| A founder variant expands the phenotype of WNT7B-related PDAC syndrome. | A founder variant expands the phenotype of WNT7B-related PDAC syndrome.
AlAbdi L, Rahbeeni Z, Maddirevula S, Helaby R, Abdulwahab F, Khan AO, Riley LG, Alhashem A, Chassaing N, Jamieson RV, Alkuraya FS. | 10/2/2024 |
| LINC01605 promotes malignant phenotypes of cervical cancer via miR-149-3p/WNT7B axis. | LINC01605 promotes malignant phenotypes of cervical cancer via miR-149-3p/WNT7B axis.
Kong X, Xiong Y, Li L. | 06/13/2024 |
| Bi-allelic variants in WNT7B disrupt the development of multiple organs in humans. | Bi-allelic variants in WNT7B disrupt the development of multiple organs in humans.
Bouasker S, Patel N, Greenlees R, Wellesley D, Fares Taie L, Almontashiri NA, Baptista J, Alghamdi MA, Boissel S, Martinovic J, Prokudin I, Holden S, Mudhar HS, Riley LG, Nassif C, Attie-Bitach T, Miguet M, Delous M, Ernest S, Plaisancié J, Calvas P, Rozet JM, Khan AO, Hamdan FF, Jamieson RV, Alkuraya FS, Michaud JL, Chassaing N. | 02/27/2023 |
| EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma. | EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.
Yu T, Zhou F, Tian W, Xu R, Wang B, Zeng A, Zhou Z, Li M, Wang Y, Zhang J. | 02/14/2023 |
| Inhibition of Wnt7b reduces the proliferation, invasion, and migration of colorectal cancer cells. | Inhibition of Wnt7b reduces the proliferation, invasion, and migration of colorectal cancer cells.
Chen S, Ding H, Wang K, Guo K. | 02/11/2023 |
| A WNT7B-m(6)A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis. | A WNT7B-m(6)A-TCF7L2 positive feedback loop promotes gastric cancer progression and metastasis.
Gao Q, Yang L, Shen A, Li Y, Li Y, Hu S, Yang R, Wang X, Yao X, Shen G., Free PMC Article | 03/5/2022 |
| Evaluation of WNT Signaling Pathway Gene Variants WNT7B rs6519955, SFRP4 rs17171229 and RSPO2 rs611744 in Patients with Dupuytren's Contracture. | Evaluation of WNT Signaling Pathway Gene Variants WNT7B rs6519955, SFRP4 rs17171229 and RSPO2 rs611744 in Patients with Dupuytren's Contracture.
Samulėnas G, Smalinskienė A, Rimdeika R, Braziulis K, Fomkinas M, Paškevičius R., Free PMC Article | 02/12/2022 |
| The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity. | The miR-34a/WNT7B modulates the sensitivity of cholangiocarcinoma cells to p53-mediated photodynamic therapy toxicity.
Han Y, Yang Y, Huang S, Yao L, Wu L. | 02/12/2022 |
| Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells. | Epigenetic regulation of Wnt7b expression by the cis-acting long noncoding RNA Lnc-Rewind in muscle stem cells.
Cipriano A, Macino M, Buonaiuto G, Santini T, Biferali B, Peruzzi G, Colantoni A, Mozzetta C, Ballarino M., Free PMC Article | 02/5/2022 |
| WNT7B represses epithelial-mesenchymal transition and stem-like properties in bladder urothelial carcinoma. | WNT7B represses epithelial-mesenchymal transition and stem-like properties in bladder urothelial carcinoma.
Na L, Wang Z, Bai Y, Sun Y, Dong D, Wang W, Zhao C. | 01/1/2022 |
| TCP1 regulates Wnt7b/beta-catenin pathway through P53 to influence the proliferation and migration of hepatocellular carcinoma cells. | TCP1 regulates Wnt7b/β-catenin pathway through P53 to influence the proliferation and migration of hepatocellular carcinoma cells.
Tang N, Cai X, Peng L, Liu H, Chen Y., Free PMC Article | 10/9/2021 |
| Extracellular vesicular Wnt7b mediates HPV E6-induced cervical cancer angiogenesis by activating the beta-catenin signaling pathway. | Extracellular vesicular Wnt7b mediates HPV E6-induced cervical cancer angiogenesis by activating the β-catenin signaling pathway.
Qiu JJ, Sun SG, Tang XY, Lin YY, Hua KQ., Free PMC Article | 08/7/2021 |
| Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer. | Fzd7/Wnt7b signaling contributes to stemness and chemoresistance in pancreatic cancer.
Zhang Z, Xu Y, Zhao C., Free PMC Article | 07/24/2021 |
| Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells. | Wnt7b-induced Sox11 functions enhance self-renewal and osteogenic commitment of bone marrow mesenchymal stem cells.
Yu F, Wu F, Li F, Liao X, Wang Y, Li X, Wang C, Shi Y, Ye L. | 07/10/2021 |
| Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells. | Combined Omics Approaches Reveal the Roles of Non-canonical WNT7B Signaling and YY1 in the Proliferation of Human Pancreatic Progenitor Cells.
