| WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling. | WNT7A promotes tumorigenesis of head and neck squamous cell carcinoma via activating FZD7/JAK1/STAT3 signaling.
Huang Q, Xiao Y, Lan T, Lu Y, Huang L, Zheng D., Free PMC Article | 01/29/2024 |
| Down-regulated Wnt7a and GPR124 in early-onset preeclampsia placentas reduce invasion and migration of trophoblast cells. | Down-regulated Wnt7a and GPR124 in early-onset preeclampsia placentas reduce invasion and migration of trophoblast cells.
Shen Y, Cui Q, Xiao L, Wang L, Li Q, Zhang R, Chen Z, Niu J. | 01/12/2024 |
| Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling. | Molecular basis of Wnt biogenesis, secretion, and Wnt7-specific signaling.
Qi X, Hu Q, Elghobashi-Meinhardt N, Long T, Chen H, Li X., | 11/14/2023 |
| Role of Stromal Fibroblast-Induced WNT7A Associated with Cancer Cell Migration Through the AKT/CLDN1 Signaling Axis in Oral Squamous Cell Carcinoma. | Role of Stromal Fibroblast-Induced WNT7A Associated with Cancer Cell Migration Through the AKT/CLDN1 Signaling Axis in Oral Squamous Cell Carcinoma.
Kayamori K, Katsube KI, Hirai H, Harada H, Ikeda T. | 10/24/2023 |
| Association of Clinicopathologic and Molecular Tumor Features With Recurrence in Resected Early-Stage Epidermal Growth Factor Receptor-Positive Non-Small Cell Lung Cancer. | Association of Clinicopathologic and Molecular Tumor Features With Recurrence in Resected Early-Stage Epidermal Growth Factor Receptor-Positive Non-Small Cell Lung Cancer.
Saw SPL, Zhou S, Chen J, Lai G, Ang MK, Chua K, Kanesvaran R, Ng QS, Jain A, Tan WL, Rajasekaran T, Lim DWT, Tan A, Fong KW, Takano A, Cheng XM, Lim KH, Koh T, Ong BH, Tan EH, Toh CK, Skanderup AJ, Tan SH, Tan DSW., Free PMC Article | 01/29/2022 |
| Variants of WNT7A and GPR124 are associated with hemorrhagic transformation following intravenous thrombolysis in ischemic stroke. | Variants of WNT7A and GPR124 are associated with hemorrhagic transformation following intravenous thrombolysis in ischemic stroke.
Ta S, Rong X, Guo ZN, Jin H, Zhang P, Li F, Li Z, Lin L, Zheng C, Gu Q, Zhang Y, Liu W, Yang Y, Chang J., Free PMC Article | 12/11/2021 |
| Wnt7a promotes the osteogenic differentiation of human mesenchymal stem cells. | Wnt7a promotes the osteogenic differentiation of human mesenchymal stem cells.
Yang L, Li Q, Zhang J, Li P, An P, Wang C, Hu P, Zou X, Dou X, Zhu L., Free PMC Article | 11/22/2021 |
| lncRNA CTBP1-AS2 promotes proliferation and migration of glioma by modulating miR-370-3p-Wnt7a-mediated epithelial-mesenchymal transition. | lncRNA CTBP1-AS2 promotes proliferation and migration of glioma by modulating miR-370-3p-Wnt7a-mediated epithelial-mesenchymal transition.
Li Y, Zong J, Zhao C. | 06/12/2021 |
| Exogenous Expression of WNT7A in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents. | Exogenous Expression of WNT7A in Leukemia-Derived Cell Lines Induces Resistance to Chemotherapeutic Agents.
Alvarez-Zavala M, Barreto-Vargas C, Torres-Reyes LA, De la Peña-Castro RF, Aguilar-Lemarroy A, Jave-Suarez LF. | 06/5/2021 |
| circRNA_001275 upregulates Wnt7a expression by competitively sponging miR3703p to promote cisplatin resistance in esophageal cancer. | circRNA_001275 upregulates Wnt7a expression by competitively sponging miR‑370‑3p to promote cisplatin resistance in esophageal cancer.
Zou FW, Yang SZ, Li WY, Liu CY, Liu XH, Hu CH, Liu ZH, Xu S., Free PMC Article | 03/13/2021 |
| Wnt7a regulates high autophagic and inflammatory response of epidermis in high-glucose environment. | Wnt7a regulates high autophagic and inflammatory response of epidermis in high-glucose environment.
Wang W, Zhang F, Yan X, Tan Q. | 12/5/2020 |
| Roles of Wnt7a in embryo development, tissue homeostasis, and human diseases. | Roles of Wnt7a in embryo development, tissue homeostasis, and human diseases.
Lan L, Wang W, Huang Y, Bu X, Zhao C. | 10/3/2020 |
| Wnt7a, frequently silenced by CpG methylation, inhibits tumor growth and metastasis via suppressing epithelial-mesenchymal transition in gastric cancer. | Wnt7a, frequently silenced by CpG methylation, inhibits tumor growth and metastasis via suppressing epithelial-mesenchymal transition in gastric cancer.
