| Identification of DNA methylation-regulated WEE1 with potential implications in prognosis and immunotherapy for low-grade glioma. | Identification of DNA methylation-regulated WEE1 with potential implications in prognosis and immunotherapy for low-grade glioma.
Zhong WJ, Zhang LZ, Yue F, Yuan L, Zhang Q, Li X, Lin L., Free PMC Article | 09/4/2024 |
| In silico and structure-based evaluation of deleterious mutations identified in human Chk1, Chk2, and Wee1 protein kinase. | In silico and structure-based evaluation of deleterious mutations identified in human Chk1, Chk2, and Wee1 protein kinase.
Colaco V, Goswami N, Goel VK, Srivastava SK, Lalrohlua P, Senthil Kumar N, Borah P, Baruah R, Varma AK. | 01/16/2024 |
| Circulating RNA ZFR promotes hepatocellular carcinoma cell proliferation and epithelial-mesenchymal transition process through miR-624-3p/WEE1 axis. | Circulating RNA ZFR promotes hepatocellular carcinoma cell proliferation and epithelial-mesenchymal transition process through miR-624-3p/WEE1 axis.
Zhang L, He S, Guan H, Zhao Y, Zhang D. | 01/8/2024 |
| E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma. | E2F8 exerts cancer-promoting effects by transcriptionally activating RRM2 and E2F8 knockdown synergizes with WEE1 inhibition in suppressing lung adenocarcinoma.
Liu K, Wang L, Lou Z, Guo L, Xu Y, Qi H, Fang Z, Mei L, Chen X, Zhang X, Shao J, Xiang X. | 12/6/2023 |
| Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-gammaH2AX-MDC1. | Wee1 promotes cell proliferation and imatinib resistance in chronic myeloid leukemia via regulating DNA damage repair dependent on ATM-γH2AX-MDC1.
Zeng F, Peng Y, Qin Y, Wang J, Jiang G, Feng W, Yuan Y., Free PMC Article | 03/3/2023 |
| ODF2L acts as a synthetic lethal partner with WEE1 inhibition in epithelial ovarian cancer models. | ODF2L acts as a synthetic lethal partner with WEE1 inhibition in epithelial ovarian cancer models.
Li J, Lu J, Xu M, Yang S, Yu T, Zheng C, Huang X, Pan Y, Chen Y, Long J, Zhang C, Huang H, Dai Q, Li B, Wang W, Yao S, Pan C., Free PMC Article | 01/21/2023 |
| Mitotic Checkpoints and the Role of WEE1 Inhibition in Head and Neck Squamous Cell Carcinoma. | Mitotic Checkpoints and the Role of WEE1 Inhibition in Head and Neck Squamous Cell Carcinoma.
Khan SN, Swiecicki PL, Doroshow DB. | 10/8/2022 |
| Verbascoside enhances radiosensitivity of hepatocellular carcinoma cells through regulating miR-101-3p/Wee1 axis. | Verbascoside enhances radiosensitivity of hepatocellular carcinoma cells through regulating miR-101-3p/Wee1 axis.
Sun L, Cai H, Zhou T, Xiang H, Long L. | 07/2/2022 |
| Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFalpha Resistance in Head and Neck Cancers. | Inhibiting WEE1 and IKK-RELA Crosstalk Overcomes TNFα Resistance in Head and Neck Cancers.
Hu Z, Viswanathan R, Cheng H, Chen J, Yang X, Huynh A, Clavijo P, An Y, Robbins Y, Silvin C, Allen C, Ormanoglu P, Martin S, Cornelius S, Saleh A, Chen Z, Van Waes C, Morgan EL., Free PMC Article | 06/11/2022 |
| WEE1 kinase is a therapeutic vulnerability in CIC-DUX4 undifferentiated sarcoma. | WEE1 kinase is a therapeutic vulnerability in CIC-DUX4 undifferentiated sarcoma.
Ponce RKM, Thomas NJ, Bui NQ, Kondo T, Okimoto RA., Free PMC Article | 04/16/2022 |
| miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1. | miR-138-5p Inhibits the Growth and Invasion of Glioma Cells by Regulating WEE1.
Gong J, Tang Z, Yu Z, Deng Z, Liu Y, Ren N, Wang L, He Z., Free PMC Article | 04/16/2022 |
| Long noncoding RNA NORAD acts as a ceRNA mediates gemcitabine resistance in bladder cancer by sponging miR-155-5p to regulate WEE1 expression. | Long noncoding RNA NORAD acts as a ceRNA mediates gemcitabine resistance in bladder cancer by sponging miR-155-5p to regulate WEE1 expression.
Yang Y, Zhang G, Li J, Gong R, Wang Y, Qin Y, Ping Q, Hu L. | 03/5/2022 |
| WEE1 Inhibitor: Clinical Development. | WEE1 Inhibitor: Clinical Development.
