions at gene promoters. Bailey SD, Zhang X, Desai K, Aid M, Corradin O, Cowper-Sal Lari R, Akhtar-Zaidi B, Scacheri PC, Haibe-Kains B, Lupien M., Free PMC Article | 04/30/2016 |
THAP11, ZNF143, and HCF-1 form a mutually dependent complex on chromatin, which is independent of E2F occupancy. | Host cell factor-1 recruitment to E2F-bound and cell-cycle-control genes is mediated by THAP11 and ZNF143. Parker JB, Yin H, Vinckevicius A, Chakravarti D., Free PMC Article | 07/25/2015 |
ZNF143 expresses different 3'-untranslated regions (3'-UTR) as a result of alternative polyadenylation | ZNF143 is regulated through alternative 3'UTR isoforms. Ngondo RP, Carbon P. | 04/4/2015 |
High zinc-finger protein 143 is associated with cancer cell migration and invasion through ZEB1 and E-cadherin in colon cancer. | A role of zinc-finger protein 143 for cancer cell migration and invasion through ZEB1 and E-cadherin in colon cancer cells. Paek AR, Lee CH, You HJ. | 05/3/2014 |
HCFC1 is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1, and GABP transcription factor occupancy. | HCFC1 is a common component of active human CpG-island promoters and coincides with ZNF143, THAP11, YY1, and GABP transcription factor occupancy. Michaud J, Praz V, James Faresse N, Jnbaptiste CK, Tyagi S, Schütz F, Herr W., Free PMC Article | 10/26/2013 |
ZNF143 upregulated GPX1 activity and protecting cells from oxidative damage. | ZNF143 transcription factor mediates cell survival through upregulation of the GPX1 activity in the mitochondrial respiratory dysfunction. Lu W, Chen Z, Zhang H, Wang Y, Luo Y, Huang P., Free PMC Article | 06/1/2013 |