Liu Y, Qiao Y, Zhang H, Li W, Zheng J. | 09/19/2020 |
| this study illustrated that overexpression of WNT7A inhibited cell viability and migration, which was likely attributed to the regulation of SKP2/P21. | WNT7A Overexpression Inhibits Growth and Migration of Hepatocellular Carcinoma via the β-Catenin Independent Pathway.
Lan L, Wang W, Huang Y, Zhao C, Bu X., Free PMC Article | 05/16/2020 |
| hypoxia induced high expression of WNT7A might promote the cell migration via enhancing the epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma. | High expression of WNT7A predicts poor prognosis and promote tumor metastasis in pancreatic ductal adenocarcinoma.
Wu DJ, Jiang YS, He RZ, Tao LY, Yang MW, Fu XL, Yang JY, Zhu K., Free PMC Article | 10/19/2019 |
| Wnt7a should be considered a novel oncogene, and a potential prognostic and therapeutic target for patients with TSCC. | Wnt7a predicts poor prognosis, and contributes to growth and metastasis in tongue squamous cell carcinoma.
Jia B, Qiu X, Chu H, Sun X, Xu S, Zhao X, Zhao J. | 03/9/2019 |
| results have identified an miR-370-3p/Wnt7a axis that controls UBC invasion through canonical Wnt/beta-catenin signaling, which may offer prognostic and therapeutic opportunities | Wnt7a activates canonical Wnt signaling, promotes bladder cancer cell invasion, and is suppressed by miR-370-3p.
Huang X, Zhu H, Gao Z, Li J, Zhuang J, Dong Y, Shen B, Li M, Zhou H, Guo H, Huang R, Yan J., Free PMC Article | 02/2/2019 |
| All exons of WNT7a in 570 schizophrenic patients and 563 controls were sequenced, but none were noted to be associated with schizophrenia. | Mutation analysis of the WNT7A gene in patients with schizophrenia.
Hu TM, Ping LY, Hsu SH, Tsai HY, Cheng MC. | 01/12/2019 |
| These results indicate that Wnt7a signaling inhibits inflammatory stimuli-induced catabolic gene expression in human articular chondrocytes and is sufficient to attenuate MMP activities and promote joint cartilage integrity in mouse experimental OA, demonstrating a novel effect of Wnt7a on regulating OA pathogenesis. | Wnt7a Inhibits IL-1β Induced Catabolic Gene Expression and Prevents Articular Cartilage Damage in Experimental Osteoarthritis.
Gibson AL, Hui Mingalone CK, Foote AT, Uchimura T, Zhang M, Zeng L., Free PMC Article | 10/27/2018 |
| Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines | Wnt7a induces a unique phenotype of monocyte-derived macrophages with lower phagocytic capacity and differential expression of pro- and anti-inflammatory cytokines.
Wallace J, Lutgen V, Avasarala S, St Croix B, Winn RA, Al-Harthi L., Free PMC Article | 08/18/2018 |
| This report deals with linkage studies and exome sequencing, disclosing a novel variant in WNT7A, c.934G>A (p.Gly312Ser), as the cause of this Santos syndrome. | Santos syndrome is caused by mutation in the WNT7A gene.
Alves LU, Santos S, Musso CM, Ezquina SA, Opitz JM, Kok F, Otto PA, Mingroni-Netto RC. | 07/21/2018 |
| Demonstrate a significant change in miRNA profile dependent on the assisted reproductive technology outcome affecting Wnt pathway. | Altered miRNA-profile dependent on ART outcome in early pregnancy targets Wnt-pathway.
Freis A, Keller A, Ludwig N, Meese E, Jauckus J, Rehnitz J, Capp E, Strowitzki T, Germeyer A. | 06/30/2018 |
| A homozygous novel WNT7A mutation was identified in a child with Al-Awadi-Raas-Rothschild syndrome accompanied by dental abnormalities and his parents with dental abnormalities. | Al-Awadi-Raas-Rothschild syndrome with dental anomalies and a novel WNT7A mutation.
Kantaputra PN, Kapoor S, Verma P, Kaewgahya M, Kawasaki K, Ohazama A, Ketudat Cairns JR. | 03/31/2018 |
| Activation of the WNT/CTNBB1 pathway via WNT7A might play a role in PTC development. | Paratubal Cyst Size Correlates With Obesity and Dysregulation of the Wnt Signaling Pathway.
Dietrich JE, Adeyemi O, Hakim J, Santos X, Bercaw-Pratt JL, Bournat JC, Chen CH, Jorgez CJ. | 10/21/2017 |
| Results show that Wnt7a expression is significantly upregulated in epithelial cells of ovarian cancer which correlates with STAT4 expression and provide evidence that STAT4 promotes ovarian cancer metastasis via tumor-derived Wnt7a-induced activation of cancer-associated fibroblasts. | An integrated analysis identifies STAT4 as a key regulator of ovarian cancer metastasis.
Zhao L, Ji G, Le X, Luo Z, Wang C, Feng M, Xu L, Zhang Y, Lau WB, Lau B, Yang Y, Lei L, Yang H, Xuan Y, Chen Y, Deng X, Yi T, Yao S, Zhao X, Wei Y, Zhou S. | 09/23/2017 |