Kimura A, Toyoda T, Iwasaki M, Hirama R, Osafune K. | 07/10/2021 |
| Activation of WNT7b autocrine eases metastasis of colorectal cancer via epithelial to mesenchymal transition and predicts poor prognosis. | Activation of WNT7b autocrine eases metastasis of colorectal cancer via epithelial to mesenchymal transition and predicts poor prognosis.
Jiang S, Li Q, Liu Y, Zhang H, Wang Q, Chen Y, Shi X, Li J, Zhang H, Zhang Y, Xia D, Wu M, Lin J, Zhang C, Pang S, Jiang J, Wen Y, Zhang P., Free PMC Article | 05/22/2021 |
| Association of WNT7B and RSPO1 with Axial Length in School Children. | Association of WNT7B and RSPO1 with Axial Length in School Children.
Lu SY, Tang SM, Li FF, Kam KW, Tam POS, Yip WWK, Young AL, Tham CC, Pang CP, Yam JC, Chen LJ., Free PMC Article | 01/2/2021 |
| Analysis of Wnt7B and BMP4 expression patterns in congenital pulmonary airway malformation. | Analysis of Wnt7B and BMP4 expression patterns in congenital pulmonary airway malformation.
Zhu H, Liu D, Jia H. | 09/26/2020 |
| miR-342-5p inhibits osteosarcoma cell growth, migration, invasion, and sensitivity to Doxorubicin through targeting Wnt7b. | miR-342-5p inhibits osteosarcoma cell growth, migration, invasion, and sensitivity to Doxorubicin through targeting Wnt7b.
Liu Q, Wang Z, Zhou X, Tang M, Tan W, Sun T, Deng Y., Free PMC Article | 09/19/2020 |
| High WNT7B expression is associated with glioma. | circ_0001730 promotes proliferation and invasion via the miR-326/Wnt7B axis in glioma cells.
Lu Y, Deng X, Xiao G, Zheng X, Ma L, Huang W. | 06/6/2020 |
| Study shows for the first time significant ultraviolet B induced upregulation of WNT7B, WNT10B and TCF7L2 in patients with psoriasis and suggests a potential role of these genes in psoriasis pathogenesis. | Narrowband UVB treatment induces expression of WNT7B, WNT10B and TCF7L2 in psoriasis skin.
Assarsson M, Söderman J, Duvetorp A, Mrowietz U, Skarstedt M, Seifert O., Free PMC Article | 02/15/2020 |
| Study demonstrates that GATA4 functions as a tumor suppressor in lung cancer. Mechanistically, GATA4 upregulates multiple miRNAs targeting TGFB2 mRNA and causes ensuing WNT7B downregulation and eventually triggers cell senescence. Targeting the TGF-beta signaling provides a potential way for the treatment of GATA4-deficient lung cancer. | Lung cancer deficient in the tumor suppressor GATA4 is sensitive to TGFBR1 inhibition.
Gao L, Hu Y, Tian Y, Fan Z, Wang K, Li H, Zhou Q, Zeng G, Hu X, Yu L, Zhou S, Tong X, Huang H, Chen H, Liu Q, Liu W, Zhang G, Zeng M, Zhou G, He Q, Ji H, Chen L., Free PMC Article | 05/4/2019 |
| Results provide evidence that Olig2 promotes Wnt7b expression in glioma cells. | A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment.
Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, Ghosh M, Tirosh I, Huillard E, Alvarez-Buylla A, Oldham MC, Persson AI, Weiss WA, Batchelor TT, Stemmer-Rachamimov A, Suvà ML, Phillips JJ, Aghi MK, Mehta S, Jain RK, Rowitch DH., Free PMC Article | 03/2/2019 |
| The results indicate robust evidence for association between WNT7B SNPs and central corneal thickness in South Indian pedigrees, and suggest that WNT7B SNPs can have population-specific effects on ocular quantitative traits. | Family-Based Genome-Wide Association Study of South Indian Pedigrees Supports WNT7B as a Central Corneal Thickness Locus.
Fan BJ, Chen X, Sondhi N, Sharmila PF, Soumittra N, Sripriya S, Sacikala S, Asokan R, Friedman DS, Pasquale LR, Gao XR, Vijaya L, Cooke Bailey J, Vitart V, MacGregor S, Hammond CJ, Khor CC, Haines JL, George R, Wiggs JL, Mexican American Glaucoma Genetic Study; International Glaucoma Genetics Consortium; and NEIGHBORHOOD Consortium., Free PMC Article | 02/23/2019 |
| We identified a novel genome-wide significant association rs10453441 in the WNT7B gene on chromosome 22 as a novel SNP for central corneal thickness in Latinos. | Genome-wide association study identifies WNT7B as a novel locus for central corneal thickness in Latinos.
Gao X, Nannini DR, Corrao K, Torres M, Chen YI, Fan BJ, Wiggs JL, International Glaucoma Genetics Consortium, Taylor KD, Gauderman WJ, Rotter JI, Varma R., Free PMC Article | 02/17/2018 |