| Cellular glycan modification by B3GAT1 broadly restricts influenza virus infection. | Cellular glycan modification by B3GAT1 broadly restricts influenza virus infection.
Trimarco JD, Nelson SL, Chaparian RR, Wells AI, Murray NB, Azadi P, Coyne CB, Heaton NS., Free PMC Article | 11/5/2022 |
| We then examined several HNK-1-related antibodies, including the Cat-315 antibody, for reactions with HNK-1-capped core M2 glycans. Finally, we confirmed the increased HNK-1 epitope expression in demyelinated brains of cuprizone-fed mice. | Reactivity of anti-HNK-1 antibodies to branched O-mannose glycans associated with demyelination.
Sakuda K, Kizuka Y, Yamaguchi Y, Tanaka K, Ogiwara K, Segawa T, Hagiwara Y, Matsuo I, Ogawa H, Taniguchi N, Kitazume S. | 06/24/2017 |
| Results could lead to discovery of new roles of the human natural killer-1 (HNK-1) epitope in neural plasticity. | A Sulfated Glycosaminoglycan Linkage Region is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets.
Yabuno K, Morise J, Kizuka Y, Hashii N, Kawasaki N, Takahashi S, Miyata S, Izumikawa T, Kitagawa H, Takematsu H, Oka S., Free PMC Article | 07/2/2016 |
| Alpha-Klotho expression is associated with expression of the non-sulfated HNK-1 epitope. | α-Klotho mice demonstrate increased expression of the non-sulfated N-glycan form of the HNK-1 glyco-epitope in kidney tissue.
Akasaka-Manya K, Manya H, Kizuka Y, Oka S, Endo T. | 04/4/2015 |
| A linear HNK-1 mimetic peptide demonstrates potential as an efficient, feasible, and safe adjunct treatment for nerve injuries requiring surgical repair in cynomolgus monkeys. | Glycomimetic improves recovery after femoral injury in a non-human primate.
Irintchev A, Wu MM, Lee HJ, Zhu H, Feng YP, Liu YS, Bernreuther C, Loers G, You SW, Schachner M. | 05/26/2012 |
| the specific enzyme complex of beta4GalT-II with GlcAT-P plays an important role in the biosynthesis of HNK-1 carbohydrate. | Specific enzyme complex of beta-1,4-galactosyltransferase-II and glucuronyltransferase-P facilitates biosynthesis of N-linked human natural killer-1 (HNK-1) carbohydrate.
Kouno T, Kizuka Y, Nakagawa N, Yoshihara T, Asano M, Oka S., Free PMC Article | 12/10/2011 |
| HNK-1 epitope-carrying tenascin-C spliced variant regulates the proliferation of mouse embryonic neural stem cells. | HNK-1 epitope-carrying tenascin-C spliced variant regulates the proliferation of mouse embryonic neural stem cells.
Yagi H, Yanagisawa M, Suzuki Y, Nakatani Y, Ariga T, Kato K, Yu RK., Free PMC Article | 01/1/2011 |
| HNK-1 epitope on GluR2 regulates cell surface stability of GluR2 by modulating the interaction with N-cadherin | HNK-1 glyco-epitope regulates the stability of the glutamate receptor subunit GluR2 on the neuronal cell surface.
Morita I, Kakuda S, Takeuchi Y, Itoh S, Kawasaki N, Kizuka Y, Kawasaki T, Oka S., Free PMC Article | 01/21/2010 |
| TonEBP activation by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc | Activation of TonEBP by calcium controls {beta}1,3-glucuronosyltransferase-I expression, a key regulator of glycosaminoglycan synthesis in cells of the intervertebral disc.
Hiyama A, Gajghate S, Sakai D, Mochida J, Shapiro IM, Risbud MV., Free PMC Article | 01/21/2010 |
| the localization of HNK-1 carbohydrate was restricted partially in the brain of GlcAT-P-deficient mice | Distributions of glucuronyltransferases, GlcAT-P and GlcAT-S, and their target substrate, the HNK-1 carbohydrate epitope in the adult mouse brain with or without a targeted deletion of the GlcAT-P gene.
Inoue M, Kato K, Matsuhashi H, Kizuka Y, Kawasaki T, Oka S. | 01/21/2010 |
| In development, HNK-1-positive-cells and NCAM-positive cells were seen after P-21. These results suggest that the Schwann cells from the motor and the sensory fascicles have different subtypes. | Specific expression of an HNK-1 carbohydrate epitope and NCAM on femoral nerve Schwann cells in mice.
Saito H, Nakao Y, Takayama S, Toyama Y, Asou H. | 01/21/2010 |
| A 207 bp fragment of the 5'-upstream region of mouse GlcAT-P gene acts as a strong promoter in PC-12 cells, which express the HNK-1 epitope. | Molecular cloning and genomic analysis of mouse glucuronyltransferase involved in biosynthesis of the HNK-1 epitope.
Yamamoto S, Oka S, Saito-Ohara F, Inazawa J, Kawasaki T. | 01/21/2010 |
| HNK-1 deficient mice exhibit impaired synaptic plasticity and spatial learning. (HNK-1, CD57) | Mice deficient in nervous system-specific carbohydrate epitope HNK-1 exhibit impaired synaptic plasticity and spatial learning.
Yamamoto S, Oka S, Inoue M, Shimuta M, Manabe T, Takahashi H, Miyamoto M, Asano M, Sakagami J, Sudo K, Iwakura Y, Ono K, Kawasaki T. | 01/21/2010 |