Kong A, Mehanna H., Free PMC Article | 02/26/2022 |
| WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity. | WEE1 kinase protects the stability of stalled DNA replication forks by limiting CDK2 activity.
Elbæk CR, Petrosius V, Benada J, Erichsen L, Damgaard RB, Sørensen CS. | 02/19/2022 |
| Gene-Gene Interactions of Gemcitabine Metabolizing-Enzyme Genes hCNT3 and WEE1 for Preventing Severe Gemcitabine-Induced Hematological Toxicity. | Gene-Gene Interactions of Gemcitabine Metabolizing-Enzyme Genes hCNT3 and WEE1 for Preventing Severe Gemcitabine-Induced Hematological Toxicity.
Li J, Chen B, Xi WQ, Yang C, Zhang WX. | 02/5/2022 |
| Acquired small cell lung cancer resistance to Chk1 inhibitors involves Wee1 up-regulation. | Acquired small cell lung cancer resistance to Chk1 inhibitors involves Wee1 up-regulation.
Zhao X, Kim IK, Kallakury B, Chahine JJ, Iwama E, Pierobon M, Petricoin E, McCutcheon JN, Zhang YW, Umemura S, Chen V, Wang C, Giaccone G., Free PMC Article | 01/15/2022 |
| Circ-SNAP47 (hsa_circ_0016760) and miR-625-5p are regulators of WEE1 in regulation of chemoresistance, growth and invasion of DDP-tolerant NSCLC cells via ceRNA pathway. | Circ-SNAP47 (hsa_circ_0016760) and miR-625-5p are regulators of WEE1 in regulation of chemoresistance, growth and invasion of DDP-tolerant NSCLC cells via ceRNA pathway.
Zou C, Rong F, Zeng Y, Zeng J, Wei R, Wei D. | 01/8/2022 |
| Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na(+) Channel 1.2 Macromolecular Complex. | Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na(+) Channel 1.2 Macromolecular Complex.
Dvorak NM, Tapia CM, Baumgartner TJ, Singh J, Laezza F, Singh AK., Free PMC Article | 12/18/2021 |
| The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer. | The KRAS-regulated kinome identifies WEE1 and ERK coinhibition as a potential therapeutic strategy in KRAS-mutant pancreatic cancer.
Diehl JN, Klomp JE, Snare KR, Hibshman PS, Blake DR, Kaiser ZD, Gilbert TSK, Baldelli E, Pierobon M, Papke B, Yang R, Hodge RG, Rashid NU, Petricoin EF 3rd, Herring LE, Graves LM, Cox AD, Der CJ., Free PMC Article | 12/18/2021 |
| The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers. | The mitotic checkpoint is a targetable vulnerability of carboplatin-resistant triple negative breast cancers.
Moens S, Zhao P, Baietti MF, Marinelli O, Van Haver D, Impens F, Floris G, Marangoni E, Neven P, Annibali D, Sablina AA, Amant F., Free PMC Article | 11/22/2021 |
| MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma. | MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma.
Ke XY, Chen Y, Tham VY, Lin RY, Dakle P, Nacro K, Puhaindran ME, Houghton P, Pang A, Lee VK, Ding LW, Gery S, Hill J, Chen L, Xu L, Koeffler HP., Free PMC Article | 10/16/2021 |
| Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target. | Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target.
Aka Y, Karakas B, Acikbas U, Basaga H, Gul O, Kutuk O. | 10/2/2021 |
| Quercetin radiosensitizes non-small cell lung cancer cells through the regulation of miR-16-5p/WEE1 axis. | Quercetin radiosensitizes non-small cell lung cancer cells through the regulation of miR-16-5p/WEE1 axis.
Wang Q, Chen Y, Lu H, Wang H, Feng H, Xu J, Zhang B. | 08/21/2021 |
| WEE1 inhibition induces glutamine addiction in T-cell acute lymphoblastic leukemia. | WEE1 inhibition induces glutamine addiction in T-cell acute lymphoblastic leukemia.
Hu J, Wang T, Xu J, Wu S, Wang L, Su H, Jiang J, Yue M, Wang J, Wang D, Li P, Zhou F, Liu Y, Qing G, Liu H., Free PMC Article | 08/7/2021 |
| The lncRNA XIST/miR-125b-2-3p axis modulates cell proliferation and chemotherapeutic sensitivity via targeting Wee1 in colorectal cancer. | The lncRNA XIST/miR-125b-2-3p axis modulates cell proliferation and chemotherapeutic sensitivity via targeting Wee1 in colorectal cancer.
Zeng ZL, Lu JH, Wang Y, Sheng H, Wang YN, Chen ZH, Wu QN, Zheng JB, Chen YX, Yang DD, Yu K, Mo HY, Hu JJ, Hu PS, Liu ZX, Ju HQ, Xu RH., Free PMC Article | 07/24/2021 |