| Structural basis for the interaction between the first SURP domain of the SF3A1 subunit in U2 snRNP and the human splicing factor SF1. | Structural basis for the interaction between the first SURP domain of the SF3A1 subunit in U2 snRNP and the human splicing factor SF1.
Nameki N, Takizawa M, Suzuki T, Tani S, Kobayashi N, Sakamoto T, Muto Y, Kuwasako K., Free PMC Article | 10/8/2022 |
| Deoxynivalenol globally affects the selection of 3' splice sites in human cells by suppressing the splicing factors, U2AF1 and SF1. | Deoxynivalenol globally affects the selection of 3' splice sites in human cells by suppressing the splicing factors, U2AF1 and SF1.
Hu Z, Sun Y, Chen J, Zhao Y, Qiao H, Chen R, Wen X, Deng Y, Wen J., Free PMC Article | 05/1/2021 |
| SF1 Phosphorylation Enhances Specific Binding to U2AF(65) and Reduces Binding to 3'-Splice-Site RNA | SF1 Phosphorylation Enhances Specific Binding to U2AF(65) and Reduces Binding to 3'-Splice-Site RNA.
Chatrikhi R, Wang W, Gupta A, Loerch S, Maucuer A, Kielkopf CL., Free PMC Article | 06/24/2017 |
| A novel function of SF1 in the initial recruitment of the U2 snRNP through direct interactions with two U2 snRNP-associated proteins. | Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.
Crisci A, Raleff F, Bagdiul I, Raabe M, Urlaub H, Rain JC, Krämer A., Free PMC Article | 04/30/2016 |
| Data suggest that post-translational processing of SF1 (phosphorylation of Ser20) down-regulates nuclear import of SF1 via alterations in kinetic interaction of SF1 nuclear localization signal (NLS) with NLS receptor isoforms. | Computational identification of post-translational modification-based nuclear import regulations by characterizing nuclear localization signal-import receptor interaction.
Lin JR, Liu Z, Hu J. | 10/31/2015 |
| We demonstrated that PRPF40B interacts directly with SF1 and associates with U2AF(65 | Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo.
Becerra S, Montes M, Hernández-Munain C, Suñé C., Free PMC Article | 04/18/2015 |
| Gomafu indirectly modulates the function of the splicing factors SF1 and Celf3 by sequestering these proteins into separate nuclear bodies. | Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1.
Ishizuka A, Hasegawa Y, Ishida K, Yanaka K, Nakagawa S., Free PMC Article | 02/28/2015 |
| The conserved SPSP motif phosphorylation and the SF1/U2AF interface are essential in vivo. | Structure of phosphorylated SF1 bound to U2AF⁶⁵ in an essential splicing factor complex.
Wang W, Maucuer A, Gupta A, Manceau V, Thickman KR, Bauer WJ, Kennedy SD, Wedekind JE, Green MR, Kielkopf CL., Free PMC Article | 08/3/2013 |
| Findings suggest that Zinc finger motif-1 (ZFM1) is an important factor for the stabilization of a contractile SMC phenotype under basal or mildly activating conditions. | Zinc finger motif-1 antagonizes PDGF-BB-induced growth and dedifferentiation of vascular smooth muscle cells.
Cattaruzza M, Nogoy N, Wojtowicz A, Hecker M. | 04/13/2013 |
| central ;mystery' domain of SF1 crystals belonged to space group C2 and have most probable solvent contents of 64, 52 or 39% with three, four or five molecules per asymmetric unit, respectively | Purification, crystallization and preliminary X-ray crystallographic analysis of a central domain of human splicing factor 1.
Gupta A, Kielkopf CL., Free PMC Article | 08/6/2011 |
| SF1 silencing affected alternative splicing of endogenous transcripts, establishing a previously unexpected role for SF1 and branch site-like sequences in splice site selection. | Analysis of in situ pre-mRNA targets of human splicing factor SF1 reveals a function in alternative splicing.
Corioni M, Antih N, Tanackovic G, Zavolan M, Krämer A., Free PMC Article | 06/4/2011 |
| the conformational changes that are induced by assembly of the SF1/U2AF(65)/RNA complex serve to position the pre-mRNA splice site optimally for subsequent stages of splicing. | RNA induces conformational changes in the SF1/U2AF65 splicing factor complex.
Gupta A, Jenkins JL, Kielkopf CL., Free PMC Article | 02/26/2011 |
| Puf60-UHM binds to ULM sequences in the splicing factors SF1, U2AF65, and SF3b155. | Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60.
Corsini L, Hothorn M, Stier G, Rybin V, Scheffzek K, Gibson TJ, Sattler M. | 01/21/2010 |
| SF1 and U2AF form extraspliceosomal complexes before and after taking part in the assembly of catalytic spliceosomes. | Splicing factors SF1 and U2AF associate in extraspliceosomal complexes.
Rino J, Desterro JM, Pacheco TR, Gadella TW Jr, Carmo-Fonseca M., Free PMC Article | 01/21/2010 |
| SF1 was essential for the induction of alternative mRNA splicing by the beta-catenin/TCF4 complex. | Involvement of splicing factor-1 in beta-catenin/T-cell factor-4-mediated gene transactivation and pre-mRNA splicing.
Shitashige M, Naishiro Y, Idogawa M, Honda K, Ono M, Hirohashi S, Yamada T. | 01/21/2010 |
| SF3a60, 66, and 120, but not SF1, are essential for pre-mRNA splicing | Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo.
Tanackovic G, Krämer A., Free PMC Article | 01/21/2010 |
| The KH-QUA2 region of SF1 defines an enlarged KH (hn RNP K) fold which is necessary and sufficient for intron branched point sequence (BPS) binding. | Structural basis for recognition of the intron branch site RNA by splicing factor 1.
Liu Z, Luyten I, Bottomley MJ, Messias AC, Houngninou-Molango S, Sprangers R, Zanier K, Krämer A, Sattler M. | 11/17/2001 |